DE2247538C2 - Antitussivum - Google Patents
AntitussivumInfo
- Publication number
- DE2247538C2 DE2247538C2 DE2247538A DE2247538A DE2247538C2 DE 2247538 C2 DE2247538 C2 DE 2247538C2 DE 2247538 A DE2247538 A DE 2247538A DE 2247538 A DE2247538 A DE 2247538A DE 2247538 C2 DE2247538 C2 DE 2247538C2
- Authority
- DE
- Germany
- Prior art keywords
- antitussive
- levopropoxyphene
- codeine
- orotic acid
- levopropoxyphenorotate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/52—Two oxygen atoms
- C07D239/54—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals
- C07D239/545—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals with other hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/557—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals with other hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms, e.g. orotic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Priority Applications (9)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE2247538A DE2247538C2 (de) | 1972-09-28 | 1972-09-28 | Antitussivum |
FR7410678A FR2264540B1 (US20080293856A1-20081127-C00150.png) | 1972-09-28 | 1974-03-20 | |
NL7403931.A NL157207B (nl) | 1972-09-28 | 1974-03-22 | Werkwijze voor het bereiden van een antihoestmiddel dat een zout van l-alfa-1,2-difenyl-2-propionyloxy-3-methyl-4-dimethylaminobutaan als actief bestanddeel bevat, aldus gevormd geneesmiddel, alsmede werkwijze voor het bereiden van dit zout. |
GB1292274A GB1409993A (en) | 1972-09-28 | 1974-03-22 | Antitussive |
US454501A US3917836A (en) | 1972-09-28 | 1974-03-25 | Antitussivum |
AU67224/74A AU6722474A (en) | 1972-09-28 | 1974-03-27 | Antitussive |
LU69722A LU69722A1 (US20080293856A1-20081127-C00150.png) | 1972-09-28 | 1974-03-27 | |
BE142738A BE813175A (fr) | 1972-09-28 | 1974-04-02 | Produit tussifuge |
CH490974A CH590850A5 (US20080293856A1-20081127-C00150.png) | 1972-09-28 | 1974-04-08 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE2247538A DE2247538C2 (de) | 1972-09-28 | 1972-09-28 | Antitussivum |
Publications (3)
Publication Number | Publication Date |
---|---|
DE2247538A1 DE2247538A1 (de) | 1974-05-02 |
DE2247538B1 DE2247538B1 (de) | 1974-07-18 |
DE2247538C2 true DE2247538C2 (de) | 1975-03-06 |
Family
ID=5857605
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE2247538A Expired DE2247538C2 (de) | 1972-09-28 | 1972-09-28 | Antitussivum |
Country Status (9)
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2415740C2 (de) * | 1974-04-01 | 1983-12-01 | Servomed Arznei GmbH & Co Pharma KG, 8000 München | Verwendung von Orotsäure bei der analgetischen Behandlung mit Dextropropoxyphen, Natriumsalicylat oder Metamizol |
JP4347041B2 (ja) * | 2001-06-11 | 2009-10-21 | 協和発酵バイオ株式会社 | 消炎、鎮咳組成物 |
US8034823B2 (en) * | 2005-02-22 | 2011-10-11 | Savvipharm Inc | Method of increasing drug oral bioavailability and compositions of less toxic orotate salts |
US7470672B2 (en) * | 2006-07-31 | 2008-12-30 | Savvipharm Inc. | Compositions and methods of reducing tissue levels of drugs when given as orotate derivatives |
-
1972
- 1972-09-28 DE DE2247538A patent/DE2247538C2/de not_active Expired
-
1974
- 1974-03-20 FR FR7410678A patent/FR2264540B1/fr not_active Expired
- 1974-03-22 GB GB1292274A patent/GB1409993A/en not_active Expired
- 1974-03-22 NL NL7403931.A patent/NL157207B/xx not_active IP Right Cessation
- 1974-03-25 US US454501A patent/US3917836A/en not_active Expired - Lifetime
- 1974-03-27 LU LU69722A patent/LU69722A1/xx unknown
- 1974-03-27 AU AU67224/74A patent/AU6722474A/en not_active Expired
- 1974-04-02 BE BE142738A patent/BE813175A/xx not_active IP Right Cessation
- 1974-04-08 CH CH490974A patent/CH590850A5/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
AU6722474A (en) | 1975-10-02 |
NL157207B (nl) | 1978-07-17 |
FR2264540B1 (US20080293856A1-20081127-C00150.png) | 1977-11-04 |
US3917836A (en) | 1975-11-04 |
DE2247538B1 (de) | 1974-07-18 |
CH590850A5 (US20080293856A1-20081127-C00150.png) | 1977-08-31 |
LU69722A1 (US20080293856A1-20081127-C00150.png) | 1974-07-17 |
DE2247538A1 (de) | 1974-05-02 |
FR2264540A1 (US20080293856A1-20081127-C00150.png) | 1975-10-17 |
GB1409993A (en) | 1975-10-15 |
BE813175A (fr) | 1974-10-02 |
NL7403931A (nl) | 1975-09-24 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
E77 | Valid patent as to the heymanns-index 1977 | ||
8339 | Ceased/non-payment of the annual fee |