DE2241698C2 - Verfahren zur Organerhaltung sowie Vorrichtung zum Durchführen dieses Verfahrens - Google Patents

Verfahren zur Organerhaltung sowie Vorrichtung zum Durchführen dieses Verfahrens

Info

Publication number
DE2241698C2
DE2241698C2 DE2241698A DE2241698A DE2241698C2 DE 2241698 C2 DE2241698 C2 DE 2241698C2 DE 2241698 A DE2241698 A DE 2241698A DE 2241698 A DE2241698 A DE 2241698A DE 2241698 C2 DE2241698 C2 DE 2241698C2
Authority
DE
Germany
Prior art keywords
perfusate
pump
gas
organ
air
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE2241698A
Other languages
German (de)
English (en)
Other versions
DE2241698A1 (de
Inventor
Roland Dr.med. Zürich Doerig
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CH1300071A external-priority patent/CH551741A/de
Priority claimed from CH447972A external-priority patent/CH569404A5/de
Application filed by Individual filed Critical Individual
Publication of DE2241698A1 publication Critical patent/DE2241698A1/de
Application granted granted Critical
Publication of DE2241698C2 publication Critical patent/DE2241698C2/de
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/10—Preservation of living parts
    • A01N1/16—Physical preservation processes
    • A01N1/165—Pressure processes, e.g. following predefined pressure changes over time
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/10—Preservation of living parts
    • A01N1/14—Mechanical aspects of preservation; Apparatus or containers therefor
    • A01N1/142—Apparatus
    • A01N1/143—Apparatus for organ perfusion

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Dentistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Thermotherapy And Cooling Therapy Devices (AREA)
DE2241698A 1971-09-02 1972-08-24 Verfahren zur Organerhaltung sowie Vorrichtung zum Durchführen dieses Verfahrens Expired DE2241698C2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH1300071A CH551741A (de) 1971-09-02 1971-09-02 Verfahren zur erhaltung menschlicher und tierischer organe und apparat zur ausfuehrung des verfahrens.
CH447972A CH569404A5 (en) 1972-03-24 1972-03-24 Portable disposable perfuser for living organs - e.g. kidney for transplant, using dry ice or respiratory gas

Publications (2)

Publication Number Publication Date
DE2241698A1 DE2241698A1 (de) 1973-03-08
DE2241698C2 true DE2241698C2 (de) 1982-08-26

Family

ID=25695571

Family Applications (1)

Application Number Title Priority Date Filing Date
DE2241698A Expired DE2241698C2 (de) 1971-09-02 1972-08-24 Verfahren zur Organerhaltung sowie Vorrichtung zum Durchführen dieses Verfahrens

Country Status (9)

Country Link
US (1) US3914954A (esLanguage)
JP (1) JPS4835688A (esLanguage)
CA (1) CA987601A (esLanguage)
DE (1) DE2241698C2 (esLanguage)
ES (1) ES406268A1 (esLanguage)
FR (1) FR2151092B1 (esLanguage)
GB (1) GB1398565A (esLanguage)
NL (1) NL7211941A (esLanguage)
SE (1) SE394580B (esLanguage)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
USRE31035E (en) 1974-07-22 1982-09-21 Hancock Laboratories, Inc. Arrangement for preparing natural tissue for implantation
DE3308688A1 (de) * 1983-03-11 1984-09-13 Erich Dipl.-Ing. 6507 Ingelheim Martin Verfahren zur schnellen unterkuehlung von organen und geweben

Families Citing this family (57)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3966401A (en) * 1974-07-01 1976-06-29 Hancock Laboratories Incorporated Preparing natural tissue for implantation so as to provide improved flexibility
US4050893A (en) 1974-07-22 1977-09-27 Hancock Laboratories, Inc. Arrangement for preparing natural tissue for implantation
US4186565A (en) * 1978-05-19 1980-02-05 Henry Ford Hospital Perfusion system for organ preservation
US4242883A (en) * 1979-04-02 1981-01-06 Henry Ford Hospital Liver preservation
US4314550A (en) * 1980-05-01 1982-02-09 The Trustees Of Boston University Method of treating an arrested heart
US4299919A (en) * 1980-06-30 1981-11-10 St. Louis University Perfusate redox potential controller
US4395492A (en) * 1981-06-03 1983-07-26 Res-Del Group Ltd. Perfusion chamber
EP0096997B1 (en) * 1982-06-04 1986-09-24 Hoxan Corporation Method of preserving organ and apparatus for preserving the same
US4473637A (en) * 1982-11-10 1984-09-25 Guibert, Colman & Associates System for processing an organ preparatory to transplant
US4837390A (en) * 1983-05-11 1989-06-06 Keyes Offshore, Inc. Hyperbaric organ preservation apparatus and method for preserving living organs
DE3317551A1 (de) * 1983-05-13 1984-11-15 Stephan Dipl.-Chem. Dr.rer.nat. 8000 München Nees Perfusionseinrichtung zum "in vitro"-bespuelen verankerungsabhaengiger biologischer zellsysteme
US4471629A (en) * 1983-05-31 1984-09-18 Mount Carmel Research And Education Corporation Method of freezing and transplant of kidneys and apparatus
US4462215A (en) * 1983-05-31 1984-07-31 Hoxan Corporation Method of preserving organ and apparatus for preserving the same
JPS6061502A (ja) * 1983-09-14 1985-04-09 Hoxan Corp 臓器保存処理のための潅流方法と潅流装置
GB8619437D0 (en) * 1986-08-08 1986-09-17 Bradley L Storage & refrigeration
US4951482A (en) * 1988-12-21 1990-08-28 Gilbert Gary L Hypothermic organ transport apparatus
JPH0653160B2 (ja) * 1989-08-18 1994-07-20 呉羽化学工業株式会社 拍動発生方法及び装置
JPH0454101A (ja) * 1990-06-25 1992-02-21 Tetsuo Takano 移植用腎臓の保存方法及び保存装置
US5157930A (en) * 1991-04-22 1992-10-27 Mcghee Samuel C Organ preservation apparatus
US5856081A (en) * 1991-07-08 1999-01-05 The American National Red Cross Computer controlled cryoprotectant perfusion apparatus
US5217860A (en) * 1991-07-08 1993-06-08 The American National Red Cross Method for preserving organs for transplantation by vitrification
US5723282A (en) 1991-07-08 1998-03-03 The American National Red Cross Method of preparing organs for vitrification
US5328821A (en) * 1991-12-12 1994-07-12 Robyn Fisher Cold and cryo-preservation methods for human tissue slices
US5338662A (en) * 1992-09-21 1994-08-16 Bio-Preserve Medical Corporation Organ perfusion device
US5362622A (en) * 1993-03-11 1994-11-08 Board Of Regents, The University Of Texas System Combined perfusion and oxygenation apparatus
US5356771A (en) * 1993-03-11 1994-10-18 Board Of Regents, The University Of Texas System Combined perfusion and oxygenation organ preservation apparatus
US5586438A (en) * 1995-03-27 1996-12-24 Organ, Inc. Portable device for preserving organs by static storage or perfusion
US5799660A (en) * 1996-02-09 1998-09-01 The Ohio State Research Foundation Methods for evaluating efficacy of anti-inflammatory on drugs on joint inflammation
US5965433A (en) * 1996-05-29 1999-10-12 Trans D.A.T.A. Service, Inc. Portable perfusion/oxygenation module having mechanically linked dual pumps and mechanically actuated flow control for pulsatile cycling of oxygenated perfusate
US7749693B2 (en) * 1998-09-29 2010-07-06 Lifeline Scientific, Inc. Method of determining that an organ is not suitable for transplantation and using it for testing substances
US6977140B1 (en) * 1998-09-29 2005-12-20 Organ Recovery Systems, Inc. Method for maintaining and/or restoring viability of organs
US6673594B1 (en) 1998-09-29 2004-01-06 Organ Recovery Systems Apparatus and method for maintaining and/or restoring viability of organs
NL1013524C2 (nl) * 1999-11-08 2001-05-09 Univ Amsterdam Inrichting voor machinale orgaanperfusie gedurende de transportfase van een donororgaan.
US6677150B2 (en) 2001-09-14 2004-01-13 Organ Transport Systems, Inc. Organ preservation apparatus and methods
US20030073227A1 (en) * 2001-09-28 2003-04-17 Hull Harry F. Simple, fully transportable device for maintaining an excised heart in optimum condition for transplantation
ATE363233T1 (de) * 2002-08-23 2007-06-15 Organ Recovery Systems Verbindungsanordnungen, insbesondere für transplantationsorgane
USD531319S1 (en) 2003-04-04 2006-10-31 Organ Recovery Systems Tube frame for organ transporter
WO2004089085A2 (en) * 2003-04-04 2004-10-21 Organ Recovery Systems, Inc. Device for separating gas from a liquid path
USD531320S1 (en) 2003-04-04 2006-10-31 Organ Recovery Systems Cassette for organ transporter
US7678563B2 (en) 2003-04-04 2010-03-16 Organ Recovery Systems, Inc. Method and apparatus for controlling air pressure in an organ or tissue container
NL1024022C2 (nl) * 2003-07-30 2005-02-01 Technologiestichting Stw Draagbare preservatie-inrichting voor een donororgaan.
US20050153271A1 (en) * 2004-01-13 2005-07-14 Wenrich Marshall S. Organ preservation apparatus and methods
NL1028848C2 (nl) * 2005-04-22 2006-10-24 Doorzand Airdrive B V Inrichting voor het transporteren van een orgaan.
EP2278874B1 (en) 2008-04-22 2019-03-20 The Board of Regents of The University of Texas System Fluidics-based pulsatile perfusion organ preservation device
WO2011002926A2 (en) 2009-07-01 2011-01-06 The General Hospital Corporation Isolated adult cells, artificial organs,rehabilitated organs, research rools, organ encasements, organ perfusion systems, and methods for preparing and utilizing the same
US10575515B2 (en) 2010-05-04 2020-03-03 The General Hospital Corporation Methods and compositions for preserving tissues and organs
US9642625B2 (en) 2011-04-29 2017-05-09 Lifeline Scientific, Inc. Cannula for a donor organ with or without an aortic cuff or patch
US8828034B2 (en) 2011-04-29 2014-09-09 Lifeline Scientific, Inc. Cannula
US9022978B2 (en) 2011-04-29 2015-05-05 Lifeline Scientific, Inc. Universal sealring cannula
WO2015138832A1 (en) 2014-03-13 2015-09-17 The General Hospital Corporation Devices and methods to improve and assess viability of human livers
CA3061643A1 (en) * 2017-04-28 2018-11-01 Lifeline Scientific, Inc. Organ transporter with supplemental oxygenation system
WO2018232110A1 (en) 2017-06-14 2018-12-20 The General Hospital Corporation High subzero cryopreservation
CN111867528A (zh) * 2018-01-19 2020-10-30 马里兰大学巴尔的摩分校 用于在运输期间处理人体器官的技术
WO2019232268A1 (en) 2018-05-30 2019-12-05 Mustafa Korkut Uygun Cryopreservation of tissues and organs
US12356982B2 (en) * 2019-03-14 2025-07-15 Lifeline Scientific, Inc. Oxygenator device
US12389903B2 (en) 2021-09-23 2025-08-19 Lifeline Scientific, Inc. Low fluid level detection device
JPWO2023068158A1 (esLanguage) * 2021-10-18 2023-04-27

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3214937A (en) * 1963-02-26 1965-11-02 Cannon Instr Company Constant temperature bath
US3406531A (en) * 1964-08-25 1968-10-22 Emil S. Swenson Apparatus for maintaining organs in a completely viable state
US3267687A (en) * 1964-09-22 1966-08-23 Cannon Instr Company Constant temperature device
US3545221A (en) * 1967-05-22 1970-12-08 Swenko Research & Dev Inc Apparatus for maintaining organs in vitro in a completely viable state
US3475918A (en) * 1967-11-13 1969-11-04 Technology Uk Cooling apparatus employing carbon dioxide
FR1577356A (esLanguage) * 1968-04-04 1969-08-08
DE1938275A1 (de) * 1969-03-11 1970-10-08 Baxter Laboratories Inc Perfusionseinheit fuer ein Organ od.dgl.
BE755423A (fr) * 1969-10-06 1971-02-01 Baxter Laboratories Inc Procede et appareil pour la conservation d'organes

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
USRE31035E (en) 1974-07-22 1982-09-21 Hancock Laboratories, Inc. Arrangement for preparing natural tissue for implantation
DE3308688A1 (de) * 1983-03-11 1984-09-13 Erich Dipl.-Ing. 6507 Ingelheim Martin Verfahren zur schnellen unterkuehlung von organen und geweben

Also Published As

Publication number Publication date
ES406268A1 (es) 1976-01-16
DE2241698A1 (de) 1973-03-08
SE394580B (sv) 1977-07-04
FR2151092B1 (esLanguage) 1975-01-03
JPS4835688A (esLanguage) 1973-05-25
FR2151092A1 (esLanguage) 1973-04-13
GB1398565A (en) 1975-06-25
US3914954A (en) 1975-10-28
NL7211941A (esLanguage) 1973-03-06
CA987601A (en) 1976-04-20

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Legal Events

Date Code Title Description
D2 Grant after examination
8380 Miscellaneous part iii

Free format text: DER VERTRETER IST NACHZUTRAGEN GRUENECKER, A., DIPL.-ING. KINKELDEY, H., DR.-ING. STOCKMAIR, W., DR.-ING. AE.E. SCHUMANN, K., DIPL.-PHYS.DR.RER.NAT. JAKOB, P., DIPL.-ING. BEZOLD, G., DIPL.-CHEM.DR.RER.NAT., PAT.-ANW., 8000 MUENCHEN

8339 Ceased/non-payment of the annual fee