DE2160042A1 - Dipeptidester und Verfahren zu ihrer Herstellung - Google Patents
Dipeptidester und Verfahren zu ihrer HerstellungInfo
- Publication number
- DE2160042A1 DE2160042A1 DE19712160042 DE2160042A DE2160042A1 DE 2160042 A1 DE2160042 A1 DE 2160042A1 DE 19712160042 DE19712160042 DE 19712160042 DE 2160042 A DE2160042 A DE 2160042A DE 2160042 A1 DE2160042 A1 DE 2160042A1
- Authority
- DE
- Germany
- Prior art keywords
- coor
- radical
- group
- dipeptide
- protected
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 108010016626 Dipeptides Proteins 0.000 title claims description 28
- 238000000034 method Methods 0.000 title claims description 25
- 150000002148 esters Chemical class 0.000 title claims description 16
- 238000002360 preparation method Methods 0.000 title claims description 16
- -1 cyclic alkyl radical Chemical class 0.000 claims description 35
- 150000001875 compounds Chemical class 0.000 claims description 30
- 125000004432 carbon atom Chemical group C* 0.000 claims description 10
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 claims description 10
- QTBSBXVTEAMEQO-UHFFFAOYSA-N acetic acid Substances CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 claims description 9
- 125000003277 amino group Chemical group 0.000 claims description 8
- 229910052799 carbon Inorganic materials 0.000 claims description 6
- 125000006239 protecting group Chemical group 0.000 claims description 6
- KDLHZDBZIXYQEI-UHFFFAOYSA-N Palladium Chemical compound [Pd] KDLHZDBZIXYQEI-UHFFFAOYSA-N 0.000 claims description 4
- 238000005984 hydrogenation reaction Methods 0.000 claims description 4
- CKLJMWTZIZZHCS-REOHCLBHSA-N L-aspartic acid Chemical class OC(=O)[C@@H](N)CC(O)=O CKLJMWTZIZZHCS-REOHCLBHSA-N 0.000 claims description 3
- BQOWUDKEXDCGQS-UHFFFAOYSA-N [CH]1CCCC1 Chemical compound [CH]1CCCC1 BQOWUDKEXDCGQS-UHFFFAOYSA-N 0.000 claims description 3
- YUDRVAHLXDBKSR-UHFFFAOYSA-N [CH]1CCCCC1 Chemical compound [CH]1CCCCC1 YUDRVAHLXDBKSR-UHFFFAOYSA-N 0.000 claims description 3
- IIVWHGMLFGNMOW-UHFFFAOYSA-N 2-methylpropane Chemical compound C[C](C)C IIVWHGMLFGNMOW-UHFFFAOYSA-N 0.000 claims description 2
- HNUALPPJLMYHDK-UHFFFAOYSA-N C[CH]C Chemical compound C[CH]C HNUALPPJLMYHDK-UHFFFAOYSA-N 0.000 claims description 2
- 125000001584 benzyloxycarbonyl group Chemical group C(=O)(OCC1=CC=CC=C1)* 0.000 claims description 2
- WCYWZMWISLQXQU-UHFFFAOYSA-N methyl Chemical compound [CH3] WCYWZMWISLQXQU-UHFFFAOYSA-N 0.000 claims description 2
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- 238000006243 chemical reaction Methods 0.000 description 11
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- 235000010469 Glycine max Nutrition 0.000 description 3
- KFZMGEQAYNKOFK-UHFFFAOYSA-N Isopropanol Chemical compound CC(C)O KFZMGEQAYNKOFK-UHFFFAOYSA-N 0.000 description 3
- OFOBLEOULBTSOW-UHFFFAOYSA-N Malonic acid Chemical compound OC(=O)CC(O)=O OFOBLEOULBTSOW-UHFFFAOYSA-N 0.000 description 3
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- 238000012360 testing method Methods 0.000 description 3
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- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 description 2
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- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 description 2
- DHMQDGOQFOQNFH-UHFFFAOYSA-N Glycine Chemical compound NCC(O)=O DHMQDGOQFOQNFH-UHFFFAOYSA-N 0.000 description 2
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- 125000004429 atom Chemical group 0.000 description 2
- WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 description 2
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- 235000014438 salad dressings Nutrition 0.000 description 1
- 235000013580 sausages Nutrition 0.000 description 1
- 235000014102 seafood Nutrition 0.000 description 1
- 235000020994 smoked meat Nutrition 0.000 description 1
- 238000002791 soaking Methods 0.000 description 1
- 239000011734 sodium Substances 0.000 description 1
- 229910052708 sodium Inorganic materials 0.000 description 1
- 229910000030 sodium bicarbonate Inorganic materials 0.000 description 1
- 235000017557 sodium bicarbonate Nutrition 0.000 description 1
- 235000010288 sodium nitrite Nutrition 0.000 description 1
- 229910000679 solder Inorganic materials 0.000 description 1
- 239000000600 sorbitol Substances 0.000 description 1
- 235000014347 soups Nutrition 0.000 description 1
- 238000005507 spraying Methods 0.000 description 1
- 239000007858 starting material Substances 0.000 description 1
- 239000000021 stimulant Substances 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 125000000999 tert-butyl group Chemical group [H]C([H])([H])C(*)(C([H])([H])[H])C([H])([H])[H] 0.000 description 1
- 229940034610 toothpaste Drugs 0.000 description 1
- 239000000606 toothpaste Substances 0.000 description 1
- 231100000820 toxicity test Toxicity 0.000 description 1
- 238000012546 transfer Methods 0.000 description 1
- 235000013311 vegetables Nutrition 0.000 description 1
- 235000021419 vinegar Nutrition 0.000 description 1
- 239000000052 vinegar Substances 0.000 description 1
- 235000019154 vitamin C Nutrition 0.000 description 1
- 239000011718 vitamin C Substances 0.000 description 1
- 235000008939 whole milk Nutrition 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06104—Dipeptides with the first amino acid being acidic
- C07K5/06113—Asp- or Asn-amino acid
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L27/00—Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
- A23L27/30—Artificial sweetening agents
- A23L27/31—Artificial sweetening agents containing amino acids, nucleotides, peptides or derivatives
- A23L27/32—Artificial sweetening agents containing amino acids, nucleotides, peptides or derivatives containing dipeptides or derivatives
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Nutrition Science (AREA)
- Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Seasonings (AREA)
- Non-Alcoholic Beverages (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP10788070 | 1970-12-05 | ||
| JP45114586A JPS4932070B1 (enrdf_load_stackoverflow) | 1970-12-18 | 1970-12-18 | |
| JP46065358A JPS4828672A (enrdf_load_stackoverflow) | 1971-08-26 | 1971-08-26 | |
| JP46094361A JPS5013353B2 (enrdf_load_stackoverflow) | 1971-11-24 | 1971-11-24 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE2160042A1 true DE2160042A1 (de) | 1972-06-29 |
Family
ID=27464573
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE19712160042 Pending DE2160042A1 (de) | 1970-12-05 | 1971-12-03 | Dipeptidester und Verfahren zu ihrer Herstellung |
Country Status (8)
| Country | Link |
|---|---|
| AU (1) | AU454368B2 (enrdf_load_stackoverflow) |
| BE (1) | BE776205A (enrdf_load_stackoverflow) |
| CH (1) | CH577277A5 (enrdf_load_stackoverflow) |
| DE (1) | DE2160042A1 (enrdf_load_stackoverflow) |
| FR (1) | FR2117384A5 (enrdf_load_stackoverflow) |
| GB (1) | GB1374588A (enrdf_load_stackoverflow) |
| NL (1) | NL7116543A (enrdf_load_stackoverflow) |
| SE (1) | SE375769B (enrdf_load_stackoverflow) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2007099650A1 (en) * | 2006-03-01 | 2007-09-07 | Fukuoka Prefectural Government | Peptide lipid-containing carrier and method for introducing compound into cells using same |
-
1971
- 1971-12-01 NL NL7116543A patent/NL7116543A/xx unknown
- 1971-12-02 CH CH1753671A patent/CH577277A5/xx not_active IP Right Cessation
- 1971-12-03 FR FR7143535A patent/FR2117384A5/fr not_active Expired
- 1971-12-03 DE DE19712160042 patent/DE2160042A1/de active Pending
- 1971-12-03 SE SE7115565A patent/SE375769B/xx unknown
- 1971-12-03 GB GB5622271A patent/GB1374588A/en not_active Expired
- 1971-12-03 BE BE776205A patent/BE776205A/xx unknown
- 1971-12-06 AU AU36527/71A patent/AU454368B2/en not_active Expired
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2007099650A1 (en) * | 2006-03-01 | 2007-09-07 | Fukuoka Prefectural Government | Peptide lipid-containing carrier and method for introducing compound into cells using same |
| US8299129B2 (en) | 2006-03-01 | 2012-10-30 | Fukuoka Prefectural Government | Peptide lipid-containing carrier and method for introducing compound into cells using same |
Also Published As
| Publication number | Publication date |
|---|---|
| NL7116543A (enrdf_load_stackoverflow) | 1972-06-07 |
| BE776205A (enrdf_load_stackoverflow) | 1972-04-04 |
| GB1374588A (en) | 1974-11-20 |
| AU3652771A (en) | 1973-06-14 |
| CH577277A5 (enrdf_load_stackoverflow) | 1976-07-15 |
| SE375769B (enrdf_load_stackoverflow) | 1975-04-28 |
| FR2117384A5 (enrdf_load_stackoverflow) | 1972-07-21 |
| AU454368B2 (en) | 1974-10-31 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| OHA | Expiration of time for request for examination |