DE2124640C2 - 1-Methyl-9,10-dihydrolysergyl-omega-nitro-L-argininol sowie seine Salze und diese Verbindungen enthaltende Arzneimittel - Google Patents

1-Methyl-9,10-dihydrolysergyl-omega-nitro-L-argininol sowie seine Salze und diese Verbindungen enthaltende Arzneimittel

Info

Publication number
DE2124640C2
DE2124640C2 DE19712124640 DE2124640A DE2124640C2 DE 2124640 C2 DE2124640 C2 DE 2124640C2 DE 19712124640 DE19712124640 DE 19712124640 DE 2124640 A DE2124640 A DE 2124640A DE 2124640 C2 DE2124640 C2 DE 2124640C2
Authority
DE
Germany
Prior art keywords
methyl
nitro
acid
compounds
argininol
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE19712124640
Other languages
German (de)
English (en)
Other versions
DE2124640A1 (de
Inventor
Tibor Budpest Balogh
Jozsef Dr. Budapest Borsi
Geb. Karacsony Erzsebet Mago
Lajos Budapest Wolf
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Richter Gedeon Vegyeszeti Gyar Nyrt
Original Assignee
Richter Gedeon Vegyeszeti Gyar RT
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richter Gedeon Vegyeszeti Gyar RT filed Critical Richter Gedeon Vegyeszeti Gyar RT
Publication of DE2124640A1 publication Critical patent/DE2124640A1/de
Application granted granted Critical
Publication of DE2124640C2 publication Critical patent/DE2124640C2/de
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
    • C07D457/04—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 8
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
    • C07D457/04—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 8
    • C07D457/06—Lysergic acid amides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
    • C07D457/04—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 8
    • C07D457/06—Lysergic acid amides
    • C07D457/08—Lysergic acid amides in which the amide nitrogen is a member of a heterocyclic ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DE19712124640 1970-05-18 1971-05-18 1-Methyl-9,10-dihydrolysergyl-omega-nitro-L-argininol sowie seine Salze und diese Verbindungen enthaltende Arzneimittel Expired DE2124640C2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HUGO001135 1970-05-18

Publications (2)

Publication Number Publication Date
DE2124640A1 DE2124640A1 (de) 1972-11-02
DE2124640C2 true DE2124640C2 (de) 1983-02-03

Family

ID=10996683

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19712124640 Expired DE2124640C2 (de) 1970-05-18 1971-05-18 1-Methyl-9,10-dihydrolysergyl-omega-nitro-L-argininol sowie seine Salze und diese Verbindungen enthaltende Arzneimittel

Country Status (12)

Country Link
JP (1) JPS5634598B1 (enExample)
AT (1) AT347047B (enExample)
CA (1) CA924306A (enExample)
CH (2) CH590277A5 (enExample)
CS (1) CS179371B2 (enExample)
DE (1) DE2124640C2 (enExample)
DK (1) DK142874B (enExample)
GB (1) GB1345546A (enExample)
NL (1) NL172825C (enExample)
SE (2) SE396753B (enExample)
SU (1) SU400091A3 (enExample)
YU (1) YU35770B (enExample)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU169073B (enExample) * 1974-05-28 1976-09-28
US4064249A (en) * 1974-05-28 1977-12-20 Richter Gedeon Vegyeszeti Gyar Rt. Compounds with ergoline skeleton
HU172649B (hu) * 1975-04-24 1978-11-28 Gyogyszerkutato Intezet Sposob poluchenija novykh biologicheski aktivnykh lizergamidov
DE3001752A1 (de) * 1980-01-16 1981-07-30 Schering Ag Berlin Und Bergkamen, 1000 Berlin Verfahren zur herstellung von 8(alpha)-substituierten 6-methylergolinen
NL189462C (nl) * 1980-04-03 1993-04-16 Erba Carlo Spa Ergolinederivaten met antiprolactinische en/of antihypertensieve eigenschappen en farmaceutische preparaat daarvan.
US4902691A (en) * 1988-12-19 1990-02-20 Eli Lilly And Company Heteroalkylamides of (8-β)-1-alkyl-6-(substituted)ergolines useful for blocking 5HT2 receptors
US4914107A (en) * 1989-01-17 1990-04-03 Eli Lilly And Company Method for selectively blocking 5-HT2 receptors
US5441961A (en) * 1992-08-27 1995-08-15 Eli Lilly And Company Substituted cyclo or bicycloalkylamides of (8β)-6-(substituted) ergolines
CA2974113A1 (en) 2015-01-20 2016-07-28 Xoc Pharmaceuticals, Inc. Isoergoline compounds and uses thereof
BR112017015487A2 (pt) 2015-01-20 2018-01-30 Xoc Pharmaceuticals Inc Composto; composição; método de tratamento e/ou prevenção de enxaqueca, als, doença de alzheimer, doença de parkinson, distúrbios extrapirimidais, depressão, náusea, êmese, síndrome das pernas inquietas, insônia, agressão, doença de huntington, doença cardiopulmonar, fibrogênese, hipertensão arterial pulmonar, ansiedade, dependências a drogas, distonia, parassonia ou hiperlactinemia em um indivíduo; métodos de agonização dos receptores d2, 5-ht1d, 5-ht1a e 5-ht2c, em um indivíduo; método de antagonização do receptor d3 em um indivíduo; métodos de agonização seletiva dos receptores 5 -ht1d, e 5-ht2c, método de fornecimento de atividade de antagonista funcional no receptor 5 -ht2b ou no receptor 5-ht7, ou em ambos, em um indivíduo; método de fornecimento de atividade de antagonista funcional nos receptores adrenérgicos em um indivíduo
CA3064274A1 (en) 2017-06-01 2018-12-06 Xoc Pharmaceuticals, Inc. Ergoline derivatives for use in medicine
JP7461342B2 (ja) 2018-09-12 2024-04-03 イーテーエルエーセー・ベー・フェー クレーンのシステムおよび交換可能工具

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT192546B (de) * 1956-02-27 1957-10-25 Anton Von Waldheim Chemisch Ph Verfahren zur Herstellung von Dihydrolysergsäure und deren Derivaten

Also Published As

Publication number Publication date
NL7106834A (enExample) 1971-11-22
ATA428771A (de) 1978-04-15
GB1345546A (en) 1974-01-30
DK142874B (da) 1981-02-16
CH590277A5 (enExample) 1977-07-29
CH567506A5 (enExample) 1975-10-15
YU35770B (en) 1981-06-30
JPS5634598B1 (enExample) 1981-08-11
DK142874C (enExample) 1981-09-28
CS179371B2 (en) 1977-10-31
SU400091A3 (enExample) 1973-10-03
AT347047B (de) 1978-12-11
SE396753B (sv) 1977-10-03
SE416302B (sv) 1980-12-15
CA924306A (en) 1973-04-10
NL172825C (nl) 1983-11-01
NL172825B (nl) 1983-06-01
YU122971A (en) 1980-10-31
DE2124640A1 (de) 1972-11-02

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Legal Events

Date Code Title Description
OD Request for examination
D2 Grant after examination
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee