HU169073B - - Google Patents
Info
- Publication number
- HU169073B HU169073B HUGO1272A HUGO001272A HU169073B HU 169073 B HU169073 B HU 169073B HU GO1272 A HUGO1272 A HU GO1272A HU GO001272 A HUGO001272 A HU GO001272A HU 169073 B HU169073 B HU 169073B
- Authority
- HU
- Hungary
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
- C07D457/04—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 8
- C07D457/06—Lysergic acid amides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
- C07D457/02—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with hydrocarbon or substituted hydrocarbon radicals, attached in position 8
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Psychiatry (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Priority Applications (23)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HUGO1272A HU169073B (enExample) | 1974-05-28 | 1974-05-28 | |
| AT386375A AT346501B (de) | 1974-05-28 | 1975-05-21 | Verfahren zur herstellung von neuen verbindungen mit ergolin-struktur |
| US05/579,979 US4005089A (en) | 1974-05-28 | 1975-05-22 | Compounds with ergoline skeleton |
| AU81425/75A AU495690B2 (en) | 1974-05-28 | 1975-05-22 | New compounds with ergoline skeleton anda process forthe preparation thereof |
| GB2283775A GB1474337A (en) | 1974-05-28 | 1975-05-23 | Run-flat pneumatic tyre and wheel assembly |
| YU01355/75A YU135575A (en) | 1974-05-28 | 1975-05-25 | Process for obtsining new compounds of the ergoline structure |
| IL47361A IL47361A (en) | 1974-05-28 | 1975-05-26 | 8b-substituted-6-methyl ergoline derivatives and a process for the preparation thereof |
| DD186250A DD121639A5 (enExample) | 1974-05-28 | 1975-05-26 | |
| SE7505974A SE419548B (sv) | 1974-05-28 | 1975-05-26 | Analogiforfarande for framstellning av 1-metyl-dihydrolysegoyl-nitroargininol-dekanoat |
| BG030088A BG27374A3 (bg) | 1974-05-28 | 1975-05-26 | Метод за получаване на съединения с ерголинова структура |
| BE156729A BE829518A (fr) | 1974-05-28 | 1975-05-27 | Nouveaux composes comportant un squelette d'ergoline, leur procede de preparation et medicaments les contenant |
| FI751537A FI61897C (fi) | 1974-05-28 | 1975-05-27 | Foerfarande foer framstaellning av nya terapeutiskt anvaendbara n-(1-(acyloximetyl)-4-(omega-nitroguanidino)-butyl)-dihydrolysergamider samt syraadditionssalter daerav |
| PL1975180710A PL98944B1 (pl) | 1974-05-28 | 1975-05-27 | Sposob wytwarzania nowych zwiazkow o strukturze ergoliny |
| CA227,849A CA1051878A (en) | 1974-05-28 | 1975-05-27 | Compounds with ergoline skeleton and a process for the preparation thereof |
| DK235175A DK143801C (da) | 1974-05-28 | 1975-05-27 | Analogifremgangsmaade til fremstilling af dihydrolysergsyrederivater |
| FR7516377A FR2272671B1 (enExample) | 1974-05-28 | 1975-05-27 | |
| SU752144199A SU625612A3 (ru) | 1974-05-28 | 1975-05-27 | Способ получени эрголиновых соединений или их солей |
| NL7506276A NL7506276A (nl) | 1974-05-28 | 1975-05-28 | Werkwijze voor de bereiding van nieuwe ergolineder- ivaten. |
| DE19752523743 DE2523743A1 (de) | 1974-05-28 | 1975-05-28 | Verbindungen mit ergolinstruktur, solche enthaltende arzneimittel sowie verfahren zur herstellung derselben |
| ES437994A ES437994A1 (es) | 1974-05-28 | 1975-05-28 | Procedimiento para preparar compuestos con esqueleto de er- golina. |
| JP50063984A JPS5218718B2 (enExample) | 1974-05-28 | 1975-05-28 | |
| CS753741A CS194227B2 (en) | 1974-05-28 | 1975-05-28 | Method of producing derivatives of lysergic acid amide |
| US05/749,398 US4064249A (en) | 1974-05-28 | 1976-12-10 | Compounds with ergoline skeleton |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HUGO1272A HU169073B (enExample) | 1974-05-28 | 1974-05-28 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HU169073B true HU169073B (enExample) | 1976-09-28 |
Family
ID=10996767
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HUGO1272A HU169073B (enExample) | 1974-05-28 | 1974-05-28 |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US4005089A (enExample) |
| JP (1) | JPS5218718B2 (enExample) |
| AT (1) | AT346501B (enExample) |
| BE (1) | BE829518A (enExample) |
| BG (1) | BG27374A3 (enExample) |
| CA (1) | CA1051878A (enExample) |
| CS (1) | CS194227B2 (enExample) |
| DD (1) | DD121639A5 (enExample) |
| DE (1) | DE2523743A1 (enExample) |
| DK (1) | DK143801C (enExample) |
| ES (1) | ES437994A1 (enExample) |
| FI (1) | FI61897C (enExample) |
| FR (1) | FR2272671B1 (enExample) |
| GB (1) | GB1474337A (enExample) |
| HU (1) | HU169073B (enExample) |
| IL (1) | IL47361A (enExample) |
| NL (1) | NL7506276A (enExample) |
| PL (1) | PL98944B1 (enExample) |
| SE (1) | SE419548B (enExample) |
| SU (1) | SU625612A3 (enExample) |
| YU (1) | YU135575A (enExample) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4064249A (en) * | 1974-05-28 | 1977-12-20 | Richter Gedeon Vegyeszeti Gyar Rt. | Compounds with ergoline skeleton |
| HU172649B (hu) * | 1975-04-24 | 1978-11-28 | Gyogyszerkutato Intezet | Sposob poluchenija novykh biologicheski aktivnykh lizergamidov |
| HU172479B (hu) * | 1976-03-09 | 1978-09-28 | Gyogyszerkutato Intezet | Sposob poluchenija novykh soedinenij s ehrgolenovymi i |
| JPS577172Y2 (enExample) * | 1977-03-17 | 1982-02-10 | ||
| JPS582957U (ja) * | 1981-06-30 | 1983-01-10 | 松下電子工業株式会社 | 高圧ナトリウムランプ |
| IT1171432B (it) * | 1981-08-03 | 1987-06-10 | Fidia Farmaceutici | Amidi organiche derivate da lipidi azotati utilizzabili come farmaci |
| US4675322A (en) * | 1984-12-10 | 1987-06-23 | Eli Lilly And Company | 1-Substituted-6-n-propyl-8β-methylthio-methylergolines |
| DD238051A1 (de) * | 1985-06-10 | 1986-08-06 | Dresden Arzneimittel | Verfahren zur herstellung neuer lysergsaeureamide |
| SG181896A1 (en) * | 2009-12-23 | 2012-07-30 | Map Pharmaceuticals Inc | Novel ergoline analogs |
| WO2012177962A1 (en) | 2011-06-23 | 2012-12-27 | Map Pharmaceuticals, Inc. | Novel fluoroergoline analogs |
| AU2012355982A1 (en) | 2011-12-19 | 2014-07-10 | Map Pharmaceuticals, Inc. | Novel iso-ergoline derivatives |
| WO2013095708A1 (en) | 2011-12-21 | 2013-06-27 | Map Pharmaceuticals, Inc. | Novel neuromodulatory compounds |
| US9012640B2 (en) | 2012-06-22 | 2015-04-21 | Map Pharmaceuticals, Inc. | Cabergoline derivatives |
| BR112017015487A2 (pt) * | 2015-01-20 | 2018-01-30 | Xoc Pharmaceuticals Inc | Composto; composição; método de tratamento e/ou prevenção de enxaqueca, als, doença de alzheimer, doença de parkinson, distúrbios extrapirimidais, depressão, náusea, êmese, síndrome das pernas inquietas, insônia, agressão, doença de huntington, doença cardiopulmonar, fibrogênese, hipertensão arterial pulmonar, ansiedade, dependências a drogas, distonia, parassonia ou hiperlactinemia em um indivíduo; métodos de agonização dos receptores d2, 5-ht1d, 5-ht1a e 5-ht2c, em um indivíduo; método de antagonização do receptor d3 em um indivíduo; métodos de agonização seletiva dos receptores 5 -ht1d, e 5-ht2c, método de fornecimento de atividade de antagonista funcional no receptor 5 -ht2b ou no receptor 5-ht7, ou em ambos, em um indivíduo; método de fornecimento de atividade de antagonista funcional nos receptores adrenérgicos em um indivíduo |
| WO2018223065A1 (en) | 2017-06-01 | 2018-12-06 | Xoc Pharmaceuticals, Inc. | Ergoline derivatives for use in medicine |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2533699A (en) * | 1950-12-12 | Amines containing the king system | ||
| US2673850A (en) * | 1951-07-28 | 1954-03-30 | Sandoz Ag | Piperazides of the lysergic acid series |
| US2946796A (en) * | 1958-10-15 | 1960-07-26 | Grace W R & Co | Salts of ergot alkaloids |
| CH475252A (de) * | 1966-02-08 | 1969-07-15 | Sandoz Ag | Verfahren zur Herstellung neuer Lysergsäure-Derivate |
| SE396753B (sv) * | 1970-05-18 | 1977-10-03 | Richter Gedeon Vegyeszet | Analogiforfarande for framstellning av en forening tillhorande dihydrolysergsyraserien |
| US3901893A (en) * | 1970-05-18 | 1975-08-26 | Richter Gedeon Vegyeszet | New dihydro-lysergic acid derivative |
| IL41409A (en) * | 1972-02-04 | 1977-04-29 | Richter Gedeon Vegyeszet | Lysergic acid amides and process for their preparation |
-
1974
- 1974-05-28 HU HUGO1272A patent/HU169073B/hu unknown
-
1975
- 1975-05-21 AT AT386375A patent/AT346501B/de not_active IP Right Cessation
- 1975-05-22 US US05/579,979 patent/US4005089A/en not_active Expired - Lifetime
- 1975-05-23 GB GB2283775A patent/GB1474337A/en not_active Expired
- 1975-05-25 YU YU01355/75A patent/YU135575A/xx unknown
- 1975-05-26 SE SE7505974A patent/SE419548B/xx unknown
- 1975-05-26 IL IL47361A patent/IL47361A/xx unknown
- 1975-05-26 DD DD186250A patent/DD121639A5/xx unknown
- 1975-05-26 BG BG030088A patent/BG27374A3/xx unknown
- 1975-05-27 CA CA227,849A patent/CA1051878A/en not_active Expired
- 1975-05-27 SU SU752144199A patent/SU625612A3/ru active
- 1975-05-27 FR FR7516377A patent/FR2272671B1/fr not_active Expired
- 1975-05-27 FI FI751537A patent/FI61897C/fi not_active IP Right Cessation
- 1975-05-27 BE BE156729A patent/BE829518A/xx not_active IP Right Cessation
- 1975-05-27 PL PL1975180710A patent/PL98944B1/pl unknown
- 1975-05-27 DK DK235175A patent/DK143801C/da not_active IP Right Cessation
- 1975-05-28 NL NL7506276A patent/NL7506276A/xx not_active Application Discontinuation
- 1975-05-28 JP JP50063984A patent/JPS5218718B2/ja not_active Expired
- 1975-05-28 DE DE19752523743 patent/DE2523743A1/de not_active Withdrawn
- 1975-05-28 CS CS753741A patent/CS194227B2/cs unknown
- 1975-05-28 ES ES437994A patent/ES437994A1/es not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| BE829518A (fr) | 1975-09-15 |
| DK143801B (da) | 1981-10-12 |
| FR2272671B1 (enExample) | 1978-10-06 |
| GB1474337A (en) | 1977-05-25 |
| PL98944B1 (pl) | 1978-05-31 |
| DK143801C (da) | 1982-03-22 |
| ES437994A1 (es) | 1977-01-16 |
| FI751537A7 (enExample) | 1975-11-29 |
| FR2272671A1 (enExample) | 1975-12-26 |
| ATA386375A (de) | 1978-03-15 |
| FI61897C (fi) | 1982-10-11 |
| IL47361A (en) | 1979-11-30 |
| JPS516998A (enExample) | 1976-01-20 |
| AT346501B (de) | 1978-11-10 |
| IL47361A0 (en) | 1975-07-28 |
| SU625612A3 (ru) | 1978-09-25 |
| DE2523743A1 (de) | 1975-12-18 |
| DK235175A (da) | 1975-11-29 |
| JPS5218718B2 (enExample) | 1977-05-24 |
| CS194227B2 (en) | 1979-11-30 |
| DD121639A5 (enExample) | 1976-08-12 |
| AU8142575A (en) | 1976-11-25 |
| CA1051878A (en) | 1979-04-03 |
| NL7506276A (nl) | 1975-12-02 |
| US4005089A (en) | 1977-01-25 |
| YU135575A (en) | 1982-06-30 |
| SE419548B (sv) | 1981-08-10 |
| BG27374A3 (bg) | 1979-10-12 |
| SE7505974L (sv) | 1975-12-01 |
| FI61897B (fi) | 1982-06-30 |