CS194227B2 - Method of producing derivatives of lysergic acid amide - Google Patents

Method of producing derivatives of lysergic acid amide

Info

Publication number
CS194227B2
CS194227B2 CS753741A CS374175A CS194227B2 CS 194227 B2 CS194227 B2 CS 194227B2 CS 753741 A CS753741 A CS 753741A CS 374175 A CS374175 A CS 374175A CS 194227 B2 CS194227 B2 CS 194227B2
Authority
CS
Czechoslovakia
Prior art keywords
acid amide
lysergic acid
producing derivatives
derivatives
producing
Prior art date
Application number
CS753741A
Other languages
English (en)
Inventor
Erzsebet Mago
Jozsef Borsi
Endre Csanyi
Katalin Pik
Lajos Wolf
Original Assignee
Richter Gedeon Vegyeszet
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richter Gedeon Vegyeszet filed Critical Richter Gedeon Vegyeszet
Publication of CS194227B2 publication Critical patent/CS194227B2/cs

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
    • C07D457/04—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 8
    • C07D457/06—Lysergic acid amides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
    • C07D457/02—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with hydrocarbon or substituted hydrocarbon radicals, attached in position 8

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Psychiatry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CS753741A 1974-05-28 1975-05-28 Method of producing derivatives of lysergic acid amide CS194227B2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HUGO1272A HU169073B (cs) 1974-05-28 1974-05-28

Publications (1)

Publication Number Publication Date
CS194227B2 true CS194227B2 (en) 1979-11-30

Family

ID=10996767

Family Applications (1)

Application Number Title Priority Date Filing Date
CS753741A CS194227B2 (en) 1974-05-28 1975-05-28 Method of producing derivatives of lysergic acid amide

Country Status (21)

Country Link
US (1) US4005089A (cs)
JP (1) JPS5218718B2 (cs)
AT (1) AT346501B (cs)
BE (1) BE829518A (cs)
BG (1) BG27374A3 (cs)
CA (1) CA1051878A (cs)
CS (1) CS194227B2 (cs)
DD (1) DD121639A5 (cs)
DE (1) DE2523743A1 (cs)
DK (1) DK143801C (cs)
ES (1) ES437994A1 (cs)
FI (1) FI61897C (cs)
FR (1) FR2272671B1 (cs)
GB (1) GB1474337A (cs)
HU (1) HU169073B (cs)
IL (1) IL47361A (cs)
NL (1) NL7506276A (cs)
PL (1) PL98944B1 (cs)
SE (1) SE419548B (cs)
SU (1) SU625612A3 (cs)
YU (1) YU135575A (cs)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4064249A (en) * 1974-05-28 1977-12-20 Richter Gedeon Vegyeszeti Gyar Rt. Compounds with ergoline skeleton
HU172649B (hu) * 1975-04-24 1978-11-28 Gyogyszerkutato Intezet Sposob poluchenija novykh biologicheski aktivnykh lizergamidov
HU172479B (hu) * 1976-03-09 1978-09-28 Gyogyszerkutato Intezet Sposob poluchenija novykh soedinenij s ehrgolenovymi i
JPS577172Y2 (cs) * 1977-03-17 1982-02-10
JPS582957U (ja) * 1981-06-30 1983-01-10 松下電子工業株式会社 高圧ナトリウムランプ
IT1171432B (it) * 1981-08-03 1987-06-10 Fidia Farmaceutici Amidi organiche derivate da lipidi azotati utilizzabili come farmaci
US4675322A (en) * 1984-12-10 1987-06-23 Eli Lilly And Company 1-Substituted-6-n-propyl-8β-methylthio-methylergolines
DD238051A1 (de) * 1985-06-10 1986-08-06 Dresden Arzneimittel Verfahren zur herstellung neuer lysergsaeureamide
US8710092B2 (en) * 2009-12-23 2014-04-29 Map Pharmaceuticals, Inc. Substituted indolo 4,3 FG quinolines useful for treating migraine
BR112013033339A2 (pt) 2011-06-23 2016-08-16 Map Pharmaceuticals Inc análogos de fluorergolina
SG11201403434YA (en) 2011-12-19 2014-09-26 Map Pharmaceuticals Inc Novel iso-ergoline derivatives
EP2793583A4 (en) 2011-12-21 2015-08-12 Map Pharmaceuticals Inc NOVEL NEUROMODULATORY CONNECTIONS
US9012640B2 (en) 2012-06-22 2015-04-21 Map Pharmaceuticals, Inc. Cabergoline derivatives
BR112017015487A2 (pt) 2015-01-20 2018-01-30 Xoc Pharmaceuticals Inc Composto; composição; método de tratamento e/ou prevenção de enxaqueca, als, doença de alzheimer, doença de parkinson, distúrbios extrapirimidais, depressão, náusea, êmese, síndrome das pernas inquietas, insônia, agressão, doença de huntington, doença cardiopulmonar, fibrogênese, hipertensão arterial pulmonar, ansiedade, dependências a drogas, distonia, parassonia ou hiperlactinemia em um indivíduo; métodos de agonização dos receptores d2, 5-ht1d, 5-ht1a e 5-ht2c, em um indivíduo; método de antagonização do receptor d3 em um indivíduo; métodos de agonização seletiva dos receptores 5 -ht1d, e 5-ht2c, método de fornecimento de atividade de antagonista funcional no receptor 5 -ht2b ou no receptor 5-ht7, ou em ambos, em um indivíduo; método de fornecimento de atividade de antagonista funcional nos receptores adrenérgicos em um indivíduo
BR112019025420A2 (pt) 2017-06-01 2020-06-16 Xoc Pharmaceuticals, Inc. Compostos policíclicos e usos destes

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2533699A (en) * 1950-12-12 Amines containing the king system
US2673850A (en) * 1951-07-28 1954-03-30 Sandoz Ag Piperazides of the lysergic acid series
US2946796A (en) * 1958-10-15 1960-07-26 Grace W R & Co Salts of ergot alkaloids
CH475252A (de) * 1966-02-08 1969-07-15 Sandoz Ag Verfahren zur Herstellung neuer Lysergsäure-Derivate
SE396753B (sv) * 1970-05-18 1977-10-03 Richter Gedeon Vegyeszet Analogiforfarande for framstellning av en forening tillhorande dihydrolysergsyraserien
US3901893A (en) * 1970-05-18 1975-08-26 Richter Gedeon Vegyeszet New dihydro-lysergic acid derivative
IL41409A (en) * 1972-02-04 1977-04-29 Richter Gedeon Vegyeszet Lysergic acid amides and process for their preparation

Also Published As

Publication number Publication date
NL7506276A (nl) 1975-12-02
ATA386375A (de) 1978-03-15
IL47361A0 (en) 1975-07-28
BG27374A3 (en) 1979-10-12
DD121639A5 (cs) 1976-08-12
DK143801C (da) 1982-03-22
FI61897B (fi) 1982-06-30
SE7505974L (sv) 1975-12-01
FR2272671B1 (cs) 1978-10-06
FI61897C (fi) 1982-10-11
GB1474337A (en) 1977-05-25
JPS5218718B2 (cs) 1977-05-24
CA1051878A (en) 1979-04-03
DK143801B (da) 1981-10-12
ES437994A1 (es) 1977-01-16
FR2272671A1 (cs) 1975-12-26
PL98944B1 (pl) 1978-05-31
HU169073B (cs) 1976-09-28
AU8142575A (en) 1976-11-25
FI751537A (cs) 1975-11-29
SE419548B (sv) 1981-08-10
US4005089A (en) 1977-01-25
SU625612A3 (ru) 1978-09-25
IL47361A (en) 1979-11-30
AT346501B (de) 1978-11-10
BE829518A (fr) 1975-09-15
JPS516998A (cs) 1976-01-20
DK235175A (da) 1975-11-29
YU135575A (en) 1982-06-30
DE2523743A1 (de) 1975-12-18

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