DE2114021A1 - Suessstoffkombination - Google Patents
SuessstoffkombinationInfo
- Publication number
- DE2114021A1 DE2114021A1 DE19712114021 DE2114021A DE2114021A1 DE 2114021 A1 DE2114021 A1 DE 2114021A1 DE 19712114021 DE19712114021 DE 19712114021 DE 2114021 A DE2114021 A DE 2114021A DE 2114021 A1 DE2114021 A1 DE 2114021A1
- Authority
- DE
- Germany
- Prior art keywords
- saccharin
- dipeptide
- sweetener
- sweetener combination
- aspartyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000003765 sweetening agent Substances 0.000 title claims description 20
- 235000003599 food sweetener Nutrition 0.000 title claims description 19
- CVHZOJJKTDOEJC-UHFFFAOYSA-N saccharin Chemical compound C1=CC=C2C(=O)NS(=O)(=O)C2=C1 CVHZOJJKTDOEJC-UHFFFAOYSA-N 0.000 claims description 41
- 229940081974 saccharin Drugs 0.000 claims description 33
- 235000019204 saccharin Nutrition 0.000 claims description 33
- 239000000901 saccharin and its Na,K and Ca salt Substances 0.000 claims description 33
- 108010016626 Dipeptides Proteins 0.000 claims description 23
- 125000004432 carbon atom Chemical group C* 0.000 claims description 8
- 150000004702 methyl esters Chemical class 0.000 claims description 2
- 125000000896 monocarboxylic acid group Chemical group 0.000 claims description 2
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims description 2
- 206010013911 Dysgeusia Diseases 0.000 description 16
- -1 with pectin Chemical compound 0.000 description 12
- 235000019640 taste Nutrition 0.000 description 11
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 10
- FTLYMKDSHNWQKD-UHFFFAOYSA-N (2,4,5-trichlorophenyl)boronic acid Chemical compound OB(O)C1=CC(Cl)=C(Cl)C=C1Cl FTLYMKDSHNWQKD-UHFFFAOYSA-N 0.000 description 7
- 229940085605 saccharin sodium Drugs 0.000 description 7
- 239000000203 mixture Substances 0.000 description 6
- 229930006000 Sucrose Natural products 0.000 description 5
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 description 5
- 235000002639 sodium chloride Nutrition 0.000 description 5
- 239000005720 sucrose Substances 0.000 description 5
- 235000009508 confectionery Nutrition 0.000 description 4
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 description 3
- 239000007788 liquid Substances 0.000 description 3
- 239000000843 powder Substances 0.000 description 3
- 235000019605 sweet taste sensations Nutrition 0.000 description 3
- FBPFZTCFMRRESA-FSIIMWSLSA-N D-Glucitol Natural products OC[C@H](O)[C@H](O)[C@@H](O)[C@H](O)CO FBPFZTCFMRRESA-FSIIMWSLSA-N 0.000 description 2
- FBPFZTCFMRRESA-JGWLITMVSA-N D-glucitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-JGWLITMVSA-N 0.000 description 2
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 2
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 2
- 230000001419 dependent effect Effects 0.000 description 2
- 239000004615 ingredient Substances 0.000 description 2
- 150000003839 salts Chemical class 0.000 description 2
- 239000000600 sorbitol Substances 0.000 description 2
- 235000010356 sorbitol Nutrition 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- 239000006188 syrup Substances 0.000 description 2
- 235000020357 syrup Nutrition 0.000 description 2
- 230000000007 visual effect Effects 0.000 description 2
- MHOVDMRJKGTEEI-QWRGUYRKSA-N (3s)-3-amino-4-[[(2s)-3-cyclohexa-1,4-dien-1-yl-1-methoxy-1-oxopropan-2-yl]amino]-4-oxobutanoic acid Chemical compound OC(=O)C[C@H](N)C(=O)N[C@H](C(=O)OC)CC1=CCC=CC1 MHOVDMRJKGTEEI-QWRGUYRKSA-N 0.000 description 1
- OWEGMIWEEQEYGQ-UHFFFAOYSA-N 100676-05-9 Natural products OC1C(O)C(O)C(CO)OC1OCC1C(O)C(O)C(O)C(OC2C(OC(O)C(O)C2O)CO)O1 OWEGMIWEEQEYGQ-UHFFFAOYSA-N 0.000 description 1
- 125000000094 2-phenylethyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])* 0.000 description 1
- 125000006201 3-phenylpropyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])* 0.000 description 1
- 244000215068 Acacia senegal Species 0.000 description 1
- 206010063659 Aversion Diseases 0.000 description 1
- 241000196324 Embryophyta Species 0.000 description 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 1
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 1
- 229920000084 Gum arabic Polymers 0.000 description 1
- GVGLGOZIDCSQPN-PVHGPHFFSA-N Heroin Chemical compound O([C@H]1[C@H](C=C[C@H]23)OC(C)=O)C4=C5[C@@]12CCN(C)[C@@H]3CC5=CC=C4OC(C)=O GVGLGOZIDCSQPN-PVHGPHFFSA-N 0.000 description 1
- GUBGYTABKSRVRQ-PICCSMPSSA-N Maltose Natural products O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@@H]1O[C@@H]1[C@@H](CO)OC(O)[C@H](O)[C@H]1O GUBGYTABKSRVRQ-PICCSMPSSA-N 0.000 description 1
- CZMRCDWAGMRECN-UHFFFAOYSA-N Rohrzucker Natural products OCC1OC(CO)(OC2OC(CO)C(O)C(O)C2O)C(O)C1O CZMRCDWAGMRECN-UHFFFAOYSA-N 0.000 description 1
- 229920002472 Starch Polymers 0.000 description 1
- 238000006887 Ullmann reaction Methods 0.000 description 1
- 240000008042 Zea mays Species 0.000 description 1
- 235000005824 Zea mays ssp. parviglumis Nutrition 0.000 description 1
- 235000002017 Zea mays subsp mays Nutrition 0.000 description 1
- 239000000205 acacia gum Substances 0.000 description 1
- 235000010489 acacia gum Nutrition 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 239000000654 additive Substances 0.000 description 1
- 230000000996 additive effect Effects 0.000 description 1
- 229910052783 alkali metal Inorganic materials 0.000 description 1
- 150000001340 alkali metals Chemical class 0.000 description 1
- 229910052784 alkaline earth metal Inorganic materials 0.000 description 1
- 150000003863 ammonium salts Chemical class 0.000 description 1
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 description 1
- WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 description 1
- 235000019658 bitter taste Nutrition 0.000 description 1
- MKJXYGKVIBWPFZ-UHFFFAOYSA-L calcium lactate Chemical compound [Ca+2].CC(O)C([O-])=O.CC(O)C([O-])=O MKJXYGKVIBWPFZ-UHFFFAOYSA-L 0.000 description 1
- 239000001527 calcium lactate Substances 0.000 description 1
- 229960002401 calcium lactate Drugs 0.000 description 1
- 235000011086 calcium lactate Nutrition 0.000 description 1
- 239000000969 carrier Substances 0.000 description 1
- 235000015165 citric acid Nutrition 0.000 description 1
- 239000012141 concentrate Substances 0.000 description 1
- 235000008504 concentrate Nutrition 0.000 description 1
- 235000005822 corn Nutrition 0.000 description 1
- 239000000625 cyclamic acid and its Na and Ca salt Substances 0.000 description 1
- 125000001995 cyclobutyl group Chemical group [H]C1([H])C([H])([H])C([H])(*)C1([H])[H] 0.000 description 1
- 125000000582 cycloheptyl group Chemical group [H]C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])(*)C([H])([H])C1([H])[H] 0.000 description 1
- 125000000113 cyclohexyl group Chemical group [H]C1([H])C([H])([H])C([H])([H])C([H])(*)C([H])([H])C1([H])[H] 0.000 description 1
- HCAJEUSONLESMK-UHFFFAOYSA-N cyclohexylsulfamic acid Chemical compound OS(=O)(=O)NC1CCCCC1 HCAJEUSONLESMK-UHFFFAOYSA-N 0.000 description 1
- 125000001511 cyclopentyl group Chemical group [H]C1([H])C([H])([H])C([H])([H])C([H])(*)C1([H])[H] 0.000 description 1
- 125000001559 cyclopropyl group Chemical group [H]C1([H])C([H])([H])C1([H])* 0.000 description 1
- 239000008121 dextrose Substances 0.000 description 1
- 239000012153 distilled water Substances 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 description 1
- 239000000796 flavoring agent Substances 0.000 description 1
- 235000019634 flavors Nutrition 0.000 description 1
- 235000013305 food Nutrition 0.000 description 1
- 235000011187 glycerol Nutrition 0.000 description 1
- 210000002837 heart atrium Anatomy 0.000 description 1
- 125000000959 isobutyl group Chemical group [H]C([H])([H])C([H])(C([H])([H])[H])C([H])([H])* 0.000 description 1
- 125000001449 isopropyl group Chemical group [H]C([H])([H])C([H])(*)C([H])([H])[H] 0.000 description 1
- 235000015110 jellies Nutrition 0.000 description 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 description 1
- 125000001280 n-hexyl group Chemical group C(CCCCC)* 0.000 description 1
- 125000000740 n-pentyl group Chemical group [H]C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])* 0.000 description 1
- 125000004123 n-propyl group Chemical group [H]C([H])([H])C([H])([H])C([H])([H])* 0.000 description 1
- 125000001971 neopentyl group Chemical group [H]C([*])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H] 0.000 description 1
- 239000006072 paste Substances 0.000 description 1
- 239000001814 pectin Substances 0.000 description 1
- 235000010987 pectin Nutrition 0.000 description 1
- 229920001277 pectin Polymers 0.000 description 1
- 230000002085 persistent effect Effects 0.000 description 1
- 239000000575 pesticide Substances 0.000 description 1
- 239000000546 pharmaceutical excipient Substances 0.000 description 1
- 239000011780 sodium chloride Substances 0.000 description 1
- 235000014214 soft drink Nutrition 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 239000007921 spray Substances 0.000 description 1
- 235000019698 starch Nutrition 0.000 description 1
- 239000008107 starch Substances 0.000 description 1
- 235000021092 sugar substitutes Nutrition 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L27/00—Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
- A23L27/30—Artificial sweetening agents
- A23L27/31—Artificial sweetening agents containing amino acids, nucleotides, peptides or derivatives
- A23L27/32—Artificial sweetening agents containing amino acids, nucleotides, peptides or derivatives containing dipeptides or derivatives
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/801—Peptide sweetners
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Health & Medical Sciences (AREA)
- Nutrition Science (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Peptides Or Proteins (AREA)
- Seasonings (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US2268670A | 1970-03-25 | 1970-03-25 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE2114021A1 true DE2114021A1 (de) | 1971-10-07 |
Family
ID=21810906
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE19712114021 Pending DE2114021A1 (de) | 1970-03-25 | 1971-03-23 | Suessstoffkombination |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US3695898A (enExample) |
| CA (1) | CA930604A (enExample) |
| CH (1) | CH536602A (enExample) |
| DE (1) | DE2114021A1 (enExample) |
| FR (1) | FR2087842A5 (enExample) |
| GB (1) | GB1352167A (enExample) |
| HU (1) | HU164517B (enExample) |
| IT (1) | IT946199B (enExample) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3800046A (en) * | 1967-04-17 | 1974-03-26 | Searle & Co | Artificially sweetened consumable products |
| US4001455A (en) * | 1970-03-25 | 1977-01-04 | E. R. Squibb & Sons, Inc. | Sweetening compositions |
| US3853835A (en) * | 1970-11-12 | 1974-12-10 | Searle & Co | Alkyl esters of aspartyl aliphatic amino acid dipeptides |
| US4031258A (en) * | 1972-03-30 | 1977-06-21 | General Foods Corporation | Inorganic salts of dipeptide sweeteners |
| US4029701A (en) * | 1972-03-30 | 1977-06-14 | General Foods Corporation | Sweetening with hydrohalide salts of dipeptide sweeteners |
| US4017472A (en) * | 1973-03-05 | 1977-04-12 | G. D. Searle & Co. | Process for isolation of aspartyl dipeptide esters |
| CA1028197A (en) * | 1973-04-02 | 1978-03-21 | Jeffrey H. Berg | Concentrated liquid low calorie sweetener |
| US4059706A (en) * | 1974-03-07 | 1977-11-22 | General Foods Corporation | Spray-dried L-aspartic acid derivatives |
| US4517214A (en) * | 1976-04-05 | 1985-05-14 | General Foods Corporation | Sweetening composition and method |
| US4412984A (en) * | 1977-04-26 | 1983-11-01 | Talres Development (N.A.) N.V. | Flavor potentiated oral compositions containing thaumatin or monellin |
| GB8403611D0 (en) * | 1984-02-10 | 1984-03-14 | Tate & Lyle Plc | Sweetener |
| US4738854A (en) * | 1984-12-04 | 1988-04-19 | Nabisco Brands, Inc. | Comestible containing moisture and shelf storage stabilized L-aspartic acid derivative |
| US4753806A (en) * | 1985-03-29 | 1988-06-28 | Nabisco Brands, Inc. | Flexible sugarless chewing gum |
| US4774094A (en) * | 1985-03-29 | 1988-09-27 | Nabisco Brands, Inc. | Stabilized APM in comestibles |
| US4800095A (en) * | 1985-03-29 | 1989-01-24 | Nabisco Brands, Inc. | Stabilized APM in comestibles |
| US4634792A (en) * | 1985-05-06 | 1987-01-06 | General Foods Corporation | L-aminodicarboxylic acid aminoalkenoic acid ester amides |
| US4622232A (en) * | 1985-05-06 | 1986-11-11 | General Foods Corporation | L-aminodicarboxylic acid alkanes |
| US4701552A (en) * | 1985-05-06 | 1987-10-20 | General Foods Corporation | L-aminodicarboxylic acid alkanes |
| US4603012A (en) * | 1985-05-06 | 1986-07-29 | General Foods Corporation | L-aminodicarboxylic acid alkanes |
| US5013716A (en) * | 1988-10-28 | 1991-05-07 | Warner-Lambert Company | Unpleasant taste masking compositions and methods for preparing same |
| US5126158A (en) * | 1990-08-07 | 1992-06-30 | Pepsico Inc. | Beverage compositions comprising a dipetide sweetener, saccharin salt and hydrocolloidal polysaccharide |
| DE69111050T2 (de) * | 1991-02-26 | 1995-11-23 | Zoster Sa | Verwendung von Neohesperidin-Dihydrochalcon zur Verstärkung des Körpers und des Mundgefühls von Nahrungsmitteln und Getränken. |
| AU643557B2 (en) * | 1991-09-09 | 1993-11-18 | Pepsico, Inc. | Novel beverage compositions comprising a dipeptide sweetener, saccharin salt and hydrocolloidal polysaccharide |
-
1970
- 1970-03-25 US US22686A patent/US3695898A/en not_active Expired - Lifetime
-
1971
- 1971-03-15 CA CA107718A patent/CA930604A/en not_active Expired
- 1971-03-23 DE DE19712114021 patent/DE2114021A1/de active Pending
- 1971-03-24 IT IT49293/71A patent/IT946199B/it active
- 1971-03-24 HU HUSU606A patent/HU164517B/hu unknown
- 1971-03-24 CH CH429971A patent/CH536602A/fr not_active IP Right Cessation
- 1971-03-25 FR FR7110663A patent/FR2087842A5/fr not_active Expired
- 1971-04-19 GB GB2486271*A patent/GB1352167A/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| GB1352167A (en) | 1974-05-08 |
| IT946199B (it) | 1973-05-21 |
| CA930604A (en) | 1973-07-24 |
| HU164517B (enExample) | 1974-02-28 |
| US3695898A (en) | 1972-10-03 |
| FR2087842A5 (enExample) | 1971-12-31 |
| CH536602A (fr) | 1973-05-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| OHW | Rejection |