DE2106038C3 - 2-Imidazolin-2-ylamino-benzo [b] thiophene und diese enthaltende pharmazeutische Präparate - Google Patents

2-Imidazolin-2-ylamino-benzo [b] thiophene und diese enthaltende pharmazeutische Präparate

Info

Publication number
DE2106038C3
DE2106038C3 DE2106038A DE2106038A DE2106038C3 DE 2106038 C3 DE2106038 C3 DE 2106038C3 DE 2106038 A DE2106038 A DE 2106038A DE 2106038 A DE2106038 A DE 2106038A DE 2106038 C3 DE2106038 C3 DE 2106038C3
Authority
DE
Germany
Prior art keywords
mol
ylamino
imidazolin
thiophene
solution
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE2106038A
Other languages
German (de)
English (en)
Other versions
DE2106038B2 (de
DE2106038A1 (de
Inventor
Hans-Juergen Ernst Old Lyme Hess
Roger Peter Waterford Nelson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Inc
Original Assignee
Pfizer Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Inc filed Critical Pfizer Inc
Publication of DE2106038A1 publication Critical patent/DE2106038A1/de
Publication of DE2106038B2 publication Critical patent/DE2106038B2/de
Application granted granted Critical
Publication of DE2106038C3 publication Critical patent/DE2106038C3/de
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/62—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/62—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • C07D333/66—Nitrogen atoms not forming part of a nitro radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/62—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • C07D333/68—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D333/70—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 2
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
DE2106038A 1970-03-02 1971-02-09 2-Imidazolin-2-ylamino-benzo [b] thiophene und diese enthaltende pharmazeutische Präparate Expired DE2106038C3 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US1586470A 1970-03-02 1970-03-02
US20386371A 1971-12-01 1971-12-01
US00324091A US3808335A (en) 1970-03-02 1973-01-16 (2-imidazolin-2-ylamino)substituted benzo(b)thiophenes for treating hypertension

Publications (3)

Publication Number Publication Date
DE2106038A1 DE2106038A1 (de) 1971-09-30
DE2106038B2 DE2106038B2 (de) 1979-09-27
DE2106038C3 true DE2106038C3 (de) 1980-06-19

Family

ID=27360436

Family Applications (1)

Application Number Title Priority Date Filing Date
DE2106038A Expired DE2106038C3 (de) 1970-03-02 1971-02-09 2-Imidazolin-2-ylamino-benzo [b] thiophene und diese enthaltende pharmazeutische Präparate

Country Status (5)

Country Link
US (2) US3740417A (cg-RX-API-DMAC10.html)
BE (1) BE762726A (cg-RX-API-DMAC10.html)
DE (1) DE2106038C3 (cg-RX-API-DMAC10.html)
FR (1) FR2085659B1 (cg-RX-API-DMAC10.html)
GB (1) GB1282535A (cg-RX-API-DMAC10.html)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH632268A5 (de) * 1977-01-14 1982-09-30 Sandoz Ag Verfahren zur herstellung von neuen heterocyclylaminoderivaten.
DE69118070T2 (de) * 1990-09-21 1996-11-21 Sumitomo Chemical Co Benzofuranyl- und Benzothiophenyl-substituierte Uracilderivate, ihre Herstellung und ihre Verwendung als Herbizide
GB9127050D0 (en) * 1991-12-20 1992-02-19 Orion Yhtymae Oy Substituted imidazole derivatives and their preparation and use
US5677321A (en) * 1996-02-29 1997-10-14 Synaptic Pharmaceutical Corporation 5- and 6-(2-imidazolin-2-ylamino) and -(2-thiazolin-2-ylamino)-benzothiazoles as alpha-2 adrenergic ligands
GB2361425B (en) * 2000-04-17 2004-03-31 Sorex Ltd Rodenticidal thiourea compounds
DE102020109429A1 (de) 2020-04-03 2021-10-07 Arntz Beteiligungs Gmbh & Co. Kg Antriebsriemen, insbesondere Zahnriemen, mit verbesserten Eigenschaften und Verfahren zur Herstellung hiervon

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1614A (cg-RX-API-DMAC10.html) * 1903-02-25

Also Published As

Publication number Publication date
BE762726A (fr) 1971-08-10
FR2085659B1 (cg-RX-API-DMAC10.html) 1974-08-30
US3740417A (en) 1973-06-19
US3808335A (en) 1974-04-30
DE2106038B2 (de) 1979-09-27
DE2106038A1 (de) 1971-09-30
GB1282535A (en) 1972-07-19
FR2085659A1 (cg-RX-API-DMAC10.html) 1971-12-31

Similar Documents

Publication Publication Date Title
DE1695556C3 (de) 3-Alkyl-1,2,3,4,4a,9-hexahydropyrazino[1,2-f]morphanthridinderivate
EP0148440B1 (de) 1,3,4,5-Tetrahydrobenz[c,d]indole, ein Verfahren zu ihrer Herstellung und ihre Verwendung
DE69108913T2 (de) 4-alkylimidazolderivate.
DE2461802C2 (de) Pyrazincarboxamidderivate
DE2635516B2 (de) Neue Derivate des Thiazole [3,4-b] isochinoline, ihre Herstellung und die sie enthaltenden Zusammensetzungen
EP0105210B1 (de) Isochinolinderivate, Verfahren zu ihrer Herstellung, pharmazeutische Präparate auf Basis dieser Verbindungen und ihre Verwendung
DE2106038C3 (de) 2-Imidazolin-2-ylamino-benzo [b] thiophene und diese enthaltende pharmazeutische Präparate
DE2351411C2 (de) (1-Oxo-2,3-hydrocarbylen-6,7-dichlor-5- indanyloxy)-essigsäuren, Verfahren zu ihrer Herstellung und sie enthaltende pharmazeutische Mittel
DE2512109A1 (de) Hexahydro-gamma-carbolinderivate, deren salze, verfahren zu ihrer herstellung und arzneipraeparate
DE2523103A1 (de) Neue propargyl-2-phenylamino-imidazoline-(2), deren saeureadditionssalze, diese enthaltende arzneimittel und verfahren zur herstellung derselben
EP0155903B1 (de) Indolophenanthridine, ihre Herstellung und Verwendung
DE3877124T2 (de) Imidazol-derivate, verfahren zu deren herstellung und deren anwendung als alpha-2-adrenoceptor-antagonisten.
DE2258318A1 (de) Neue organische verbindungen und verfahren zu deren herstellung
DE2535599C2 (de) Substituierte Zimtsäureamide, Verfahren zu ihrer Herstellung und pharmazeutische Zubereitungen, welche diese Verbindungen enthalten
EP0018360A1 (de) N-(5-Methoxybentofuran-2-ylcarbonyl)-N'-benzylpiperazin und Verfahren zu dessen Herstellung.
AT391316B (de) Neue thienyloxy-alkylamin-derivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
CH616935A5 (en) Process for the preparation of chromone derivatives
DE2456098C3 (de) Xanthen- und Thioxanthen-Derivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
DE2731662A1 (de) 5-(2-furoyl)-, 5-(2-thenoyl)-, 5-(3-furoyl)- und 5-(3-thenoyl)-1,2- dihydro-3h-pyrrolo- eckige klammer auf 1,2-a eckige klammer zu -pyrrol-1-carbonsaeurederivate und verfahren zur herstellung derselben
DE2359359B2 (de) Fluor-substituierte thioxanthene, verfahren zu ihrer herstellung sowie diese enthaltende neuroleptische mittel
CH579565A5 (en) Imidazolin-2-ylamino-2,1,3-benzothiadiazoles prodn. - by cyclising corresp. beta aminoethyl (thio) ureas, active against muscle tremors and rigor
DE2233088A1 (de) Benzomorphanderivate
EP0113911B1 (de) Pyrido-triazolochinazoline, ihre Herstellung und Verwendung
DE1445438C (cg-RX-API-DMAC10.html)
DE1963205A1 (de) Benzo[b]benzofurano[2,3-e]oxepin-Derivate

Legal Events

Date Code Title Description
C3 Grant after two publication steps (3rd publication)
8339 Ceased/non-payment of the annual fee