DE2065384C3 - Säureadditionssalze der Orthophosphorsäure und Bernsteinsäure mit 3-Methylflavon-8-carbonsäure-beta-piperidinoäthylester. Ausscheidung aus: 2059296 - Google Patents

Säureadditionssalze der Orthophosphorsäure und Bernsteinsäure mit 3-Methylflavon-8-carbonsäure-beta-piperidinoäthylester. Ausscheidung aus: 2059296

Info

Publication number
DE2065384C3
DE2065384C3 DE2065384*A DE2065384A DE2065384C3 DE 2065384 C3 DE2065384 C3 DE 2065384C3 DE 2065384 A DE2065384 A DE 2065384A DE 2065384 C3 DE2065384 C3 DE 2065384C3
Authority
DE
Germany
Prior art keywords
acid
methylflavone
addition salts
eliminated
beta
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE2065384*A
Other languages
English (en)
Other versions
DE2065384B2 (de
DE2065384A1 (de
Inventor
Enrico Dr. Mailand Sianesi (Italien)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Recordati Sa Chemical And Pharmaceutical Co Lugano (schweiz)
Original Assignee
Recordati Sa Chemical And Pharmaceutical Co Lugano (schweiz)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Recordati Sa Chemical And Pharmaceutical Co Lugano (schweiz) filed Critical Recordati Sa Chemical And Pharmaceutical Co Lugano (schweiz)
Publication of DE2065384A1 publication Critical patent/DE2065384A1/de
Publication of DE2065384B2 publication Critical patent/DE2065384B2/de
Application granted granted Critical
Publication of DE2065384C3 publication Critical patent/DE2065384C3/de
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
    • C07D311/26—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3
    • C07D311/28—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 2 only
    • C07D311/30—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 2 only not hydrogenated in the hetero ring, e.g. flavones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/16—Preparation of carboxylic acids or their salts, halides or anhydrides by oxidation
    • C07C51/295—Preparation of carboxylic acids or their salts, halides or anhydrides by oxidation with inorganic bases, e.g. by alkali fusion
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C65/00—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C65/32—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing keto groups
    • C07C65/40—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing keto groups containing singly bound oxygen-containing groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Inorganic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)

Description

2 G65

Claims (1)

  1. Patentanspruch:
    Säureadditionssalze der Orthophosphorsäure und Bernsteinsäure mit S-Methylflavon-S-carbonsäure-yS-piperidinoäthylester.
    Ihre Herstellung wird an Hand der folgenden Beispiele näher erläutert
    Beispiel 1
    3-Methylflavon-8-carbonsäure-/?-piperidinoäthylester-sucdnat
DE2065384*A 1970-08-01 1970-10-19 Säureadditionssalze der Orthophosphorsäure und Bernsteinsäure mit 3-Methylflavon-8-carbonsäure-beta-piperidinoäthylester. Ausscheidung aus: 2059296 Expired DE2065384C3 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT2819070 1970-08-01

Publications (3)

Publication Number Publication Date
DE2065384A1 DE2065384A1 (de) 1973-06-14
DE2065384B2 DE2065384B2 (de) 1974-04-18
DE2065384C3 true DE2065384C3 (de) 1974-11-14

Family

ID=11223109

Family Applications (2)

Application Number Title Priority Date Filing Date
DE2051269A Expired DE2051269C3 (de) 1970-08-01 1970-10-19 Verfahren zur Herstellung von 3-Propionylsalicylsäure
DE2065384*A Expired DE2065384C3 (de) 1970-08-01 1970-10-19 Säureadditionssalze der Orthophosphorsäure und Bernsteinsäure mit 3-Methylflavon-8-carbonsäure-beta-piperidinoäthylester. Ausscheidung aus: 2059296

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DE2051269A Expired DE2051269C3 (de) 1970-08-01 1970-10-19 Verfahren zur Herstellung von 3-Propionylsalicylsäure

Country Status (21)

Country Link
US (1) US3770802A (de)
JP (1) JPS514983B1 (de)
AT (2) AT311343B (de)
BE (1) BE757821A (de)
CA (1) CA932737A (de)
CH (1) CH517065A (de)
DE (2) DE2051269C3 (de)
DK (2) DK138639B (de)
ES (1) ES384635A1 (de)
FI (1) FI55828C (de)
FR (1) FR2109480A5 (de)
GB (2) GB1343119A (de)
IE (1) IE35304B1 (de)
IL (1) IL35797A (de)
NL (1) NL7015350A (de)
NO (1) NO134742C (de)
PL (1) PL81054B1 (de)
SE (2) SE368002B (de)
SU (1) SU383273A3 (de)
YU (3) YU35752B (de)
ZA (1) ZA707493B (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1499323A (en) * 1974-03-22 1978-02-01 Fisons Ltd 6-substituted chromones and chromanones
US3993669A (en) * 1974-06-05 1976-11-23 Syntex (U.S.A.) Inc. Mono- and disubstituted 1.4-benzopyrone-6-carboxylic acids and derivatives thereof
IT1051445B (it) 1975-07-16 1981-04-21 Recordati Chem Pharm Derivati dell.acido benzoico terapeuticamente attivi e procedimento per prepararli
FR2516922A1 (fr) * 1981-11-25 1983-05-27 Lipha Acides (oxo-4-4h-(1)-benzopyran-8-yl) alcanoiques, sels et derives, preparation et medicament les contenant
JPS58225083A (ja) * 1982-06-23 1983-12-27 Nippon Shinyaku Co Ltd メチルフラボン誘導体
JPS5967281A (ja) * 1982-09-30 1984-04-16 Yamamoto Kagaku Kogyo Kk ３−メチルフラボン−８−カルボン酸誘導体及びその製造法
JPS5967242A (ja) * 1982-09-30 1984-04-16 Yamamoto Kagaku Kogyo Kk ３−プロピオニルサリチル酸誘導体及びその製造法
US4499295A (en) * 1983-05-09 1985-02-12 G. D. Searle & Co. Protease inhibitors
US5116954A (en) * 1988-04-06 1992-05-26 Lipha, Lyonnaise Industrielle Pharmaceutique Pharmaceutically useful flavonoic compounds containing at least one substituent on the benzopyranone ring moiety
CN114736183B (zh) * 2022-04-14 2023-10-17 迪嘉药业集团股份有限公司 一种3-甲基黄酮-8-羧酸的制备方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL94071C (de) * 1954-04-20
US2921070A (en) * 1957-11-05 1960-01-12 Recordati Lab Farmacologico S Basic esters of 3-methylflavone-8-carboxylic acid
FR1441427A (fr) * 1963-10-10 1966-06-10 Recordati S P A Procédé de préparation de l'acide 3-méthylflavone-8-carboxylique et de ses esters basiques

Also Published As

Publication number Publication date
DE2065384B2 (de) 1974-04-18
DK138639C (de) 1979-03-12
IL35797A (en) 1974-01-14
AT311343B (de) 1973-11-12
GB1343119A (en) 1974-01-09
SE368002B (de) 1974-06-17
ZA707493B (en) 1971-08-25
IE35304L (en) 1972-02-01
DE2051269A1 (de) 1972-02-03
AT302280B (de) 1972-10-10
CA932737A (en) 1973-08-28
IE35304B1 (en) 1976-01-07
NL7015350A (de) 1972-02-03
IL35797A0 (en) 1971-02-25
SE388199B (sv) 1976-09-27
NO134742B (de) 1976-08-30
DK128562B (da) 1974-05-27
CH517065A (fr) 1971-12-31
DE2059296A1 (de) 1972-02-10
US3770802A (en) 1973-11-06
YU269070A (en) 1980-10-31
DE2059296B2 (de) 1977-04-14
YU36018B (en) 1981-11-13
GB1343118A (en) 1974-01-09
ES384635A1 (es) 1973-01-16
DE2051269C3 (de) 1975-03-27
PL81054B1 (de) 1975-08-30
YU35751B (en) 1981-06-30
SU383273A3 (de) 1973-05-25
DK138639B (da) 1978-10-09
FR2109480A5 (de) 1972-05-26
DE2065384A1 (de) 1973-06-14
JPS514983B1 (de) 1976-02-16
DE2051269B2 (de) 1974-08-01
BE757821A (fr) 1971-04-01
NO134742C (de) 1976-12-08
FI55828B (fi) 1979-06-29
YU35752B (en) 1981-06-30
YU6279A (en) 1981-02-28
FI55828C (fi) 1979-10-10

Similar Documents

Publication Publication Date Title
DE2065384C3 (de) Säureadditionssalze der Orthophosphorsäure und Bernsteinsäure mit 3-Methylflavon-8-carbonsäure-beta-piperidinoäthylester. Ausscheidung aus: 2059296
AT310146B (de) Verfahren zur Herstellung von neuen N,N'-Bis-(β-hydroxyaryläthyl)-diaminoalkanen und deren Säureadditionssalzen
AT296981B (de) Verfahren zur Herstellung von neuen 1,2,3,11b-Tetrahydropyrido[3,4,5:m,n]thioxanthenen und deren Säureadditionssalzen
SE385895B (sv) Forfarande for framstellning av mononitratestrar av 1,4:3,6-dianhydro-
TR18053A (tr) O-etil-s, n-propil-o-/piridaz- (3)-on-6-il/tiono-fiolfosforik asid esterler, bunlarin en hazirlanmasina mahsus usul ve bunlarin en sektisidler ve akarisidler olarak kullanilmalari
AT294095B (de) Verfahren zur Herstellung von neuen 6,7-Diacyloxytetrahydroisochinolin-Verbindungen und von deren Säureadditionssalzen
CA982593A (en) Substituted 2-arylamino-imidazolines-(2) the acid addition salts and processes for the production thereof
AT313874B (de) Verfahren zur Herstellung von neuen 2-Hydroxy- oder 2,3-Dihydroxy-5-alkoxycarbonyl-benzyloxyaminen und deren Säureadditionssalzen
AT285564B (de) Herstellung von Lactonen mit 6 bis 13 Ringgliedern sowie Isobuttersäure
AT283317B (de) Verfahren zur herstellung von neuen, gemischt substituierten 1-phenoxy-3-alkylaminopropanolen-(2) und deren saeureadditionssalzen
ES430900A1 (es) Un procedimiento para la preparacion de acidos (1-oxo-2-arilo tienil-2-sustituido-5-indaniloxi (o tio) alcanoicos y derivados de los mismos..
AT315141B (de) Verfahren zur Herstellung von neuen basischen 2,2-Diphenylcyclopropancarbonsäureestern und von deren Säureadditionssalzen
AT302314B (de) Verfahren zur Herstellung von neuen 7-Acyl-1,2,4,5-tetrahydro-(3H)-3-benzazepinen und deren Säureadditionssalzen
AT311349B (de) Verfahren zur Herstellung von neuen 1,2,3,6,-Tetrahydro-4-pyridylmethyl-carbonsäureestern, deren Säureadditionssalzen und quaternären Ammoniumverbindungen
AT311973B (de) Verfahren zur Herstellung von neuen 1,2,3,4-Tetrahydroisochinolin-Verbindungen sowie von deren Säureadditionssalzen
KR790000084B1 (en) Process for preparation of antibiotics of cephalosphorin and penicillin series
AT321918B (de) Verfahren zur herstellung von 4,4-diaryl-piperidinen und deren säureadditionssalzen
AT325624B (de) Verfahren zur herstellung von neuen dibenz (b,f) (1,4)oxazepinen und ihren saureadditionssalzen
ATA928373A (de) Verfahren zur herstellung von neuen dibenz (b,f) (1,4)oxazepinen und ihren saeureadditionssalzen
AT326666B (de) Verfahren zur herstellung von neuen 1,4-diazacycloalkanderivaten und deren säureadditionssalzen
SE382981B (sv) Forfarande for framstellning av hemiestrar av dikarboxylsyror i form av 1,2-difenyl-4-n-butyl-4-hydroximetyl-3,5-dioxipyrazolidin
IT1046966B (it) Procedimento per la produzione i tiadiazolil 6 acilossitetraidro pirimidinoni prodotto ottenuto e composizioni diserbanti che contengono il detto prodotto come componente attivo
AT301564B (de) Verfahren zur Herstellung von neuen 4-Morpholino-thieno[3,2-d]pyrimidinen und deren Säureadditionssalzen
AT301563B (de) Verfahren zur Herstellung von neuen 4-Morpholino-thieno[3,2-d]pyrimidinen und deren Säureadditionssalzen
BE777690A (fr) Derives de l'acide cinnamique utilisables notamment comme insecticides

Legal Events

Date Code Title Description
C3 Grant after two publication steps (3rd publication)
E77 Valid patent as to the heymanns-index 1977