DE2034784A1 - Adenosin 5 carbonsäureester - Google Patents
Adenosin 5 carbonsäureesterInfo
- Publication number
- DE2034784A1 DE2034784A1 DE19702034784 DE2034784A DE2034784A1 DE 2034784 A1 DE2034784 A1 DE 2034784A1 DE 19702034784 DE19702034784 DE 19702034784 DE 2034784 A DE2034784 A DE 2034784A DE 2034784 A1 DE2034784 A1 DE 2034784A1
- Authority
- DE
- Germany
- Prior art keywords
- adenosine
- carboxylic acid
- general formula
- acid ester
- group
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- STKYXVXUUPIMSU-UHFFFAOYSA-N (1-acetylindazol-5-yl) acetate Chemical compound CC(=O)OC1=CC=C2N(C(C)=O)N=CC2=C1 STKYXVXUUPIMSU-UHFFFAOYSA-N 0.000 title 1
- 239000002253 acid Substances 0.000 claims description 6
- 150000001875 compounds Chemical class 0.000 claims description 5
- MWEQTWJABOLLOS-UHFFFAOYSA-L disodium;[[[5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-oxidophosphoryl] hydrogen phosphate;trihydrate Chemical compound O.O.O.[Na+].[Na+].C1=NC=2C(N)=NC=NC=2N1C1OC(COP(O)(=O)OP([O-])(=O)OP(O)([O-])=O)C(O)C1O MWEQTWJABOLLOS-UHFFFAOYSA-L 0.000 claims description 5
- 150000002148 esters Chemical class 0.000 claims description 5
- 238000000034 method Methods 0.000 claims description 5
- 150000007513 acids Chemical class 0.000 claims description 3
- 125000001931 aliphatic group Chemical group 0.000 claims description 3
- 125000004435 hydrogen atom Chemical group [H]* 0.000 claims description 3
- 229910052500 inorganic mineral Inorganic materials 0.000 claims description 3
- 238000004519 manufacturing process Methods 0.000 claims description 3
- 239000011707 mineral Substances 0.000 claims description 3
- 125000002947 alkylene group Chemical group 0.000 claims description 2
- OIRDTQYFTABQOQ-KQYNXXCUSA-N adenosine Chemical compound C1=NC=2C(N)=NC=NC=2N1[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O OIRDTQYFTABQOQ-KQYNXXCUSA-N 0.000 description 8
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 description 6
- ZMANZCXQSJIPKH-UHFFFAOYSA-N Triethylamine Chemical compound CCN(CC)CC ZMANZCXQSJIPKH-UHFFFAOYSA-N 0.000 description 6
- -1 adenosine-5'-carboxylic acid methyl ester Chemical class 0.000 description 5
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 5
- 239000002126 C01EB10 - Adenosine Substances 0.000 description 4
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 4
- QAOWNCQODCNURD-UHFFFAOYSA-N Sulfuric acid Chemical compound OS(O)(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-N 0.000 description 4
- 229960005305 adenosine Drugs 0.000 description 4
- IBYWUFHJUDTSOC-SOVPELCUSA-N 9-riburonosyladenine Chemical compound C1=NC=2C(N)=NC=NC=2N1[C@@H]1O[C@H](C(O)=O)[C@@H](O)[C@H]1O IBYWUFHJUDTSOC-SOVPELCUSA-N 0.000 description 3
- WVDDGKGOMKODPV-UHFFFAOYSA-N Benzyl alcohol Chemical compound OCC1=CC=CC=C1 WVDDGKGOMKODPV-UHFFFAOYSA-N 0.000 description 3
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 description 3
- 238000006243 chemical reaction Methods 0.000 description 3
- 238000002844 melting Methods 0.000 description 3
- 230000008018 melting Effects 0.000 description 3
- LRHPLDYGYMQRHN-UHFFFAOYSA-N N-Butanol Chemical compound CCCCO LRHPLDYGYMQRHN-UHFFFAOYSA-N 0.000 description 2
- 230000032050 esterification Effects 0.000 description 2
- 238000005886 esterification reaction Methods 0.000 description 2
- 239000013067 intermediate product Substances 0.000 description 2
- 239000000047 product Substances 0.000 description 2
- 239000011541 reaction mixture Substances 0.000 description 2
- KWTSXDURSIMDCE-QMMMGPOBSA-N (S)-amphetamine Chemical compound C[C@H](N)CC1=CC=CC=C1 KWTSXDURSIMDCE-QMMMGPOBSA-N 0.000 description 1
- 241000343232 Oia Species 0.000 description 1
- 125000000217 alkyl group Chemical group 0.000 description 1
- 150000001412 amines Chemical group 0.000 description 1
- 235000019445 benzyl alcohol Nutrition 0.000 description 1
- 150000001735 carboxylic acids Chemical class 0.000 description 1
- 230000003197 catalytic effect Effects 0.000 description 1
- 238000001816 cooling Methods 0.000 description 1
- 239000012043 crude product Substances 0.000 description 1
- 229960000632 dexamfetamine Drugs 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 239000000706 filtrate Substances 0.000 description 1
- JNONJXMVMJSMTC-UHFFFAOYSA-N hydron;triethylazanium;sulfate Chemical compound OS(O)(=O)=O.CCN(CC)CC JNONJXMVMJSMTC-UHFFFAOYSA-N 0.000 description 1
- 150000004702 methyl esters Chemical class 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 239000002904 solvent Chemical group 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/16—Purine radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Saccharide Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (18)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19702034784 DE2034784A1 (de) | 1970-07-14 | 1970-07-14 | Adenosin 5 carbonsäureester |
| ZA714479A ZA714479B (en) | 1970-07-14 | 1971-07-07 | New esters of adenosine-5'-carboxylic acid and the preparation thereof |
| ES393023A ES393023A1 (es) | 1970-07-14 | 1971-07-08 | Procedimiento para la preparacion de esteres de acidos ade-nosin-5'-carboxilicos. |
| SE7108838A SE378603B (enrdf_load_stackoverflow) | 1970-07-14 | 1971-07-08 | |
| GB1295229D GB1295229A (enrdf_load_stackoverflow) | 1970-07-14 | 1971-07-08 | |
| FI1962/71A FI55668C (fi) | 1970-07-14 | 1971-07-09 | Foerfarande foer framstaellning av adenosin-5'-karboxylsyraestrar |
| US05/161,338 US4224438A (en) | 1970-07-14 | 1971-07-09 | Adenosine-5'-carboxylic acid amides |
| CH1013071A CH556344A (de) | 1970-07-14 | 1971-07-09 | Verfahren zur herstellung von adenosin-5'-carbonsaeureestern. |
| IL37281A IL37281A (en) | 1970-07-14 | 1971-07-09 | Esters of adenosine-5'-carboxylic acid and processes for the preparation thereof |
| CA118,019A CA980342A (en) | 1970-07-14 | 1971-07-12 | Adenosine-5'-carboxylic acid esters and process for their preparation |
| NL7109609A NL7109609A (enrdf_load_stackoverflow) | 1970-07-14 | 1971-07-12 | |
| YU1832/71A YU34799B (en) | 1970-07-14 | 1971-07-12 | Process for preparing novel ester derivatives of adenosine-5-carboxylic acid |
| AT611471A AT306254B (de) | 1970-07-14 | 1971-07-13 | Verfahren zur Herstellung von neuen Adenosin-5'-carbonsäureestern |
| FR7125624A FR2101638A5 (enrdf_load_stackoverflow) | 1970-07-14 | 1971-07-13 | |
| HUBO1303A HU162215B (enrdf_load_stackoverflow) | 1970-07-14 | 1971-07-13 | |
| SU1682300A SU402217A1 (ru) | 1971-07-13 | Способ получения сложных эфиров аденозин-5'-карбоновой кислоты | |
| IE885/71A IE35536B1 (en) | 1970-07-14 | 1971-07-13 | Adenosine-5'-carboxylic acid esters |
| JP5238771A JPS5549080B1 (enrdf_load_stackoverflow) | 1970-07-14 | 1971-07-14 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19702034784 DE2034784A1 (de) | 1970-07-14 | 1970-07-14 | Adenosin 5 carbonsäureester |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE2034784A1 true DE2034784A1 (de) | 1972-01-20 |
Family
ID=5776674
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE19702034784 Pending DE2034784A1 (de) | 1970-07-14 | 1970-07-14 | Adenosin 5 carbonsäureester |
Country Status (16)
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2900334A1 (fr) * | 2006-04-28 | 2007-11-02 | Oreal | Procede de depigmentation de la peau |
-
1970
- 1970-07-14 DE DE19702034784 patent/DE2034784A1/de active Pending
-
1971
- 1971-07-07 ZA ZA714479A patent/ZA714479B/xx unknown
- 1971-07-08 GB GB1295229D patent/GB1295229A/en not_active Expired
- 1971-07-08 ES ES393023A patent/ES393023A1/es not_active Expired
- 1971-07-08 SE SE7108838A patent/SE378603B/xx unknown
- 1971-07-09 IL IL37281A patent/IL37281A/xx unknown
- 1971-07-09 FI FI1962/71A patent/FI55668C/fi active
- 1971-07-09 CH CH1013071A patent/CH556344A/xx not_active IP Right Cessation
- 1971-07-12 NL NL7109609A patent/NL7109609A/xx not_active Application Discontinuation
- 1971-07-12 CA CA118,019A patent/CA980342A/en not_active Expired
- 1971-07-12 YU YU1832/71A patent/YU34799B/xx unknown
- 1971-07-13 HU HUBO1303A patent/HU162215B/hu unknown
- 1971-07-13 IE IE885/71A patent/IE35536B1/xx unknown
- 1971-07-13 AT AT611471A patent/AT306254B/de not_active IP Right Cessation
- 1971-07-13 FR FR7125624A patent/FR2101638A5/fr not_active Expired
- 1971-07-14 JP JP5238771A patent/JPS5549080B1/ja active Pending
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2900334A1 (fr) * | 2006-04-28 | 2007-11-02 | Oreal | Procede de depigmentation de la peau |
| EP1878470A1 (fr) * | 2006-04-28 | 2008-01-16 | L'Oréal | Procédé de dépigmentation de la peau |
Also Published As
| Publication number | Publication date |
|---|---|
| FI55668B (fi) | 1979-05-31 |
| ZA714479B (en) | 1972-04-26 |
| SU402217A3 (enrdf_load_stackoverflow) | 1973-10-12 |
| CH556344A (de) | 1974-11-29 |
| FR2101638A5 (enrdf_load_stackoverflow) | 1972-03-31 |
| GB1295229A (enrdf_load_stackoverflow) | 1972-11-08 |
| HU162215B (enrdf_load_stackoverflow) | 1973-01-29 |
| AT306254B (de) | 1973-04-10 |
| CA980342A (en) | 1975-12-23 |
| ES393023A1 (es) | 1973-08-01 |
| IL37281A0 (en) | 1971-10-20 |
| YU183271A (en) | 1979-09-10 |
| SE378603B (enrdf_load_stackoverflow) | 1975-09-08 |
| YU34799B (en) | 1980-03-15 |
| IL37281A (en) | 1974-03-14 |
| IE35536L (en) | 1972-01-14 |
| FI55668C (fi) | 1979-09-10 |
| IE35536B1 (en) | 1976-03-18 |
| JPS5549080B1 (enrdf_load_stackoverflow) | 1980-12-10 |
| NL7109609A (enrdf_load_stackoverflow) | 1972-01-18 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| OHN | Withdrawal |