DE2031224A1 - Substituierte Salicylsauren und Ver fahren zu deren Herstellung - Google Patents

Substituierte Salicylsauren und Ver fahren zu deren Herstellung

Info

Publication number
DE2031224A1
DE2031224A1 DE19702031224 DE2031224A DE2031224A1 DE 2031224 A1 DE2031224 A1 DE 2031224A1 DE 19702031224 DE19702031224 DE 19702031224 DE 2031224 A DE2031224 A DE 2031224A DE 2031224 A1 DE2031224 A1 DE 2031224A1
Authority
DE
Germany
Prior art keywords
alkyl
radical
alkoxy
halogen
hydroxy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
DE19702031224
Other languages
German (de)
English (en)
Inventor
Tsung Ying Walford Gordon Lyn Witzel Bruce Edward Westfield Bugianesi Robert Louis Colonia N J Shen (V St A)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of DE2031224A1 publication Critical patent/DE2031224A1/de
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C65/00—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C65/32—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing keto groups
    • C07C65/40—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing keto groups containing singly bound oxygen-containing groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00—Sulfones; Sulfoxides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00—Ethers; Compounds having groups, groups or groups
    • C07C43/02—Ethers
    • C07C43/20—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring
    • C07C43/205—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring the aromatic ring being a non-condensed ring
    • C07C43/2055—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring the aromatic ring being a non-condensed ring containing more than one ether bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/45—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation
    • C07C45/46—Friedel-Crafts reactions
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/673—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by change of size of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
    • C07C49/82—Ketones containing a keto group bound to a six-membered aromatic ring containing hydroxy groups
    • C07C49/83—Ketones containing a keto group bound to a six-membered aromatic ring containing hydroxy groups polycyclic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C65/00—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C65/01—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing hydroxy or O-metal groups
    • C07C65/105—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing hydroxy or O-metal groups polycyclic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C65/00—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C65/01—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing hydroxy or O-metal groups
    • C07C65/19—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing hydroxy or O-metal groups having unsaturation outside the aromatic ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE19702031224 1969-06-25 1970-06-24 Substituierte Salicylsauren und Ver fahren zu deren Herstellung Pending DE2031224A1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US83660469A 1969-06-25 1969-06-25
US3032070A 1970-04-20 1970-04-20

Publications (1)

Publication Number Publication Date
DE2031224A1 true DE2031224A1 (de) 1971-01-07

Family

ID=26705907

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19702031224 Pending DE2031224A1 (de) 1969-06-25 1970-06-24 Substituierte Salicylsauren und Ver fahren zu deren Herstellung

Country Status (7)

Country Link
JP (1) JPS504653B1 (enExample)
CA (1) CA940146A (enExample)
CH (1) CH545265A (enExample)
DE (1) DE2031224A1 (enExample)
FR (1) FR2053011A1 (enExample)
GB (1) GB1293626A (enExample)
NL (1) NL7008627A (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0752421A1 (en) * 1995-07-07 1997-01-08 Zeneca Limited Ortho-substituted aromatic compounds, containing three (het)aryl moieties, their preparation and their use as prostaglandin E2-(PGE2)-antagonists

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3635311A1 (de) * 1986-10-17 1988-04-21 Bayer Ag Hydroxycarbonsaeurederivate, verfahren zu ihrer herstellung und ihre verwendung in druck- oder waermeempfindlichen aufzeichnungsmaterialien
DE3635742A1 (de) * 1986-10-21 1988-05-05 Bayer Ag Hydroxycarbonsaeurederivate und ihre verwendung in aufzeichnungsmaterialien
US5235064A (en) * 1987-01-12 1993-08-10 Eli Lilly And Company Leukotriene antagonists
US5171882A (en) * 1987-01-12 1992-12-15 Eli Lilly And Company Leukotriene antagonists
CA1320490C (en) * 1987-01-12 1993-07-20 Darrel M. Gapinski Anti-inflammatory agents
US4992576A (en) * 1987-01-12 1991-02-12 Eli Lilly And Company Intermediates for leukotriene antagonists
GB8925833D0 (en) * 1989-11-15 1990-01-04 Robertet Sa Derivatives of aromatic benzoates as inhibitors of esterase-producing micro-organisms
US4996230A (en) * 1990-02-16 1991-02-26 Eli Lilly And Company Leukotriene antagonists
GB9214120D0 (en) * 1991-07-25 1992-08-12 Ici Plc Therapeutic amides
GB9305295D0 (en) * 1993-03-15 1993-05-05 Zeneca Ltd Therapeutic compounds
GB9310095D0 (en) * 1993-05-17 1993-06-30 Zeneca Ltd Therapeutic compounds
FR2762839B1 (fr) * 1997-04-30 2001-05-11 Oreal Nouveaux derives de l'acide salicylique et leur utilisation dans une composition cosmetique et/ou dermatologique
BR9915090A (pt) * 1998-11-05 2001-10-30 Toyama Chemical Co Ltd Composto ou um sal do mesmo, peptìdeo ou um saldo mesmo, derivado de benzeno ou um sal domesmo, método para inibir ap-1, agente paraprevenir e tratar uma doença na qual participeuma sobre-expressão de ap-1 e uma doençaautoimune, e, inibidor de ap-1
CN119019226B (zh) * 2024-10-25 2025-01-07 山东第一医科大学(山东省医学科学院) 一种光引发苯甲醚脱甲基的方法

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0752421A1 (en) * 1995-07-07 1997-01-08 Zeneca Limited Ortho-substituted aromatic compounds, containing three (het)aryl moieties, their preparation and their use as prostaglandin E2-(PGE2)-antagonists

Also Published As

Publication number Publication date
CA940146A (en) 1974-01-15
NL7008627A (enExample) 1970-12-29
FR2053011A1 (enExample) 1971-04-16
GB1293626A (en) 1972-10-18
JPS504653B1 (enExample) 1975-02-22
CH545265A (de) 1973-12-15

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