DE2019341C3 - Einrichtung zur Simulierung von Strömungswirkungen in einer gerinnenden Flüssigkeit, insbesondere in Blut - Google Patents
Einrichtung zur Simulierung von Strömungswirkungen in einer gerinnenden Flüssigkeit, insbesondere in BlutInfo
- Publication number
- DE2019341C3 DE2019341C3 DE2019341A DE2019341A DE2019341C3 DE 2019341 C3 DE2019341 C3 DE 2019341C3 DE 2019341 A DE2019341 A DE 2019341A DE 2019341 A DE2019341 A DE 2019341A DE 2019341 C3 DE2019341 C3 DE 2019341C3
- Authority
- DE
- Germany
- Prior art keywords
- blood
- container
- orbital movement
- coagulation
- clot
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 230000000694 effects Effects 0.000 title claims description 27
- 210000004369 blood Anatomy 0.000 title claims description 20
- 239000008280 blood Substances 0.000 title claims description 20
- 239000007788 liquid Substances 0.000 title claims description 10
- 230000001112 coagulating effect Effects 0.000 title claims description 6
- 230000033001 locomotion Effects 0.000 claims description 38
- 230000005684 electric field Effects 0.000 claims description 2
- 238000000034 method Methods 0.000 description 21
- 238000005259 measurement Methods 0.000 description 20
- 230000008569 process Effects 0.000 description 18
- 230000015271 coagulation Effects 0.000 description 17
- 238000005345 coagulation Methods 0.000 description 17
- 102000009123 Fibrin Human genes 0.000 description 8
- 108010073385 Fibrin Proteins 0.000 description 8
- BWGVNKXGVNDBDI-UHFFFAOYSA-N Fibrin monomer Chemical compound CNC(=O)CNC(=O)CN BWGVNKXGVNDBDI-UHFFFAOYSA-N 0.000 description 8
- 210000001772 blood platelet Anatomy 0.000 description 8
- 229950003499 fibrin Drugs 0.000 description 8
- 210000002381 plasma Anatomy 0.000 description 8
- 230000035602 clotting Effects 0.000 description 6
- 238000012360 testing method Methods 0.000 description 6
- 239000000835 fiber Substances 0.000 description 5
- 206010053567 Coagulopathies Diseases 0.000 description 4
- 208000007536 Thrombosis Diseases 0.000 description 3
- 230000023555 blood coagulation Effects 0.000 description 3
- 238000000338 in vitro Methods 0.000 description 3
- 229910052751 metal Inorganic materials 0.000 description 3
- 239000002184 metal Substances 0.000 description 3
- 239000000758 substrate Substances 0.000 description 3
- 210000001015 abdomen Anatomy 0.000 description 2
- 230000015572 biosynthetic process Effects 0.000 description 2
- 230000017531 blood circulation Effects 0.000 description 2
- 210000004204 blood vessel Anatomy 0.000 description 2
- 230000015556 catabolic process Effects 0.000 description 2
- 230000008859 change Effects 0.000 description 2
- 238000004132 cross linking Methods 0.000 description 2
- 201000010099 disease Diseases 0.000 description 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 2
- 230000020764 fibrinolysis Effects 0.000 description 2
- 238000002347 injection Methods 0.000 description 2
- 239000007924 injection Substances 0.000 description 2
- 230000010349 pulsation Effects 0.000 description 2
- 238000000926 separation method Methods 0.000 description 2
- 238000004088 simulation Methods 0.000 description 2
- 238000007711 solidification Methods 0.000 description 2
- 230000008023 solidification Effects 0.000 description 2
- 210000003462 vein Anatomy 0.000 description 2
- 102000015081 Blood Coagulation Factors Human genes 0.000 description 1
- 108010039209 Blood Coagulation Factors Proteins 0.000 description 1
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 description 1
- VEXZGXHMUGYJMC-UHFFFAOYSA-M Chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 description 1
- 206010010356 Congenital anomaly Diseases 0.000 description 1
- 240000004808 Saccharomyces cerevisiae Species 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- 239000004480 active ingredient Substances 0.000 description 1
- 210000001367 artery Anatomy 0.000 description 1
- 210000000601 blood cell Anatomy 0.000 description 1
- 239000003114 blood coagulation factor Substances 0.000 description 1
- 229940019700 blood coagulation factors Drugs 0.000 description 1
- 238000009534 blood test Methods 0.000 description 1
- 229910052791 calcium Inorganic materials 0.000 description 1
- 239000011575 calcium Substances 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 238000006731 degradation reaction Methods 0.000 description 1
- 238000001514 detection method Methods 0.000 description 1
- 238000003745 diagnosis Methods 0.000 description 1
- 238000001727 in vivo Methods 0.000 description 1
- 238000002955 isolation Methods 0.000 description 1
- 238000011005 laboratory method Methods 0.000 description 1
- 238000011326 mechanical measurement Methods 0.000 description 1
- 230000007246 mechanism Effects 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000003287 optical effect Effects 0.000 description 1
- 230000002093 peripheral effect Effects 0.000 description 1
- 230000035790 physiological processes and functions Effects 0.000 description 1
- 239000002244 precipitate Substances 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 238000002791 soaking Methods 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 238000003756 stirring Methods 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 238000012546 transfer Methods 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/483—Physical analysis of biological material
- G01N33/487—Physical analysis of biological material of liquid biological material
- G01N33/49—Blood
- G01N33/4905—Determining clotting time of blood
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N11/00—Investigating flow properties of materials, e.g. viscosity, plasticity; Analysing materials by determining flow properties
- G01N11/10—Investigating flow properties of materials, e.g. viscosity, plasticity; Analysing materials by determining flow properties by moving a body within the material
- G01N11/16—Investigating flow properties of materials, e.g. viscosity, plasticity; Analysing materials by determining flow properties by moving a body within the material by measuring damping effect upon oscillatory body
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Physics & Mathematics (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Biochemistry (AREA)
- Hematology (AREA)
- Analytical Chemistry (AREA)
- Ecology (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Priority Applications (8)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE2019341A DE2019341C3 (de) | 1970-04-22 | 1970-04-22 | Einrichtung zur Simulierung von Strömungswirkungen in einer gerinnenden Flüssigkeit, insbesondere in Blut |
| NL7104868A NL7104868A (https=) | 1970-04-22 | 1971-04-13 | |
| FR7113166A FR2089651A5 (https=) | 1970-04-22 | 1971-04-14 | |
| US00134143A US3714815A (en) | 1970-04-22 | 1971-04-15 | Means for simulating the natural flow of blood |
| JP2534971A JPS5434360B1 (https=) | 1970-04-22 | 1971-04-21 | |
| GB1038571*[A GB1353481A (en) | 1970-04-22 | 1971-04-21 | Determination of coagulation characteristics of blood |
| CH580171A CH535957A (de) | 1970-04-22 | 1971-04-21 | Vorrichtung zur Bestimmung des Gerinnungsverhaltens von gerinnenden Flüssigkeiten |
| SE7105201A SE381342B (sv) | 1970-04-22 | 1971-04-21 | Anordning for bestemmande av elasticiteten hos levrande vetskor, serskilt blod |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE2019341A DE2019341C3 (de) | 1970-04-22 | 1970-04-22 | Einrichtung zur Simulierung von Strömungswirkungen in einer gerinnenden Flüssigkeit, insbesondere in Blut |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| DE2019341A1 DE2019341A1 (de) | 1971-11-04 |
| DE2019341B2 DE2019341B2 (de) | 1979-04-19 |
| DE2019341C3 true DE2019341C3 (de) | 1979-12-20 |
Family
ID=5768782
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE2019341A Expired DE2019341C3 (de) | 1970-04-22 | 1970-04-22 | Einrichtung zur Simulierung von Strömungswirkungen in einer gerinnenden Flüssigkeit, insbesondere in Blut |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US3714815A (https=) |
| JP (1) | JPS5434360B1 (https=) |
| CH (1) | CH535957A (https=) |
| DE (1) | DE2019341C3 (https=) |
| FR (1) | FR2089651A5 (https=) |
| GB (1) | GB1353481A (https=) |
| NL (1) | NL7104868A (https=) |
| SE (1) | SE381342B (https=) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3918533A1 (de) * | 1989-06-07 | 1990-12-13 | Hellmut Prof Dr Med Hartert | Verfahren zur bestimmung von gerinnungseigenschaften gerinnender fluessigkeiten wie blut oder blutplasma und vorrichtung zur durchfuehrung des verfahrens |
Families Citing this family (38)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2383444A1 (fr) * | 1977-03-11 | 1978-10-06 | Laborgeraete Analysensyst Gmbh | Mesure du temps de coagulation de sang |
| IT1076740B (it) * | 1977-04-28 | 1985-04-27 | E L V I Spa | Apparecchiatura per la determinazione dei parametri di elasticita' del sangue |
| DE2741060C2 (de) * | 1977-09-13 | 1982-06-24 | Chemisch-pharmazeutische Industrie KG 6380 Bad Homburg Dr. Eduard Fresenius | Verfahren und Vorrichtung zur Erfassung der Zustandsänderung einer Flüssigkeit |
| US4148216A (en) * | 1978-01-18 | 1979-04-10 | Do Mau T | Apparatus for determining the viscous behavior of a liquid during coagulation thereof |
| DE2908469A1 (de) * | 1979-03-05 | 1980-09-11 | Fresenius Chem Pharm Ind | Verfahren und vorrichtung zur bestimmung der visko-elastischen eigenschaften von fluiden |
| FR2455273A2 (fr) * | 1979-04-27 | 1980-11-21 | Probio Dms | Perfectionnements apportes aux dispositifs de thromboelastographie |
| US4317363A (en) * | 1980-06-16 | 1982-03-02 | Abbott Laboratories | Elastomer instrument |
| FR2535052A1 (fr) * | 1982-10-25 | 1984-04-27 | Agronomique Inst Nat Rech | Procede et appareil de mesure des proprietes rheologiques de corps semi-solides par cisaillement harmonique en rotation |
| FR2566908B1 (fr) * | 1984-06-27 | 1986-07-18 | Girolami Antoine | Coagulometre et procede de mesure du temps de coagulation d'echantillons de produits fluides |
| GB8720377D0 (en) * | 1987-08-28 | 1987-10-07 | Shell Int Research | Journal bearing simulator |
| GB2223853B (en) * | 1988-10-04 | 1992-08-26 | Plint & Partners Ltd | Viscometer and method of measuring viscosity |
| DE4437475C1 (de) * | 1994-10-19 | 1996-04-04 | Andreas Calatzis | Vorrichtung zum Messen der Koagulationseigenschaften von Test-Flüssigkeiten |
| JP3905124B2 (ja) * | 1994-10-19 | 2007-04-18 | ペンタファルム アクチェンゲゼルシャフト | 試液の凝結特性測定装置 |
| DE19542225B4 (de) * | 1995-11-01 | 2011-05-26 | L.U.M. Gmbh | Verfahren und Vorrichtung zur Bestimmung von rheologischen und mechanischen Stoffkenngrößen |
| US7179652B2 (en) * | 1999-02-22 | 2007-02-20 | Haemoscope Corporation | Protocol for monitoring platelet inhibition |
| US6225126B1 (en) | 1999-02-22 | 2001-05-01 | Haemoscope Corporation | Method and apparatus for measuring hemostasis |
| US8008086B2 (en) * | 1999-02-22 | 2011-08-30 | Cora Healthcare, Inc. | Protocol for monitoring direct thrombin inhibition |
| US7732213B2 (en) * | 1999-02-22 | 2010-06-08 | Coramed Healthcare, Inc. | Method of evaluating patient hemostasis |
| DE19939252A1 (de) * | 1999-08-16 | 2001-04-19 | Volker Goltz | Verfahren und Vorrichtung zur Untersuchung von Blut |
| US7524670B2 (en) * | 2003-08-05 | 2009-04-28 | Haemoscope Corporation | Protocol and apparatus for determining heparin-induced thrombocytopenia |
| GB0418474D0 (en) | 2004-08-12 | 2004-09-22 | Pentapharm Ltd | Device with novel and improved surface properties |
| US7745223B2 (en) * | 2004-08-12 | 2010-06-29 | C A Casyso Ag | Device with novel and improved surface properties |
| GB2444956A (en) | 2006-12-19 | 2008-06-25 | Pentapharm Ag | An apparatus and method for measuring the coagulation characteristics of a test liquid |
| EP2523000B1 (en) | 2008-12-23 | 2014-07-16 | C A Casyso AG | A cartridge device for a measuring system for measuring viscoelastic characteristics of a sample liquid, a corresponding measuring system, and a corresponding method |
| US8448499B2 (en) | 2008-12-23 | 2013-05-28 | C A Casyso Ag | Cartridge device for a measuring system for measuring viscoelastic characteristics of a sample liquid, a corresponding measuring system, and a corresponding method |
| US8383045B2 (en) * | 2009-01-16 | 2013-02-26 | C A Casyso Ag | Measuring unit for measuring characteristics of a sample liquid, in particular viscoelastic characteristics of a blood sample |
| EP2371284A1 (en) * | 2010-03-24 | 2011-10-05 | C A Casyso AG | Method and apparatus for determining at least one evaluation parameter of a blood sample |
| BR112015005288B1 (pt) | 2012-09-11 | 2022-08-09 | Board Of Regents, The University Of Texas System | Coagulômetro de sangue e método |
| US10175225B2 (en) | 2014-09-29 | 2019-01-08 | C A Casyso Ag | Blood testing system and method |
| US10539579B2 (en) | 2014-09-29 | 2020-01-21 | C A Casyso Gmbh | Blood testing system and method |
| US10288630B2 (en) | 2014-09-29 | 2019-05-14 | C A Casyso Gmbh | Blood testing system and method |
| US9897618B2 (en) | 2014-09-29 | 2018-02-20 | C A Casyso Gmbh | Blood testing system |
| US10816559B2 (en) | 2014-09-29 | 2020-10-27 | Ca Casyso Ag | Blood testing system and method |
| US10295554B2 (en) | 2015-06-29 | 2019-05-21 | C A Casyso Gmbh | Blood testing system and method |
| US10473674B2 (en) | 2016-08-31 | 2019-11-12 | C A Casyso Gmbh | Controlled blood delivery to mixing chamber of a blood testing cartridge |
| US11644401B2 (en) | 2017-01-26 | 2023-05-09 | Enicor Gmbh | Devices and methods for measuring viscoelastic changes of a sample |
| US10843185B2 (en) | 2017-07-12 | 2020-11-24 | Ca Casyso Gmbh | Autoplatelet cartridge device |
| US11781961B1 (en) | 2020-03-26 | 2023-10-10 | Rheonics Gmbh | Method and device for monitoring transformation processes of fluids |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR1283946A (fr) * | 1960-12-28 | 1962-02-09 | Appareil à mesurer le temps de coagulation sanguine |
-
1970
- 1970-04-22 DE DE2019341A patent/DE2019341C3/de not_active Expired
-
1971
- 1971-04-13 NL NL7104868A patent/NL7104868A/xx not_active Application Discontinuation
- 1971-04-14 FR FR7113166A patent/FR2089651A5/fr not_active Expired
- 1971-04-15 US US00134143A patent/US3714815A/en not_active Expired - Lifetime
- 1971-04-21 SE SE7105201A patent/SE381342B/xx unknown
- 1971-04-21 CH CH580171A patent/CH535957A/de not_active IP Right Cessation
- 1971-04-21 JP JP2534971A patent/JPS5434360B1/ja active Pending
- 1971-04-21 GB GB1038571*[A patent/GB1353481A/en not_active Expired
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3918533A1 (de) * | 1989-06-07 | 1990-12-13 | Hellmut Prof Dr Med Hartert | Verfahren zur bestimmung von gerinnungseigenschaften gerinnender fluessigkeiten wie blut oder blutplasma und vorrichtung zur durchfuehrung des verfahrens |
Also Published As
| Publication number | Publication date |
|---|---|
| DE2019341B2 (de) | 1979-04-19 |
| NL7104868A (https=) | 1971-10-26 |
| CH535957A (de) | 1973-04-15 |
| GB1353481A (en) | 1974-05-15 |
| DE2019341A1 (de) | 1971-11-04 |
| JPS5434360B1 (https=) | 1979-10-26 |
| US3714815A (en) | 1973-02-06 |
| SE381342B (sv) | 1975-12-01 |
| FR2089651A5 (https=) | 1972-01-07 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DE2019341C3 (de) | Einrichtung zur Simulierung von Strömungswirkungen in einer gerinnenden Flüssigkeit, insbesondere in Blut | |
| DE2201149A1 (de) | Verfahren und Vorrichtung zur Messung der Viskositaet von nativem Saeugetierblut | |
| DE2909087A1 (de) | Verfahren und vorrichtung zur ermittlung des viskositaetsverhaltens von massen | |
| Blantz et al. | Relation of distal tubular delivery and reabsorptive rate to nephron filtration | |
| DE2246675C3 (de) | Zentrifuge zum Zentrifugieren von Blut für die Ermittlung charakteristischer Blutsenkungswerte | |
| Montandon | A new technique for vestibular investigation | |
| Wieland et al. | Acute effects of real and imagined endurance exercise on sustained attention performance | |
| DE2413285C3 (de) | Verfahren und Anordnungen zur Gewinnung von einer Blutsenkung entsprechenden Meßwerten | |
| DE7014787U (de) | Vorrichtung zur Bestimmung der Elastizität von gerinnenden Flüssigkeiten, insbesondere von Blut | |
| DE845720C (de) | Geraet zur Bestimmung der Elastizitaet von gerinnenden Fluessigkeiten | |
| DE3434154C2 (https=) | ||
| Chapman | Reextension mechanism of a scyphistoma's tentacle | |
| DE2227943A1 (de) | Geraet zum messen des gerinnungszeitpunktes von insbesondere menschlichem plasma | |
| Carron et al. | Effects of practice upon individual differences and intra-variability in a motor skill | |
| DE4035034C1 (en) | Measuring blood clotting and thrombocyte action - by mixing blood sample with clotting retardant and measuring time required start agglutination | |
| DE69431363T2 (de) | Sensor zur überwachung der ionenaktivität in biologischen flüssigkeiten | |
| DE746089C (de) | Verfahren und Vorrichtung zur Bestimmung der Koagulationszeit von Fluessigkeiten, insbesondere von Blut | |
| DE2726771C3 (de) | Vorrichtung zur elektrochemisch-enzymatischen Analyse strömender Flüssigkeiten | |
| DE2808039C2 (de) | Verfahren zur Bestimmung der osmotischen Fragilität von Blutzellen | |
| DE2613212C2 (de) | Verfahren zur Bestimmung des Fließverhaltens von Flüssigkeiten für medizinische und pharmazeutische Zwecke, sowie Vorrichtung zur Durchführung des Verfahrens | |
| DE69929092T2 (de) | Sensor zum messen der durchblutung vom gewebe | |
| DE905569C (de) | Verfahren zur Herstellung eines Lachsersatzproduktes | |
| DE2129579A1 (de) | Vorrichtung zum Pruefen und Aufzeichnen von Dehnungscharakteristiken von dehnbaren Stoffen | |
| AT383487B (de) | Diagnosegeraet zur erfassung der axialen bewegung von koerperteilen | |
| DE720334C (de) | Verfahren und Vorrichtung zum Feststellen und Anzeigen des Schnittpunktes eingelabter Kaesereimilch |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| OI | Miscellaneous see part 1 | ||
| BGA | New person/name/address of the applicant | ||
| C3 | Grant after two publication steps (3rd publication) | ||
| 8327 | Change in the person/name/address of the patent owner |
Owner name: FRESENIUS AG, 6380 BAD HOMBURG, DE |
|
| 8327 | Change in the person/name/address of the patent owner |
Owner name: HARTERT, HELLMUT, PROF. DR.MED., 6750 KAISERSLAUTE |