DE19983247T1 - Mikroemulsionsvorkonzentrate, die einen Piperidin-Substanz-P-Antagonisten enthalten - Google Patents

Mikroemulsionsvorkonzentrate, die einen Piperidin-Substanz-P-Antagonisten enthalten

Info

Publication number
DE19983247T1
DE19983247T1 DE19983247T DE19983247T DE19983247T1 DE 19983247 T1 DE19983247 T1 DE 19983247T1 DE 19983247 T DE19983247 T DE 19983247T DE 19983247 T DE19983247 T DE 19983247T DE 19983247 T1 DE19983247 T1 DE 19983247T1
Authority
DE
Germany
Prior art keywords
antagonist
microemulsion preconcentrates
piperidine substance
preconcentrates containing
piperidine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
DE19983247T
Other languages
German (de)
English (en)
Inventor
Steffen Lang
Kurt Liechti
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Novartis AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9811200.6A external-priority patent/GB9811200D0/en
Priority claimed from GBGB9818105.0A external-priority patent/GB9818105D0/en
Application filed by Novartis AG filed Critical Novartis AG
Publication of DE19983247T1 publication Critical patent/DE19983247T1/de
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Pulmonology (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • Neurosurgery (AREA)
  • Molecular Biology (AREA)
  • Psychiatry (AREA)
  • Biophysics (AREA)
  • Dispersion Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Immunology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DE19983247T 1998-05-26 1999-05-26 Mikroemulsionsvorkonzentrate, die einen Piperidin-Substanz-P-Antagonisten enthalten Withdrawn DE19983247T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB9811200.6A GB9811200D0 (en) 1998-05-26 1998-05-26 Organic compounds
GBGB9818105.0A GB9818105D0 (en) 1998-08-19 1998-08-19 Organic compounds
PCT/EP1999/003623 WO1999061025A1 (en) 1998-05-26 1999-05-26 Microemulsion preconcentrates containing a piperidine substance p antagonist

Publications (1)

Publication Number Publication Date
DE19983247T1 true DE19983247T1 (de) 2001-05-31

Family

ID=26313736

Family Applications (2)

Application Number Title Priority Date Filing Date
DE19983247T Withdrawn DE19983247T1 (de) 1998-05-26 1999-05-26 Mikroemulsionsvorkonzentrate, die einen Piperidin-Substanz-P-Antagonisten enthalten
DE69914077T Expired - Lifetime DE69914077T2 (de) 1998-05-26 1999-05-26 Piperidine substanz-p-antagonist enthaltende emulsionsvorkonzentrate

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE69914077T Expired - Lifetime DE69914077T2 (de) 1998-05-26 1999-05-26 Piperidine substanz-p-antagonist enthaltende emulsionsvorkonzentrate

Country Status (30)

Country Link
US (2) US20020156099A1 (cg-RX-API-DMAC10.html)
EP (1) EP1082119B1 (cg-RX-API-DMAC10.html)
JP (1) JP4083985B2 (cg-RX-API-DMAC10.html)
KR (1) KR20010043669A (cg-RX-API-DMAC10.html)
CN (1) CN1270714C (cg-RX-API-DMAC10.html)
AR (1) AR018376A1 (cg-RX-API-DMAC10.html)
AT (1) ATE257380T1 (cg-RX-API-DMAC10.html)
AU (1) AU755134B2 (cg-RX-API-DMAC10.html)
BE (1) BE1012143A5 (cg-RX-API-DMAC10.html)
BR (1) BR9910696A (cg-RX-API-DMAC10.html)
CA (1) CA2333154C (cg-RX-API-DMAC10.html)
DE (2) DE19983247T1 (cg-RX-API-DMAC10.html)
DK (1) DK1082119T3 (cg-RX-API-DMAC10.html)
ES (1) ES2214859T3 (cg-RX-API-DMAC10.html)
FR (1) FR2779145B1 (cg-RX-API-DMAC10.html)
GB (1) GB2353473A (cg-RX-API-DMAC10.html)
HU (1) HUP0102202A3 (cg-RX-API-DMAC10.html)
ID (1) ID27096A (cg-RX-API-DMAC10.html)
IL (1) IL139501A0 (cg-RX-API-DMAC10.html)
IT (1) IT1313551B1 (cg-RX-API-DMAC10.html)
NO (1) NO20005920L (cg-RX-API-DMAC10.html)
NZ (1) NZ508325A (cg-RX-API-DMAC10.html)
PE (1) PE20000537A1 (cg-RX-API-DMAC10.html)
PL (1) PL344245A1 (cg-RX-API-DMAC10.html)
PT (1) PT1082119E (cg-RX-API-DMAC10.html)
RU (1) RU2240121C2 (cg-RX-API-DMAC10.html)
SK (1) SK17752000A3 (cg-RX-API-DMAC10.html)
TR (1) TR200003502T2 (cg-RX-API-DMAC10.html)
TW (1) TW537894B (cg-RX-API-DMAC10.html)
WO (1) WO1999061025A1 (cg-RX-API-DMAC10.html)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW537894B (en) 1998-05-26 2003-06-21 Novartis Ag A spontaneously dispersible pharmaceutical composition comprising a piperidine substance P antagonist
AU2003225260A1 (en) * 2002-04-22 2003-11-03 University Of Florida Microemulsions for selective molecular separation
GB0220953D0 (en) 2002-09-10 2002-10-23 Novartis Ag Organic compounds
US7842791B2 (en) 2002-12-19 2010-11-30 Nancy Jean Britten Dispersible pharmaceutical compositions
FR2935001B1 (fr) * 2008-08-14 2011-12-30 Commissariat Energie Atomique Emulsion fluorescente
FR2934954B1 (fr) 2008-08-14 2011-07-22 Commissariat Energie Atomique Emulsion fluorescente de vert d'indocyanine
FR2934953B1 (fr) 2008-08-14 2011-01-21 Commissariat Energie Atomique Nanoemulsions de nanocristaux
FR2934955B1 (fr) 2008-08-14 2011-07-08 Commissariat Energie Atomique Encapsulation d'agents therapeutiques lipophiles ou amphiphiles dans des nanoemulsions
EP2938324B1 (en) 2012-12-31 2023-11-08 JRX Biotechnology, Inc. Liquid topical pharmaceutical nano-emulsion formulations

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3305689A1 (de) 1983-02-18 1984-08-23 Mack Chem Pharm Pharmazeutische zubereitung mit retardwirkung
US5342625A (en) * 1988-09-16 1994-08-30 Sandoz Ltd. Pharmaceutical compositions comprising cyclosporins
MY110227A (en) * 1991-08-12 1998-03-31 Ciba Geigy Ag 1-acylpiperindine compounds.
DE4220616C2 (de) 1992-06-24 1994-12-22 Byk Gulden Lomberg Chem Fab Dexniguldipin zur intravenösen Verabreichung
DK0589843T3 (da) 1992-09-25 2002-04-02 Novartis Ag Cyclosporinholdige farmaceutiske præparater
GB2278780B (en) * 1993-05-27 1998-10-14 Sandoz Ltd Macrolide formulations
DE69535127T2 (de) * 1994-03-18 2007-02-15 Supernus Pharmaceuticals, Inc. Emulgierte arzneistoffabgabesysteme
TW397825B (en) * 1994-10-14 2000-07-11 Novartis Ag Aroyl-piperidine derivatives
GB2308545B (en) 1994-10-26 1999-06-02 Novartis Ag Pharmaceutical microemulsion preconcentrates
MY129435A (en) * 1994-10-26 2007-04-30 Novartis Ag Pharmaceutical microemulsion preconcentrates
FR2728165A1 (fr) * 1994-12-19 1996-06-21 Oreal Utilisation d'un antagoniste de substance p pour le traitement des rougeurs cutanees d'origine neurogene
FR2728169A1 (fr) * 1994-12-19 1996-06-21 Oreal Utilisation d'un antagoniste de substance p pour le traitement des prurits et des dysesthesies oculaires ou palpebrales
DE69617226T2 (de) * 1995-03-27 2002-07-25 Hisamitsu Pharmaceutical Co., Inc. Piperidinderivate.
NZ280689A (en) 1995-12-15 1997-08-22 Bernard Charles Sherma Sherman Pharmaceutical composition comprising a cyclosporipharmaceutical composition comprising a cyclosporin; a tocol, tocopherol or tocotrienol; and propylen; a tocol, tocopherol or tocotrienol; and propylene carbonate or polyethylene glycol ne carbonate or polyethylene glycol
GB9601120D0 (en) 1996-01-19 1996-03-20 Sandoz Ltd Organic compounds
WO1997045119A1 (en) 1996-05-24 1997-12-04 Novartis Ag Use of substance p antagonists for treating social phobia
TW537894B (en) 1998-05-26 2003-06-21 Novartis Ag A spontaneously dispersible pharmaceutical composition comprising a piperidine substance P antagonist

Also Published As

Publication number Publication date
US20020156099A1 (en) 2002-10-24
BR9910696A (pt) 2001-01-30
HK1035137A1 (en) 2001-11-16
CA2333154A1 (en) 1999-12-02
NZ508325A (en) 2003-06-30
PL344245A1 (en) 2001-10-08
IT1313551B1 (it) 2002-09-09
PE20000537A1 (es) 2000-07-10
US6949257B2 (en) 2005-09-27
DE69914077T2 (de) 2004-06-09
SK17752000A3 (sk) 2001-05-10
CA2333154C (en) 2008-07-08
GB2353473A (en) 2001-02-28
WO1999061025A1 (en) 1999-12-02
AU4500899A (en) 1999-12-13
AR018376A1 (es) 2001-11-14
TR200003502T2 (tr) 2001-04-20
EP1082119A1 (en) 2001-03-14
NO20005920L (no) 2001-01-25
CN1270714C (zh) 2006-08-23
RU2240121C2 (ru) 2004-11-20
FR2779145A1 (fr) 1999-12-03
GB0028506D0 (en) 2001-01-10
JP2002516280A (ja) 2002-06-04
ITMI991164A1 (it) 2000-11-26
KR20010043669A (ko) 2001-05-25
DE69914077D1 (de) 2004-02-12
CN1303285A (zh) 2001-07-11
HUP0102202A3 (en) 2003-01-28
FR2779145B1 (fr) 2004-07-30
PT1082119E (pt) 2004-05-31
BE1012143A5 (fr) 2000-05-02
EP1082119B1 (en) 2004-01-07
AU755134B2 (en) 2002-12-05
TW537894B (en) 2003-06-21
JP4083985B2 (ja) 2008-04-30
US20030152626A1 (en) 2003-08-14
ID27096A (id) 2001-03-01
ATE257380T1 (de) 2004-01-15
ES2214859T3 (es) 2004-09-16
NO20005920D0 (no) 2000-11-23
HUP0102202A2 (hu) 2001-11-28
DK1082119T3 (da) 2004-04-13
IL139501A0 (en) 2001-11-25

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Legal Events

Date Code Title Description
8141 Disposal/no request for examination