DE1904325C3 - 9alpha-unsubstituierte 1 lbeta-Chlor-19-norsteroide, Verfahren zu deren Herstellung und diese enthaltende pharmazeutische Zusammensetzungen - Google Patents

9alpha-unsubstituierte 1 lbeta-Chlor-19-norsteroide, Verfahren zu deren Herstellung und diese enthaltende pharmazeutische Zusammensetzungen

Info

Publication number
DE1904325C3
DE1904325C3 DE1904325A DE1904325A DE1904325C3 DE 1904325 C3 DE1904325 C3 DE 1904325C3 DE 1904325 A DE1904325 A DE 1904325A DE 1904325 A DE1904325 A DE 1904325A DE 1904325 C3 DE1904325 C3 DE 1904325C3
Authority
DE
Germany
Prior art keywords
dione
chloro
methylene
norpregn
acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE1904325A
Other languages
German (de)
English (en)
Other versions
DE1904325B2 (de
DE1904325A1 (de
Inventor
Gordon Hanley Greenford Middlesex Phillipps
Leslie London Stephenson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Glaxo Laboratories Ltd
Original Assignee
Glaxo Laboratories Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Laboratories Ltd filed Critical Glaxo Laboratories Ltd
Publication of DE1904325A1 publication Critical patent/DE1904325A1/de
Publication of DE1904325B2 publication Critical patent/DE1904325B2/de
Application granted granted Critical
Publication of DE1904325C3 publication Critical patent/DE1904325C3/de
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
    • C07J7/0005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21
    • C07J7/001—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group
    • C07J7/0015—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group not substituted in position 17 alfa
    • C07J7/0025—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group not substituted in position 17 alfa substituted in position 16
    • C07J7/0035—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group not substituted in position 17 alfa substituted in position 16 by a hydroxy group free esterified or etherified
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J13/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17
    • C07J13/005—Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17 with double bond in position 16 (17)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J53/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by condensation with a carbocyclic rings or by formation of an additional ring by means of a direct link between two ring carbon atoms, including carboxyclic rings fused to the cyclopenta(a)hydrophenanthrene skeleton are included in this class
    • C07J53/002—Carbocyclic rings fused
    • C07J53/004—3 membered carbocyclic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
    • C07J7/0005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21
    • C07J7/001—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group
    • C07J7/004—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group substituted in position 17 alfa
    • C07J7/005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group substituted in position 17 alfa substituted in position 16
    • C07J7/0055—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005—Oxygen-containing hetero ring
    • C07J71/001—Oxiranes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0036—Nitrogen-containing hetero ring
    • C07J71/0057—Nitrogen and oxygen
    • C07J71/0068—Nitrogen and oxygen at position 16(17)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J73/00—Steroids in which the cyclopenta[a]hydrophenanthrene skeleton has been modified by substitution of one or two carbon atoms by hetero atoms
    • C07J73/001—Steroids in which the cyclopenta[a]hydrophenanthrene skeleton has been modified by substitution of one or two carbon atoms by hetero atoms by one hetero atom
    • C07J73/003—Steroids in which the cyclopenta[a]hydrophenanthrene skeleton has been modified by substitution of one or two carbon atoms by hetero atoms by one hetero atom by oxygen as hetero atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE1904325A 1968-01-29 1969-01-29 9alpha-unsubstituierte 1 lbeta-Chlor-19-norsteroide, Verfahren zu deren Herstellung und diese enthaltende pharmazeutische Zusammensetzungen Expired DE1904325C3 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB4570/68A GB1260465A (en) 1968-01-29 1968-01-29 11beta-CHLORO-19-NOR-STEROIDS

Publications (3)

Publication Number Publication Date
DE1904325A1 DE1904325A1 (de) 1969-09-04
DE1904325B2 DE1904325B2 (de) 1978-02-16
DE1904325C3 true DE1904325C3 (de) 1978-10-26

Family

ID=9779640

Family Applications (1)

Application Number Title Priority Date Filing Date
DE1904325A Expired DE1904325C3 (de) 1968-01-29 1969-01-29 9alpha-unsubstituierte 1 lbeta-Chlor-19-norsteroide, Verfahren zu deren Herstellung und diese enthaltende pharmazeutische Zusammensetzungen

Country Status (14)

Country Link
JP (2) JPS4828907B1 (US20110009641A1-20110113-C00185.png)
AT (1) AT309703B (US20110009641A1-20110113-C00185.png)
BE (1) BE727578A (US20110009641A1-20110113-C00185.png)
BR (1) BR6905985D0 (US20110009641A1-20110113-C00185.png)
CH (2) CH592688A5 (US20110009641A1-20110113-C00185.png)
DE (1) DE1904325C3 (US20110009641A1-20110113-C00185.png)
DK (1) DK128715B (US20110009641A1-20110113-C00185.png)
ES (1) ES363068A1 (US20110009641A1-20110113-C00185.png)
FR (1) FR2000924A1 (US20110009641A1-20110113-C00185.png)
GB (1) GB1260465A (US20110009641A1-20110113-C00185.png)
IE (1) IE33924B1 (US20110009641A1-20110113-C00185.png)
IL (1) IL31515A0 (US20110009641A1-20110113-C00185.png)
NL (1) NL6901342A (US20110009641A1-20110113-C00185.png)
SE (2) SE386903B (US20110009641A1-20110113-C00185.png)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS52119945U (US20110009641A1-20110113-C00185.png) * 1976-03-08 1977-09-12
US5710293A (en) * 1995-10-13 1998-01-20 The Population Council, Center For Biomedical Research Method of preparation of ester derivatives of steroids

Also Published As

Publication number Publication date
BE727578A (US20110009641A1-20110113-C00185.png) 1969-07-29
JPS4830051B1 (US20110009641A1-20110113-C00185.png) 1973-09-17
DK128715B (da) 1974-06-24
AT309703B (de) 1973-08-27
DE1904325B2 (de) 1978-02-16
ES363068A1 (es) 1971-06-16
NL6901342A (US20110009641A1-20110113-C00185.png) 1969-07-31
FR2000924A1 (US20110009641A1-20110113-C00185.png) 1969-09-19
IE33924B1 (en) 1974-12-11
IL31515A0 (en) 1969-03-27
DE1904325A1 (de) 1969-09-04
CH578017A5 (US20110009641A1-20110113-C00185.png) 1976-07-30
SE386903B (sv) 1976-08-23
IE33924L (en) 1969-07-29
BR6905985D0 (pt) 1973-04-19
GB1260465A (en) 1972-01-19
CH592688A5 (US20110009641A1-20110113-C00185.png) 1977-11-15
SE364267B (US20110009641A1-20110113-C00185.png) 1974-02-18
JPS4828907B1 (US20110009641A1-20110113-C00185.png) 1973-09-05

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Legal Events

Date Code Title Description
C3 Grant after two publication steps (3rd publication)
8340 Patent of addition ceased/non-payment of fee of main patent