DE1815802A1 - Verfahren zur Herstellung von substituierten Phenylessigsaeuren - Google Patents

Verfahren zur Herstellung von substituierten Phenylessigsaeuren

Info

Publication number
DE1815802A1
DE1815802A1 DE19681815802 DE1815802A DE1815802A1 DE 1815802 A1 DE1815802 A1 DE 1815802A1 DE 19681815802 DE19681815802 DE 19681815802 DE 1815802 A DE1815802 A DE 1815802A DE 1815802 A1 DE1815802 A1 DE 1815802A1
Authority
DE
Germany
Prior art keywords
acid
general formula
substituted
phenyl
solution
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
DE19681815802
Other languages
German (de)
English (en)
Inventor
Sallmann Dr Alfred
Pfister Dr Rudolf
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
JR Geigy AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CH1789267A external-priority patent/CH487840A/de
Priority claimed from CH1789367A external-priority patent/CH485667A/de
Application filed by JR Geigy AG filed Critical JR Geigy AG
Publication of DE1815802A1 publication Critical patent/DE1815802A1/de
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/32—Oxygen atoms
    • C07D209/38—Oxygen atoms in positions 2 and 3, e.g. isatin

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Indole Compounds (AREA)
DE19681815802 1967-12-20 1968-12-19 Verfahren zur Herstellung von substituierten Phenylessigsaeuren Pending DE1815802A1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH1789267A CH487840A (de) 1967-12-20 1967-12-20 Verfahren zur Herstellung von substituierten Phenylessigsäuren
CH1789367A CH485667A (de) 1967-12-20 1967-12-20 Verfahren zur Herstellung von substituierten Phenylessigsäuren

Publications (1)

Publication Number Publication Date
DE1815802A1 true DE1815802A1 (de) 1969-07-10

Family

ID=25720227

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19681815802 Pending DE1815802A1 (de) 1967-12-20 1968-12-19 Verfahren zur Herstellung von substituierten Phenylessigsaeuren

Country Status (16)

Country Link
JP (4) JPS5220469B1 (xx)
AT (1) AT284823B (xx)
BE (1) BE725793A (xx)
CS (2) CS151495B2 (xx)
DE (1) DE1815802A1 (xx)
DK (1) DK125461B (xx)
ES (1) ES361666A1 (xx)
FI (1) FI49600C (xx)
FR (1) FR1595382A (xx)
GB (1) GB1257190A (xx)
IE (1) IE32591B1 (xx)
IL (1) IL31296A (xx)
NL (1) NL6817965A (xx)
NO (1) NO125724B (xx)
SE (1) SE366296B (xx)
YU (1) YU32986B (xx)

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4166128A (en) * 1977-06-23 1979-08-28 Asahi Kasei Kogyo Kabushiki Kaisha Substituted phenylglycolic acid and its pharmaceutically acceptable esters and salts, and processes for preparing the same
FR2499980A1 (fr) * 1981-02-16 1982-08-20 Ciba Geigy Ag Le (o-(2,6-dichloranilino))-phenylacetate de n-methyl-d-glucammonium, son obtention et les preparations pharmaceutiques le contenant
FR2500751A1 (fr) * 1981-02-24 1982-09-03 Ciba Geigy Ag Compositions pharmaceutiques anti-inflammatoires topiques a base de sels d'acides carboxyliques, nouveaux sels d'acides carboxyliques et leur preparation
EP0122219A2 (de) * 1983-01-12 1984-10-17 Ciba-Geigy Ag Resinat einer substituierten Carbonsäure, Verfahren zu seiner Herstellung, seine Verwendung und dieses enthaltende pharmazeutische Präparate
US5403958A (en) * 1990-09-04 1995-04-04 Hitachi Chemical Co., Ltd. Electrophotographic member
WO2006058592A1 (en) 2004-12-01 2006-06-08 Merck Patent Gmbh Novel specific caspase-10 inhibitors
EP2756843A2 (en) 2006-07-25 2014-07-23 Techfields Biochem Co. Ltd Positively charged water-soluble prodrugs of diclofenac with very fast skin penetration rate
US11834388B2 (en) 2022-02-25 2023-12-05 Fudan University Continuous-flow preparation method of diclofenac sodium
US11905229B2 (en) 2022-02-25 2024-02-20 Fudan University Method for synthesizing diclofenac sodium

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1112024B (it) * 1979-02-23 1986-01-13 Alcar Srl Processo per la preparazione dell'acido o.(2,6-dicloroanilino)-fenilacetico
JPS6341143U (xx) * 1986-09-02 1988-03-17
US6355680B1 (en) * 1996-02-20 2002-03-12 Exocell, Inc. Albumin-binding compounds that prevent nonenzymatic glycation and that may be used for treatment of glycation-related pathologies
AR061623A1 (es) 2006-06-26 2008-09-10 Novartis Ag Derivados de acido fenilacetico

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5220469A (en) * 1975-08-08 1977-02-16 Mitsui Toatsu Chem Inc Method for grading granule
JPS5851859B2 (ja) * 1978-08-11 1983-11-18 株式会社日立製作所 帳票送り出し装置

Cited By (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4166128A (en) * 1977-06-23 1979-08-28 Asahi Kasei Kogyo Kabushiki Kaisha Substituted phenylglycolic acid and its pharmaceutically acceptable esters and salts, and processes for preparing the same
FR2499980A1 (fr) * 1981-02-16 1982-08-20 Ciba Geigy Ag Le (o-(2,6-dichloranilino))-phenylacetate de n-methyl-d-glucammonium, son obtention et les preparations pharmaceutiques le contenant
WO1982002889A1 (en) * 1981-02-16 1982-09-02 Geigy Ag Ciba Ammonium salts of a substituted carbonic acid,preparation method thereof,utilization and medicinal preparations containing them
FR2500751A1 (fr) * 1981-02-24 1982-09-03 Ciba Geigy Ag Compositions pharmaceutiques anti-inflammatoires topiques a base de sels d'acides carboxyliques, nouveaux sels d'acides carboxyliques et leur preparation
EP0122219A2 (de) * 1983-01-12 1984-10-17 Ciba-Geigy Ag Resinat einer substituierten Carbonsäure, Verfahren zu seiner Herstellung, seine Verwendung und dieses enthaltende pharmazeutische Präparate
EP0122219A3 (en) * 1983-01-12 1985-05-08 Ciba-Geigy Ag Substituted carboxylic-acid resins, process for their manafacture, use thereof and pharmaceutical compositions containing these resins
AT391467B (de) * 1983-01-12 1990-10-10 Ciba Geigy Ag Verfahren zur herstellung eines beladenen ionenaustauscherharzes sowie die herstellung pharmazeutischer praeparate hiemit
US5403958A (en) * 1990-09-04 1995-04-04 Hitachi Chemical Co., Ltd. Electrophotographic member
WO2006058592A1 (en) 2004-12-01 2006-06-08 Merck Patent Gmbh Novel specific caspase-10 inhibitors
EP2756843A2 (en) 2006-07-25 2014-07-23 Techfields Biochem Co. Ltd Positively charged water-soluble prodrugs of diclofenac with very fast skin penetration rate
US11834388B2 (en) 2022-02-25 2023-12-05 Fudan University Continuous-flow preparation method of diclofenac sodium
US11905229B2 (en) 2022-02-25 2024-02-20 Fudan University Method for synthesizing diclofenac sodium

Also Published As

Publication number Publication date
CS151496B2 (xx) 1973-10-19
JPS5526132B1 (xx) 1980-07-11
JPS5526131B1 (xx) 1980-07-11
FI49600B (xx) 1975-04-30
YU298368A (en) 1975-06-30
JPS5220469B1 (xx) 1977-06-03
IL31296A (en) 1972-06-28
GB1257190A (xx) 1971-12-15
CS151495B2 (xx) 1973-10-19
SE366296B (xx) 1974-04-22
BE725793A (xx) 1969-06-20
YU32986B (en) 1975-12-31
DK125461B (da) 1973-02-26
NO125724B (xx) 1972-10-23
IL31296A0 (en) 1969-02-27
AT284823B (de) 1970-09-25
NL6817965A (xx) 1969-06-24
FR1595382A (xx) 1970-06-08
JPS5635664B1 (xx) 1981-08-19
IE32591L (en) 1969-06-20
FI49600C (fi) 1975-08-11
IE32591B1 (en) 1973-09-19
ES361666A1 (es) 1970-11-16

Similar Documents

Publication Publication Date Title
DE1815802A1 (de) Verfahren zur Herstellung von substituierten Phenylessigsaeuren
CH615172A5 (xx)
DE2165260A1 (de) Verfahren zur Herstellung von N-substituierten Dibenzo eckige Klammer auf b,f eckige Klammer zu thiepin-10-methylaminen und zugehörige neue Zwischenprodukte
DE1620442C3 (de) Verfahren zur Herstellung von 1-Acylindolverbindungen
DE2435613B2 (de) Dibenzoxepinone, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
DE3049405A1 (de) Neue derivate von antiphlogistisch wirksamen carbonsaeuren, ihre herstellung und medizinische anwendung
DE1543639A1 (de) Verfahren zur Herstellung von neuen substituierten Phenylessigsaeuren
DE2224655A1 (de) Tricyclische Verbindungen und Verfahren zu deren Herstellung
DE1933985A1 (de) Neue Cycloalkancarbonsaeurederivate und Verfahren zu ihrer Herstellung
DE1618465C3 (de) Phenylessigsäureester, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
DE2004038C3 (de) 5-Cyclohexyl-1-indancarbonsäuren,,deren Niedrigalkyl- und tert.-Aminoniedrigalkylester, nicht-toxische pharmakologisch verträgliche Salze und Verfahren zu deren Herstellung
DE1965981C3 (de) 9-Phenyl-lO-oxopiperazino [l,2-a]-indole und Verfahren zu ihrer Herstellung
DE2056173A1 (de) 3,5 Diphenyl 4 pyrazolessigsaure. ihre m 1 Stellung substituierten Derivate und Verfahren zur Herstellung dieser Verbin düngen
DE3235850A1 (de) Neue indolessigsaeureesterderivate und verfahren zur herstellung derselben
DE2007700C2 (de) Substituierte o-Anilino-phenäthylalkohole, Verfahren zu ihrer Herstellung und therapeutische Präparate
CH632487A5 (en) Process for preparing novel cyanoacetanilide derivatives
DE2721265C2 (de) Verfahren zur Herstellung von Di- n-propylacetonitril
AT332877B (de) Verfahren zur herstellung von neuen 6-aza-1,2-dihydro-3h-1,4- benzodiazepinen, deren optischen isomeren und deren salzen
CH485667A (de) Verfahren zur Herstellung von substituierten Phenylessigsäuren
DE2164662A1 (de) Indanderivate und Verfahren zu ihrer Herstellung
CH487840A (de) Verfahren zur Herstellung von substituierten Phenylessigsäuren
DE2644789A1 (de) Alkylen-di-phenylalk(en)ylcarbonsaeuren und ihre herstellung und verwendung
DE2118365C3 (de) m-Benzoylphenylessigsäureester, Verfahren zu ihrer Herstellung und pharmazeutische Zusammensetzungen
AT354432B (de) Verfahren zur herstellung von 3-indolylessig- saeuren
AT374166B (de) Verfahren zur herstellung von neuen indan-1 -carbonsaeure-derivaten und deren salzen