DE1793050C3 - Substituierte cyclische und acyclische Amidine sowie Mittel zur Bekämpfung der Helminthiasis, die diese Verbindungen enthalten - Google Patents

Substituierte cyclische und acyclische Amidine sowie Mittel zur Bekämpfung der Helminthiasis, die diese Verbindungen enthalten

Info

Publication number
DE1793050C3
DE1793050C3 DE1793050A DE1793050A DE1793050C3 DE 1793050 C3 DE1793050 C3 DE 1793050C3 DE 1793050 A DE1793050 A DE 1793050A DE 1793050 A DE1793050 A DE 1793050A DE 1793050 C3 DE1793050 C3 DE 1793050C3
Authority
DE
Germany
Prior art keywords
solution
hydroxyphenyl
methyl
compounds
mol
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE1793050A
Other languages
German (de)
English (en)
Other versions
DE1793050A1 (de
DE1793050B2 (de
Inventor
James William Lyme Conn. Mcfarland (V.St.A.)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Inc
Original Assignee
Pfizer Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Inc filed Critical Pfizer Inc
Publication of DE1793050A1 publication Critical patent/DE1793050A1/de
Publication of DE1793050B2 publication Critical patent/DE1793050B2/de
Application granted granted Critical
Publication of DE1793050C3 publication Critical patent/DE1793050C3/de
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/06—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/10—Anthelmintics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C243/00—Compounds containing chains of nitrogen atoms singly-bound to each other, e.g. hydrazines, triazanes
    • C07C243/24—Hydrazines having nitrogen atoms of hydrazine groups acylated by carboxylic acids
    • C07C243/26—Hydrazines having nitrogen atoms of hydrazine groups acylated by carboxylic acids with acylating carboxyl groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C243/34—Hydrazines having nitrogen atoms of hydrazine groups acylated by carboxylic acids with acylating carboxyl groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of a carbon skeleton further substituted by nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C259/00—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups
    • C07C259/12—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups with replacement of the other oxygen atom of the carboxyl group by nitrogen atoms, e.g. N-hydroxyamidines
    • C07C259/14—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups with replacement of the other oxygen atom of the carboxyl group by nitrogen atoms, e.g. N-hydroxyamidines having carbon atoms of hydroxamidine groups bound to hydrogen atoms or to acyclic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/673—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by change of size of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/42—Unsaturated compounds containing hydroxy or O-metal groups
    • C07C59/52—Unsaturated compounds containing hydroxy or O-metal groups a hydroxy or O-metal group being bound to a carbon atom of a six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C65/00—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C65/01—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing hydroxy or O-metal groups
    • C07C65/03—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing hydroxy or O-metal groups monocyclic and having all hydroxy or O-metal groups bound to the ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/20—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D233/22—Radicals substituted by oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/20—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D233/24—Radicals substituted by nitrogen atoms not forming part of a nitro radical

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DE1793050A 1967-08-30 1968-07-27 Substituierte cyclische und acyclische Amidine sowie Mittel zur Bekämpfung der Helminthiasis, die diese Verbindungen enthalten Expired DE1793050C3 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US66425867A 1967-08-30 1967-08-30

Publications (3)

Publication Number Publication Date
DE1793050A1 DE1793050A1 (de) 1971-12-16
DE1793050B2 DE1793050B2 (de) 1975-01-23
DE1793050C3 true DE1793050C3 (de) 1975-09-11

Family

ID=24665273

Family Applications (1)

Application Number Title Priority Date Filing Date
DE1793050A Expired DE1793050C3 (de) 1967-08-30 1968-07-27 Substituierte cyclische und acyclische Amidine sowie Mittel zur Bekämpfung der Helminthiasis, die diese Verbindungen enthalten

Country Status (11)

Country Link
US (1) US3579510A (enExample)
JP (1) JPS4813108B1 (enExample)
BR (1) BR6801003D0 (enExample)
DE (1) DE1793050C3 (enExample)
DK (2) DK123710B (enExample)
FR (2) FR1584069A (enExample)
GB (1) GB1168361A (enExample)
IL (1) IL30383A (enExample)
NL (1) NL162074C (enExample)
NO (1) NO126440B (enExample)
SE (1) SE349579B (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3930001A (en) * 1971-11-30 1975-12-30 Pfizer 2-(Substituted)-5,6-dihydro-4H-1,4-thiazines used for the control of rice blast
US3890443A (en) * 1973-09-17 1975-06-17 Pfizer 2-(Substituted) thiazolines for the control of rice blast
US4490388A (en) * 1981-02-27 1984-12-25 Torii & Co., Ltd. Amidine compound and anticomplement agent comprising same
DE3211301A1 (de) * 1982-03-26 1983-09-29 Bayer Ag, 5090 Leverkusen Cyclische amidine, verfahren zu ihrer herstellung und die verwendung cyclischer amidine als katalysatoren fuer die haertung von epoxidharzen
WO1995007100A1 (en) * 1993-09-10 1995-03-16 Petrovax L.L.C. Compounds for the prevention and treatment of helminth infections

Also Published As

Publication number Publication date
BR6801003D0 (pt) 1973-07-03
NO126440B (enExample) 1973-02-05
DE1793050A1 (de) 1971-12-16
SE349579B (enExample) 1972-10-02
FR1584069A (enExample) 1969-12-12
US3579510A (en) 1971-05-18
NL162074B (nl) 1979-11-15
GB1168361A (en) 1969-10-22
NL162074C (nl) 1980-04-15
JPS4813108B1 (enExample) 1973-04-25
IL30383A0 (en) 1968-09-26
FR7991M (enExample) 1970-06-08
IL30383A (en) 1973-02-28
DE1793050B2 (de) 1975-01-23
NL6810601A (enExample) 1969-03-04
DK123710B (da) 1972-07-24
DK126785B (da) 1973-08-20

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Legal Events

Date Code Title Description
C3 Grant after two publication steps (3rd publication)
E77 Valid patent as to the heymanns-index 1977