DE1668124B2 - 9 alpha-unsubstituierte 11 beta- chlor-19-norsteroide, verfahren zu deren herstellung sowie diese enthaltende pharmazeutische zusammensetzungen - Google Patents

9 alpha-unsubstituierte 11 beta- chlor-19-norsteroide, verfahren zu deren herstellung sowie diese enthaltende pharmazeutische zusammensetzungen

Info

Publication number
DE1668124B2
DE1668124B2 DE1967G0050758 DEG0050758A DE1668124B2 DE 1668124 B2 DE1668124 B2 DE 1668124B2 DE 1967G0050758 DE1967G0050758 DE 1967G0050758 DE G0050758 A DEG0050758 A DE G0050758A DE 1668124 B2 DE1668124 B2 DE 1668124B2
Authority
DE
Germany
Prior art keywords
chloro
dione
ether
acid
chlorine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
DE1967G0050758
Other languages
German (de)
English (en)
Other versions
DE1668124A1 (de
Inventor
Joseph London; Phillipps Gordon Hanley Greenford Middlesex; Tulley Allan Birkdale Southport Lancashire; Elks (Großbritannien)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Glaxo Laboratories Ltd
Original Assignee
Glaxo Laboratories Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Laboratories Ltd filed Critical Glaxo Laboratories Ltd
Publication of DE1668124A1 publication Critical patent/DE1668124A1/de
Publication of DE1668124B2 publication Critical patent/DE1668124B2/de
Granted legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/567—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in position 17 alpha, e.g. mestranol, norethandrolone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/566—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol having an oxo group in position 17, e.g. estrone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J75/00—Processes for the preparation of steroids in general

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE1967G0050758 1966-07-29 1967-07-28 9 alpha-unsubstituierte 11 beta- chlor-19-norsteroide, verfahren zu deren herstellung sowie diese enthaltende pharmazeutische zusammensetzungen Granted DE1668124B2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB23066/67A GB1202521A (en) 1966-07-29 1966-07-29 01beta-CHLORO-19-NOR-STEROIDS
GB3427566 1966-07-29

Publications (2)

Publication Number Publication Date
DE1668124A1 DE1668124A1 (de) 1971-05-06
DE1668124B2 true DE1668124B2 (de) 1976-10-07

Family

ID=26256295

Family Applications (1)

Application Number Title Priority Date Filing Date
DE1967G0050758 Granted DE1668124B2 (de) 1966-07-29 1967-07-28 9 alpha-unsubstituierte 11 beta- chlor-19-norsteroide, verfahren zu deren herstellung sowie diese enthaltende pharmazeutische zusammensetzungen

Country Status (12)

Country Link
JP (2) JPS5021469B1 (fr)
AT (2) AT311564B (fr)
BE (1) BE702023A (fr)
CH (2) CH580644A5 (fr)
DE (1) DE1668124B2 (fr)
DK (2) DK129004B (fr)
FR (2) FR1565340A (fr)
GB (1) GB1202521A (fr)
IL (1) IL28411A (fr)
NL (1) NL6710459A (fr)
PL (1) PL79253B1 (fr)
SE (2) SE349025B (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1289521A (fr) * 1969-01-23 1972-09-20
GB1313659A (en) * 1969-07-25 1973-04-18 Glaxo Lab Ltd 9alpha-unsubstituted-11beta-chloro-19-norpregnane compounds
JPS5090183A (fr) * 1973-12-14 1975-07-19
JPS5090184A (fr) * 1973-12-14 1975-07-19

Also Published As

Publication number Publication date
SE350488B (fr) 1972-10-30
AT301766B (de) 1972-09-25
BE702023A (fr) 1968-01-29
DE1668124A1 (de) 1971-05-06
PL79253B1 (fr) 1975-06-30
DK131295B (da) 1975-06-23
JPS5021469B1 (fr) 1975-07-23
FR7812M (fr) 1970-05-20
IL28411A (en) 1972-07-26
DK129004B (da) 1974-08-05
JPS5224013B1 (fr) 1977-06-28
AT311564B (de) 1973-11-26
NL6710459A (fr) 1968-01-30
CH580644A5 (fr) 1976-10-15
DK131295C (fr) 1975-11-17
CH584724A5 (fr) 1977-02-15
FR1565340A (fr) 1969-05-02
GB1202521A (en) 1970-08-19
SE349025B (fr) 1972-09-18

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Legal Events

Date Code Title Description
C3 Grant after two publication steps (3rd publication)
E77 Valid patent as to the heymanns-index 1977
EHJ Ceased/non-payment of the annual fee