DE1598049B2 - Verfahren und vorrichtung zur technischen durchfuehrung der saeulenchromatographie - Google Patents
Verfahren und vorrichtung zur technischen durchfuehrung der saeulenchromatographieInfo
- Publication number
- DE1598049B2 DE1598049B2 DE19651598049 DE1598049A DE1598049B2 DE 1598049 B2 DE1598049 B2 DE 1598049B2 DE 19651598049 DE19651598049 DE 19651598049 DE 1598049 A DE1598049 A DE 1598049A DE 1598049 B2 DE1598049 B2 DE 1598049B2
- Authority
- DE
- Germany
- Prior art keywords
- column
- mixing
- separation
- columns
- chromatography
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 238000000034 method Methods 0.000 title claims description 13
- 238000004440 column chromatography Methods 0.000 title claims description 4
- 238000002156 mixing Methods 0.000 claims description 22
- 238000010586 diagram Methods 0.000 claims description 17
- 239000007788 liquid Substances 0.000 claims description 10
- 238000000926 separation method Methods 0.000 claims description 10
- 238000011049 filling Methods 0.000 claims description 9
- 238000004587 chromatography analysis Methods 0.000 claims description 8
- 239000003463 adsorbent Substances 0.000 claims description 7
- 230000000694 effects Effects 0.000 claims description 3
- 239000003480 eluent Substances 0.000 claims description 3
- 238000010828 elution Methods 0.000 claims description 3
- 230000015572 biosynthetic process Effects 0.000 claims description 2
- 239000000126 substance Substances 0.000 claims 3
- 238000004140 cleaning Methods 0.000 claims 2
- 238000009434 installation Methods 0.000 claims 2
- 241000863032 Trieres Species 0.000 claims 1
- 239000004566 building material Substances 0.000 claims 1
- 230000001419 dependent effect Effects 0.000 claims 1
- 238000011005 laboratory method Methods 0.000 claims 1
- 239000007791 liquid phase Substances 0.000 claims 1
- 239000003973 paint Substances 0.000 claims 1
- 238000002604 ultrasonography Methods 0.000 claims 1
- 230000002747 voluntary effect Effects 0.000 claims 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 7
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 4
- 230000000052 comparative effect Effects 0.000 description 4
- 239000008103 glucose Substances 0.000 description 4
- 235000000346 sugar Nutrition 0.000 description 4
- 150000001768 cations Chemical class 0.000 description 3
- 238000002474 experimental method Methods 0.000 description 3
- 150000002500 ions Chemical class 0.000 description 3
- 125000006850 spacer group Chemical group 0.000 description 3
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 description 2
- 229930091371 Fructose Natural products 0.000 description 2
- RFSUNEUAIZKAJO-ARQDHWQXSA-N Fructose Chemical compound OC[C@H]1O[C@](O)(CO)[C@@H](O)[C@@H]1O RFSUNEUAIZKAJO-ARQDHWQXSA-N 0.000 description 2
- 239000005715 Fructose Substances 0.000 description 2
- WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 description 2
- 239000004744 fabric Substances 0.000 description 2
- 229960004903 invert sugar Drugs 0.000 description 2
- 238000005342 ion exchange Methods 0.000 description 2
- 239000002904 solvent Substances 0.000 description 2
- PNEYBMLMFCGWSK-UHFFFAOYSA-N Alumina Chemical class [O-2].[O-2].[O-2].[Al+3].[Al+3] PNEYBMLMFCGWSK-UHFFFAOYSA-N 0.000 description 1
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical group [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 description 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 description 1
- 150000001450 anions Chemical class 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 238000005553 drilling Methods 0.000 description 1
- 238000011010 flushing procedure Methods 0.000 description 1
- 239000011521 glass Substances 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 238000003780 insertion Methods 0.000 description 1
- 230000037431 insertion Effects 0.000 description 1
- 238000011068 loading method Methods 0.000 description 1
- 229910052751 metal Inorganic materials 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
- 238000000746 purification Methods 0.000 description 1
- 230000029058 respiratory gaseous exchange Effects 0.000 description 1
- 238000007665 sagging Methods 0.000 description 1
- 150000008163 sugars Chemical class 0.000 description 1
- 230000008961 swelling Effects 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/26—Conditioning of the fluid carrier; Flow patterns
- G01N30/38—Flow patterns
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/10—Selective adsorption, e.g. chromatography characterised by constructional or operational features
- B01D15/22—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to the construction of the column
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/60—Construction of the column
- G01N30/6052—Construction of the column body
- G01N30/6069—Construction of the column body with compartments or bed substructure
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
- B01D15/36—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving ionic interaction, e.g. ion-exchange, ion-pair, ion-suppression or ion-exclusion
- B01D15/361—Ion-exchange
- B01D15/362—Cation-exchange
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
- B01D15/36—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving ionic interaction, e.g. ion-exchange, ion-pair, ion-suppression or ion-exclusion
- B01D15/361—Ion-exchange
- B01D15/363—Anion-exchange
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/60—Construction of the column
- G01N30/6004—Construction of the column end pieces
- G01N30/6017—Fluid distributors
Landscapes
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Treatment Of Liquids With Adsorbents In General (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DEB0082245 | 1965-06-03 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE1598049A1 DE1598049A1 (de) | 1969-12-11 |
| DE1598049B2 true DE1598049B2 (de) | 1972-04-06 |
Family
ID=6981430
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE19651598049 Pending DE1598049B2 (de) | 1965-06-03 | 1965-06-03 | Verfahren und vorrichtung zur technischen durchfuehrung der saeulenchromatographie |
Country Status (11)
Families Citing this family (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE359228B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * | 1970-11-20 | 1973-08-27 | Pharmacia Fine Chemicals Ab | |
| AU476229B2 (en) * | 1971-10-01 | 1976-09-16 | Suomen Sokeri Osakeyhtio | Liquid control apparatus for chromatography columns |
| US3928193A (en) * | 1975-02-14 | 1975-12-23 | Suomen Sokeri Oy | Process for large scale chromatography |
| JPS59122552A (ja) * | 1982-12-28 | 1984-07-16 | Mitsubishi Chem Ind Ltd | 水溶性染料の精製方法 |
| JPS59199768A (ja) * | 1983-04-27 | 1984-11-12 | Canon Inc | 染料精製装置 |
| JPS609753A (ja) * | 1983-06-30 | 1985-01-18 | Canon Inc | インク製造装置 |
| JPS609751A (ja) * | 1983-06-30 | 1985-01-18 | Canon Inc | インク製造装置 |
| JPS59199770A (ja) * | 1983-04-27 | 1984-11-12 | Canon Inc | 染料精製装置 |
| JPS609752A (ja) * | 1983-06-30 | 1985-01-18 | Canon Inc | インク製造装置 |
| JPS59199767A (ja) * | 1983-04-27 | 1984-11-12 | Canon Inc | 染料精製装置 |
| JPS609749A (ja) * | 1983-06-30 | 1985-01-18 | Canon Inc | インク製造装置 |
| JPS59199766A (ja) * | 1983-04-27 | 1984-11-12 | Canon Inc | 染料精製装置 |
| JPS59199769A (ja) * | 1983-04-27 | 1984-11-12 | Canon Inc | 染料精製装置 |
| JPS609750A (ja) * | 1983-06-30 | 1985-01-18 | Canon Inc | インク製造装置 |
| JPS59199765A (ja) * | 1983-04-27 | 1984-11-12 | Canon Inc | 染料精製装置 |
| DE3417411A1 (de) * | 1983-06-30 | 1985-01-03 | Canon K.K., Tokio/Tokyo | Tintenherstellungssystem |
| FR2575666B1 (fr) * | 1985-01-04 | 1989-08-18 | Centre Nat Rech Scient | Procede et dispositif pour la separation chromatographique de macromolecules biologiques |
| US4894152A (en) * | 1987-08-13 | 1990-01-16 | Cerex Corporation | Fluid control device |
| US4891133A (en) * | 1987-09-15 | 1990-01-02 | Cerex Corporation | Chromatography apparatus |
| FI97277C (fi) * | 1993-01-25 | 1996-11-25 | Suomen Sokeri Oy | Kromatografinen erotuskolonni, sen sisärakenteet ja kromatografinen erotusmenetelmä |
| US6663780B2 (en) | 1993-01-26 | 2003-12-16 | Danisco Finland Oy | Method for the fractionation of molasses |
| FI96225C (fi) | 1993-01-26 | 1996-05-27 | Cultor Oy | Menetelmä melassin fraktioimiseksi |
| US5795398A (en) | 1994-09-30 | 1998-08-18 | Cultor Ltd. | Fractionation method of sucrose-containing solutions |
| US6224776B1 (en) | 1996-05-24 | 2001-05-01 | Cultor Corporation | Method for fractionating a solution |
| FI20010977A7 (fi) | 2001-05-09 | 2002-11-10 | Danisco Sweeteners Oy | Kromatografinen erotusmenetelmä |
| WO2006092172A1 (en) * | 2005-03-02 | 2006-09-08 | Agilent Technologies, Inc. | Column with additional fluid introduction |
| HRP20180714T1 (hr) | 2009-07-30 | 2018-06-15 | F. Hoffmann - La Roche Ag | Separator stupaca za mobilnu kromatografiju |
| EP2619568A4 (en) * | 2010-09-23 | 2014-06-25 | Ge Healthcare Bio Sciences | ONE-WAY BARRIER AND CHROMATOGRAPHY SYSTEMS |
| JP6073811B2 (ja) | 2011-02-02 | 2017-02-01 | エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ | クロマトグラフィーカラムサポート |
| US10632461B2 (en) * | 2016-09-30 | 2020-04-28 | Canon Medical Systems Corporation | Chemical container |
| CN108582912B (zh) * | 2018-03-16 | 2020-01-14 | 无锡富仕德高科特材制造有限公司 | 低导热系数玻璃纤维复合材料及其制备方法 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3230167A (en) * | 1962-07-06 | 1966-01-18 | Perkin Elmer Corp | Elution chromatography |
| US3214247A (en) * | 1963-02-25 | 1965-10-26 | Universal Oil Prod Co | Fluid distributing means for packed chambers |
| US3310932A (en) * | 1964-12-14 | 1967-03-28 | Atlantic Refining Co | Gas chromatographic columns |
| US3334514A (en) * | 1964-12-16 | 1967-08-08 | Technicon Corp | Chromatographic column |
-
1965
- 1965-06-03 DE DE19651598049 patent/DE1598049B2/de active Pending
-
1966
- 1966-05-31 CH CH783666A patent/CH462116A/de unknown
- 1966-06-01 GB GB24449/66A patent/GB1075920A/en not_active Expired
- 1966-06-01 FI FI661437A patent/FI41876C/fi active
- 1966-06-02 NL NL666607638A patent/NL149603B/xx not_active IP Right Cessation
- 1966-06-02 SE SE07550/66A patent/SE338187B/xx unknown
- 1966-06-02 AT AT522166A patent/AT266049B/de active
- 1966-06-02 FR FR63822A patent/FR1481755A/fr not_active Expired
- 1966-06-03 JP JP41035922A patent/JPS5110115B1/ja active Pending
-
1968
- 1968-10-22 US US769666A patent/US3539505A/en not_active Expired - Lifetime
-
1974
- 1974-07-19 BE BE146761A patent/BE817880Q/xx active
Also Published As
| Publication number | Publication date |
|---|---|
| AT266049B (de) | 1968-11-11 |
| FI41876B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1969-12-01 |
| DE1598049A1 (de) | 1969-12-11 |
| FI41876C (fi) | 1970-03-10 |
| NL6607638A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1966-12-05 |
| BE817880Q (fr) | 1975-01-20 |
| GB1075920A (en) | 1967-07-19 |
| FR1481755A (fr) | 1967-05-19 |
| US3539505A (en) | 1970-11-10 |
| JPS5110115B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1976-04-01 |
| CH462116A (de) | 1968-09-15 |
| SE338187B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1971-08-30 |
| NL149603B (nl) | 1976-05-17 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| E77 | Valid patent as to the heymanns-index 1977 |