DE1245967B - Verfahren zur Herstellung von S.S-Diamino-o-chlor-pyrazincarbonsäurealkylestern - Google Patents

Verfahren zur Herstellung von S.S-Diamino-o-chlor-pyrazincarbonsäurealkylestern

Info

Publication number
DE1245967B
DE1245967B DENDAT1245967D DE1245967DA DE1245967B DE 1245967 B DE1245967 B DE 1245967B DE NDAT1245967 D DENDAT1245967 D DE NDAT1245967D DE 1245967D A DE1245967D A DE 1245967DA DE 1245967 B DE1245967 B DE 1245967B
Authority
DE
Germany
Prior art keywords
pyrazine
chloro
diamino
carboxylic acid
acid alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
DENDAT1245967D
Other languages
German (de)
English (en)
Inventor
Lansdale Pa. James Holden Jones Blue Bell Pa. Edward Jethro Cragoe jun. (V. St. A.)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Publication date
Publication of DE1245967B publication Critical patent/DE1245967B/de
Pending legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D241/00Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/10Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D241/14Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D241/24Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D241/26Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with nitrogen atoms directly attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
DENDAT1245967D 1964-03-31 Verfahren zur Herstellung von S.S-Diamino-o-chlor-pyrazincarbonsäurealkylestern Pending DE1245967B (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US356038A US3290311A (en) 1964-03-31 1964-03-31 Derivatives of 3, 5-diamino-6-chloropyrazinoic acid esters and a process for making them

Publications (1)

Publication Number Publication Date
DE1245967B true DE1245967B (de) 1967-08-03

Family

ID=23399854

Family Applications (1)

Application Number Title Priority Date Filing Date
DENDAT1245967D Pending DE1245967B (de) 1964-03-31 Verfahren zur Herstellung von S.S-Diamino-o-chlor-pyrazincarbonsäurealkylestern

Country Status (6)

Country Link
US (1) US3290311A (US06262066-20010717-C00359.png)
BE (1) BE653477A (US06262066-20010717-C00359.png)
CH (1) CH488709A (US06262066-20010717-C00359.png)
DE (1) DE1245967B (US06262066-20010717-C00359.png)
FR (1) FR94601E (US06262066-20010717-C00359.png)
NL (1) NL6409712A (US06262066-20010717-C00359.png)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6858615B2 (en) 2002-02-19 2005-02-22 Parion Sciences, Inc. Phenyl guanidine sodium channel blockers
US6903105B2 (en) 2003-02-19 2005-06-07 Parion Sciences, Inc. Sodium channel blockers
AR086745A1 (es) 2011-06-27 2014-01-22 Parion Sciences Inc 3,5-diamino-6-cloro-n-(n-(4-(4-(2-(hexil(2,3,4,5,6-pentahidroxihexil)amino)etoxi)fenil)butil)carbamimidoil)pirazina-2-carboxamida
RU2671976C2 (ru) 2012-12-17 2018-11-08 Пэрион Сайенсиз, Инк. Соединения 3,5-диамино-6-хлор-n-(n-(4-фенилбутил)карбамимидоил)пиразин-2-карбоксамида
CN108484513A (zh) 2012-12-17 2018-09-04 帕里昂科学公司 可用于治疗由黏膜水化不足造成的疾病的氯-吡嗪甲酰胺衍生物
US9102633B2 (en) 2013-12-13 2015-08-11 Parion Sciences, Inc. Arylalkyl- and aryloxyalkyl-substituted epithelial sodium channel blocking compounds
EP3268794A4 (en) 2015-03-13 2019-05-15 Genea IP Holdings Pty Limited METHOD AND DEVICE FOR MICROSCOPY

Also Published As

Publication number Publication date
NL6409712A (US06262066-20010717-C00359.png) 1965-10-01
CH488709A (de) 1970-04-15
FR94601E (fr) 1969-09-19
BE653477A (US06262066-20010717-C00359.png) 1965-03-23
US3290311A (en) 1966-12-06

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