DE1117584B - Verfahren zur Herstellung von Phentiazinderivaten - Google Patents

Verfahren zur Herstellung von Phentiazinderivaten

Info

Publication number
DE1117584B
DE1117584B DES60298A DES0060298A DE1117584B DE 1117584 B DE1117584 B DE 1117584B DE S60298 A DES60298 A DE S60298A DE S0060298 A DES0060298 A DE S0060298A DE 1117584 B DE1117584 B DE 1117584B
Authority
DE
Germany
Prior art keywords
ecm
phenthiazine
benzene
solution
radical
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
DES60298A
Other languages
German (de)
English (en)
Inventor
Robert Michel Jacob
Jacques Georges Robert
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Rhone Poulenc SA
Original Assignee
Rhone Poulenc SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Poulenc SA filed Critical Rhone Poulenc SA
Publication of DE1117584B publication Critical patent/DE1117584B/de
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/36—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems
    • C07D241/38—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems with only hydrogen or carbon atoms directly attached to the ring nitrogen atoms
    • C07D241/40—Benzopyrazines
    • C07D241/44—Benzopyrazines with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D267/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D267/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D267/22—Eight-membered rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Hydrogenated Pyridines (AREA)
DES60298A 1957-10-21 1958-10-17 Verfahren zur Herstellung von Phentiazinderivaten Pending DE1117584B (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR749847 1957-10-21
FR754130A FR73404E (fr) 1957-10-21 1957-12-18 Dérivés de la phénothiazine substitués à l'azote par une chaîne basique comportant un hétérocycle et leur préparation

Publications (1)

Publication Number Publication Date
DE1117584B true DE1117584B (de) 1961-11-23

Family

ID=26183232

Family Applications (1)

Application Number Title Priority Date Filing Date
DES60298A Pending DE1117584B (de) 1957-10-21 1958-10-17 Verfahren zur Herstellung von Phentiazinderivaten

Country Status (10)

Country Link
US (2) US3075976A (enExample)
BE (1) BE572181A (enExample)
BR (1) BR5805969D0 (enExample)
CH (1) CH387636A (enExample)
CY (1) CY320A (enExample)
DE (1) DE1117584B (enExample)
FR (2) FR1212031A (enExample)
GB (2) GB904209A (enExample)
MY (1) MY6500177A (enExample)
NL (1) NL104808C (enExample)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1159954B (de) * 1961-11-25 1963-12-27 Boehringer & Soehne Gmbh Verfahren zur Herstellung neuer 10-(Alkoxypiperidinopropyl)-phenthiazine und ihrer Salze
DE1184765B (de) 1958-07-07 1965-01-07 Sterling Drug Inc Verfahren zur Herstellung von 10-Piperidinoalkylphenthiazinderivaten
WO1998015546A1 (en) * 1996-10-04 1998-04-16 Novo Nordisk A/S N-substituted azaheterocyclic compounds

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1212031A (fr) * 1957-10-21 1960-03-21 Rhone Poulenc Sa Dérivés de la phénothiazine substitués à l'azote par une chaîne basique comportant un hétérocycle et leur préparation
US3193549A (en) * 1958-07-07 1965-07-06 Sterling Drug Inc 10-[(1-piperidyl)lower-alkyl]-trifluoromethylphenothiazines
US3063996A (en) * 1959-03-02 1962-11-13 Smith Kline French Lab Substituted piperidinylalkyl phenothiazines
US3225037A (en) * 1959-03-30 1965-12-21 Sterling Drug Inc 10-[(amino- and acylamino-1-piperidyl) lower-alkyl]-phenothiazines
NL261597A (enExample) * 1960-03-19
NL273878A (enExample) * 1961-01-24
US3183235A (en) * 1961-06-27 1965-05-11 Sterling Drug Inc 1-[3-, 2-, and 1-indolyl-lower-alkanoyl] piperidines
US3879551A (en) * 1967-03-29 1975-04-22 Rhone Poulenc Sa Phenthiazine derivatives in pharmaceutical compositions
FR1558912A (enExample) * 1967-03-29 1969-03-07
CH497458A (de) * 1967-04-19 1970-10-15 Sandoz Ag Verfahren zur Herstellung neuer Phenothiazin-Derivate
US3835319A (en) * 1969-03-27 1974-09-10 Nat Res Corp Cold cathode ion source mass spectrometer with straight line arrangement of ion source and analyzer
US3857943A (en) * 1969-03-27 1974-12-31 May & Baker Ltd New phenothiazine derivatives in the treatment of spasticity of muscles
GB1460713A (en) * 1973-06-08 1977-01-06 Kefalas As 7-fluoro substituted phenothiazines method for preparation thereof and compositions bladed rotor for a gas turbine engine
AR207789A1 (es) * 1974-01-22 1976-10-29 Rhone Poulenc Ind Procedimiento para preparar nuevos esteres derivados de 2-hidroxi-2-dimetilsulfamoil-6-(((hidroxi-2-etil)-4-pipedidino)-3-propil)-10-fenotiazina
FR2290907A2 (fr) * 1974-11-12 1976-06-11 Rhone Poulenc Ind Nouveaux derives de la phenothiazine, leur preparation et les compositions qui les contiennent
GB1517385A (en) * 1975-08-29 1978-07-12 Eisai Co Ltd Phenothiazine derivatives
JPS55111483A (en) * 1979-02-22 1980-08-28 Eisai Co Ltd Novel phenothiazine derivative and psychotropic drug comprising it
US10035795B1 (en) * 2017-04-06 2018-07-31 Korea Institute Of Science And Technology Phenothiazine derivatives having CaM inhibitory activity

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB716230A (en) * 1953-06-29 1954-09-29 Rhone Poulenc Sa New phenthiazine derivatives and processes for their preparation
GB716227A (en) * 1951-02-16 1954-09-29 Rhone Poulenc Sa New phenthiazine derivatives and processes for their production
GB745069A (en) * 1953-04-10 1956-02-22 Rhone Poulenc Sa Improvements in or relating to phenthiazine derivatives and to their production

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2838505A (en) * 1958-06-10 Ocochzchj
US2931810A (en) * 1960-04-05 Phenothiazine derivatives
US2512520A (en) * 1950-06-20 Hydroxyalkylaminoalkyl phenothi
US2534237A (en) * 1950-12-19 B-haloxanthine salts of aminoalkyl
US2272498A (en) * 1939-02-04 1942-02-10 Gen Aniline & Film Corp Process for producing compounds of the diaryl series
US2676971A (en) * 1951-04-21 1954-04-27 Searle & Co Quaternary ammonium derivatives of aminoalkylxanthenes and aminoalkylthiaxanthenes
US2789978A (en) * 1954-07-15 1957-04-23 Rath Stephen Dimethylaminopropyl-dipyridothiazane
US2766135A (en) * 1955-10-21 1956-10-09 Du Pont Method of preparing tricyanovinyl alcohol and heavy metal salts thereof, heavy metalsalts and hydrates of the alcohol and method of using the heavy metal salt as a heat recording coating composition
NL97951C (enExample) * 1955-11-15
NL98215C (enExample) * 1955-11-25
NL108827C (enExample) * 1956-04-09
US2926164A (en) * 1956-08-01 1960-02-23 Searle & Co N-(chlorophenothiazinealkyl)-3 and 4-(hydroxy alkyl)piperidines
BE569430A (enExample) * 1957-07-17
BE561550A (enExample) * 1957-08-23
FR1212031A (fr) * 1957-10-21 1960-03-21 Rhone Poulenc Sa Dérivés de la phénothiazine substitués à l'azote par une chaîne basique comportant un hétérocycle et leur préparation

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB716227A (en) * 1951-02-16 1954-09-29 Rhone Poulenc Sa New phenthiazine derivatives and processes for their production
GB745069A (en) * 1953-04-10 1956-02-22 Rhone Poulenc Sa Improvements in or relating to phenthiazine derivatives and to their production
GB716230A (en) * 1953-06-29 1954-09-29 Rhone Poulenc Sa New phenthiazine derivatives and processes for their preparation

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1184765B (de) 1958-07-07 1965-01-07 Sterling Drug Inc Verfahren zur Herstellung von 10-Piperidinoalkylphenthiazinderivaten
DE1159954B (de) * 1961-11-25 1963-12-27 Boehringer & Soehne Gmbh Verfahren zur Herstellung neuer 10-(Alkoxypiperidinopropyl)-phenthiazine und ihrer Salze
WO1998015546A1 (en) * 1996-10-04 1998-04-16 Novo Nordisk A/S N-substituted azaheterocyclic compounds
US6569849B1 (en) 1996-10-04 2003-05-27 Novo Nordisk A/S N-Substituted azaheterocyclic compounds

Also Published As

Publication number Publication date
GB904208A (en) 1962-08-22
BE572181A (enExample) 1959-04-18
MY6500177A (en) 1965-12-31
CH387636A (fr) 1965-02-15
CY320A (en) 1965-10-18
FR1212031A (fr) 1960-03-21
BR5805969D0 (pt) 1973-05-24
GB904209A (en) 1962-08-22
FR73404E (fr) 1960-07-04
US3075976A (en) 1963-01-29
US3150129A (en) 1964-09-22
NL104808C (enExample) 1963-05-15

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