DE10353202A1 - Pentafluorsulfuranyl-benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament - Google Patents

Pentafluorsulfuranyl-benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament Download PDF

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Publication number
DE10353202A1
DE10353202A1 DE10353202A DE10353202A DE10353202A1 DE 10353202 A1 DE10353202 A1 DE 10353202A1 DE 10353202 A DE10353202 A DE 10353202A DE 10353202 A DE10353202 A DE 10353202A DE 10353202 A1 DE10353202 A1 DE 10353202A1
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Prior art keywords
atoms
zero
alkyl
hydrogen
formula
Prior art date
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DE10353202A
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German (de)
English (en)
Inventor
Heinz-Werner Dr. Kleemann
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis Deutschland GmbH
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Aventis Pharma Deutschland GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
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Priority to OA1200600153A priority Critical patent/OA13285A/en
Application filed by Aventis Pharma Deutschland GmbH filed Critical Aventis Pharma Deutschland GmbH
Priority to DE10353202A priority patent/DE10353202A1/de
Priority to JO2004140A priority patent/JO2466B1/en
Priority to GT200400217A priority patent/GT200400217A/es
Priority to AT04797535T priority patent/ATE368029T1/de
Priority to SI200430424T priority patent/SI1685096T1/sl
Priority to ES04797535T priority patent/ES2287788T3/es
Priority to EP04797535A priority patent/EP1685096B1/de
Priority to UAA200606449A priority patent/UA84307C2/ru
Priority to DE502004004460T priority patent/DE502004004460D1/de
Priority to CNB200480033483XA priority patent/CN100445265C/zh
Priority to HR20070364T priority patent/HRP20070364T3/xx
Priority to JP2006538730A priority patent/JP4528304B2/ja
Priority to BRPI0416487-3A priority patent/BRPI0416487A/pt
Priority to PT04797535T priority patent/PT1685096E/pt
Priority to CA2551057A priority patent/CA2551057C/en
Priority to PCT/EP2004/012393 priority patent/WO2005047239A1/de
Priority to PL04797535T priority patent/PL1685096T3/pl
Priority to HK07102568.1A priority patent/HK1095584B/xx
Priority to RSP-2007/0368A priority patent/RS50520B/sr
Priority to NZ547172A priority patent/NZ547172A/en
Priority to AU2004288758A priority patent/AU2004288758B2/en
Priority to DK04797535T priority patent/DK1685096T3/da
Priority to RU2006120448/04A priority patent/RU2380358C2/ru
Priority to DO2004001028A priority patent/DOP2004001028A/es
Priority to TW093134390A priority patent/TWI334411B/zh
Priority to ARP040104156A priority patent/AR046620A1/es
Priority to HN2004000474A priority patent/HN2004000474A/es
Priority to MYPI20044737A priority patent/MY144211A/en
Priority to PE2004001110A priority patent/PE20051034A1/es
Priority to UY28616A priority patent/UY28616A1/es
Priority to US10/989,069 priority patent/US20050124666A1/en
Publication of DE10353202A1 publication Critical patent/DE10353202A1/de
Priority to ZA200602579A priority patent/ZA200602579B/xx
Priority to CR8321A priority patent/CR8321A/es
Priority to TNP2006000116A priority patent/TNSN06116A1/en
Priority to IL175237A priority patent/IL175237A/en
Priority to EC2006006563A priority patent/ECSP066563A/es
Priority to KR1020067009186A priority patent/KR101262065B1/ko
Priority to NI200600112A priority patent/NI200600112A/es
Priority to MA29028A priority patent/MA28161A1/fr
Priority to NO20062635A priority patent/NO20062635L/no
Priority to CY20071101190T priority patent/CY1106868T1/el
Priority to US11/972,954 priority patent/US7622611B2/en
Withdrawn legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C381/00—Compounds containing carbon and sulfur and having functional groups not covered by groups C07C301/00 - C07C337/00
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    • A61K51/04—Organic compounds
    • A61K51/0404—Lipids, e.g. triglycerides; Polycationic carriers
    • A61K51/0406—Amines, polyamines, e.g. spermine, spermidine, amino acids, (bis)guanidines
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DE10353202A 2003-11-13 2003-11-13 Pentafluorsulfuranyl-benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament Withdrawn DE10353202A1 (de)

Priority Applications (43)

Application Number Priority Date Filing Date Title
OA1200600153A OA13285A (en) 2003-11-13 2003-11-03 Pentafluorosulfanyl benzoylguanidines, method for their production, their use as medicaments or diagnostic agents and medicament containing the same.
DE10353202A DE10353202A1 (de) 2003-11-13 2003-11-13 Pentafluorsulfuranyl-benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament
JO2004140A JO2466B1 (en) 2003-11-13 2004-10-06 Pentaflorosilvanil guanidines, methods of preparation, use as treatment and diagnostic aids, and drugs containing it.
GT200400217A GT200400217A (es) 2003-11-13 2004-10-27 Pentafluorosulfanilbenzoilguanidinas, procedimiento para su preparacion, su uso como medicamento o coadyuvante de diagnostico y medicamento que las comprende.
AU2004288758A AU2004288758B2 (en) 2003-11-13 2004-11-03 Pentafluorosulfanyl benzoylguanidines, method for their production, their use as medicaments or diagnostic agents and medicament containing the same
SI200430424T SI1685096T1 (sl) 2003-11-13 2004-11-03 Pentafluorosulfanil-benzoilgvanidini, postopek zanjihovo pripravo, njihova uporaba kot zdravilo ali diagnostik za zdravilo, ki jih vsebuje
ES04797535T ES2287788T3 (es) 2003-11-13 2004-11-03 Pentafluorosulfanil-benzoilguanidinas, procedimiento para su preparacion, su uso como medicamento o agente de diagnostico, asi como medicamento que las contiene.
EP04797535A EP1685096B1 (de) 2003-11-13 2004-11-03 Pentafluorsulfanyl-benzoylguanidine, verfahren zu ihrer herstellung, ihre verwendung als medikament oder diagnostikum sowie sie enthaltendes medikament
UAA200606449A UA84307C2 (ru) 2003-11-13 2004-11-03 Пентафторсульфанил-бензоилгуанидины, способ их получения, их применение как лекарственных или диагностических средств, а также лекарственные средства, которые их содержат
DE502004004460T DE502004004460D1 (de) 2003-11-13 2004-11-03 Pentafluorsulfanyl-benzoylguanidine, verfahren zu ihrer herstellung, ihre verwendung als medikament oder diagnostikum sowie sie enthaltendes medikament
CNB200480033483XA CN100445265C (zh) 2003-11-13 2004-11-03 五氟硫基苯甲酰基胍、它们的制备方法、它们作为药物或诊断剂的用途和含有它们的药物
HR20070364T HRP20070364T3 (en) 2003-11-13 2004-11-03 Pentafluorosulfanyl benzoylguanidines, method for their production, their use as medicaments or diagnostic agents and medicament containing the same
JP2006538730A JP4528304B2 (ja) 2003-11-13 2004-11-03 ペンタフルオロスルファニルベンゾイルグアニジン、その製造方法、医薬又は診断薬としてのその使用及びそれらを含有する医薬
BRPI0416487-3A BRPI0416487A (pt) 2003-11-13 2004-11-03 pentafluorossulfanil-benzoilguanidinas, método para produção das mesmas, seu uso como medicamentos ou agentes de diagnóstico e medicamento contendo as mesmas
PT04797535T PT1685096E (pt) 2003-11-13 2004-11-03 Pentafluorossulfanil-benzoílguanidinas, processo para a sua preparação, sua utilização como medicamento ou como agente de diagnóstico, bem como medicamento contendo as mesmas
CA2551057A CA2551057C (en) 2003-11-13 2004-11-03 Pentafluorosulfanyl benzoylguanidines, method for their production, their use as medicaments or diagnostic agents and medicament containing the same
PCT/EP2004/012393 WO2005047239A1 (de) 2003-11-13 2004-11-03 Pentafluorsulfanyl-benzoylguanidine, verfahren zu ihrer herstellung, ihre verwendung als medikament oder diagnostikum sowie sie enthaltendes medikament
PL04797535T PL1685096T3 (pl) 2003-11-13 2004-11-03 Pentafluorosulfanylobenzoiloguanidyny, sposób ich wytwarzania, ich zastosowanie jako leku lub środka diagnostycznego, jak również zawierający je lek
HK07102568.1A HK1095584B (en) 2003-11-13 2004-11-03 Pentafluorosulfanyl benzoylguanidines, method for their production, their use as medicaments or diagnostic agents and medicament containing the same
RSP-2007/0368A RS50520B (sr) 2003-11-13 2004-11-03 Pentafluorosulfanil-benzoilgvanidini, postupak za njihovu proizvodnju, njihova primena u svojstvu leka ili dijagnostičkog sredstva kao i lek koji sadrži ova jedinjenja
NZ547172A NZ547172A (en) 2003-11-13 2004-11-03 Pentafluorosulfanyl benzoylguanidines, method for their production, their use as medicaments or diagnostic agents and medicament containing the same
AT04797535T ATE368029T1 (de) 2003-11-13 2004-11-03 Pentafluorsulfanyl-benzoylguanidine, verfahren zu ihrer herstellung, ihre verwendung als medikament oder diagnostikum sowie sie enthaltendes medikament
DK04797535T DK1685096T3 (da) 2003-11-13 2004-11-03 Pentafluorsulfanyl-benzoylguanidiner, fremgangsmåde til deres fremstilling, deres anvendelse som medikament eller diagnostikum såvel som medikamenter indeholdende dem
RU2006120448/04A RU2380358C2 (ru) 2003-11-13 2004-11-03 Пентафторсульфанил-бензоилгуанидины, способ их получения, их применение в качестве лекарственных или диагностических средств, а также содержащие их лекарственные средства
DO2004001028A DOP2004001028A (es) 2003-11-13 2004-11-10 Pentafluorosulfanilbenzoilguanidinas, procedimiento para su preparacion, su uso como medicamento o coadyuvante de diagnostico, y medicamento que las comprende
TW093134390A TWI334411B (en) 2003-11-13 2004-11-11 Pentafluorosulfanylbenzoylguanidines, process for their preparation, their use as medicament or diagnostic aid, and medicament comprising them
HN2004000474A HN2004000474A (es) 2003-11-13 2004-11-11 Pentafluorosulfanilbenzoilguanidinas y sus sales farmaceuticamente aceptables son acilguanidinas sustituidas e inhiben el antiportador celular de sodioprotones ( intercambiador na + / , nhe )
ARP040104156A AR046620A1 (es) 2003-11-13 2004-11-11 Pentafluorosulfanilbenzoilguanidinas, procedimiento para su preparacion, su uso como medicamento o coadyuvante de diagnostico, y medicamento que las comprende
MYPI20044737A MY144211A (en) 2003-11-13 2004-11-12 Pentafluorosulfanylbenzoylguanidines, process for their preparation, their use as medicament or diagnostic aid, and medicament comprising them
PE2004001110A PE20051034A1 (es) 2003-11-13 2004-11-12 Pentafluorosulfanilbenzoilguanidinas como inhibidores del antiportador celular de sodio-protones (nhe)
UY28616A UY28616A1 (es) 2003-11-13 2004-11-12 Pentafluorosulfanilbenzoilguanidinas, procedimiento para su preparación, su uso como medicamento o coadyuvante de diagnostico, y medicamento que las comprende.
US10/989,069 US20050124666A1 (en) 2003-11-13 2004-11-15 Pentafluorosulfanylbenzoylguanidines, process for their preparation, use as a medicament or diagnostic aid, and medicament comprising same
ZA200602579A ZA200602579B (en) 2003-11-13 2006-03-29 Pentafluorosulfanyl, benzoylguanidines, method for their production, their use as medicaments or diagnostic agents and medicament containing the same
CR8321A CR8321A (es) 2003-11-13 2006-03-31 Pentafluorosulfanil benzoylguanidinas, metodo para su produccion, su uso como medicamentos o agentes de diagnostico, y medicamento que las contiene
TNP2006000116A TNSN06116A1 (en) 2003-11-13 2006-04-21 Pentafluorosulfanyl benzoylguanidines, method for their production, their use as medicaments or diagnostic agents and medicament containing the same
IL175237A IL175237A (en) 2003-11-13 2006-04-26 Pentafluorosulfanyl benzoylguanidines, method for their production, their use as medicaments and medicaments containing the same
EC2006006563A ECSP066563A (es) 2003-11-13 2006-05-11 Pentafluorosulfanil-benzoilguanidinas, método para su producción, su uso como medicamentos o agentes de diagnóstico, y medicamento que las contiene
KR1020067009186A KR101262065B1 (ko) 2003-11-13 2006-05-11 펜타플루오로설파닐 벤조일구아니딘, 이의 제조방법, 약물또는 진단제로서의 이의 용도 및 이를 포함하는 약물
NI200600112A NI200600112A (es) 2003-11-13 2006-05-12 Pentafluorosulfanil-benzoilguanidinas, metodo para su produccion, su uso como medicamentos o agentes de diagnostico, y medicamento que las contiene.
MA29028A MA28161A1 (fr) 2003-11-13 2006-05-12 Les pentafluorosulfanylbenzoylguanidines, leur procédé de production, leur utilisation comme médicaments ou agents de diagnostic et les médicaments les contenant
NO20062635A NO20062635L (no) 2003-11-13 2006-06-08 Pentafluorsulfanyl-benzoylguanidiner, produksjonsmetode, deres anvendelse som medikamenter eller diagnostiserende midler og medikamenter inneholdende disse
CY20071101190T CY1106868T1 (el) 2003-11-13 2007-09-14 Πενταφθοροσουλφανυλο-βενζοϋλογουανιδινες, μεθοδος για την παρασκευη τους, η χρηση τους ως φαρμακο ή διαγνωστικο μεσο, ως και φαρμακο που τις περιεχει
US11/972,954 US7622611B2 (en) 2003-11-13 2008-01-11 Pentafluorosulfanylbenzoylguanidines, process for their preparation, use as a medicament or diagnostic aid, and medicament comprising same

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US8937088B2 (en) * 2011-01-06 2015-01-20 Astar Biotech Llc Ureas for the treatment and prevention of cancer
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IL175237A0 (en) 2006-09-05
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KR101262065B1 (ko) 2013-05-08
WO2005047239A1 (de) 2005-05-26
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PL1685096T3 (pl) 2007-11-30
OA13285A (en) 2007-01-31
JP2007513076A (ja) 2007-05-24
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JP4528304B2 (ja) 2010-08-18
ES2287788T3 (es) 2007-12-16
MY144211A (en) 2011-08-15
EP1685096B1 (de) 2007-07-25
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