DE10333393A1 - Transdermales Therapeutisches System mit dem Wirkstoff Pramipexol - Google Patents
Transdermales Therapeutisches System mit dem Wirkstoff Pramipexol Download PDFInfo
- Publication number
- DE10333393A1 DE10333393A1 DE10333393A DE10333393A DE10333393A1 DE 10333393 A1 DE10333393 A1 DE 10333393A1 DE 10333393 A DE10333393 A DE 10333393A DE 10333393 A DE10333393 A DE 10333393A DE 10333393 A1 DE10333393 A1 DE 10333393A1
- Authority
- DE
- Germany
- Prior art keywords
- pramipexole
- tts
- active substance
- tts according
- obesity
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
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Classifications
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- A—HUMAN NECESSITIES
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- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
- A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
- A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
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- A—HUMAN NECESSITIES
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/428—Thiazoles condensed with carbocyclic rings
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/04—Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P25/24—Antidepressants
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- A—HUMAN NECESSITIES
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- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
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- Hematology (AREA)
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- Endocrinology (AREA)
- Pain & Pain Management (AREA)
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- Emergency Medicine (AREA)
- Child & Adolescent Psychology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
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- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (12)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10333393A DE10333393A1 (de) | 2003-07-23 | 2003-07-23 | Transdermales Therapeutisches System mit dem Wirkstoff Pramipexol |
| CNB2004800210396A CN100450482C (zh) | 2003-07-23 | 2004-07-14 | 含有普拉克索活性剂的透皮治疗系统 |
| US10/564,932 US20060182791A1 (en) | 2003-07-23 | 2004-07-14 | Transdermaltherapeutic system containing a pramipexol active agent |
| JP2006520736A JP4925823B2 (ja) | 2003-07-23 | 2004-07-14 | プラミペキソール活性剤を含む経皮治療システム |
| AU2004260583A AU2004260583B2 (en) | 2003-07-23 | 2004-07-14 | Transdermaltherapeutic system containing a pramipexol active agent |
| CA002532904A CA2532904A1 (en) | 2003-07-23 | 2004-07-14 | Transdermal therapeutic system containing a pramipexol active agent |
| KR1020067001495A KR20060113638A (ko) | 2003-07-23 | 2004-07-14 | 프라미펙솔 활성 제제를 함유하는 경피치료 시스템 |
| BRPI0412240-2A BRPI0412240A (pt) | 2003-07-23 | 2004-07-14 | sistema terapêutico transdérmico com a substáncia ativa pramipexol |
| EP04740987A EP1651215A1 (de) | 2003-07-23 | 2004-07-14 | Transdermales therapeutisches system mit dem wirkstoff pramipexol |
| PCT/EP2004/007770 WO2005011687A1 (de) | 2003-07-23 | 2004-07-14 | Transdermales therapeutisches system mit dem wirkstoff pramipexol |
| ZA200600206A ZA200600206B (en) | 2003-07-23 | 2006-01-09 | Transdermaltherapeutic system containing a pramipexol active agent |
| US13/473,724 US20120225103A1 (en) | 2003-07-23 | 2012-05-17 | Transdermal Therapeutic System Containing a Pramipexol Active Agent |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10333393A DE10333393A1 (de) | 2003-07-23 | 2003-07-23 | Transdermales Therapeutisches System mit dem Wirkstoff Pramipexol |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE10333393A1 true DE10333393A1 (de) | 2005-02-24 |
Family
ID=34088745
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE10333393A Ceased DE10333393A1 (de) | 2003-07-23 | 2003-07-23 | Transdermales Therapeutisches System mit dem Wirkstoff Pramipexol |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US20060182791A1 (enExample) |
| EP (1) | EP1651215A1 (enExample) |
| JP (1) | JP4925823B2 (enExample) |
| KR (1) | KR20060113638A (enExample) |
| CN (1) | CN100450482C (enExample) |
| AU (1) | AU2004260583B2 (enExample) |
| BR (1) | BRPI0412240A (enExample) |
| CA (1) | CA2532904A1 (enExample) |
| DE (1) | DE10333393A1 (enExample) |
| WO (1) | WO2005011687A1 (enExample) |
| ZA (1) | ZA200600206B (enExample) |
Families Citing this family (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2619217A1 (en) * | 2005-08-15 | 2007-02-22 | University Of Virginia Patent Foundation | Neurorestoration with r(+) pramipexole |
| US8518926B2 (en) | 2006-04-10 | 2013-08-27 | Knopp Neurosciences, Inc. | Compositions and methods of using (R)-pramipexole |
| CN101448498B (zh) | 2006-05-16 | 2011-04-27 | 诺普神经科学股份有限公司 | R(+)和s(-)普拉克索的组合物以及使用该组合物的方法 |
| WO2008001200A2 (en) * | 2006-06-29 | 2008-01-03 | Antares Pharma Ipl Ag | Transdermal composition having enhanced color stability |
| US20080254118A1 (en) * | 2007-04-11 | 2008-10-16 | Hans-Werner Wernersbach | Process for preparing pramipexole dihydrochloride tablets |
| US8524695B2 (en) | 2006-12-14 | 2013-09-03 | Knopp Neurosciences, Inc. | Modified release formulations of (6R)-4,5,6,7-tetrahydro-N6-propyl-2,6-benzothiazole-diamine and methods of using the same |
| EP2136638A4 (en) * | 2007-03-14 | 2010-05-12 | Knopp Neurosciences Inc | MODIFIED RELEASE FORMULATIONS OF (6R) -4,5,6,7-TETRAHYDRO-N6-PROPYL-2,6-BENZOTHIAZOLE DIAMINE AND METHODS OF USE THEREOF |
| CA2681110A1 (en) | 2007-03-14 | 2008-09-18 | Knopp Neurosciences, Inc. | Synthesis of chirally purified substituted benzothiazole diamines |
| US20080254117A1 (en) * | 2007-04-10 | 2008-10-16 | Noel Cotton | Process for preparing pramipexole dihydrochloride tablets |
| WO2010010141A1 (en) * | 2008-07-25 | 2010-01-28 | Boehringer Ingelheim International Gmbh | Pramipexole for treating cardiomyopathy |
| KR20110071064A (ko) | 2008-08-19 | 2011-06-28 | 크놉 뉴로사이언시스 인코포레이티드 | (ｒ)-프라미펙솔을 사용하는 조성물 및 방법 |
| JP5652867B2 (ja) * | 2009-11-20 | 2015-01-14 | 日東電工株式会社 | 医療用粘着剤組成物 |
| JP5665116B2 (ja) * | 2009-11-20 | 2015-02-04 | 日東電工株式会社 | 貼付剤および貼付製剤 |
| WO2013096816A1 (en) | 2011-12-22 | 2013-06-27 | Biogen Idec Ma Inc. | Improved synthesis of amine substituted 4,5,6,7-tetrahydrobenzothiazole compounds |
| DE102012205493A1 (de) | 2012-04-03 | 2013-10-10 | Acino Ag | Einen Dopamin-Agonisten enthaltendes transdermales Applikationssystem |
| US20140045801A1 (en) * | 2012-08-09 | 2014-02-13 | Mylan Inc. | Pramipexole transdermal delivery for severe headaches |
| US9662313B2 (en) | 2013-02-28 | 2017-05-30 | Knopp Biosciences Llc | Compositions and methods for treating amyotrophic lateral sclerosis in responders |
| WO2014188329A2 (en) * | 2013-05-20 | 2014-11-27 | Mylan, Inc. | Transdermal therapeutic system for extended dosing of pramipexole in treating neurological disorders |
| US9468630B2 (en) | 2013-07-12 | 2016-10-18 | Knopp Biosciences Llc | Compositions and methods for treating conditions related to increased eosinophils |
| PL3019167T3 (pl) | 2013-07-12 | 2021-06-14 | Knopp Biosciences Llc | Leczenie podwyższonych poziomów eozynofili i/lub bazofili |
| CA2921378A1 (en) | 2013-08-13 | 2015-02-19 | Knopp Biosciences Llc | Compositions and methods for treating plasma cell disorders and b-cell prolymphocytic disorders |
| US9763918B2 (en) | 2013-08-13 | 2017-09-19 | Knopp Biosciences Llc | Compositions and methods for treating chronic urticaria |
| CN103610666A (zh) * | 2013-12-11 | 2014-03-05 | 中国药科大学 | 一种盐酸普拉克索透皮贴剂及其制备方法 |
| EP3111935A4 (en) | 2014-02-27 | 2017-03-15 | Medrx Co., Ltd. | Pramipexole-containing transdermal patch for treatment of neurodegenerative disease |
| US9837244B2 (en) * | 2014-12-26 | 2017-12-05 | Industrial Technology Research Insitute | Sample holding device for studying light-driven reactions and sample analysis method using the same |
| CN104510725B (zh) * | 2015-01-22 | 2021-04-27 | 中国药科大学 | 一种普拉克索周效透皮贴剂及其制备方法 |
| WO2018067163A1 (en) * | 2016-10-07 | 2018-04-12 | Transwell Biotech Co., Ltd. | Pramipexole transdermal delivery system and uses thereof |
| CN109999012A (zh) * | 2019-03-26 | 2019-07-12 | 大道隆达（北京）医药科技发展有限公司 | 一种普拉克索透皮贴剂及其制备方法 |
| CN111904950B (zh) * | 2019-05-07 | 2023-05-05 | 上海京新生物医药有限公司 | 一种普拉克索透皮贴剂 |
| CN117860708A (zh) * | 2022-10-11 | 2024-04-12 | 姜钦治 | 含有普拉克索和雷沙吉兰的透皮贴片 |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10137082A1 (de) * | 2001-07-28 | 2003-02-13 | Hexal Ag | Matrixkontrolliertes transdermales therapeutisches System zur Anwendung von Pramiprexol und Ropinirol |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3315272C2 (de) * | 1983-04-27 | 1986-03-27 | Lohmann Gmbh & Co Kg, 5450 Neuwied | Pharmazeutisches Produkt und Verfahren zu seiner Herstellung |
| US5238944A (en) * | 1988-12-15 | 1993-08-24 | Riker Laboratories, Inc. | Topical formulations and transdermal delivery systems containing 1-isobutyl-1H-imidazo[4,5-c]quinolin-4-amine |
| DE3937271A1 (de) * | 1989-11-09 | 1991-05-16 | Boehringer Ingelheim Kg | Transdermale applikation von 2-amino-6-n-propylamino-4,5,6,7-tetrahydrobenzothiazol |
| US5650420A (en) * | 1994-12-15 | 1997-07-22 | Pharmacia & Upjohn Company | Pramipexole as a neuroprotective agent |
| US5562917A (en) * | 1994-12-23 | 1996-10-08 | Pentech Pharmaceuticals, Inc. | Transdermal administration of apomorphine |
| AU6032696A (en) * | 1995-06-07 | 1996-12-30 | Cygnus Therapeutic Systems | Pressure sensitive acrylate adhesive composition cross-linke d with aluminum acetylacetonate and containing a drug having a reactive aromatic hydroxyl group |
| US6365178B1 (en) * | 1996-09-06 | 2002-04-02 | Watson Pharmaceuticals, Inc. | Method of making pressure sensitive adhesive matrix patches for transdermal drug delivery using hydrophilic salts of drugs and hydrophobic pressure sensitive adhesive dispersions |
| AU5325000A (en) * | 1999-06-05 | 2000-12-28 | David Houze | Solubility enhancement of drugs in transdermal drug delivery systems and methodsof use |
| NZ518436A (en) * | 1999-10-28 | 2002-11-26 | 3M Innovative Properties Co | Transdermal drug delivery devices |
| DE10033853A1 (de) * | 2000-07-12 | 2002-01-31 | Hexal Ag | Transdermales therapeutisches System mit hochdispersem Siliziumdioxid |
| EP1366762B1 (en) * | 2001-03-07 | 2015-12-30 | Hisamitsu Pharmaceutical Co., Inc. | Adhesive patch |
| DE10137162A1 (de) * | 2001-07-30 | 2003-02-20 | Hexal Ag | Matrixkontrolliertes transdermales therapeutisches System zur Anwendung von Pramiprexol und Ropinirol |
-
2003
- 2003-07-23 DE DE10333393A patent/DE10333393A1/de not_active Ceased
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2004
- 2004-07-14 AU AU2004260583A patent/AU2004260583B2/en not_active Ceased
- 2004-07-14 CA CA002532904A patent/CA2532904A1/en not_active Abandoned
- 2004-07-14 BR BRPI0412240-2A patent/BRPI0412240A/pt not_active IP Right Cessation
- 2004-07-14 WO PCT/EP2004/007770 patent/WO2005011687A1/de not_active Ceased
- 2004-07-14 KR KR1020067001495A patent/KR20060113638A/ko not_active Ceased
- 2004-07-14 JP JP2006520736A patent/JP4925823B2/ja not_active Expired - Fee Related
- 2004-07-14 CN CNB2004800210396A patent/CN100450482C/zh not_active Expired - Fee Related
- 2004-07-14 US US10/564,932 patent/US20060182791A1/en not_active Abandoned
- 2004-07-14 EP EP04740987A patent/EP1651215A1/de not_active Withdrawn
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2006
- 2006-01-09 ZA ZA200600206A patent/ZA200600206B/en unknown
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2012
- 2012-05-17 US US13/473,724 patent/US20120225103A1/en not_active Abandoned
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10137082A1 (de) * | 2001-07-28 | 2003-02-13 | Hexal Ag | Matrixkontrolliertes transdermales therapeutisches System zur Anwendung von Pramiprexol und Ropinirol |
Also Published As
| Publication number | Publication date |
|---|---|
| CN100450482C (zh) | 2009-01-14 |
| BRPI0412240A (pt) | 2006-09-12 |
| WO2005011687A1 (de) | 2005-02-10 |
| JP2006528144A (ja) | 2006-12-14 |
| AU2004260583B2 (en) | 2010-01-28 |
| AU2004260583A1 (en) | 2005-02-10 |
| US20120225103A1 (en) | 2012-09-06 |
| JP4925823B2 (ja) | 2012-05-09 |
| EP1651215A1 (de) | 2006-05-03 |
| KR20060113638A (ko) | 2006-11-02 |
| US20060182791A1 (en) | 2006-08-17 |
| ZA200600206B (en) | 2007-02-28 |
| CA2532904A1 (en) | 2005-02-10 |
| CN1826113A (zh) | 2006-08-30 |
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Effective date: 20130328 |