DE10301421A1 - Prozessanalysensysteme mit automatischer Flüssigprobenvorbereitung und Anbindung zu Prozessleitsystemen - Google Patents
Prozessanalysensysteme mit automatischer Flüssigprobenvorbereitung und Anbindung zu Prozessleitsystemen Download PDFInfo
- Publication number
- DE10301421A1 DE10301421A1 DE10301421A DE10301421A DE10301421A1 DE 10301421 A1 DE10301421 A1 DE 10301421A1 DE 10301421 A DE10301421 A DE 10301421A DE 10301421 A DE10301421 A DE 10301421A DE 10301421 A1 DE10301421 A1 DE 10301421A1
- Authority
- DE
- Germany
- Prior art keywords
- sample preparation
- sample
- control
- analysis
- modules
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 238000002360 preparation method Methods 0.000 title claims abstract description 82
- 238000004458 analytical method Methods 0.000 title claims abstract description 58
- 238000000034 method Methods 0.000 title claims abstract description 53
- 230000008569 process Effects 0.000 title claims abstract description 49
- 238000004886 process control Methods 0.000 title claims abstract description 24
- 239000007788 liquid Substances 0.000 title claims description 8
- 230000009471 action Effects 0.000 claims description 8
- 230000001276 controlling effect Effects 0.000 claims description 8
- 238000005070 sampling Methods 0.000 claims description 8
- 238000004590 computer program Methods 0.000 claims description 6
- 238000012546 transfer Methods 0.000 claims description 5
- 230000001105 regulatory effect Effects 0.000 claims description 2
- 230000005540 biological transmission Effects 0.000 claims 2
- 238000002290 gas chromatography-mass spectrometry Methods 0.000 claims 1
- 238000000589 high-performance liquid chromatography-mass spectrometry Methods 0.000 claims 1
- 239000000126 substance Substances 0.000 description 12
- 238000010790 dilution Methods 0.000 description 5
- 239000012895 dilution Substances 0.000 description 5
- 238000004587 chromatography analysis Methods 0.000 description 4
- 238000001212 derivatisation Methods 0.000 description 4
- 238000002347 injection Methods 0.000 description 4
- 239000007924 injection Substances 0.000 description 4
- 230000008901 benefit Effects 0.000 description 3
- 238000010586 diagram Methods 0.000 description 3
- 238000001914 filtration Methods 0.000 description 3
- 239000002904 solvent Substances 0.000 description 3
- 238000007792 addition Methods 0.000 description 2
- 238000013528 artificial neural network Methods 0.000 description 2
- 150000001875 compounds Chemical class 0.000 description 2
- 239000004615 ingredient Substances 0.000 description 2
- 238000002156 mixing Methods 0.000 description 2
- 239000002699 waste material Substances 0.000 description 2
- 238000004497 NIR spectroscopy Methods 0.000 description 1
- 238000001069 Raman spectroscopy Methods 0.000 description 1
- 230000004913 activation Effects 0.000 description 1
- 239000012482 calibration solution Substances 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 239000003153 chemical reaction reagent Substances 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 238000001816 cooling Methods 0.000 description 1
- 230000008878 coupling Effects 0.000 description 1
- 238000010168 coupling process Methods 0.000 description 1
- 238000005859 coupling reaction Methods 0.000 description 1
- 238000000354 decomposition reaction Methods 0.000 description 1
- 230000001419 dependent effect Effects 0.000 description 1
- 238000013461 design Methods 0.000 description 1
- 238000011156 evaluation Methods 0.000 description 1
- 239000000284 extract Substances 0.000 description 1
- 238000000605 extraction Methods 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 230000010354 integration Effects 0.000 description 1
- 239000013067 intermediate product Substances 0.000 description 1
- -1 internal standards Substances 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 238000010327 methods by industry Methods 0.000 description 1
- 230000003287 optical effect Effects 0.000 description 1
- 150000008442 polyphenolic compounds Chemical class 0.000 description 1
- 239000000047 product Substances 0.000 description 1
- 238000000746 purification Methods 0.000 description 1
- 238000001226 reprecipitation Methods 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
- 235000020046 sherry Nutrition 0.000 description 1
- 238000006884 silylation reaction Methods 0.000 description 1
- 238000011003 system suitability test Methods 0.000 description 1
- 238000005496 tempering Methods 0.000 description 1
- 238000011144 upstream manufacturing Methods 0.000 description 1
- 239000002351 wastewater Substances 0.000 description 1
- 235000014101 wine Nutrition 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/88—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/00584—Control arrangements for automatic analysers
-
- G—PHYSICS
- G05—CONTROLLING; REGULATING
- G05D—SYSTEMS FOR CONTROLLING OR REGULATING NON-ELECTRIC VARIABLES
- G05D21/00—Control of chemical or physico-chemical variables, e.g. pH value
- G05D21/02—Control of chemical or physico-chemical variables, e.g. pH value characterised by the use of electric means
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/88—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86
- G01N2030/8804—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86 automated systems
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/88—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86
- G01N2030/8886—Analysis of industrial production processes
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N2035/00178—Special arrangements of analysers
- G01N2035/00326—Analysers with modular structure
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/00584—Control arrangements for automatic analysers
- G01N35/00722—Communications; Identification
- G01N2035/00891—Displaying information to the operator
- G01N2035/0091—GUI [graphical user interfaces]
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/04—Preparation or injection of sample to be analysed
- G01N30/16—Injection
- G01N30/20—Injection using a sampling valve
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/86—Signal analysis
- G01N30/8651—Recording, data aquisition, archiving and storage
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/00584—Control arrangements for automatic analysers
- G01N35/00722—Communications; Identification
- G01N35/00871—Communications between instruments or with remote terminals
Landscapes
- Physics & Mathematics (AREA)
- General Physics & Mathematics (AREA)
- General Health & Medical Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Automation & Control Theory (AREA)
- Engineering & Computer Science (AREA)
- Sampling And Sample Adjustment (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
- Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
Priority Applications (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10301421A DE10301421A1 (de) | 2003-01-16 | 2003-01-16 | Prozessanalysensysteme mit automatischer Flüssigprobenvorbereitung und Anbindung zu Prozessleitsystemen |
| DK04000198.4T DK1439472T3 (en) | 2003-01-16 | 2004-01-08 | Process analysis systems with automatic liquid sample preparation and connection to process control systems |
| EP04000198.4A EP1439472B1 (de) | 2003-01-16 | 2004-01-08 | Prozessanalysensysteme mit automatischer Flüssigprobenvorbereitung und Anbindung zu Prozessleitsystemen |
| US10/755,754 US20040158433A1 (en) | 2003-01-16 | 2004-01-12 | Process analysis systems with automatic liquid sample preparation and connection to process control systems |
| CN201210359986.2A CN102928541B (zh) | 2003-01-16 | 2004-01-16 | 具有自动化液样准备的过程分析系统及过程控制方法 |
| CNA2004100059020A CN1517711A (zh) | 2003-01-16 | 2004-01-16 | 具有自动化液样准备的过程分析系统及其与过程控制系统的连接 |
| JP2004008803A JP2004226402A (ja) | 2003-01-16 | 2004-01-16 | 自動液体サンプル調製を備えるプロセスコントロールシステムに接続されたプロセス分析システム |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10301421A DE10301421A1 (de) | 2003-01-16 | 2003-01-16 | Prozessanalysensysteme mit automatischer Flüssigprobenvorbereitung und Anbindung zu Prozessleitsystemen |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE10301421A1 true DE10301421A1 (de) | 2004-07-29 |
Family
ID=32519994
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE10301421A Withdrawn DE10301421A1 (de) | 2003-01-16 | 2003-01-16 | Prozessanalysensysteme mit automatischer Flüssigprobenvorbereitung und Anbindung zu Prozessleitsystemen |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20040158433A1 (enExample) |
| EP (1) | EP1439472B1 (enExample) |
| JP (1) | JP2004226402A (enExample) |
| CN (2) | CN102928541B (enExample) |
| DE (1) | DE10301421A1 (enExample) |
| DK (1) | DK1439472T3 (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE102010044283A1 (de) * | 2010-09-03 | 2012-03-08 | M04 Tech Ug (Haftungsbeschränkt) | Vorrichtung und Verfahren zur Analyse biologischer Proben |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7074327B2 (en) * | 2003-05-08 | 2006-07-11 | Nanostream, Inc. | Sample preparation for parallel chromatography |
| JP2006105800A (ja) * | 2004-10-06 | 2006-04-20 | Shimadzu Corp | 分析システム、該システムに用いる情報集合体、及び該情報集合体を格納した記録媒体 |
| DE102006019242A1 (de) | 2006-04-21 | 2007-10-25 | Bayer Technology Services Gmbh | Prozessanalysensystem mit steriler Probenahme von mechanisch empfindlichem Material aus einem Bioreaktor |
| US7610151B2 (en) | 2006-06-27 | 2009-10-27 | Microsoft Corporation | Collaborative route planning for generating personalized and context-sensitive routing recommendations |
| US8060297B2 (en) * | 2007-12-14 | 2011-11-15 | Microsoft Corporation | Route transfer between devices |
| US8090532B2 (en) * | 2007-12-14 | 2012-01-03 | Microsoft Corporation | Pedestrian route production |
| US8473198B2 (en) * | 2007-12-14 | 2013-06-25 | Microsoft Corporation | Additional content based on intended travel destination |
| US20090157499A1 (en) * | 2007-12-14 | 2009-06-18 | Microsoft Corporation | Automatic splices for targeted advertisements |
| US8428859B2 (en) * | 2007-12-14 | 2013-04-23 | Microsoft Corporation | Federated route production |
| CN105911196B (zh) | 2010-10-29 | 2019-04-23 | 恩姆菲舍尔科技公司 | 用于样品制备和分析的自动化系统的系统布局 |
| JP6126012B2 (ja) | 2010-12-17 | 2017-05-10 | エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft | 定量試料分析のための分離および検出処理の複数の装置の自動制御 |
| WO2012165229A1 (ja) | 2011-06-03 | 2012-12-06 | 株式会社日立ハイテクノロジーズ | 自動分析装置 |
| US8800352B2 (en) * | 2011-07-15 | 2014-08-12 | Thermo Finnigan Llc | Method for automatic optimization of liquid chromatography autosampler |
| EP2570167A1 (de) | 2011-09-13 | 2013-03-20 | Bayer Intellectual Property GmbH | Gerät und Verfahren zur diskontinuierlichen Filtration |
| US9182886B2 (en) * | 2011-11-14 | 2015-11-10 | Bio-Rad Laboratories Inc. | Chromatography configuration interface |
| US9275198B2 (en) * | 2011-12-06 | 2016-03-01 | The Boeing Company | Systems and methods for electronically publishing content |
| CN104812888A (zh) | 2012-09-18 | 2015-07-29 | 拜耳技术服务有限公司 | 一次性瓶式反应罐 |
| EP2713166B1 (de) | 2012-10-01 | 2019-05-22 | Eppendorf Ag | Laborautomat und Verfahren zur automatischen Behandlung von Laborproben |
| JP6581786B2 (ja) * | 2015-03-18 | 2019-09-25 | 株式会社日立ハイテクソリューションズ | 薬物探知装置 |
| WO2016157516A1 (ja) * | 2015-04-03 | 2016-10-06 | 株式会社島津製作所 | モジュラー型分析システム |
| DE102015106258A1 (de) * | 2015-04-23 | 2016-10-27 | Khs Gmbh | Verfahren und Vorrichtung zur Stabilisierung polyphenolhaltiger Flüssigkeiten |
| CN105571907B (zh) * | 2016-01-24 | 2019-08-20 | 浙江永宁药业股份有限公司 | 液体排放与分时段采样设备 |
| JP7057912B2 (ja) * | 2017-04-14 | 2022-04-21 | 次世代バイオ医薬品製造技術研究組合 | タンパク質の分離精製方法および装置 |
| CN110131783B (zh) * | 2019-05-15 | 2020-01-07 | 北京市众诚恒祥能源投资管理有限公司 | 一种高效节能集中供热自动化控制装置 |
| JP2021189000A (ja) * | 2020-05-28 | 2021-12-13 | 株式会社島津製作所 | 分析装置選択装置および分析装置選択方法 |
| US20240201658A1 (en) * | 2021-04-22 | 2024-06-20 | Shimadzu Corporation | Monitoring system and monitoring method |
Family Cites Families (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2039755A1 (de) * | 1970-01-05 | 1972-02-03 | Petrolchemisches Kombinat | Verfahren und Einrichtungen zur Steuerung von Gaschromatographen und Auswertung von Gaschromatogrammen,insbesondere fuer Regleranschluss geeignet |
| US4657390A (en) * | 1985-02-21 | 1987-04-14 | Laser Precision Corporation | Universal spectrometer system having modular sampling chamber |
| GB8601338D0 (en) * | 1986-01-21 | 1986-02-26 | Imp Group Plc | Chemical analysis system |
| FR2597980B1 (fr) * | 1986-04-25 | 1990-11-16 | Rhone Poulenc Rech | Procede et installation d'analyse en ligne d'un produit liquide par chromatographie en phase liquide |
| US4722830A (en) * | 1986-05-05 | 1988-02-02 | General Electric Company | Automated multiple stream analysis system |
| US4835711A (en) * | 1986-05-30 | 1989-05-30 | Zymark Corporation | Quickly reconfigurable robotic system |
| EP0255026A3 (en) * | 1986-07-23 | 1988-10-19 | Takeda Chemical Industries, Ltd. | Automatic analysis method and apparatus for enzyme reaction |
| ATE150879T1 (de) * | 1989-10-17 | 1997-04-15 | Perkin Elmer Corp | Robotische schnittstelle |
| US5222032A (en) * | 1990-10-26 | 1993-06-22 | E. I. Du Pont De Nemours And Company | System and method for monitoring the concentration of volatile material dissolved in a liquid |
| DE69216258T2 (de) * | 1991-02-15 | 1997-07-17 | Yamatake Honeywell Co Ltd | Gaschromatographisches System zur Analyse von Abgasen |
| EP0596205A3 (en) * | 1992-11-03 | 1996-02-21 | Hewlett Packard Co | Bench supervisor system. |
| US5541831A (en) * | 1993-04-16 | 1996-07-30 | Oliver Manufacturing Co., Inc. | Computer controlled separator device |
| EP0640833A1 (en) * | 1993-08-31 | 1995-03-01 | R.J. Reynolds Tobacco Company | Method and apparatus for continuous emissions monitoring system using gas chromatography |
| US5576946A (en) * | 1993-09-30 | 1996-11-19 | Fluid Air, Inc. | Icon based process design and control system |
| US5464504A (en) * | 1993-12-02 | 1995-11-07 | Phillips Petroleum Company | Inferential correction of composition for a distillation analyzer |
| CN1067599C (zh) * | 1995-11-30 | 2001-06-27 | 上海跃龙有色金属有限公司 | 溶剂萃取过程的自动控制系统和方法 |
| CN1249036A (zh) * | 1997-03-11 | 2000-03-29 | 菲舍尔分析仪器有限公司 | 碳同位素分析仪 |
| US6007235A (en) * | 1998-02-25 | 1999-12-28 | Honeywell Inc. | Sampling and diluting system for particle size distribution measurement |
| US6020960A (en) * | 1998-02-25 | 2000-02-01 | Honeywell Inc. | System for the in-line extraction and dilution of a representative sample of a processed medium |
| EP0997800B1 (de) * | 1998-10-29 | 2002-07-24 | Endress + Hauser GmbH + Co. KG | Gerät zur Verwendung in einem industriellen Prozess und Anlage mit solchen Geräten sowie Verfahren zum Simulieren des Betriebs einer solchen Anlage |
| JP4105348B2 (ja) * | 1999-11-19 | 2008-06-25 | 株式会社日立製作所 | 試料分析用モニタ装置及びそれを用いた燃焼制御システム |
| US6650957B1 (en) * | 2000-01-03 | 2003-11-18 | Advanced Micro Devices, Inc. | Method and apparatus for run-to-run control of deposition process |
| US7220383B2 (en) * | 2001-07-13 | 2007-05-22 | Metara, Inc. | Method and instrument for automated analysis of fluid-based processing systems |
| US7153362B2 (en) * | 2002-04-30 | 2006-12-26 | Samsung Electronics Co., Ltd. | System and method for real time deposition process control based on resulting product detection |
-
2003
- 2003-01-16 DE DE10301421A patent/DE10301421A1/de not_active Withdrawn
-
2004
- 2004-01-08 EP EP04000198.4A patent/EP1439472B1/de not_active Expired - Lifetime
- 2004-01-08 DK DK04000198.4T patent/DK1439472T3/en active
- 2004-01-12 US US10/755,754 patent/US20040158433A1/en not_active Abandoned
- 2004-01-16 CN CN201210359986.2A patent/CN102928541B/zh not_active Expired - Fee Related
- 2004-01-16 CN CNA2004100059020A patent/CN1517711A/zh active Pending
- 2004-01-16 JP JP2004008803A patent/JP2004226402A/ja active Pending
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE102010044283A1 (de) * | 2010-09-03 | 2012-03-08 | M04 Tech Ug (Haftungsbeschränkt) | Vorrichtung und Verfahren zur Analyse biologischer Proben |
Also Published As
| Publication number | Publication date |
|---|---|
| EP1439472A1 (de) | 2004-07-21 |
| US20040158433A1 (en) | 2004-08-12 |
| CN102928541A (zh) | 2013-02-13 |
| EP1439472B1 (de) | 2017-03-15 |
| CN1517711A (zh) | 2004-08-04 |
| CN102928541B (zh) | 2019-09-13 |
| DK1439472T3 (en) | 2017-06-12 |
| JP2004226402A (ja) | 2004-08-12 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8127 | New person/name/address of the applicant |
Owner name: BAYER TECHNOLOGY SERVICES GMBH, 51373 LEVERKUSEN, |
|
| 8139 | Disposal/non-payment of the annual fee |