DE10238257B4 - Sorbicillacton A und Sorbicillacton-A-Derivate, Verfahren zu ihrer Herstellung und sie enthaltende Arzneimittel - Google Patents

Sorbicillacton A und Sorbicillacton-A-Derivate, Verfahren zu ihrer Herstellung und sie enthaltende Arzneimittel Download PDF

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Publication number
DE10238257B4
DE10238257B4 DE10238257A DE10238257A DE10238257B4 DE 10238257 B4 DE10238257 B4 DE 10238257B4 DE 10238257 A DE10238257 A DE 10238257A DE 10238257 A DE10238257 A DE 10238257A DE 10238257 B4 DE10238257 B4 DE 10238257B4
Authority
DE
Germany
Prior art keywords
alkyl
sorbicillactone
compound
branched
straight
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE10238257A
Other languages
German (de)
English (en)
Other versions
DE10238257A1 (de
Inventor
Gerhard Prof. Dr. Bringmann
Gerhard Lang
Jörg MÜHLBACHER
Karsten Dr. Schaumann
Stefan Steffens
Werner E.G. Prof. Dr. Müller
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
BAYERN FREISTAAT
Johannes Gutenberg-Universität Mainz
University of Würzburg
Original Assignee
BAYERN FREISTAAT
Johannes Gutenberg-Universität Mainz
University of Würzburg
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to DE10238257A priority Critical patent/DE10238257B4/de
Application filed by BAYERN FREISTAAT, Johannes Gutenberg-Universität Mainz, University of Würzburg filed Critical BAYERN FREISTAAT
Priority to AT03797201T priority patent/ATE346057T1/de
Priority to DE50305776T priority patent/DE50305776D1/de
Priority to CA002496386A priority patent/CA2496386A1/en
Priority to US10/525,685 priority patent/US20060111420A1/en
Priority to PCT/EP2003/007805 priority patent/WO2004026854A1/de
Priority to AU2003250985A priority patent/AU2003250985A1/en
Priority to JP2004536901A priority patent/JP2006503049A/ja
Priority to EP03797201A priority patent/EP1532129B1/de
Publication of DE10238257A1 publication Critical patent/DE10238257A1/de
Priority to ZA200502226A priority patent/ZA200502226B/en
Application granted granted Critical
Publication of DE10238257B4 publication Critical patent/DE10238257B4/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/86—Benzo [b] furans; Hydrogenated benzo [b] furans with an oxygen atom directly attached in position 7
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Rheumatology (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Molecular Biology (AREA)
  • Pain & Pain Management (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Furan Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DE10238257A 2002-08-21 2002-08-21 Sorbicillacton A und Sorbicillacton-A-Derivate, Verfahren zu ihrer Herstellung und sie enthaltende Arzneimittel Expired - Fee Related DE10238257B4 (de)

Priority Applications (10)

Application Number Priority Date Filing Date Title
DE10238257A DE10238257B4 (de) 2002-08-21 2002-08-21 Sorbicillacton A und Sorbicillacton-A-Derivate, Verfahren zu ihrer Herstellung und sie enthaltende Arzneimittel
EP03797201A EP1532129B1 (de) 2002-08-21 2003-07-17 Sorbicillacton-a-derivate zur behandlung von tumor- und viruserkrankungen
CA002496386A CA2496386A1 (en) 2002-08-21 2003-07-17 Sorbicillactone-a derivatives for the treatment of tumour and viral diseases
US10/525,685 US20060111420A1 (en) 2002-08-21 2003-07-17 Sorbicillactone-a derivatives for the treatment of tumour and viral diseases
PCT/EP2003/007805 WO2004026854A1 (de) 2002-08-21 2003-07-17 Sorbicillacton-a-derivate zur behandlung von tumor- und viruserkrankungen
AU2003250985A AU2003250985A1 (en) 2002-08-21 2003-07-17 Sorbicillactone-a derivatives for the treatment of tumour and viral diseases
AT03797201T ATE346057T1 (de) 2002-08-21 2003-07-17 Sorbicillacton-a-derivate zur behandlung von tumor- und viruserkrankungen
DE50305776T DE50305776D1 (de) 2002-08-21 2003-07-17 Sorbicillacton-a-derivate zur behandlung von tumor- und viruserkrankungen
JP2004536901A JP2006503049A (ja) 2002-08-21 2003-07-17 ソルビシルラクトンａおよびソルビシルラクトンａ誘導体、これらの製造方法、これらを含有する薬剤、およびこれらの使用
ZA200502226A ZA200502226B (en) 2002-08-21 2005-03-16 Sorbicillactone-A derivatives for the treatment oftumour and viral diseases.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE10238257A DE10238257B4 (de) 2002-08-21 2002-08-21 Sorbicillacton A und Sorbicillacton-A-Derivate, Verfahren zu ihrer Herstellung und sie enthaltende Arzneimittel

Publications (2)

Publication Number Publication Date
DE10238257A1 DE10238257A1 (de) 2004-03-11
DE10238257B4 true DE10238257B4 (de) 2007-04-19

Family

ID=31501834

Family Applications (2)

Application Number Title Priority Date Filing Date
DE10238257A Expired - Fee Related DE10238257B4 (de) 2002-08-21 2002-08-21 Sorbicillacton A und Sorbicillacton-A-Derivate, Verfahren zu ihrer Herstellung und sie enthaltende Arzneimittel
DE50305776T Expired - Fee Related DE50305776D1 (de) 2002-08-21 2003-07-17 Sorbicillacton-a-derivate zur behandlung von tumor- und viruserkrankungen

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE50305776T Expired - Fee Related DE50305776D1 (de) 2002-08-21 2003-07-17 Sorbicillacton-a-derivate zur behandlung von tumor- und viruserkrankungen

Country Status (9)

Country Link
US (1) US20060111420A1 (enExample)
EP (1) EP1532129B1 (enExample)
JP (1) JP2006503049A (enExample)
AT (1) ATE346057T1 (enExample)
AU (1) AU2003250985A1 (enExample)
CA (1) CA2496386A1 (enExample)
DE (2) DE10238257B4 (enExample)
WO (1) WO2004026854A1 (enExample)
ZA (1) ZA200502226B (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102004004901B4 (de) * 2004-01-30 2006-01-05 Johannes-Gutenberg-Universität Mainz Verfahren zur Herstellung von Sorbicillacton A
DE102004005106A1 (de) * 2004-02-02 2005-08-18 Johannes-Gutenberg-Universität Mainz Sorbifuranone, Sorbivineton, Sorbivinetol und Derivate dieser Verbindungen, Verfahren zu ihrer Herstellung, sie enthaltende Arzneimittel und deren Verwendung
KR102438137B1 (ko) 2015-12-02 2022-08-30 에스케이이노베이션 주식회사 내열성 및 셧다운 특성이 우수한 이차전지용 분리막
CN110037054B (zh) * 2019-04-16 2021-04-20 云南大学 一种提高烟草抗病性的水溶性多肽诱导剂及其应用
CN118496234A (zh) * 2024-05-09 2024-08-16 中国科学院南海海洋研究所 一种sorbicillin混杂二聚体类化合物sorbicillalanine A及其制备方法和在制备抗炎药物中的应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUP0100042A3 (en) * 1996-05-20 2003-01-28 Darwin Discovery Ltd Cambridge Benzofuran carboxamides medicaments containing the same and their therapeutic use
AU2001293048A1 (en) * 2000-09-26 2002-04-08 The Johns Hopkins University Antiviral compositions and methods of use

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Chem. Abstr. 134(2001), 311008 *

Also Published As

Publication number Publication date
DE50305776D1 (de) 2007-01-04
ATE346057T1 (de) 2006-12-15
AU2003250985A1 (en) 2004-04-08
EP1532129B1 (de) 2006-11-22
US20060111420A1 (en) 2006-05-25
DE10238257A1 (de) 2004-03-11
EP1532129A1 (de) 2005-05-25
ZA200502226B (en) 2006-02-22
WO2004026854A1 (de) 2004-04-01
JP2006503049A (ja) 2006-01-26
CA2496386A1 (en) 2004-04-01

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Legal Events

Date Code Title Description
OP8 Request for examination as to paragraph 44 patent law
8181 Inventor (new situation)

Inventor name: MUELLER, WERNER E.G., PROF. DR., 65203 WIESBADEN, D

Inventor name: MUEHLBACHER, JOERG, 79106 FREIBURG, DE

Inventor name: LANG, GERHARD, 97072 WUERZBURG, DE

Inventor name: BRINGMANN, GERHARD, PROF. DR., 97074 WUERZBURG, DE

Inventor name: STEFFENS, STEFAN, 52072 AACHEN, DE

Inventor name: SCHAUMANN, KARSTEN, DR., 27578 BREMERHAVEN, DE

8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee