AU2003250985A1 - Sorbicillactone-a derivatives for the treatment of tumour and viral diseases - Google Patents
Sorbicillactone-a derivatives for the treatment of tumour and viral diseases Download PDFInfo
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- AU2003250985A1 AU2003250985A1 AU2003250985A AU2003250985A AU2003250985A1 AU 2003250985 A1 AU2003250985 A1 AU 2003250985A1 AU 2003250985 A AU2003250985 A AU 2003250985A AU 2003250985 A AU2003250985 A AU 2003250985A AU 2003250985 A1 AU2003250985 A1 AU 2003250985A1
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- compound
- alkyl
- treatment
- sorbicillacton
- pharmaceutical composition
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- VMGAPWLDMVPYIA-HIDZBRGKSA-N n'-amino-n-iminomethanimidamide Chemical compound N\N=C\N=N VMGAPWLDMVPYIA-HIDZBRGKSA-N 0.000 description 1
- 230000004770 neurodegeneration Effects 0.000 description 1
- 208000015122 neurodegenerative disease Diseases 0.000 description 1
- 231100000989 no adverse effect Toxicity 0.000 description 1
- 239000006916 nutrient agar Substances 0.000 description 1
- 238000011275 oncology therapy Methods 0.000 description 1
- 229960001592 paclitaxel Drugs 0.000 description 1
- 239000002245 particle Substances 0.000 description 1
- 230000000144 pharmacologic effect Effects 0.000 description 1
- 239000004033 plastic Substances 0.000 description 1
- 230000003389 potentiating effect Effects 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 230000035755 proliferation Effects 0.000 description 1
- BDERNNFJNOPAEC-UHFFFAOYSA-N propan-1-ol Chemical compound CCCO BDERNNFJNOPAEC-UHFFFAOYSA-N 0.000 description 1
- 230000001681 protective effect Effects 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- BOLDJAUMGUJJKM-LSDHHAIUSA-N renifolin D Natural products CC(=C)[C@@H]1Cc2c(O)c(O)ccc2[C@H]1CC(=O)c3ccc(O)cc3O BOLDJAUMGUJJKM-LSDHHAIUSA-N 0.000 description 1
- 230000010076 replication Effects 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- SPWSUFUPTSJWNG-UHFFFAOYSA-N roquefortine C Natural products C=1C=CC=C2C=1NC1C2(C(C)(C=C)C)CC(C(N2)=O)N1C(=O)C2=CC1=CN=CN1 SPWSUFUPTSJWNG-UHFFFAOYSA-N 0.000 description 1
- 238000001896 rotating frame Overhauser effect spectroscopy Methods 0.000 description 1
- 239000007289 sea water agar Substances 0.000 description 1
- 230000035945 sensitivity Effects 0.000 description 1
- 239000000741 silica gel Substances 0.000 description 1
- 229910002027 silica gel Inorganic materials 0.000 description 1
- 238000004088 simulation Methods 0.000 description 1
- 238000000638 solvent extraction Methods 0.000 description 1
- 239000007858 starting material Substances 0.000 description 1
- 230000003068 static effect Effects 0.000 description 1
- 238000004659 sterilization and disinfection Methods 0.000 description 1
- 210000002784 stomach Anatomy 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- 239000005720 sucrose Substances 0.000 description 1
- 239000000725 suspension Substances 0.000 description 1
- 238000004114 suspension culture Methods 0.000 description 1
- 230000031068 symbiosis, encompassing mutualism through parasitism Effects 0.000 description 1
- 208000011580 syndromic disease Diseases 0.000 description 1
- RCINICONZNJXQF-MZXODVADSA-N taxol Chemical compound O([C@@H]1[C@@]2(C[C@@H](C(C)=C(C2(C)C)[C@H](C([C@]2(C)[C@@H](O)C[C@H]3OC[C@]3([C@H]21)OC(C)=O)=O)OC(=O)C)OC(=O)[C@H](O)[C@@H](NC(=O)C=1C=CC=CC=1)C=1C=CC=CC=1)O)C(=O)C1=CC=CC=C1 RCINICONZNJXQF-MZXODVADSA-N 0.000 description 1
- WMOVHXAZOJBABW-UHFFFAOYSA-N tert-butyl acetate Chemical compound CC(=O)OC(C)(C)C WMOVHXAZOJBABW-UHFFFAOYSA-N 0.000 description 1
- 125000003831 tetrazolyl group Chemical group 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 238000004809 thin layer chromatography Methods 0.000 description 1
- 231100000331 toxic Toxicity 0.000 description 1
- 230000002588 toxic effect Effects 0.000 description 1
- 238000013519 translation Methods 0.000 description 1
- 241001430294 unidentified retrovirus Species 0.000 description 1
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- 230000029812 viral genome replication Effects 0.000 description 1
- 239000003643 water by type Substances 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/86—Benzo [b] furans; Hydrogenated benzo [b] furans with an oxygen atom directly attached in position 7
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Virology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Pain & Pain Management (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Rheumatology (AREA)
- AIDS & HIV (AREA)
- Tropical Medicine & Parasitology (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Furan Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10238257.3 | 2002-08-21 | ||
| DE10238257A DE10238257B4 (de) | 2002-08-21 | 2002-08-21 | Sorbicillacton A und Sorbicillacton-A-Derivate, Verfahren zu ihrer Herstellung und sie enthaltende Arzneimittel |
| PCT/EP2003/007805 WO2004026854A1 (de) | 2002-08-21 | 2003-07-17 | Sorbicillacton-a-derivate zur behandlung von tumor- und viruserkrankungen |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AU2003250985A1 true AU2003250985A1 (en) | 2004-04-08 |
Family
ID=31501834
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2003250985A Abandoned AU2003250985A1 (en) | 2002-08-21 | 2003-07-17 | Sorbicillactone-a derivatives for the treatment of tumour and viral diseases |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US20060111420A1 (enExample) |
| EP (1) | EP1532129B1 (enExample) |
| JP (1) | JP2006503049A (enExample) |
| AT (1) | ATE346057T1 (enExample) |
| AU (1) | AU2003250985A1 (enExample) |
| CA (1) | CA2496386A1 (enExample) |
| DE (2) | DE10238257B4 (enExample) |
| WO (1) | WO2004026854A1 (enExample) |
| ZA (1) | ZA200502226B (enExample) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE102004004901B4 (de) * | 2004-01-30 | 2006-01-05 | Johannes-Gutenberg-Universität Mainz | Verfahren zur Herstellung von Sorbicillacton A |
| DE102004005106A1 (de) * | 2004-02-02 | 2005-08-18 | Johannes-Gutenberg-Universität Mainz | Sorbifuranone, Sorbivineton, Sorbivinetol und Derivate dieser Verbindungen, Verfahren zu ihrer Herstellung, sie enthaltende Arzneimittel und deren Verwendung |
| KR102438137B1 (ko) | 2015-12-02 | 2022-08-30 | 에스케이이노베이션 주식회사 | 내열성 및 셧다운 특성이 우수한 이차전지용 분리막 |
| CN110037054B (zh) * | 2019-04-16 | 2021-04-20 | 云南大学 | 一种提高烟草抗病性的水溶性多肽诱导剂及其应用 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HUP0100042A3 (en) * | 1996-05-20 | 2003-01-28 | Darwin Discovery Ltd Cambridge | Benzofuran carboxamides medicaments containing the same and their therapeutic use |
| AU2001293048A1 (en) * | 2000-09-26 | 2002-04-08 | The Johns Hopkins University | Antiviral compositions and methods of use |
-
2002
- 2002-08-21 DE DE10238257A patent/DE10238257B4/de not_active Expired - Fee Related
-
2003
- 2003-07-17 JP JP2004536901A patent/JP2006503049A/ja not_active Withdrawn
- 2003-07-17 WO PCT/EP2003/007805 patent/WO2004026854A1/de not_active Ceased
- 2003-07-17 CA CA002496386A patent/CA2496386A1/en not_active Abandoned
- 2003-07-17 AT AT03797201T patent/ATE346057T1/de not_active IP Right Cessation
- 2003-07-17 US US10/525,685 patent/US20060111420A1/en not_active Abandoned
- 2003-07-17 DE DE50305776T patent/DE50305776D1/de not_active Expired - Fee Related
- 2003-07-17 AU AU2003250985A patent/AU2003250985A1/en not_active Abandoned
- 2003-07-17 EP EP03797201A patent/EP1532129B1/de not_active Expired - Lifetime
-
2005
- 2005-03-16 ZA ZA200502226A patent/ZA200502226B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DE10238257B4 (de) | 2007-04-19 |
| JP2006503049A (ja) | 2006-01-26 |
| DE50305776D1 (de) | 2007-01-04 |
| ATE346057T1 (de) | 2006-12-15 |
| US20060111420A1 (en) | 2006-05-25 |
| EP1532129B1 (de) | 2006-11-22 |
| WO2004026854A1 (de) | 2004-04-01 |
| CA2496386A1 (en) | 2004-04-01 |
| EP1532129A1 (de) | 2005-05-25 |
| DE10238257A1 (de) | 2004-03-11 |
| ZA200502226B (en) | 2006-02-22 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MK1 | Application lapsed section 142(2)(a) - no request for examination in relevant period |