DE102008030046A1 - Kompaktiertes Polyallylamin-Polymer - Google Patents

Kompaktiertes Polyallylamin-Polymer Download PDF

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Publication number
DE102008030046A1
DE102008030046A1 DE102008030046A DE102008030046A DE102008030046A1 DE 102008030046 A1 DE102008030046 A1 DE 102008030046A1 DE 102008030046 A DE102008030046 A DE 102008030046A DE 102008030046 A DE102008030046 A DE 102008030046A DE 102008030046 A1 DE102008030046 A1 DE 102008030046A1
Authority
DE
Germany
Prior art keywords
tablets
polyallylamine polymer
pharmaceutically acceptable
polyallylamine
polymer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
DE102008030046A
Other languages
German (de)
English (en)
Inventor
Maria Dr. Genth
Max-Werner Dr. Scheiwe
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ratiopharm GmbH
Original Assignee
Ratiopharm GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ratiopharm GmbH filed Critical Ratiopharm GmbH
Priority to DE102008030046A priority Critical patent/DE102008030046A1/de
Priority to US13/001,242 priority patent/US20110189121A1/en
Priority to CA2731853A priority patent/CA2731853A1/en
Priority to EP09768863A priority patent/EP2309977A1/de
Priority to JP2011515137A priority patent/JP2011525501A/ja
Priority to PCT/EP2009/002071 priority patent/WO2009156014A1/de
Publication of DE102008030046A1 publication Critical patent/DE102008030046A1/de
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/785—Polymers containing nitrogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/009—Sachets, pouches characterised by the material or function of the envelope
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2009—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29B—PREPARATION OR PRETREATMENT OF THE MATERIAL TO BE SHAPED; MAKING GRANULES OR PREFORMS; RECOVERY OF PLASTICS OR OTHER CONSTITUENTS OF WASTE MATERIAL CONTAINING PLASTICS
    • B29B9/00—Making granules
    • B29B9/08—Making granules by agglomerating smaller particles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29B—PREPARATION OR PRETREATMENT OF THE MATERIAL TO BE SHAPED; MAKING GRANULES OR PREFORMS; RECOVERY OF PLASTICS OR OTHER CONSTITUENTS OF WASTE MATERIAL CONTAINING PLASTICS
    • B29B9/00—Making granules
    • B29B9/12—Making granules characterised by structure or composition

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Zoology (AREA)
  • Inorganic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Processes Of Treating Macromolecular Substances (AREA)
DE102008030046A 2008-06-25 2008-06-25 Kompaktiertes Polyallylamin-Polymer Withdrawn DE102008030046A1 (de)

Priority Applications (6)

Application Number Priority Date Filing Date Title
DE102008030046A DE102008030046A1 (de) 2008-06-25 2008-06-25 Kompaktiertes Polyallylamin-Polymer
US13/001,242 US20110189121A1 (en) 2008-06-25 2009-03-20 Bitablets comprising compacted polyallylamine polymer and method for the production thereof
CA2731853A CA2731853A1 (en) 2008-06-25 2009-03-20 Compacted polyallylamine polymer
EP09768863A EP2309977A1 (de) 2008-06-25 2009-03-20 Kompaktiertes polyallylamin-polymer enthaltende tabletten und verfahren zu deren herstellung
JP2011515137A JP2011525501A (ja) 2008-06-25 2009-03-20 緻密化ポリアリルアミンポリマー
PCT/EP2009/002071 WO2009156014A1 (de) 2008-06-25 2009-03-20 Kompaktiertes polyallylamin-polymer enthaltende tabletten und verfahren zu deren herstellung

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE102008030046A DE102008030046A1 (de) 2008-06-25 2008-06-25 Kompaktiertes Polyallylamin-Polymer

Publications (1)

Publication Number Publication Date
DE102008030046A1 true DE102008030046A1 (de) 2009-12-31

Family

ID=40600236

Family Applications (1)

Application Number Title Priority Date Filing Date
DE102008030046A Withdrawn DE102008030046A1 (de) 2008-06-25 2008-06-25 Kompaktiertes Polyallylamin-Polymer

Country Status (6)

Country Link
US (1) US20110189121A1 (https=)
EP (1) EP2309977A1 (https=)
JP (1) JP2011525501A (https=)
CA (1) CA2731853A1 (https=)
DE (1) DE102008030046A1 (https=)
WO (1) WO2009156014A1 (https=)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7964182B2 (en) 2006-09-01 2011-06-21 USV, Ltd Pharmaceutical compositions comprising phosphate-binding polymer
EP2389168A2 (en) * 2009-01-22 2011-11-30 USV Limited Pharmaceutical compositions comprising phosphate-binding polymer
EP2490675B1 (en) * 2009-10-22 2019-01-23 Synthon B.V. Pharmaceutical compositions of sevelamer
EP3003327B1 (en) 2013-06-05 2017-08-09 Tricida Inc. Proton-binding polymers for oral administration
EP2875807B1 (en) 2013-11-20 2021-03-24 Sanovel Ilac Sanayi ve Ticaret A.S. Tablet formulation of colesevelam
RS61409B1 (sr) 2014-12-10 2021-03-31 Tricida Inc Polimeri koji vezuju protone za oralnu primenu opis
US20180015119A1 (en) 2015-02-23 2018-01-18 Amneal Pharmaceuticals Company Gmbh Process for granulating sevelamer carbonate
US10245284B2 (en) 2015-08-19 2019-04-02 Alpex Pharma S.A. Granular composition for oral administration
CN109414453B (zh) 2016-05-06 2023-02-17 特里赛达公司 用于治疗酸碱失衡的组合物
CA3080651A1 (en) 2017-11-03 2019-05-09 Tricida, Inc. Compositions for and method of treating acid-base disorders
CN112972407A (zh) * 2019-12-18 2021-06-18 南京恒生制药有限公司 一种碳酸司维拉姆片剂组合物及其制备方法

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992013633A1 (de) * 1991-02-11 1992-08-20 Paul Gerteis Verfahren und vorrichtung zum kontinuierlichen mechanischen umformen von teilchenförmigen stoffen
EP0764174B1 (en) 1994-06-10 1999-09-01 Geltex Pharmaceuticals, Inc. Process for removing bile salts from a patient and alkylated compositions therefor
EP0716606B1 (en) 1993-08-11 2001-08-29 Geltex Pharmaceuticals, Inc. Phosphate-binding polymers for oral administration
EP1153940A1 (en) 1998-10-12 2001-11-14 Chugai Seiyaku Kabushiki Kaisha Polymer combining with phosphoric acid and preparation containing the same
EP1239837B1 (en) 1999-10-19 2005-01-05 Genzyme Corporation Direct compression polymer tablet core
WO2006050315A2 (en) 2004-11-01 2006-05-11 Genzyme Corporation Aliphatic amine polymer salts for tableting
EP1304104B1 (en) 1997-04-04 2007-06-13 Chugai Seiyaku Kabushiki Kaisha Tablet comprising a phosphate-binding polymer

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19758100B4 (de) * 1997-12-18 2006-05-04 Lichtwer Pharma Ag Verfahren zum Herstellen von Pflanzenextrakt enthaltenden pharmazeutischen Formulierungen
JP3363143B2 (ja) * 1998-10-12 2003-01-08 中外製薬株式会社 リン酸結合性ポリマー粒子
US20020054903A1 (en) * 1999-10-19 2002-05-09 Joseph Tyler Direct compression polymer tablet core
US7193006B2 (en) * 2002-12-06 2007-03-20 Nippon Shokubai Co., Ltd. Process for continuous production of water-absorbent resin product
CA2551528A1 (en) * 2003-12-31 2005-07-21 Genzyme Corporation Enteric coated aliphatic amine polymer bile acid sequestrants
ES2545589T3 (es) * 2005-04-08 2015-09-14 Abbott Laboratories Formulaciones farmacéuticas orales que comprenden sales de ácido fenofíbrico

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992013633A1 (de) * 1991-02-11 1992-08-20 Paul Gerteis Verfahren und vorrichtung zum kontinuierlichen mechanischen umformen von teilchenförmigen stoffen
EP0716606B1 (en) 1993-08-11 2001-08-29 Geltex Pharmaceuticals, Inc. Phosphate-binding polymers for oral administration
EP0764174B1 (en) 1994-06-10 1999-09-01 Geltex Pharmaceuticals, Inc. Process for removing bile salts from a patient and alkylated compositions therefor
EP1304104B1 (en) 1997-04-04 2007-06-13 Chugai Seiyaku Kabushiki Kaisha Tablet comprising a phosphate-binding polymer
EP1153940A1 (en) 1998-10-12 2001-11-14 Chugai Seiyaku Kabushiki Kaisha Polymer combining with phosphoric acid and preparation containing the same
EP1239837B1 (en) 1999-10-19 2005-01-05 Genzyme Corporation Direct compression polymer tablet core
WO2006050315A2 (en) 2004-11-01 2006-05-11 Genzyme Corporation Aliphatic amine polymer salts for tableting

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
BRUDY,Jörg: Systematische Rezepturentwicklung für die Walzenkompaktierung. Disseration,Universität,Heidelberg,publiziert am 01.08.2007. URL: http:// www.ub.uni-heidelberg.de/archiv/7484 $Kapitel 2$ *
BRUDY,Jörg: Systematische Rezepturentwicklung für die Walzenkompaktierung. Disseration,Universität,Heidelberg,publiziert am 01.08.2007. URL: http:// www.ub.uni-heidelberg.de/archiv/7484 Kapitel 2

Also Published As

Publication number Publication date
CA2731853A1 (en) 2009-12-30
US20110189121A1 (en) 2011-08-04
WO2009156014A8 (de) 2013-05-10
JP2011525501A (ja) 2011-09-22
EP2309977A1 (de) 2011-04-20
WO2009156014A1 (de) 2009-12-30

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OM8 Search report available as to paragraph 43 lit. 1 sentence 1 patent law
R119 Application deemed withdrawn, or ip right lapsed, due to non-payment of renewal fee

Effective date: 20140101