CA2731853A1 - Compacted polyallylamine polymer - Google Patents

Compacted polyallylamine polymer Download PDF

Info

Publication number
CA2731853A1
CA2731853A1 CA2731853A CA2731853A CA2731853A1 CA 2731853 A1 CA2731853 A1 CA 2731853A1 CA 2731853 A CA2731853 A CA 2731853A CA 2731853 A CA2731853 A CA 2731853A CA 2731853 A1 CA2731853 A1 CA 2731853A1
Authority
CA
Canada
Prior art keywords
polyallylamine polymer
tablets
compaction
sevelamer
slug
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA2731853A
Other languages
English (en)
French (fr)
Inventor
Maria Genth
Max-Werner Scheiwe
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ratiopharm GmbH
Original Assignee
Ratiopharm GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ratiopharm GmbH filed Critical Ratiopharm GmbH
Publication of CA2731853A1 publication Critical patent/CA2731853A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/785—Polymers containing nitrogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/009—Sachets, pouches characterised by the material or function of the envelope
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2009—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29B—PREPARATION OR PRETREATMENT OF THE MATERIAL TO BE SHAPED; MAKING GRANULES OR PREFORMS; RECOVERY OF PLASTICS OR OTHER CONSTITUENTS OF WASTE MATERIAL CONTAINING PLASTICS
    • B29B9/00—Making granules
    • B29B9/08—Making granules by agglomerating smaller particles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29B—PREPARATION OR PRETREATMENT OF THE MATERIAL TO BE SHAPED; MAKING GRANULES OR PREFORMS; RECOVERY OF PLASTICS OR OTHER CONSTITUENTS OF WASTE MATERIAL CONTAINING PLASTICS
    • B29B9/00—Making granules
    • B29B9/12—Making granules characterised by structure or composition

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Inorganic Chemistry (AREA)
  • Mechanical Engineering (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Urology & Nephrology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Processes Of Treating Macromolecular Substances (AREA)
CA2731853A 2008-06-25 2009-03-20 Compacted polyallylamine polymer Abandoned CA2731853A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE102008030046.2 2008-06-25
DE102008030046A DE102008030046A1 (de) 2008-06-25 2008-06-25 Kompaktiertes Polyallylamin-Polymer
PCT/EP2009/002071 WO2009156014A1 (de) 2008-06-25 2009-03-20 Kompaktiertes polyallylamin-polymer enthaltende tabletten und verfahren zu deren herstellung

Publications (1)

Publication Number Publication Date
CA2731853A1 true CA2731853A1 (en) 2009-12-30

Family

ID=40600236

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2731853A Abandoned CA2731853A1 (en) 2008-06-25 2009-03-20 Compacted polyallylamine polymer

Country Status (6)

Country Link
US (1) US20110189121A1 (https=)
EP (1) EP2309977A1 (https=)
JP (1) JP2011525501A (https=)
CA (1) CA2731853A1 (https=)
DE (1) DE102008030046A1 (https=)
WO (1) WO2009156014A1 (https=)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7964182B2 (en) 2006-09-01 2011-06-21 USV, Ltd Pharmaceutical compositions comprising phosphate-binding polymer
US20110081413A1 (en) * 2009-01-22 2011-04-07 Ashok Omray Pharmaceutical Compositions Comprising Phosphate-Binding Polymer
ES2720869T3 (es) * 2009-10-22 2019-07-25 Synthon Bv Composiciones farmacéuticas de sevelámero
SI3287133T1 (sl) 2013-06-05 2019-09-30 Tricida Inc. Polimeri, ki vežejo protone,za peroralno dajanje
EP2875807B1 (en) 2013-11-20 2021-03-24 Sanovel Ilac Sanayi ve Ticaret A.S. Tablet formulation of colesevelam
LT3229816T (lt) 2014-12-10 2020-05-25 Tricida Inc. Protoną prijungiantys polimerai, skirti peroraliniam įvedimui
EP3261624A1 (en) 2015-02-23 2018-01-03 Amneal Pharmaceuticals Company GmbH Process for granulating sevelamer carbonate
US10245284B2 (en) * 2015-08-19 2019-04-02 Alpex Pharma S.A. Granular composition for oral administration
WO2017193024A1 (en) 2016-05-06 2017-11-09 Tricida, Inc. Hcl-binding compositions for and method of treating acid-base disorders
IL319146A (en) 2017-11-03 2025-04-01 Tricida Inc Compositions for and method of treating acid-base disorders
CN112972407A (zh) * 2019-12-18 2021-06-18 南京恒生制药有限公司 一种碳酸司维拉姆片剂组合物及其制备方法

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0525135B1 (de) * 1991-02-11 1995-06-28 GERTEIS, Paul VORRICHTUNG ZUM KONTINUIERLICHEN MECHANISCHEN UMFORMEN VON TEILCHENFöRMIGEN STOFFEN.
US5496545A (en) 1993-08-11 1996-03-05 Geltex Pharmaceuticals, Inc. Phosphate-binding polymers for oral administration
TW474813B (en) 1994-06-10 2002-02-01 Geltex Pharma Inc Alkylated composition for removing bile salts from a patient
TW592727B (en) 1997-04-04 2004-06-21 Chugai Pharmaceutical Co Ltd Phosphate-binding polymer preparations
DE19758100B4 (de) * 1997-12-18 2006-05-04 Lichtwer Pharma Ag Verfahren zum Herstellen von Pflanzenextrakt enthaltenden pharmazeutischen Formulierungen
TW568788B (en) 1998-10-12 2004-01-01 Chugai Pharmaceutical Co Ltd Polymer combining with phosphoric acid and preparation containing the same
JP3363143B2 (ja) * 1998-10-12 2003-01-08 中外製薬株式会社 リン酸結合性ポリマー粒子
US20020054903A1 (en) * 1999-10-19 2002-05-09 Joseph Tyler Direct compression polymer tablet core
KR100794427B1 (ko) 1999-10-19 2008-01-16 젠자임 코포레이션 직접 압축형 중합체 정제 코어
US7193006B2 (en) * 2002-12-06 2007-03-20 Nippon Shokubai Co., Ltd. Process for continuous production of water-absorbent resin product
WO2005065291A2 (en) * 2003-12-31 2005-07-21 Genzyme Corporation Enteric coated aliphatic amine polymer bile acid sequestrants
US7985418B2 (en) 2004-11-01 2011-07-26 Genzyme Corporation Aliphatic amine polymer salts for tableting
CN101217944A (zh) * 2005-04-08 2008-07-09 艾博特公司 包含非诺贝酸和/或其盐的口服药物制剂

Also Published As

Publication number Publication date
WO2009156014A1 (de) 2009-12-30
DE102008030046A1 (de) 2009-12-31
WO2009156014A8 (de) 2013-05-10
US20110189121A1 (en) 2011-08-04
EP2309977A1 (de) 2011-04-20
JP2011525501A (ja) 2011-09-22

Similar Documents

Publication Publication Date Title
US20110189121A1 (en) Bitablets comprising compacted polyallylamine polymer and method for the production thereof
ES2467105T3 (es) Moxifloxacino compactado
ES2639130T3 (es) Formulación farmacéutica para la fabricación de comprimidos de rápida desintegración
US9579343B2 (en) Direct compression polymer tablet core
WO2004032906A1 (en) Gastro-retentive levodopa delivery form
US20120009258A1 (en) Compacted cinacalcet
MX2012002789A (es) Tableta antiacida y laxante.
WO2013026553A1 (en) Composition comprising edoxaban
WO2009022169A1 (en) Solid valsartan composition
EP2680823B1 (en) Binder powders
CA2785684A1 (en) Melt-granulated cinacalcet
EP2745848B1 (en) Orally disintegrating tablet containing hydroxyalkyl cellulose fine particles
CN113490491A (zh) 固体微粉化褪黑激素组合物
WO2015136329A1 (en) Pharmaceutical composition of cinacalcet
JP2023143873A (ja) ミラベグロン含有徐放性錠剤及びその製造方法、並びにミラベグロン含有徐放性錠剤の変色・膨張抑制方法
EP2197424A2 (en) Improved pharmaceutical composition containing antiviral agent and method for the preparation thereof
WO2014184380A1 (en) Tablet with increased drug load of odanacatib
EP2696857A1 (en) Pharmaceutical composition comprising bosentan
JP7607621B2 (ja) 錠剤の製造方法及び造粒粒子群
EP3875077B1 (en) Dosage form providing prolonged release of tapentadol phosphoric acid salt
US20240350414A1 (en) Direct tableting auxiliary composition
EP1541133B1 (en) Pharmaceutical formulation of valaciclovir
NZ530973A (en) Pharmaceutical formulation containing an LTB4 antagonist
WO2018087097A1 (en) Extended release tablet comprising a weight-loss drug
JP2025161786A (ja) レテルモビル含有医薬組成物ならびにその製造方法および用途

Legal Events

Date Code Title Description
FZDE Discontinued

Effective date: 20150320