DE102008008256A1 - Mikroreaktor - Google Patents

Mikroreaktor Download PDF

Info

Publication number
DE102008008256A1
DE102008008256A1 DE102008008256A DE102008008256A DE102008008256A1 DE 102008008256 A1 DE102008008256 A1 DE 102008008256A1 DE 102008008256 A DE102008008256 A DE 102008008256A DE 102008008256 A DE102008008256 A DE 102008008256A DE 102008008256 A1 DE102008008256 A1 DE 102008008256A1
Authority
DE
Germany
Prior art keywords
lid
microreactor
microreactor according
wall
cavity
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
DE102008008256A
Other languages
German (de)
English (en)
Inventor
Frank Kensy
Carsten Müller
Jochen Büchs
Matthias Funke
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
M2p Labs GmbH
Original Assignee
M2p Labs GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by M2p Labs GmbH filed Critical M2p Labs GmbH
Priority to DE102008008256A priority Critical patent/DE102008008256A1/de
Priority to EP08837177.8A priority patent/EP2205716B1/de
Priority to DE112008002590.8T priority patent/DE112008002590B4/de
Priority to US12/734,054 priority patent/US8828337B2/en
Priority to DK08837177.8T priority patent/DK2205716T3/en
Priority to CN2008801192016A priority patent/CN101932693B/zh
Priority to JP2010527321A priority patent/JP2011501689A/ja
Priority to PCT/DE2008/001623 priority patent/WO2009046697A2/de
Publication of DE102008008256A1 publication Critical patent/DE102008008256A1/de
Withdrawn legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00Constructional details, e.g. recesses, hinges
    • C12M23/38Caps; Covers; Plugs; Pouring means
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F31/00Mixers with shaking, oscillating, or vibrating mechanisms
    • B01F31/20Mixing the contents of independent containers, e.g. test tubes
    • B01F31/22Mixing the contents of independent containers, e.g. test tubes with supporting means moving in a horizontal plane, e.g. describing an orbital path for moving the containers about an axis which intersects the receptacle axis at an angle
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/50Mixing receptacles
    • B01F35/53Mixing receptacles characterised by the configuration of the interior, e.g. baffles for facilitating the mixing of components
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/508Rigid containers without fluid transport within
    • B01L3/5085Rigid containers without fluid transport within for multiple samples, e.g. microtitration plates
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00Constructional details, e.g. recesses, hinges
    • C12M23/02Form or structure of the vessel
    • C12M23/12Well or multiwell plates
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00Constructional details, e.g. recesses, hinges
    • C12M23/24Gas permeable parts
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277Apparatus
    • B01J2219/00279Features relating to reactor vessels
    • B01J2219/00306Reactor vessels in a multiple arrangement
    • B01J2219/00313Reactor vessels in a multiple arrangement the reactor vessels being formed by arrays of wells in blocks
    • B01J2219/00315Microtiter plates
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277Apparatus
    • B01J2219/00479Means for mixing reactants or products in the reaction vessels
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/08Geometry, shape and general structure
    • B01L2300/0809Geometry, shape and general structure rectangular shaped
    • B01L2300/0829Multi-well plates; Microtitration plates
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/08Geometry, shape and general structure
    • B01L2300/0848Specific forms of parts of containers
    • B01L2300/0858Side walls

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Clinical Laboratory Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Sustainable Development (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Analytical Chemistry (AREA)
  • Hematology (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Micromachines (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
DE102008008256A 2007-10-08 2008-02-08 Mikroreaktor Withdrawn DE102008008256A1 (de)

Priority Applications (8)

Application Number Priority Date Filing Date Title
DE102008008256A DE102008008256A1 (de) 2007-10-08 2008-02-08 Mikroreaktor
EP08837177.8A EP2205716B1 (de) 2007-10-08 2008-10-08 Mikroreaktor
DE112008002590.8T DE112008002590B4 (de) 2007-10-08 2008-10-08 Mikroreaktor
US12/734,054 US8828337B2 (en) 2007-10-08 2008-10-08 Microreactor
DK08837177.8T DK2205716T3 (en) 2007-10-08 2008-10-08 MICRO REACTOR
CN2008801192016A CN101932693B (zh) 2007-10-08 2008-10-08 微型反应器
JP2010527321A JP2011501689A (ja) 2007-10-08 2008-10-08 マイクロリアクタ
PCT/DE2008/001623 WO2009046697A2 (de) 2007-10-08 2008-10-08 Mikroreaktor

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE102007048201 2007-10-08
DE102007048201.0 2007-10-08
DE102008008256A DE102008008256A1 (de) 2007-10-08 2008-02-08 Mikroreaktor

Publications (1)

Publication Number Publication Date
DE102008008256A1 true DE102008008256A1 (de) 2009-04-09

Family

ID=40418270

Family Applications (2)

Application Number Title Priority Date Filing Date
DE102008008256A Withdrawn DE102008008256A1 (de) 2007-10-08 2008-02-08 Mikroreaktor
DE112008002590.8T Active DE112008002590B4 (de) 2007-10-08 2008-10-08 Mikroreaktor

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE112008002590.8T Active DE112008002590B4 (de) 2007-10-08 2008-10-08 Mikroreaktor

Country Status (7)

Country Link
US (1) US8828337B2 (https=)
EP (1) EP2205716B1 (https=)
JP (1) JP2011501689A (https=)
CN (1) CN101932693B (https=)
DE (2) DE102008008256A1 (https=)
DK (1) DK2205716T3 (https=)
WO (1) WO2009046697A2 (https=)

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011026559A1 (en) * 2009-09-05 2011-03-10 Lonza Biologics Plc Deepwell plate system with lid
US20120122729A1 (en) * 2009-07-30 2012-05-17 Muesken Mathias Methods and Tests for Screening Bacterial Biofilms
WO2013153187A3 (en) * 2012-04-11 2013-12-05 Stat-Diagnostica & Innovation, S.L. Fluidically integrated magnetic bead beater
DE102016116377A1 (de) * 2016-09-01 2018-03-01 Rheinisch-Westfälisch Technische Hochschule (RWTH) Aachen Verfahren und Vorrichtung zur Erfassung von Prozessparametern in Flüssigkulturen
WO2018136752A3 (en) * 2017-01-19 2018-09-13 Essen Instruments, Inc. D.B.A. Essen Bioscience, Inc. Methods and apparatus for perfusion and environment control of microplate labware
WO2019014541A3 (en) * 2017-07-13 2019-03-07 Greiner Bio-One North America, Inc. CULTURE PLATES FOR IMAGING
DE102018112895A1 (de) 2018-05-30 2019-12-05 Presens Precision Sensing Gmbh Behältnis, Vorrichtung und Verfahren zur Erfassung mindestens einer Veränderlichen während eines biologisch / chemischen Prozesses
WO2024188448A1 (de) * 2023-03-13 2024-09-19 Hombrechtikon Systems Engineering Ag Behälter, mischungsvorrichtung und verfahren zur verwendung einer mischungsvorrichtung

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102009057223B4 (de) * 2009-12-05 2016-03-24 Chemagen Biopolymer-Technologie Aktiengesellschaft Probengefäßmatrix und deren Herstellungsverfahren
GB201103665D0 (en) * 2011-03-04 2011-04-13 Univ Cardiff Correlative microscopy
JP5981653B2 (ja) * 2012-08-06 2016-08-31 カウンシル オブ サイエンティフィック アンド インダストリアル リサーチ 無菌条件下の植物の大規模成長のためのバイオリアクタ容器
US9550972B2 (en) 2014-09-29 2017-01-24 General Electric Company Devices, systems and methods for automated cell culturing
US11975330B2 (en) * 2017-01-31 2024-05-07 Myriad Women's Health, Inc. Devices for handling laboratory plates and methods of using the same
GB201709140D0 (en) * 2017-06-08 2017-07-26 Vitrolife As Lid for culture dish
US12390785B2 (en) 2019-11-28 2025-08-19 Council Of Scientific And Industrial Research Continuous flow reactor
CN110907420B (zh) * 2019-12-04 2021-07-02 中国科学院过程工程研究所 一种不互溶液-液相间传质平衡时间的测量装置及利用其的测量方法
EP3910051A1 (en) 2020-05-13 2021-11-17 Evonik Operations GmbH Bioreactors for orbitally shaking cell cultures, in particular suspension cultures
JP7849953B2 (ja) * 2020-10-19 2026-04-22 Agcテクノグラス株式会社 培養容器
US12011712B2 (en) * 2020-11-10 2024-06-18 National Health Research Institutes High-efficiency single-cell collection method
KR20240005042A (ko) 2021-05-07 2024-01-11 베크만 컬터, 인코포레이티드 미생물반응기용 용기 조립체
CA3218177A1 (en) 2021-05-07 2022-11-10 Beckman Coulter, Inc. Container assembly for microbioreactor
WO2022235597A1 (en) 2021-05-07 2022-11-10 Beckman Coulter, Inc. Control of ph in parallel culture wells
WO2025136489A1 (en) 2023-12-19 2025-06-26 Beckman Coulter, Inc. Automated system for clone selection based on antibody production and measurement of cell health parameters

Citations (15)

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Publication number Priority date Publication date Assignee Title
US5225164A (en) * 1991-09-30 1993-07-06 Astle Thomas W Microplate laboratory tray with rectilinear wells
DE10159091A1 (de) * 2001-12-01 2003-06-12 Evotec Ag Trägersysteme und Verfahren zu ihrer Herstellung
DE20121739U1 (de) * 2001-10-08 2003-08-28 Mecadi GmbH-Chemicals/Processing, 66424 Homburg Platte für parallelisierte Analysen und Synthesen
DE69913978T2 (de) * 1998-10-29 2004-12-23 Applera Corp., Foster City Multiprobenbehältermikrofiltrationsvorrichtung
EP1508373A2 (de) * 2003-08-19 2005-02-23 Herbener, Heinz-Gerd Probenträger mit Flüssigkeitskanal
DE10117275B4 (de) * 2001-04-06 2005-02-24 Hte Ag The High Throughput Experimentation Company Vorrichtung zur Archivierung und Analyse von Materialien
US6896848B1 (en) 2000-12-19 2005-05-24 Tekcel, Inc. Microplate cover assembly
WO2005098397A1 (de) 2004-04-02 2005-10-20 Rwth Aachen Verfahren und vorrichtung zur erfassung von prozessparametern von reaktionsflüssigkeiten in mehreren geschüttelten mikroreaktoren
DE69733366T2 (de) * 1997-04-09 2006-01-26 Minnesota Mining And Mfg. Co., St. Paul Verfahren und vorrichtungen zur unterteilung biologischer probenflüssigkeiten in mikroflüssigkeitsmengen
DE202006004642U1 (de) * 2005-03-29 2006-06-08 Sartorius Ag Mikroarray-Vorrichtung zum Präparieren eines Probenträgers
DE60215377T2 (de) * 2001-06-14 2007-08-23 Millipore Corp., Billerica Multiwell-Zellwachstumsvorrichtung
DE60309962T2 (de) * 2002-05-23 2007-09-20 Millipore Corp., Billerica Einteilige Filterplatte
AT500167B1 (de) * 2001-06-18 2007-10-15 Greiner Bio One Gmbh Reaktionsgefäss
DE112006000361T5 (de) * 2005-02-18 2007-12-27 National University Corporation Saitama University Verfahren zur Einführung und Überführung einer Vielzahl kleinster Probenmengen
EP1944080A1 (de) * 2007-01-11 2008-07-16 F.Hoffmann-La Roche Ag Vorrichtung und Verfahren zum Bewegen einer Flüssigkeit in einer Kavität

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USD403077S (en) 1997-05-12 1998-12-22 Neogen Corporation Microorganism culture tray
US6890488B2 (en) * 2001-06-22 2005-05-10 Matrix Technologies, Inc. Apparatus for sealing test tubes and the like
US8257967B2 (en) * 2002-04-26 2012-09-04 Board Of Regents, The University Of Texas System Method and system for the detection of cardiac risk factors
JP2003344433A (ja) 2002-05-22 2003-12-03 Okutekku:Kk マイクロアレイ、マイクロアレイシステム及び被検物質の測定方法
US20060286003A1 (en) 2005-06-16 2006-12-21 Desilets Kenneth G Multi-well filter plate with shifted wells and U-bottom receiver plate
US20100203621A1 (en) 2007-07-25 2010-08-12 Panasonic Corporation Biosensor

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Publication number Priority date Publication date Assignee Title
US5225164A (en) * 1991-09-30 1993-07-06 Astle Thomas W Microplate laboratory tray with rectilinear wells
DE69733366T2 (de) * 1997-04-09 2006-01-26 Minnesota Mining And Mfg. Co., St. Paul Verfahren und vorrichtungen zur unterteilung biologischer probenflüssigkeiten in mikroflüssigkeitsmengen
DE69913978T2 (de) * 1998-10-29 2004-12-23 Applera Corp., Foster City Multiprobenbehältermikrofiltrationsvorrichtung
US6896848B1 (en) 2000-12-19 2005-05-24 Tekcel, Inc. Microplate cover assembly
DE10117275B4 (de) * 2001-04-06 2005-02-24 Hte Ag The High Throughput Experimentation Company Vorrichtung zur Archivierung und Analyse von Materialien
DE60215377T2 (de) * 2001-06-14 2007-08-23 Millipore Corp., Billerica Multiwell-Zellwachstumsvorrichtung
AT500167B1 (de) * 2001-06-18 2007-10-15 Greiner Bio One Gmbh Reaktionsgefäss
DE20121739U1 (de) * 2001-10-08 2003-08-28 Mecadi GmbH-Chemicals/Processing, 66424 Homburg Platte für parallelisierte Analysen und Synthesen
DE10159091A1 (de) * 2001-12-01 2003-06-12 Evotec Ag Trägersysteme und Verfahren zu ihrer Herstellung
DE60309962T2 (de) * 2002-05-23 2007-09-20 Millipore Corp., Billerica Einteilige Filterplatte
EP1508373A2 (de) * 2003-08-19 2005-02-23 Herbener, Heinz-Gerd Probenträger mit Flüssigkeitskanal
WO2005098397A1 (de) 2004-04-02 2005-10-20 Rwth Aachen Verfahren und vorrichtung zur erfassung von prozessparametern von reaktionsflüssigkeiten in mehreren geschüttelten mikroreaktoren
DE112006000361T5 (de) * 2005-02-18 2007-12-27 National University Corporation Saitama University Verfahren zur Einführung und Überführung einer Vielzahl kleinster Probenmengen
DE202006004642U1 (de) * 2005-03-29 2006-06-08 Sartorius Ag Mikroarray-Vorrichtung zum Präparieren eines Probenträgers
EP1944080A1 (de) * 2007-01-11 2008-07-16 F.Hoffmann-La Roche Ag Vorrichtung und Verfahren zum Bewegen einer Flüssigkeit in einer Kavität

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Buchs J., Introduction to advantages and Problems of shaken cultures, Biochem. Eng. J. 7(2), 91-98, 2001
Hermann R., Lehmann M., Büchs J.: Characterization of gas-liquid mass transfer phenomena in microtiter plates. Biotechnol Bioeng, 81(2), 178-186, 2003
Kensy F., John G. T., Hofmann B., Büchs J., Characterisation of Operation conditions and online monitoring of physiological culture parameters in shaken 24-well microtiter plates; Bioprocess and Biosystems Engineering 28(2), 75-81, 2005

Cited By (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10179928B2 (en) * 2009-07-30 2019-01-15 Helmholtz-Zentrum Fuer Infektionsforschung Gmbh Methods and tests for screening bacterial biofilms
US20120122729A1 (en) * 2009-07-30 2012-05-17 Muesken Mathias Methods and Tests for Screening Bacterial Biofilms
CN102481572A (zh) * 2009-09-05 2012-05-30 英国龙沙生物医药股份有限公司 有罩的深孔板系统
JP2013504041A (ja) * 2009-09-05 2013-02-04 ロンザ バイオロジクス ピーエルシー 蓋付きディープウェルプレートシステム
CN104789470A (zh) * 2009-09-05 2015-07-22 英国龙沙生物医药股份有限公司 有罩的深孔板系统
US9783770B2 (en) 2009-09-05 2017-10-10 Lonza Biologics Plc Deepwell plate system with lid
WO2011026559A1 (en) * 2009-09-05 2011-03-10 Lonza Biologics Plc Deepwell plate system with lid
WO2013153187A3 (en) * 2012-04-11 2013-12-05 Stat-Diagnostica & Innovation, S.L. Fluidically integrated magnetic bead beater
US9333471B2 (en) 2012-04-11 2016-05-10 STAT—Diagnostica & Innovation, S.L. Fluidically integrated magnetic bead beater
DE102016116377A1 (de) * 2016-09-01 2018-03-01 Rheinisch-Westfälisch Technische Hochschule (RWTH) Aachen Verfahren und Vorrichtung zur Erfassung von Prozessparametern in Flüssigkulturen
US11635381B2 (en) 2016-09-01 2023-04-25 Rheinisch-Westfälisch Technische Hochschule (RWTH) Aachen Method and device for measuring process parameters in liquid cultures
WO2018136752A3 (en) * 2017-01-19 2018-09-13 Essen Instruments, Inc. D.B.A. Essen Bioscience, Inc. Methods and apparatus for perfusion and environment control of microplate labware
US10633624B2 (en) 2017-01-19 2020-04-28 Essen Instruments, Inc. Methods and apparatus for perfusion and environment control of microplate labware
US11149242B2 (en) 2017-01-19 2021-10-19 Essen Instruments, Inc. Methods and apparatus for perfusion and environment control of microplate lab ware
WO2019014541A3 (en) * 2017-07-13 2019-03-07 Greiner Bio-One North America, Inc. CULTURE PLATES FOR IMAGING
US12049612B2 (en) 2017-07-13 2024-07-30 Greiner Bio-One North America, Inc. Culture plates for imaging
DE102018112895A1 (de) 2018-05-30 2019-12-05 Presens Precision Sensing Gmbh Behältnis, Vorrichtung und Verfahren zur Erfassung mindestens einer Veränderlichen während eines biologisch / chemischen Prozesses
DE102018112895B4 (de) 2018-05-30 2024-05-08 Presens Precision Sensing Gmbh System, Vorrichtung und Verfahren zur Erfassung mindestens einer Veränderlichen während eines biologisch / chemischen Prozesses
WO2024188448A1 (de) * 2023-03-13 2024-09-19 Hombrechtikon Systems Engineering Ag Behälter, mischungsvorrichtung und verfahren zur verwendung einer mischungsvorrichtung

Also Published As

Publication number Publication date
US20100248995A1 (en) 2010-09-30
EP2205716A2 (de) 2010-07-14
DK2205716T3 (en) 2017-12-04
DE112008002590B4 (de) 2022-02-24
US8828337B2 (en) 2014-09-09
WO2009046697A3 (de) 2009-09-11
EP2205716B1 (de) 2017-09-27
WO2009046697A9 (de) 2009-07-23
DE112008002590A5 (de) 2010-06-24
WO2009046697A2 (de) 2009-04-16
JP2011501689A (ja) 2011-01-13
CN101932693A (zh) 2010-12-29
CN101932693B (zh) 2013-03-27

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