DE102006018293A1 - Pädiatrische Aminosäurelösung zur parenteralen Ernäherung - Google Patents
Pädiatrische Aminosäurelösung zur parenteralen Ernäherung Download PDFInfo
- Publication number
- DE102006018293A1 DE102006018293A1 DE102006018293A DE102006018293A DE102006018293A1 DE 102006018293 A1 DE102006018293 A1 DE 102006018293A1 DE 102006018293 A DE102006018293 A DE 102006018293A DE 102006018293 A DE102006018293 A DE 102006018293A DE 102006018293 A1 DE102006018293 A1 DE 102006018293A1
- Authority
- DE
- Germany
- Prior art keywords
- amino acid
- acid solution
- amino acids
- glutamine
- tyrosine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
- 150000001413 amino acids Chemical class 0.000 title claims abstract description 120
- 235000016236 parenteral nutrition Nutrition 0.000 title claims abstract description 28
- 235000001014 amino acid Nutrition 0.000 claims abstract description 105
- ZDXPYRJPNDTMRX-UHFFFAOYSA-N glutamine Natural products OC(=O)C(N)CCC(N)=O ZDXPYRJPNDTMRX-UHFFFAOYSA-N 0.000 claims abstract description 31
- XOAAWQZATWQOTB-UHFFFAOYSA-N taurine Chemical compound NCCS(O)(=O)=O XOAAWQZATWQOTB-UHFFFAOYSA-N 0.000 claims abstract description 28
- OUYCCCASQSFEME-QMMMGPOBSA-N L-tyrosine Chemical compound OC(=O)[C@@H](N)CC1=CC=C(O)C=C1 OUYCCCASQSFEME-QMMMGPOBSA-N 0.000 claims abstract description 27
- OUYCCCASQSFEME-UHFFFAOYSA-N tyrosine Natural products OC(=O)C(N)CC1=CC=C(O)C=C1 OUYCCCASQSFEME-UHFFFAOYSA-N 0.000 claims abstract description 27
- 235000018417 cysteine Nutrition 0.000 claims abstract description 17
- XUJNEKJLAYXESH-UHFFFAOYSA-N cysteine Natural products SCC(N)C(O)=O XUJNEKJLAYXESH-UHFFFAOYSA-N 0.000 claims abstract description 17
- COLNVLDHVKWLRT-QMMMGPOBSA-N L-phenylalanine Chemical compound OC(=O)[C@@H](N)CC1=CC=CC=C1 COLNVLDHVKWLRT-QMMMGPOBSA-N 0.000 claims abstract description 14
- 108010038807 Oligopeptides Proteins 0.000 claims abstract description 14
- 102000015636 Oligopeptides Human genes 0.000 claims abstract description 14
- COLNVLDHVKWLRT-UHFFFAOYSA-N phenylalanine Natural products OC(=O)C(N)CC1=CC=CC=C1 COLNVLDHVKWLRT-UHFFFAOYSA-N 0.000 claims abstract description 14
- 229960003080 taurine Drugs 0.000 claims abstract description 14
- FFEARJCKVFRZRR-BYPYZUCNSA-N L-methionine Chemical compound CSCC[C@H](N)C(O)=O FFEARJCKVFRZRR-BYPYZUCNSA-N 0.000 claims abstract description 9
- 229930182817 methionine Natural products 0.000 claims abstract description 9
- XUJNEKJLAYXESH-REOHCLBHSA-N L-Cysteine Chemical compound SC[C@H](N)C(O)=O XUJNEKJLAYXESH-REOHCLBHSA-N 0.000 claims abstract description 8
- 229940024606 amino acid Drugs 0.000 claims description 103
- 239000000243 solution Substances 0.000 claims description 52
- 239000000203 mixture Substances 0.000 claims description 19
- 230000001954 sterilising effect Effects 0.000 claims description 18
- 238000004659 sterilization and disinfection Methods 0.000 claims description 18
- 235000018102 proteins Nutrition 0.000 claims description 15
- 108090000623 proteins and genes Proteins 0.000 claims description 15
- 102000004169 proteins and genes Human genes 0.000 claims description 15
- 230000037396 body weight Effects 0.000 claims description 11
- HJCMDXDYPOUFDY-WHFBIAKZSA-N Ala-Gln Chemical compound C[C@H](N)C(=O)N[C@H](C(O)=O)CCC(N)=O HJCMDXDYPOUFDY-WHFBIAKZSA-N 0.000 claims description 5
- 229960002648 alanylglutamine Drugs 0.000 claims description 5
- 238000002360 preparation method Methods 0.000 claims description 5
- WHUUTDBJXJRKMK-VKHMYHEASA-N L-glutamic acid Chemical compound OC(=O)[C@@H](N)CCC(O)=O WHUUTDBJXJRKMK-VKHMYHEASA-N 0.000 claims description 4
- 150000001720 carbohydrates Chemical class 0.000 claims description 3
- 235000014633 carbohydrates Nutrition 0.000 claims description 3
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- 239000003925 fat Substances 0.000 claims description 3
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- XBGGUPMXALFZOT-VIFPVBQESA-N Gly-Tyr Chemical compound NCC(=O)N[C@H](C(O)=O)CC1=CC=C(O)C=C1 XBGGUPMXALFZOT-VIFPVBQESA-N 0.000 claims description 2
- 108010044940 alanylglutamine Proteins 0.000 claims description 2
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- ALZVPLKYDKJKQU-XVKPBYJWSA-N Ala-Tyr Chemical compound C[C@H](N)C(=O)N[C@H](C(O)=O)CC1=CC=C(O)C=C1 ALZVPLKYDKJKQU-XVKPBYJWSA-N 0.000 claims 1
- PNMUAGGSDZXTHX-BYPYZUCNSA-N Gly-Gln Chemical compound NCC(=O)N[C@H](C(O)=O)CCC(N)=O PNMUAGGSDZXTHX-BYPYZUCNSA-N 0.000 claims 1
- 208000022559 Inflammatory bowel disease Diseases 0.000 claims 1
- 108010070783 alanyltyrosine Proteins 0.000 claims 1
- 229960002989 glutamic acid Drugs 0.000 claims 1
- XBGGUPMXALFZOT-UHFFFAOYSA-N glycyl-L-tyrosine hemihydrate Natural products NCC(=O)NC(C(O)=O)CC1=CC=C(O)C=C1 XBGGUPMXALFZOT-UHFFFAOYSA-N 0.000 claims 1
- 108010010147 glycylglutamine Proteins 0.000 claims 1
- 239000003978 infusion fluid Substances 0.000 claims 1
- ZDXPYRJPNDTMRX-VKHMYHEASA-N L-glutamine Chemical compound OC(=O)[C@@H](N)CCC(N)=O ZDXPYRJPNDTMRX-VKHMYHEASA-N 0.000 abstract description 8
- 229960004441 tyrosine Drugs 0.000 description 21
- 229960002433 cysteine Drugs 0.000 description 14
- 239000002243 precursor Substances 0.000 description 8
- WHUUTDBJXJRKMK-UHFFFAOYSA-N Glutamic acid Natural products OC(=O)C(N)CCC(O)=O WHUUTDBJXJRKMK-UHFFFAOYSA-N 0.000 description 7
- 235000013922 glutamic acid Nutrition 0.000 description 7
- 239000004220 glutamic acid Substances 0.000 description 7
- 108010016626 Dipeptides Proteins 0.000 description 6
- 206010036590 Premature baby Diseases 0.000 description 6
- 230000004060 metabolic process Effects 0.000 description 6
- DHMQDGOQFOQNFH-UHFFFAOYSA-N Glycine Chemical compound NCC(O)=O DHMQDGOQFOQNFH-UHFFFAOYSA-N 0.000 description 4
- 239000007857 degradation product Substances 0.000 description 4
- 238000011161 development Methods 0.000 description 4
- 230000018109 developmental process Effects 0.000 description 4
- RWSXRVCMGQZWBV-WDSKDSINSA-N glutathione Chemical compound OC(=O)[C@@H](N)CCC(=O)N[C@@H](CS)C(=O)NCC(O)=O RWSXRVCMGQZWBV-WDSKDSINSA-N 0.000 description 4
- 230000002028 premature Effects 0.000 description 4
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- 102100030840 AT-rich interactive domain-containing protein 4B Human genes 0.000 description 2
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 description 2
- 108010024636 Glutathione Proteins 0.000 description 2
- 239000004471 Glycine Substances 0.000 description 2
- 101000792935 Homo sapiens AT-rich interactive domain-containing protein 4B Proteins 0.000 description 2
- QNAYBMKLOCPYGJ-REOHCLBHSA-N L-alanine Chemical compound C[C@H](N)C(O)=O QNAYBMKLOCPYGJ-REOHCLBHSA-N 0.000 description 2
- CAHKINHBCWCHCF-UHFFFAOYSA-N N-acetyltyrosine Chemical compound CC(=O)NC(C(O)=O)CC1=CC=C(O)C=C1 CAHKINHBCWCHCF-UHFFFAOYSA-N 0.000 description 2
- 235000004279 alanine Nutrition 0.000 description 2
- -1 aromatic amino acids Chemical class 0.000 description 2
- 230000015556 catabolic process Effects 0.000 description 2
- 230000007812 deficiency Effects 0.000 description 2
- 238000006731 degradation reaction Methods 0.000 description 2
- VYFYYTLLBUKUHU-UHFFFAOYSA-N dopamine Chemical compound NCCC1=CC=C(O)C(O)=C1 VYFYYTLLBUKUHU-UHFFFAOYSA-N 0.000 description 2
- 239000003797 essential amino acid Substances 0.000 description 2
- 235000020776 essential amino acid Nutrition 0.000 description 2
- 229960002743 glutamine Drugs 0.000 description 2
- 125000000404 glutamine group Chemical group N[C@@H](CCC(N)=O)C(=O)* 0.000 description 2
- 229960003180 glutathione Drugs 0.000 description 2
- 230000012010 growth Effects 0.000 description 2
- 229940088597 hormone Drugs 0.000 description 2
- 239000005556 hormone Substances 0.000 description 2
- 238000000034 method Methods 0.000 description 2
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- 230000009467 reduction Effects 0.000 description 2
- 208000024891 symptom Diseases 0.000 description 2
- 235000021476 total parenteral nutrition Nutrition 0.000 description 2
- SFLSHLFXELFNJZ-QMMMGPOBSA-N (-)-norepinephrine Chemical compound NC[C@H](O)C1=CC=C(O)C(O)=C1 SFLSHLFXELFNJZ-QMMMGPOBSA-N 0.000 description 1
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 description 1
- 206010009900 Colitis ulcerative Diseases 0.000 description 1
- 208000011231 Crohn disease Diseases 0.000 description 1
- 102000020018 Cystathionine gamma-Lyase Human genes 0.000 description 1
- 108010045283 Cystathionine gamma-lyase Proteins 0.000 description 1
- XUIIKFGFIJCVMT-GFCCVEGCSA-N D-thyroxine Chemical compound IC1=CC(C[C@@H](N)C(O)=O)=CC(I)=C1OC1=CC(I)=C(O)C(I)=C1 XUIIKFGFIJCVMT-GFCCVEGCSA-N 0.000 description 1
- 206010012735 Diarrhoea Diseases 0.000 description 1
- 108090000790 Enzymes Proteins 0.000 description 1
- 102000004190 Enzymes Human genes 0.000 description 1
- 206010017877 Gastrointestinal fistula Diseases 0.000 description 1
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 1
- 206010061218 Inflammation Diseases 0.000 description 1
- PWKSKIMOESPYIA-BYPYZUCNSA-N L-N-acetyl-Cysteine Chemical compound CC(=O)N[C@@H](CS)C(O)=O PWKSKIMOESPYIA-BYPYZUCNSA-N 0.000 description 1
- 108010069013 Phenylalanine Hydroxylase Proteins 0.000 description 1
- 108010009736 Protein Hydrolysates Proteins 0.000 description 1
- 206010037211 Psychomotor hyperactivity Diseases 0.000 description 1
- 206010040047 Sepsis Diseases 0.000 description 1
- 206010049416 Short-bowel syndrome Diseases 0.000 description 1
- 201000006704 Ulcerative Colitis Diseases 0.000 description 1
- 230000037354 amino acid metabolism Effects 0.000 description 1
- 230000003698 anagen phase Effects 0.000 description 1
- 239000003963 antioxidant agent Substances 0.000 description 1
- 230000003078 antioxidant effect Effects 0.000 description 1
- 239000007864 aqueous solution Substances 0.000 description 1
- 150000005693 branched-chain amino acids Chemical class 0.000 description 1
- 235000021152 breakfast Nutrition 0.000 description 1
- 229910052791 calcium Inorganic materials 0.000 description 1
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- 230000030833 cell death Effects 0.000 description 1
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- 210000002249 digestive system Anatomy 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 229960003638 dopamine Drugs 0.000 description 1
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- 210000001035 gastrointestinal tract Anatomy 0.000 description 1
- 230000008571 general function Effects 0.000 description 1
- 239000008103 glucose Substances 0.000 description 1
- 210000000987 immune system Anatomy 0.000 description 1
- 230000002757 inflammatory effect Effects 0.000 description 1
- 230000004054 inflammatory process Effects 0.000 description 1
- 208000028774 intestinal disease Diseases 0.000 description 1
- 238000001990 intravenous administration Methods 0.000 description 1
- 210000004698 lymphocyte Anatomy 0.000 description 1
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- 210000000653 nervous system Anatomy 0.000 description 1
- 229910052757 nitrogen Inorganic materials 0.000 description 1
- 229960002748 norepinephrine Drugs 0.000 description 1
- SFLSHLFXELFNJZ-UHFFFAOYSA-N norepinephrine Natural products NCC(O)C1=CC=C(O)C(O)=C1 SFLSHLFXELFNJZ-UHFFFAOYSA-N 0.000 description 1
- 230000035764 nutrition Effects 0.000 description 1
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- 230000001991 pathophysiological effect Effects 0.000 description 1
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- 229940034208 thyroxine Drugs 0.000 description 1
- XUIIKFGFIJCVMT-UHFFFAOYSA-N thyroxine-binding globulin Natural products IC1=CC(CC([NH3+])C([O-])=O)=CC(I)=C1OC1=CC(I)=C(O)C(I)=C1 XUIIKFGFIJCVMT-UHFFFAOYSA-N 0.000 description 1
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0029—Parenteral nutrition; Parenteral nutrition compositions as drug carriers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
- A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/17—Amino acids, peptides or proteins
- A23L33/175—Amino acids
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/17—Amino acids, peptides or proteins
- A23L33/18—Peptides; Protein hydrolysates
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/40—Complete food formulations for specific consumer groups or specific purposes, e.g. infant formula
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/05—Dipeptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/02—Nutrients, e.g. vitamins, minerals
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Nutrition Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Polymers & Plastics (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Food Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Urology & Nephrology (AREA)
- Dermatology (AREA)
- Molecular Biology (AREA)
- Pediatric Medicine (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Priority Applications (16)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE102006018293A DE102006018293A1 (de) | 2006-04-20 | 2006-04-20 | Pädiatrische Aminosäurelösung zur parenteralen Ernäherung |
| MX2008013540A MX2008013540A (es) | 2006-04-20 | 2007-03-05 | Solucion de aminoacidos pediatrica para nutricion parenteral. |
| PCT/EP2007/001878 WO2007121807A1 (de) | 2006-04-20 | 2007-03-05 | Paediatrische aminosäurelösung zur parenteralen ernährung |
| AU2007241469A AU2007241469B2 (en) | 2006-04-20 | 2007-03-05 | Paediatric amino acid solution for parenteral nutrition |
| CA002647087A CA2647087A1 (en) | 2006-04-20 | 2007-03-05 | Paediatric amino acid solution for parenteral nutrition |
| BRPI0710298-4A BRPI0710298A2 (pt) | 2006-04-20 | 2007-03-05 | solução pediátrica de aminoácidos para nutrição parenteral |
| CNA2007800136921A CN101420933A (zh) | 2006-04-20 | 2007-03-05 | 用于胃肠外营养的儿科氨基酸溶液 |
| EA200870451A EA015709B1 (ru) | 2006-04-20 | 2007-03-05 | Педиатрический аминокислотный раствор для парентерального питания и его применение |
| KR1020087027628A KR20090010050A (ko) | 2006-04-20 | 2007-03-05 | 비경구적 영양법용 소아 아미노산액 |
| JP2009505732A JP2009534323A (ja) | 2006-04-20 | 2007-03-05 | 非経口栄養のための小児用アミノ酸溶液 |
| CN201410705858.8A CN104524542A (zh) | 2006-04-20 | 2007-03-05 | 用于胃肠外营养的儿科氨基酸溶液 |
| US12/226,358 US8377876B2 (en) | 2006-04-20 | 2007-03-05 | Pediatric amino acid solution for parenteral nutrition |
| EP07711788.5A EP2007348B1 (de) | 2006-04-20 | 2007-03-05 | Paediatrische aminosäurelösung zur parenteralen ernährung |
| TW096108010A TWI429405B (zh) | 2006-04-20 | 2007-03-08 | 用於靜脈營養療法的小兒胺基酸溶液 |
| ARP070101703A AR060555A1 (es) | 2006-04-20 | 2007-04-20 | Solucion de aminoacidos pediatrica para nutricion parenteral |
| ZA200807860A ZA200807860B (en) | 2006-04-20 | 2008-09-12 | Paediatric amino acid solution for parenteral nutrition |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE102006018293A DE102006018293A1 (de) | 2006-04-20 | 2006-04-20 | Pädiatrische Aminosäurelösung zur parenteralen Ernäherung |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE102006018293A1 true DE102006018293A1 (de) | 2007-10-25 |
Family
ID=38006821
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE102006018293A Ceased DE102006018293A1 (de) | 2006-04-20 | 2006-04-20 | Pädiatrische Aminosäurelösung zur parenteralen Ernäherung |
Country Status (15)
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| EP (1) | EP2007348B1 (enExample) |
| JP (1) | JP2009534323A (enExample) |
| KR (1) | KR20090010050A (enExample) |
| CN (2) | CN101420933A (enExample) |
| AR (1) | AR060555A1 (enExample) |
| AU (1) | AU2007241469B2 (enExample) |
| BR (1) | BRPI0710298A2 (enExample) |
| CA (1) | CA2647087A1 (enExample) |
| DE (1) | DE102006018293A1 (enExample) |
| EA (1) | EA015709B1 (enExample) |
| MX (1) | MX2008013540A (enExample) |
| TW (1) | TWI429405B (enExample) |
| WO (1) | WO2007121807A1 (enExample) |
| ZA (1) | ZA200807860B (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP4125436A4 (en) * | 2020-04-01 | 2024-05-15 | The E. Wolfson Medical Center | ULCEROUS COLITIS DIET, RELATED FORMULAS, PRODUCTS AND METHODS |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102065698A (zh) | 2008-06-19 | 2011-05-18 | 荷兰联合利华有限公司 | 具有铁和锌的含脂肪食用乳液 |
| AU2009268742C1 (en) | 2008-07-07 | 2013-11-28 | Pentec Health, Inc. | Nutritive compositions and methods of using same |
| JP2011121889A (ja) * | 2009-12-09 | 2011-06-23 | En Otsuka Pharmaceutical Co Ltd | 炎症性腸疾患用アミノ酸組成物 |
| CA2786375A1 (en) * | 2010-01-04 | 2011-07-07 | Pentec Health, Inc. | Nutritive compositions and methods of using same |
| JP2011144116A (ja) * | 2010-01-12 | 2011-07-28 | En Otsuka Pharmaceutical Co Ltd | 炎症性腸疾患用添加剤 |
| US20110208153A1 (en) * | 2010-02-24 | 2011-08-25 | John Alvey | Formulations and methods for nutrient delivery |
| JP6000253B2 (ja) | 2010-09-24 | 2016-09-28 | ユニバーシティ オブ フロリダ リサーチ ファンデーション インコーポレーティッド | 胃腸機能を改善するための材料および方法 |
| EP2489408A1 (de) * | 2011-01-13 | 2012-08-22 | Michael Tchirikov | Aminosäurezusammensetzung und deren Verwendung zur Behandlung von fetaler Wachstumsrestriktion (IUGR) und zur parenteralen Ernährung von extrem Frühgeborenen |
| CN104039174B (zh) * | 2012-01-09 | 2016-11-16 | N·V·努特里奇亚 | 用于早产婴儿的富含谷氨酰胺的营养组合物 |
| MX368543B (es) * | 2012-02-08 | 2019-10-07 | Univ Florida | Composiciones para tratar diarrea inducida por rotavirus. |
| BR112015016465B1 (pt) * | 2013-01-09 | 2020-11-10 | N.V. Nutricia | uso de glutamina ou de uma composição; método não-medicinal para melhora posterior da função cognitiva em um bebê muito prematuro nascido pequeno para a idade gestacional; e método não-medicinal para melhora posterior do q.i em um bebê muito prematuro nascido pequeno para a idade gestacional |
| WO2014164736A1 (en) | 2013-03-11 | 2014-10-09 | University Of Florida Research Foundation, Incorporated | Materials and methods for improving lung function and for prevention and/or treatment of radiation-induced lung complications |
| CN103404934B (zh) * | 2013-08-24 | 2015-07-01 | 江苏阜丰生物科技有限公司 | 一种含谷氨酰胺的解酒固体饮料及其制备方法 |
| WO2015178762A1 (en) * | 2014-05-19 | 2015-11-26 | N.V. Nutricia | Enteral formulations for preterm infants comprising optimised phenylalanine intake levels |
| WO2015178761A1 (en) | 2014-05-19 | 2015-11-26 | N.V. Nutricia | Formulas comprising optimised amino acid profiles |
| JOP20190276A1 (ar) * | 2017-05-31 | 2019-11-27 | Napo Pharmaceuticals Inc | طرق وتركيبات لعلاج إسهال الحمض الصفراوي، والإسهال المرتبط باستئصال الأمعاء الدقيقة أو إزالة المرارة، ومتلازمة الأمعاء القصيرة |
| CN107898808B (zh) * | 2017-10-31 | 2021-04-27 | 华仁药业股份有限公司 | 小儿用静脉营养制剂 |
| RU2699222C1 (ru) * | 2019-04-29 | 2019-09-04 | Алексей Владимирович Воронов | Солевой электролитный раствор для проведения энтеральных инфузий |
| US20220378077A1 (en) * | 2021-05-25 | 2022-12-01 | Baxter International Inc. | Ready-To-Use Parenteral Nutrition Formulation |
| IT202200015885A1 (it) * | 2022-07-27 | 2024-01-27 | St G Gaslini | Sacca standardizzata per alimentazione di nati pretermine e dispositivo di alimentazione di nati pretermine |
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| EP0087750A2 (de) * | 1982-02-25 | 1983-09-07 | Kabi Pharmacia GmbH | Glutaminhaltige Aminosäure-Zubereitungen |
| WO1991016067A1 (en) * | 1990-04-23 | 1991-10-31 | Research Corporation Technologies, Inc. | Soluble and stable sources of tyrosine, cysteine and glutamine for total parenteral nutrition |
| US5504072A (en) * | 1993-10-08 | 1996-04-02 | Sandoz Nutrition Ltd. | Enteral nutritional composition having balanced amino acid profile |
| DE69430416T2 (de) * | 1993-10-28 | 2002-12-05 | Institut National De La Recherche Agronomique, Paris | Zusammensetzungen aus Aminosäure zur Behandlung von Infektionen |
| EP1065947B1 (en) * | 1998-03-31 | 2003-04-23 | Societe Des Produits Nestle S.A. | Use of a composition for providing glutamine |
Family Cites Families (10)
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| FR2556594B1 (fr) * | 1983-12-20 | 1988-09-09 | Synthelabo | Solutions d'acides amines |
| US5684045A (en) * | 1985-09-12 | 1997-11-04 | Brigham And Women's Hospital | Method of treating pancreatic atrophy |
| JPH0710770A (ja) * | 1990-03-14 | 1995-01-13 | Otsuka Pharmaceut Factory Inc | アミノ酸輸液 |
| US5206220A (en) * | 1990-04-23 | 1993-04-27 | Research Corporation Technologies, Inc. | Soluble and stable sources of tyrosine, cysteine and glutamine for total parenteral nutrition |
| SE9003844L (sv) * | 1990-12-03 | 1992-06-04 | Kabi Pharmacia Ab | Naeringstillsats |
| JPH06227974A (ja) * | 1993-01-29 | 1994-08-16 | Kyowa Hakko Kogyo Co Ltd | 栄養組成物 |
| US5719133A (en) * | 1994-09-21 | 1998-02-17 | Novartis Nutrition Ag | Adolescent dietary composition |
| US5561111A (en) * | 1994-12-23 | 1996-10-01 | The University Of Virginia Patent Foundation | Stable glutamine derivatives for oral and intravenous rehydration and nutrition therapy |
| US6080788A (en) * | 1997-03-27 | 2000-06-27 | Sole; Michael J. | Composition for improvement of cellular nutrition and mitochondrial energetics |
| US7148199B2 (en) * | 2003-09-26 | 2006-12-12 | University Of Florida Research Foundation, Inc. | Arginyl-glutamine dipeptide for treatment of pathological vascular proliferation |
-
2006
- 2006-04-20 DE DE102006018293A patent/DE102006018293A1/de not_active Ceased
-
2007
- 2007-03-05 WO PCT/EP2007/001878 patent/WO2007121807A1/de not_active Ceased
- 2007-03-05 AU AU2007241469A patent/AU2007241469B2/en not_active Ceased
- 2007-03-05 CA CA002647087A patent/CA2647087A1/en not_active Abandoned
- 2007-03-05 JP JP2009505732A patent/JP2009534323A/ja active Pending
- 2007-03-05 CN CNA2007800136921A patent/CN101420933A/zh active Pending
- 2007-03-05 CN CN201410705858.8A patent/CN104524542A/zh active Pending
- 2007-03-05 US US12/226,358 patent/US8377876B2/en not_active Expired - Fee Related
- 2007-03-05 MX MX2008013540A patent/MX2008013540A/es active IP Right Grant
- 2007-03-05 BR BRPI0710298-4A patent/BRPI0710298A2/pt not_active IP Right Cessation
- 2007-03-05 EA EA200870451A patent/EA015709B1/ru not_active IP Right Cessation
- 2007-03-05 KR KR1020087027628A patent/KR20090010050A/ko not_active Withdrawn
- 2007-03-05 EP EP07711788.5A patent/EP2007348B1/de not_active Not-in-force
- 2007-03-08 TW TW096108010A patent/TWI429405B/zh not_active IP Right Cessation
- 2007-04-20 AR ARP070101703A patent/AR060555A1/es unknown
-
2008
- 2008-09-12 ZA ZA200807860A patent/ZA200807860B/xx unknown
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0087750A2 (de) * | 1982-02-25 | 1983-09-07 | Kabi Pharmacia GmbH | Glutaminhaltige Aminosäure-Zubereitungen |
| WO1991016067A1 (en) * | 1990-04-23 | 1991-10-31 | Research Corporation Technologies, Inc. | Soluble and stable sources of tyrosine, cysteine and glutamine for total parenteral nutrition |
| US5504072A (en) * | 1993-10-08 | 1996-04-02 | Sandoz Nutrition Ltd. | Enteral nutritional composition having balanced amino acid profile |
| US5504072B1 (en) * | 1993-10-08 | 1997-08-26 | Sandoz Nutrition Ltd | Enteral nutritional composition having balanced amino acid profile |
| DE69430416T2 (de) * | 1993-10-28 | 2002-12-05 | Institut National De La Recherche Agronomique, Paris | Zusammensetzungen aus Aminosäure zur Behandlung von Infektionen |
| EP1065947B1 (en) * | 1998-03-31 | 2003-04-23 | Societe Des Produits Nestle S.A. | Use of a composition for providing glutamine |
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| FÜRST, P. [u.a.]: Amino-Acid Substrates in New Bottles: Implications for Clinical Nutrition in the 21st Century, In: Nutrition (2000), Vol. 16, S. 603-606 * |
| FÜRST, P.: New Developments in Glutamine Delivery, In: J. Nutr. (2001), Vol. 131, Nr. 9 (Suppl.), S. 2562S-2568S * |
| HAYNES, T.E. [u.a.]: Glutamine prevents hydrogen peroxide-induced enterocyte death, In: FASEB Journal (2004), Vol. 18, S. A476., Abstr. 339.5 * |
| KALHAN, S.C. [u.a.]: Glutamine Supplement with Parenteral Nutrition Decreases Whole Body Proteo- lysis in Low Birth Weight Infants, In: J. Pediatr. (2005), Vol. 146, S. 642-647 |
| KALHAN, S.C. [u.a.]: Glutamine Supplement with Parenteral Nutrition Decreases Whole Body Proteolysis in Low Birth Weight Infants, In: J. Pediatr. (2005), Vol. 146, S. 642-647 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP4125436A4 (en) * | 2020-04-01 | 2024-05-15 | The E. Wolfson Medical Center | ULCEROUS COLITIS DIET, RELATED FORMULAS, PRODUCTS AND METHODS |
Also Published As
| Publication number | Publication date |
|---|---|
| EA015709B1 (ru) | 2011-10-31 |
| BRPI0710298A2 (pt) | 2011-08-09 |
| US20090203626A1 (en) | 2009-08-13 |
| EA200870451A1 (ru) | 2009-04-28 |
| AR060555A1 (es) | 2008-06-25 |
| WO2007121807A1 (de) | 2007-11-01 |
| JP2009534323A (ja) | 2009-09-24 |
| US8377876B2 (en) | 2013-02-19 |
| MX2008013540A (es) | 2008-10-31 |
| CN104524542A (zh) | 2015-04-22 |
| CN101420933A (zh) | 2009-04-29 |
| ZA200807860B (en) | 2009-08-26 |
| EP2007348B1 (de) | 2014-12-10 |
| KR20090010050A (ko) | 2009-01-28 |
| TWI429405B (zh) | 2014-03-11 |
| AU2007241469A1 (en) | 2007-11-01 |
| EP2007348A1 (de) | 2008-12-31 |
| CA2647087A1 (en) | 2007-11-01 |
| AU2007241469B2 (en) | 2012-09-20 |
| TW200740380A (en) | 2007-11-01 |
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