DE10044420A1 - Wirkstoffträger zur anhaltenden Wirkstofffreisetzung und Verfahren zu dessen Herstellung - Google Patents

Wirkstoffträger zur anhaltenden Wirkstofffreisetzung und Verfahren zu dessen Herstellung

Info

Publication number
DE10044420A1
DE10044420A1 DE10044420A DE10044420A DE10044420A1 DE 10044420 A1 DE10044420 A1 DE 10044420A1 DE 10044420 A DE10044420 A DE 10044420A DE 10044420 A DE10044420 A DE 10044420A DE 10044420 A1 DE10044420 A1 DE 10044420A1
Authority
DE
Germany
Prior art keywords
ceramic
active ingredient
carrier
depot
bodies
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
DE10044420A
Other languages
German (de)
English (en)
Inventor
Asako Matsushima
Masanori Nakasu
Makoto Otsuka
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hoya Corp
Original Assignee
Asahi Kogaku Kogyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Asahi Kogaku Kogyo Co Ltd filed Critical Asahi Kogaku Kogyo Co Ltd
Publication of DE10044420A1 publication Critical patent/DE10044420A1/de
Withdrawn legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2009Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/02Inorganic materials
    • A61L31/026Ceramic or ceramic-like structures, e.g. glasses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/16Biologically active materials, e.g. therapeutic substances
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/60Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
    • A61L2300/602Type of release, e.g. controlled, sustained, slow

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Surgery (AREA)
  • Biomedical Technology (AREA)
  • Inorganic Chemistry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Vascular Medicine (AREA)
  • Dermatology (AREA)
  • Neurosurgery (AREA)
  • Ceramic Engineering (AREA)
  • Molecular Biology (AREA)
  • Medicinal Preparation (AREA)
  • Materials For Medical Uses (AREA)
  • Ceramic Products (AREA)
DE10044420A 1999-09-08 2000-09-08 Wirkstoffträger zur anhaltenden Wirkstofffreisetzung und Verfahren zu dessen Herstellung Withdrawn DE10044420A1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP25447099A JP4172883B2 (ja) 1999-09-08 1999-09-08 薬物徐放用担体および薬物徐放用担体の製造方法

Publications (1)

Publication Number Publication Date
DE10044420A1 true DE10044420A1 (de) 2001-03-15

Family

ID=17265495

Family Applications (1)

Application Number Title Priority Date Filing Date
DE10044420A Withdrawn DE10044420A1 (de) 1999-09-08 2000-09-08 Wirkstoffträger zur anhaltenden Wirkstofffreisetzung und Verfahren zu dessen Herstellung

Country Status (4)

Country Link
US (1) US6719989B1 (enExample)
JP (1) JP4172883B2 (enExample)
DE (1) DE10044420A1 (enExample)
GB (1) GB2356140B (enExample)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10320772A1 (de) * 2003-05-09 2004-12-09 B. Braun Meisungen Ag Verfahren zur Abgabe von an einem Stent angebrachten Wirkstoff an einen menschlichen oder tierischen Körper und Stent hierfür
DE10320773A1 (de) * 2003-05-09 2004-12-16 B. Braun Melsungen Ag Verfahren zur Abgabe von an einem Stent angebrachten Wirkstoffen an einen menschlichen oder tierischen Körper und Stent hierfür

Families Citing this family (114)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8172897B2 (en) 1997-04-15 2012-05-08 Advanced Cardiovascular Systems, Inc. Polymer and metal composite implantable medical devices
US10028851B2 (en) 1997-04-15 2018-07-24 Advanced Cardiovascular Systems, Inc. Coatings for controlling erosion of a substrate of an implantable medical device
US6240616B1 (en) 1997-04-15 2001-06-05 Advanced Cardiovascular Systems, Inc. Method of manufacturing a medicated porous metal prosthesis
US6776792B1 (en) 1997-04-24 2004-08-17 Advanced Cardiovascular Systems Inc. Coated endovascular stent
US6840995B2 (en) 1999-07-14 2005-01-11 Calcitec, Inc. Process for producing fast-setting, bioresorbable calcium phosphate cements
US7270705B2 (en) * 1999-07-14 2007-09-18 Jiin-Huey Chern Lin Method of increasing working time of tetracalcium phosphate cement paste
US7169373B2 (en) * 1999-07-14 2007-01-30 Calcitec, Inc. Tetracalcium phosphate (TTCP) having calcium phosphate whisker on surface and process for preparing the same
US6960249B2 (en) * 1999-07-14 2005-11-01 Calcitec, Inc. Tetracalcium phosphate (TTCP) having calcium phosphate whisker on surface
US7094282B2 (en) * 2000-07-13 2006-08-22 Calcitec, Inc. Calcium phosphate cement, use and preparation thereof
AUPQ573300A0 (en) * 2000-02-21 2000-03-16 Australian Nuclear Science & Technology Organisation Controlled release ceramic particles, compositions thereof, processes of preparation and methods of use
ITVI20000025U1 (it) * 2000-04-07 2001-10-07 Tecres Spa Dispositivo distanziatore temporaneo per il trattamento chirurgico del ginocchio
US7156915B2 (en) * 2000-07-13 2007-01-02 Calcitec, Inc. Tetracalcium phosphate (TTCP) with surface whiskers and method of making same
US7204876B2 (en) * 2000-07-13 2007-04-17 Calcitec, Inc. Calcium phosphate cements made from (TTCP) with surface whiskers and process for preparing same
US6783793B1 (en) 2000-10-26 2004-08-31 Advanced Cardiovascular Systems, Inc. Selective coating of medical devices
WO2004026111A2 (en) 2000-11-16 2004-04-01 Microspherix Llc Flexible and/or elastic brachytherapy seed or strand
JP4070951B2 (ja) * 2000-12-07 2008-04-02 ペンタックス株式会社 多孔質リン酸カルシウム系セラミックス焼結体の製造方法
US20030078660A1 (en) * 2001-02-15 2003-04-24 Dale Clifford Orthopedic implant and method for orthopedic treatment
US6565659B1 (en) 2001-06-28 2003-05-20 Advanced Cardiovascular Systems, Inc. Stent mounting assembly and a method of using the same to coat a stent
US7989018B2 (en) 2001-09-17 2011-08-02 Advanced Cardiovascular Systems, Inc. Fluid treatment of a polymeric coating on an implantable medical device
US7285304B1 (en) 2003-06-25 2007-10-23 Advanced Cardiovascular Systems, Inc. Fluid treatment of a polymeric coating on an implantable medical device
US6863683B2 (en) 2001-09-19 2005-03-08 Abbott Laboratoris Vascular Entities Limited Cold-molding process for loading a stent onto a stent delivery system
US20030216777A1 (en) * 2002-05-16 2003-11-20 Yin-Chun Tien Method of enhancing healing of interfacial gap between bone and tendon or ligament
US8435550B2 (en) 2002-12-16 2013-05-07 Abbot Cardiovascular Systems Inc. Anti-proliferative and anti-inflammatory agent combination for treatment of vascular disorders with an implantable medical device
US7758881B2 (en) 2004-06-30 2010-07-20 Advanced Cardiovascular Systems, Inc. Anti-proliferative and anti-inflammatory agent combination for treatment of vascular disorders with an implantable medical device
JP2005046530A (ja) * 2003-07-31 2005-02-24 National Institute Of Advanced Industrial & Technology 多孔質リン酸カルシウム硬化体、その製造方法及びそれを用いた人工骨及び薬剤徐放体
US6994726B2 (en) * 2004-05-25 2006-02-07 Calcitec, Inc. Dual function prosthetic bone implant and method for preparing the same
US7163651B2 (en) * 2004-02-19 2007-01-16 Calcitec, Inc. Method for making a porous calcium phosphate article
US7198675B2 (en) 2003-09-30 2007-04-03 Advanced Cardiovascular Systems Stent mandrel fixture and method for selectively coating surfaces of a stent
US7563324B1 (en) 2003-12-29 2009-07-21 Advanced Cardiovascular Systems Inc. System and method for coating an implantable medical device
US7553377B1 (en) 2004-04-27 2009-06-30 Advanced Cardiovascular Systems, Inc. Apparatus and method for electrostatic coating of an abluminal stent surface
US8568469B1 (en) 2004-06-28 2013-10-29 Advanced Cardiovascular Systems, Inc. Stent locking element and a method of securing a stent on a delivery system
US8241554B1 (en) 2004-06-29 2012-08-14 Advanced Cardiovascular Systems, Inc. Method of forming a stent pattern on a tube
US8778256B1 (en) 2004-09-30 2014-07-15 Advanced Cardiovascular Systems, Inc. Deformation of a polymer tube in the fabrication of a medical article
US7731890B2 (en) 2006-06-15 2010-06-08 Advanced Cardiovascular Systems, Inc. Methods of fabricating stents with enhanced fracture toughness
US8747878B2 (en) 2006-04-28 2014-06-10 Advanced Cardiovascular Systems, Inc. Method of fabricating an implantable medical device by controlling crystalline structure
US8747879B2 (en) 2006-04-28 2014-06-10 Advanced Cardiovascular Systems, Inc. Method of fabricating an implantable medical device to reduce chance of late inflammatory response
US7971333B2 (en) 2006-05-30 2011-07-05 Advanced Cardiovascular Systems, Inc. Manufacturing process for polymetric stents
US8541028B2 (en) * 2004-08-04 2013-09-24 Evonik Corporation Methods for manufacturing delivery devices and devices thereof
US9283099B2 (en) 2004-08-25 2016-03-15 Advanced Cardiovascular Systems, Inc. Stent-catheter assembly with a releasable connection for stent retention
US7229471B2 (en) 2004-09-10 2007-06-12 Advanced Cardiovascular Systems, Inc. Compositions containing fast-leaching plasticizers for improved performance of medical devices
US8043553B1 (en) 2004-09-30 2011-10-25 Advanced Cardiovascular Systems, Inc. Controlled deformation of a polymer tube with a restraining surface in fabricating a medical article
US8173062B1 (en) 2004-09-30 2012-05-08 Advanced Cardiovascular Systems, Inc. Controlled deformation of a polymer tube in fabricating a medical article
US7875233B2 (en) 2004-09-30 2011-01-25 Advanced Cardiovascular Systems, Inc. Method of fabricating a biaxially oriented implantable medical device
EP1812090A1 (en) * 2004-10-28 2007-08-01 Microchips, Inc. Orthopedic and dental implant devices providing controlled drug delivery
US7632307B2 (en) 2004-12-16 2009-12-15 Advanced Cardiovascular Systems, Inc. Abluminal, multilayer coating constructs for drug-delivery stents
US7381048B2 (en) 2005-04-12 2008-06-03 Advanced Cardiovascular Systems, Inc. Stents with profiles for gripping a balloon catheter and molds for fabricating stents
US20060247623A1 (en) * 2005-04-29 2006-11-02 Sdgi Holdings, Inc. Local delivery of an active agent from an orthopedic implant
US7291166B2 (en) 2005-05-18 2007-11-06 Advanced Cardiovascular Systems, Inc. Polymeric stent patterns
US7531190B2 (en) * 2005-05-25 2009-05-12 Biomet Manufacturing Corp. Porous ceramic structure containing biologics
US7622070B2 (en) 2005-06-20 2009-11-24 Advanced Cardiovascular Systems, Inc. Method of manufacturing an implantable polymeric medical device
WO2007001624A2 (en) * 2005-06-28 2007-01-04 Microchips, Inc. Medical and dental implant devices for controlled drug delivery
US7658880B2 (en) 2005-07-29 2010-02-09 Advanced Cardiovascular Systems, Inc. Polymeric stent polishing method and apparatus
US7297758B2 (en) 2005-08-02 2007-11-20 Advanced Cardiovascular Systems, Inc. Method for extending shelf-life of constructs of semi-crystallizable polymers
US7476245B2 (en) 2005-08-16 2009-01-13 Advanced Cardiovascular Systems, Inc. Polymeric stent patterns
US9248034B2 (en) 2005-08-23 2016-02-02 Advanced Cardiovascular Systems, Inc. Controlled disintegrating implantable medical devices
US7867547B2 (en) 2005-12-19 2011-01-11 Advanced Cardiovascular Systems, Inc. Selectively coating luminal surfaces of stents
US20070156230A1 (en) 2006-01-04 2007-07-05 Dugan Stephen R Stents with radiopaque markers
US7951185B1 (en) 2006-01-06 2011-05-31 Advanced Cardiovascular Systems, Inc. Delivery of a stent at an elevated temperature
DE602007012654D1 (de) * 2006-01-13 2011-04-07 Barry M Fell Chirurgisch implantierbare prothese mit einer aktiven komponente
US7964210B2 (en) 2006-03-31 2011-06-21 Abbott Cardiovascular Systems Inc. Degradable polymeric implantable medical devices with a continuous phase and discrete phase
US8003156B2 (en) 2006-05-04 2011-08-23 Advanced Cardiovascular Systems, Inc. Rotatable support elements for stents
US7761968B2 (en) 2006-05-25 2010-07-27 Advanced Cardiovascular Systems, Inc. Method of crimping a polymeric stent
US20130325104A1 (en) 2006-05-26 2013-12-05 Abbott Cardiovascular Systems Inc. Stents With Radiopaque Markers
US7951194B2 (en) 2006-05-26 2011-05-31 Abbott Cardiovascular Sysetms Inc. Bioabsorbable stent with radiopaque coating
US8343530B2 (en) 2006-05-30 2013-01-01 Abbott Cardiovascular Systems Inc. Polymer-and polymer blend-bioceramic composite implantable medical devices
US7959940B2 (en) 2006-05-30 2011-06-14 Advanced Cardiovascular Systems, Inc. Polymer-bioceramic composite implantable medical devices
US7842737B2 (en) 2006-09-29 2010-11-30 Abbott Cardiovascular Systems Inc. Polymer blend-bioceramic composite implantable medical devices
US8486135B2 (en) 2006-06-01 2013-07-16 Abbott Cardiovascular Systems Inc. Implantable medical devices fabricated from branched polymers
US8034287B2 (en) 2006-06-01 2011-10-11 Abbott Cardiovascular Systems Inc. Radiation sterilization of medical devices
US8603530B2 (en) 2006-06-14 2013-12-10 Abbott Cardiovascular Systems Inc. Nanoshell therapy
US8048448B2 (en) 2006-06-15 2011-11-01 Abbott Cardiovascular Systems Inc. Nanoshells for drug delivery
US8535372B1 (en) 2006-06-16 2013-09-17 Abbott Cardiovascular Systems Inc. Bioabsorbable stent with prohealing layer
US8333000B2 (en) 2006-06-19 2012-12-18 Advanced Cardiovascular Systems, Inc. Methods for improving stent retention on a balloon catheter
US8017237B2 (en) 2006-06-23 2011-09-13 Abbott Cardiovascular Systems, Inc. Nanoshells on polymers
US9072820B2 (en) 2006-06-26 2015-07-07 Advanced Cardiovascular Systems, Inc. Polymer composite stent with polymer particles
US8128688B2 (en) 2006-06-27 2012-03-06 Abbott Cardiovascular Systems Inc. Carbon coating on an implantable device
US7794776B1 (en) 2006-06-29 2010-09-14 Abbott Cardiovascular Systems Inc. Modification of polymer stents with radiation
US7740791B2 (en) 2006-06-30 2010-06-22 Advanced Cardiovascular Systems, Inc. Method of fabricating a stent with features by blow molding
US7823263B2 (en) 2006-07-11 2010-11-02 Abbott Cardiovascular Systems Inc. Method of removing stent islands from a stent
US7998404B2 (en) 2006-07-13 2011-08-16 Advanced Cardiovascular Systems, Inc. Reduced temperature sterilization of stents
US7757543B2 (en) 2006-07-13 2010-07-20 Advanced Cardiovascular Systems, Inc. Radio frequency identification monitoring of stents
US7794495B2 (en) 2006-07-17 2010-09-14 Advanced Cardiovascular Systems, Inc. Controlled degradation of stents
US7886419B2 (en) 2006-07-18 2011-02-15 Advanced Cardiovascular Systems, Inc. Stent crimping apparatus and method
US8016879B2 (en) 2006-08-01 2011-09-13 Abbott Cardiovascular Systems Inc. Drug delivery after biodegradation of the stent scaffolding
US9173733B1 (en) 2006-08-21 2015-11-03 Abbott Cardiovascular Systems Inc. Tracheobronchial implantable medical device and methods of use
US7923022B2 (en) 2006-09-13 2011-04-12 Advanced Cardiovascular Systems, Inc. Degradable polymeric implantable medical devices with continuous phase and discrete phase
US8099849B2 (en) 2006-12-13 2012-01-24 Abbott Cardiovascular Systems Inc. Optimizing fracture toughness of polymeric stent
US8262723B2 (en) 2007-04-09 2012-09-11 Abbott Cardiovascular Systems Inc. Implantable medical devices fabricated from polymer blends with star-block copolymers
US7829008B2 (en) 2007-05-30 2010-11-09 Abbott Cardiovascular Systems Inc. Fabricating a stent from a blow molded tube
US7959857B2 (en) 2007-06-01 2011-06-14 Abbott Cardiovascular Systems Inc. Radiation sterilization of medical devices
US8293260B2 (en) 2007-06-05 2012-10-23 Abbott Cardiovascular Systems Inc. Elastomeric copolymer coatings containing poly (tetramethyl carbonate) for implantable medical devices
US8202528B2 (en) 2007-06-05 2012-06-19 Abbott Cardiovascular Systems Inc. Implantable medical devices with elastomeric block copolymer coatings
US8425591B1 (en) 2007-06-11 2013-04-23 Abbott Cardiovascular Systems Inc. Methods of forming polymer-bioceramic composite medical devices with bioceramic particles
US8048441B2 (en) 2007-06-25 2011-11-01 Abbott Cardiovascular Systems, Inc. Nanobead releasing medical devices
US7901452B2 (en) 2007-06-27 2011-03-08 Abbott Cardiovascular Systems Inc. Method to fabricate a stent having selected morphology to reduce restenosis
US7955381B1 (en) 2007-06-29 2011-06-07 Advanced Cardiovascular Systems, Inc. Polymer-bioceramic composite implantable medical device with different types of bioceramic particles
ES2718612T3 (es) 2007-12-20 2019-07-03 Evonik Corp Procedimiento para preparar micropartículas que tienen un bajo volumen de disolvente residual
US20100068233A1 (en) * 2008-09-16 2010-03-18 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Modifiable dosage form
US20100068152A1 (en) * 2008-09-16 2010-03-18 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Ex vivo modifiable particle or polymeric based final dosage form
US20100068254A1 (en) * 2008-09-16 2010-03-18 Mahalaxmi Gita Bangera Modifying a medicament availability state of a final dosage form
US20100068153A1 (en) * 2008-09-16 2010-03-18 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Ex vivo activatable final dosage form
US20100068278A1 (en) * 2008-09-16 2010-03-18 Searete Llc, A Limited Liablity Corporation Of The State Of Delaware Ex vivo modifiable medicament release-associations
US20100068275A1 (en) * 2008-09-16 2010-03-18 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Personalizable dosage form
US20100069821A1 (en) * 2008-09-16 2010-03-18 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Ex vivo modifiable medicament release-sites final dosage form
US20100068235A1 (en) * 2008-09-16 2010-03-18 Searete LLC, a limited liability corporation of Deleware Individualizable dosage form
US8808353B2 (en) 2010-01-30 2014-08-19 Abbott Cardiovascular Systems Inc. Crush recoverable polymer scaffolds having a low crossing profile
US8568471B2 (en) 2010-01-30 2013-10-29 Abbott Cardiovascular Systems Inc. Crush recoverable polymer scaffolds
US8726483B2 (en) 2011-07-29 2014-05-20 Abbott Cardiovascular Systems Inc. Methods for uniform crimping and deployment of a polymer scaffold
KR101265783B1 (ko) 2011-09-28 2013-05-20 주식회사 코렌텍 생리활성물질의 담지가 가능한 임플란트 및 그 제조방법
US9999527B2 (en) 2015-02-11 2018-06-19 Abbott Cardiovascular Systems Inc. Scaffolds having radiopaque markers
US9700443B2 (en) 2015-06-12 2017-07-11 Abbott Cardiovascular Systems Inc. Methods for attaching a radiopaque marker to a scaffold
CN105251060B (zh) * 2015-10-29 2019-04-16 中国科学院宁波材料技术与工程研究所 一种利用真空冷喷涂技术制备药物缓释涂层的方法及其产品
US10537658B2 (en) 2017-03-28 2020-01-21 DePuy Synthes Products, Inc. Orthopedic implant having a crystalline gallium-containing hydroxyapatite coating and methods for making the same
US10537661B2 (en) 2017-03-28 2020-01-21 DePuy Synthes Products, Inc. Orthopedic implant having a crystalline calcium phosphate coating and methods for making the same

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4218255A (en) * 1976-08-30 1980-08-19 University Of Dayton Porous ceramic carriers for controlled release of proteins, polypeptide hormones, and other substances within human and/or other mamillian species and method
JPS55122710A (en) * 1979-02-13 1980-09-20 Kyocera Corp Ceramic small granule for drug administration
JPS59101145A (ja) * 1982-11-30 1984-06-11 日本特殊陶業株式会社 薬液含浸多孔質セラミツクス
JPS6131163A (ja) * 1984-07-23 1986-02-13 京セラ株式会社 セラミツク製生体補綴材とその製造方法
JPS6440418A (en) * 1987-08-07 1989-02-10 Arusu Japan Kk Sustained release material for drug
EP0313090B1 (en) 1987-10-22 1994-03-02 Asahi Kogaku Kogyo Kabushiki Kaisha Porous ceramic material
US5055307A (en) 1988-12-29 1991-10-08 Asahi Kagaku Kogyo Kabushiki Kaisha Slow release drug delivery granules and process for production thereof
JPH03161429A (ja) * 1989-11-20 1991-07-11 Olympus Optical Co Ltd 薬物徐放材
JPH041123A (ja) * 1990-04-16 1992-01-06 Olympus Optical Co Ltd 薬物徐放材
JP3122669B2 (ja) * 1990-12-26 2001-01-09 オリンパス光学工業株式会社 徐放剤およびその製造方法
US5645596A (en) * 1993-07-07 1997-07-08 Asahi Kogaku Kogyo Kabushiki Kaisha Ceramic vertebrae prosthesis
CH686518A5 (de) 1993-10-05 1996-04-15 Asahi Optical Co Ltd Granulares Polymerkomposit, Herstellungsverfahren fur dieses und diagnostische Mittel.
JPH0930988A (ja) * 1995-07-21 1997-02-04 Sumitomo Osaka Cement Co Ltd 薬剤徐放性多孔質セラミックス成形体及びその製造方法
US5783248A (en) * 1995-08-28 1998-07-21 National Science Council Of R.O.C. Process for producing a bioceramic composite material containing natural bone material on an alumina substrate
JPH09145713A (ja) 1995-11-21 1997-06-06 Asahi Optical Co Ltd 抗原又は抗体の検査材の評価方法
JP3600676B2 (ja) 1996-01-29 2004-12-15 ペンタックス株式会社 生体内可溶性複合体粒子
WO1998017330A1 (en) * 1996-10-24 1998-04-30 Sdgi Holdings, Inc. Ceramic fusion implants and compositions containing osteoinductive factors
AU6499898A (en) * 1997-03-04 1998-09-22 Implico B.V. An artefact suitable for use as a bone implant
JPH10279471A (ja) * 1997-04-07 1998-10-20 Asahi Optical Co Ltd 多孔質リン酸カルシウム系焼結体ブロックへの薬剤の含浸法
US5919473A (en) 1997-05-12 1999-07-06 Elkhoury; George F. Methods and devices for delivering opioid analgesics to wounds via a subdermal implant

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10320772A1 (de) * 2003-05-09 2004-12-09 B. Braun Meisungen Ag Verfahren zur Abgabe von an einem Stent angebrachten Wirkstoff an einen menschlichen oder tierischen Körper und Stent hierfür
DE10320773A1 (de) * 2003-05-09 2004-12-16 B. Braun Melsungen Ag Verfahren zur Abgabe von an einem Stent angebrachten Wirkstoffen an einen menschlichen oder tierischen Körper und Stent hierfür
DE10320773A8 (de) * 2003-05-09 2005-05-19 B. Braun Melsungen Ag Verfahren zur Abgabe von an einem Stent angebrachten Wirkstoffen an einen menschlichen oder tierischen Körper und Stent hierfür

Also Published As

Publication number Publication date
GB2356140B (en) 2004-03-17
US6719989B1 (en) 2004-04-13
JP2001072577A (ja) 2001-03-21
GB0022086D0 (en) 2000-10-25
JP4172883B2 (ja) 2008-10-29
GB2356140A (en) 2001-05-16

Similar Documents

Publication Publication Date Title
DE10044420A1 (de) Wirkstoffträger zur anhaltenden Wirkstofffreisetzung und Verfahren zu dessen Herstellung
DE3526335C2 (enExample)
EP0159036B1 (de) Beschichtungsmasse und Verankerungsteil für Implantate
DE3425182C2 (de) Poröses osteogenetisches keramisches Material und Verfahren zu seiner Herstellung sowie seine Verwendung
DE3790291C2 (de) Für Gewebeimplantation brauchbares Material, Verfahren zu dessen Herstellung und Verwendung
EP3332815B1 (de) Strukturierte mineralische knochenersatzformkörper
DE69836200T2 (de) Implantat Material und Verfahren zu seiner Herstellung
DE3531144C2 (enExample)
DE19910188C2 (de) Implantat, Verfahren zu seiner Herstellung und seine Verwendung
DE60113095T2 (de) Oberflächen entmineralisiertes osteoimplantat und verfahren zu seiner herstellung
DE3121182C2 (de) Füllmaterial zum Füllen von Defekten oder Hohlräumen in Knochen
DE69831976T2 (de) Poröser gegenstand aus einer nickel-titan legierung
DE60031991T2 (de) Implantat zur sicherstellung der verabreichung einer bioaktiven substanz im knochen und/oder im gewebe um das implantat
WO2001034216A1 (de) Resorbierbares knochen-implantatmaterial sowie verfahren zur herstellung desselben
DE102004057212B4 (de) Poröse Calciumphosphat-Keramik und Verfahren zu deren Herstellung
DE2717506A1 (de) Keramisches knochenimplantat
DE3445731A1 (de) Werkstoff und seine verwendung
DE2127843A1 (de) Metallische Implantate
EP1121161A1 (de) Zusammensetzung zur implantation in den menschlichen und tierischen körper
EP3319652B1 (de) Verfahren zur herstellung eines bioartifiziellen, primär azellulären konstrukts auf fibrinbasis und dieses konstrukt selbst
DE60118683T2 (de) Poröser Keramikkörper für in vivo oder in vitro Gebrauch
DE69431092T2 (de) Medizinischer Zement, Verfahren zu seiner Herstellung sowie dessen Verwendung
DE102004045410A1 (de) Knochenersatzimplantat für human- und veterinärmedizinische Anwendungen
DE60215895T2 (de) Poröse Calciumphosphat-Keramik für in vivo-Anwendungen
EP0002064B1 (de) Gemisch mit schäumendem und resorbierbarem Effekt zur Herstellung eines Spongiosazementes und Spongiosazement als Implantat bei chirurgischen Eingriffen

Legal Events

Date Code Title Description
8127 New person/name/address of the applicant

Owner name: PENTAX CORP., TOKIO/TOKYO, JP

8110 Request for examination paragraph 44
8125 Change of the main classification

Ipc: A61K 4704

8127 New person/name/address of the applicant

Owner name: HOYA CORP., TOKIO/TOKYO, JP

8130 Withdrawal