DD297063A5 - Verfahren zur behandlung der cardialen sowie der vasculaeren hypertrophie und hyperplasie - Google Patents

Verfahren zur behandlung der cardialen sowie der vasculaeren hypertrophie und hyperplasie Download PDF

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Publication number
DD297063A5
DD297063A5 DD90343366A DD34336690A DD297063A5 DD 297063 A5 DD297063 A5 DD 297063A5 DD 90343366 A DD90343366 A DD 90343366A DD 34336690 A DD34336690 A DD 34336690A DD 297063 A5 DD297063 A5 DD 297063A5
Authority
DD
German Democratic Republic
Prior art keywords
atoms
alkyl
aryl
carbethoxy
carboxylic acid
Prior art date
Application number
DD90343366A
Other languages
German (de)
English (en)
Inventor
Wolfgang Linz
Bernward Schoelkens
Wolfgang Scholz
Gabriele Wiemer
Hansjoerg Urbach
Rainer Henning
Volker Teetz
Original Assignee
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Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=6386970&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DD297063(A5) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by �����@������������������k�� filed Critical �����@������������������k��
Publication of DD297063A5 publication Critical patent/DD297063A5/de

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/55Protease inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/55Protease inhibitors
    • A61K38/556Angiotensin converting enzyme inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/08Vasodilators for multiple indications
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Crystals, And After-Treatments Of Crystals (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Preliminary Treatment Of Fibers (AREA)
  • Crucibles And Fluidized-Bed Furnaces (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Element Separation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DD90343366A 1989-08-11 1990-08-09 Verfahren zur behandlung der cardialen sowie der vasculaeren hypertrophie und hyperplasie DD297063A5 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3926606A DE3926606A1 (de) 1989-08-11 1989-08-11 Verfahren zur behandlung der cardialen sowie der vasculaeren hypertrophie und hyperplasie

Publications (1)

Publication Number Publication Date
DD297063A5 true DD297063A5 (de) 1992-01-02

Family

ID=6386970

Family Applications (1)

Application Number Title Priority Date Filing Date
DD90343366A DD297063A5 (de) 1989-08-11 1990-08-09 Verfahren zur behandlung der cardialen sowie der vasculaeren hypertrophie und hyperplasie

Country Status (22)

Country Link
US (1) US5231083A (pt)
EP (1) EP0417473B1 (pt)
JP (1) JP3452199B2 (pt)
KR (1) KR0185969B1 (pt)
AT (1) ATE94409T1 (pt)
AU (1) AU631914B2 (pt)
CA (1) CA2023089C (pt)
CS (1) CS277644B6 (pt)
DD (1) DD297063A5 (pt)
DE (2) DE3926606A1 (pt)
DK (1) DK0417473T3 (pt)
ES (1) ES2059931T3 (pt)
FI (1) FI903936A0 (pt)
HU (1) HU205008B (pt)
IE (1) IE64604B1 (pt)
IL (1) IL95327A (pt)
NO (1) NO306979B1 (pt)
NZ (1) NZ234836A (pt)
PH (1) PH30831A (pt)
PL (1) PL286442A1 (pt)
PT (1) PT94957B (pt)
ZA (1) ZA906327B (pt)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE157871T1 (de) 1994-05-19 1997-09-15 Mitsubishi Chem Corp Arzneimittel zur therapeutischen und prophylaktischen behandlung von krankheiten, die durch hyperplasie der glatten muskelzellen bedingt sind
SG68529A1 (en) * 1995-05-25 1999-11-16 Univ Singapore The use of des-aspartate-angiotensin i (agr-val-tyr-ile-his-pro-phe-his-leu) as an anti-cardiac hypertrophic agent
SE9903028D0 (sv) * 1999-08-27 1999-08-27 Astra Ab New use
WO2001015674A2 (en) * 1999-08-30 2001-03-08 Aventis Pharma Deutschland Gmbh Use of inhibitors of the renin-angiotensin system in the prevention of cardiovascular events
US6395767B2 (en) * 2000-03-10 2002-05-28 Bristol-Myers Squibb Company Cyclopropyl-fused pyrrolidine-based inhibitors of dipeptidyl peptidase IV and method
EP1817007A2 (en) * 2004-11-05 2007-08-15 King Pharmaceuticals Research and Development Inc. Stabilized individually coated ramipril particles, compositions and methods
US8980924B2 (en) 2010-11-24 2015-03-17 The Trustees Of Columbia University In The City Of New York Non-retinoid RBP4 antagonist for treatment of age-related macular degeneration and stargardt disease
US9333202B2 (en) 2012-05-01 2016-05-10 The Trustees Of Columbia University In The City Of New York Non-retinoid antagonists for treatment of age-related macular degeneration and stargardt disease
US10273243B2 (en) 2013-03-14 2019-04-30 The Trustees Of Columbia University In The City Of New York 4-phenylpiperidines, their preparation and use
US9944644B2 (en) 2013-03-14 2018-04-17 The Trustees Of Columbia University In The City Of New York Octahydropyrrolopyrroles their preparation and use
ES2700541T3 (es) 2013-03-14 2019-02-18 Univ Columbia Octahidrociclopentapirroles, su preparación y uso
US9938291B2 (en) 2013-03-14 2018-04-10 The Trustess Of Columbia University In The City Of New York N-alkyl-2-phenoxyethanamines, their preparation and use
WO2015168286A1 (en) 2014-04-30 2015-11-05 The Trustees Of Columbia University In The City Of New York Substituted 4-phenylpiperidines, their preparaiton and use

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL58849A (en) * 1978-12-11 1983-03-31 Merck & Co Inc Carboxyalkyl dipeptides and derivatives thereof,their preparation and pharmaceutical compositions containing them
US4311705A (en) * 1980-10-06 1982-01-19 E. R. Squibb & Sons, Inc. Carboxyalkanoyl and hydroxycarbamoylalkanoyl derivatives of substituted prolines
US4337201A (en) * 1980-12-04 1982-06-29 E. R. Squibb & Sons, Inc. Phosphinylalkanoyl substituted prolines
US4381297A (en) * 1981-05-04 1983-04-26 E. R. Squibb & Sons, Inc. Substituted carbonyl phosphinyl-alkanoyl compounds
US4602002A (en) * 1983-02-07 1986-07-22 Merck & Co., Inc. N-carboxymethyl substituted lysyl and α-(ε-aminoalkyl) glycyl amino acid antihypertensive agents
US4548941A (en) * 1984-07-30 1985-10-22 Merck & Co., Inc. 1,5-Methano-1H-4-benzazonine dicarboxylates, process for preparing and use as calcium blockers
US4587253A (en) * 1984-07-30 1986-05-06 Merck & Co., Inc. Bridged pyridine compounds useful as calcium channel blockers and analgesics
US4599341A (en) * 1984-10-01 1986-07-08 Merck & Co., Inc. Substituted and bridged pyridines useful as calcium channel blockers
US4656188A (en) * 1985-10-09 1987-04-07 Merck & Co., Inc. Ace inhibitors in macular degeneration
DE3705220A1 (de) * 1987-02-19 1988-09-01 Boehringer Ingelheim Kg Mittel zur behandlung von coronarerkrankungen oder organischem hirnsyndrom
ZA896851B (en) * 1988-09-14 1990-06-27 Hoffmann La Roche Use of ace-inhibitors

Also Published As

Publication number Publication date
PT94957A (pt) 1991-05-22
HUT54504A (en) 1991-03-28
IL95327A0 (en) 1991-06-30
NZ234836A (en) 1997-05-26
HU205008B (en) 1992-03-30
PL286442A1 (en) 1992-03-09
ES2059931T3 (es) 1994-11-16
HU904966D0 (en) 1991-01-28
NO903532L (no) 1991-02-12
PH30831A (en) 1997-10-17
CA2023089C (en) 2003-01-14
KR0185969B1 (ko) 1999-05-01
ATE94409T1 (de) 1993-10-15
AU6092090A (en) 1991-02-14
CS277644B6 (en) 1993-03-17
DE3926606A1 (de) 1991-02-14
CS395890A3 (en) 1992-08-12
DE59002721D1 (de) 1993-10-21
US5231083A (en) 1993-07-27
PT94957B (pt) 1997-05-28
EP0417473B1 (de) 1993-09-15
NO306979B1 (no) 2000-01-24
NO903532D0 (no) 1990-08-10
DK0417473T3 (da) 1993-12-13
IL95327A (en) 1995-10-31
KR910004189A (ko) 1991-03-28
ZA906327B (en) 1991-05-29
EP0417473A1 (de) 1991-03-20
IE64604B1 (en) 1995-08-23
CA2023089A1 (en) 1991-02-12
AU631914B2 (en) 1992-12-10
IE902910A1 (en) 1991-02-27
FI903936A0 (fi) 1990-08-09
JPH0383957A (ja) 1991-04-09
JP3452199B2 (ja) 2003-09-29

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Legal Events

Date Code Title Description
RPI Change in the person, name or address of the patentee (searches according to art. 11 and 12 extension act)
ASS Change of applicant or owner

Owner name: AVENTIS PHARMA DEUTSCHLAND GMBH, FRANKFURT

Effective date: 20000519

IF04 In force in the year 2004

Expiry date: 20100810