DD295358A5 - Verfahren zur racemattrennung von 4-aryl-2-oxo-pyrrolidin-3-carbonsaeure-estern - Google Patents

Verfahren zur racemattrennung von 4-aryl-2-oxo-pyrrolidin-3-carbonsaeure-estern Download PDF

Info

Publication number
DD295358A5
DD295358A5 DD90342261A DD34226189A DD295358A5 DD 295358 A5 DD295358 A5 DD 295358A5 DD 90342261 A DD90342261 A DD 90342261A DD 34226189 A DD34226189 A DD 34226189A DD 295358 A5 DD295358 A5 DD 295358A5
Authority
DD
German Democratic Republic
Prior art keywords
oxo
aryl
carboxylic acid
carbon atoms
pyrrolidine
Prior art date
Application number
DD90342261A
Other languages
German (de)
English (en)
Inventor
Karl Petzoldt
Ralph Schmiechen
Kurt Hamp
Matthias Gottwald
Original Assignee
�����@������������������k��
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by �����@������������������k�� filed Critical �����@������������������k��
Publication of DD295358A5 publication Critical patent/DD295358A5/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/10—Nitrogen as only ring hetero atom
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
    • C12P41/003—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by ester formation, lactone formation or the inverse reactions
    • C12P41/005—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by ester formation, lactone formation or the inverse reactions by esterification of carboxylic acid groups in the enantiomers or the inverse reaction

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Genetics & Genomics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Pyrrole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DD90342261A 1989-06-28 1989-06-28 Verfahren zur racemattrennung von 4-aryl-2-oxo-pyrrolidin-3-carbonsaeure-estern DD295358A5 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3921593A DE3921593A1 (de) 1989-06-28 1989-06-28 Verfahren zur racemattrennung von 4-aryl-2-oxo-pyrrolidin-3-carbonsaeure-ester

Publications (1)

Publication Number Publication Date
DD295358A5 true DD295358A5 (de) 1991-10-31

Family

ID=6384062

Family Applications (1)

Application Number Title Priority Date Filing Date
DD90342261A DD295358A5 (de) 1989-06-28 1989-06-28 Verfahren zur racemattrennung von 4-aryl-2-oxo-pyrrolidin-3-carbonsaeure-estern

Country Status (11)

Country Link
US (1) US5539111A (el)
EP (1) EP0437555B1 (el)
AT (1) ATE127159T1 (el)
CA (1) CA2026862A1 (el)
DD (1) DD295358A5 (el)
DE (2) DE3921593A1 (el)
DK (1) DK0437555T3 (el)
ES (1) ES2076369T3 (el)
GR (1) GR900100368A (el)
IE (1) IE902338A1 (el)
WO (1) WO1991000362A1 (el)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69914458T2 (de) 1998-02-17 2004-10-28 G.D. Searle & Co., Chicago Verfahren zur enzymatischen auflösung von laktamen
DE60233884D1 (de) 2001-10-16 2009-11-12 Memory Pharmaceutical Corp 4(4-alkoxy-3-hydroxyphenyl)-2-pyrrolidon-derivate als pde-4-hemmer zur behandlung von neurologischen syndromen
CA2522631A1 (en) * 2003-04-16 2004-11-04 Memory Pharmaceuticals Corporation 4 - (3,4 - disubstituted phenyl) - pyrrolidin-2-one compounds as phosphodiesterase 4 inhibitors
US7226930B2 (en) * 2003-04-18 2007-06-05 Memory Pharmaceutical Corporation Phosphodiesterase 4 inhibitors
US7148362B2 (en) 2003-09-18 2006-12-12 Hoffmann-La Roche Inc. Process for the preparation of enantiopure pyrrolidin-2-one derivatives
EP1799673A1 (en) 2004-10-15 2007-06-27 Memory Pharmaceuticals Corporation Pyrazole derivatives as phosphodiesterase 4 inhibitors
EP1802615A1 (en) * 2004-10-20 2007-07-04 Memory Pharmaceuticals Corporation Phosphodiesterase 4 inhibitors

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2413935A1 (de) * 1974-03-20 1975-10-16 Schering Ag 4-(polyalkoxy-phenyl)-2-pyrrolidone
DE2834114A1 (de) * 1978-08-01 1980-02-14 Schering Ag Polyalkoxyphenylpyrrolidone iii, verfahren zu ihrer herstellung und ihre verwendung
JPS5931693A (ja) * 1982-08-13 1984-02-20 Kanegafuchi Chem Ind Co Ltd 光学活性オキサゾリジノン誘導体の製造方法
US4732853A (en) * 1984-11-21 1988-03-22 President And Fellows Of Harvard College Method of making chiral epoxy alcohols
DE3680132D1 (de) * 1985-04-01 1991-08-14 Kanegafuchi Chemical Ind Verfahren zur herstellung von optisch aktiver indolin-2-carbonsaeure.
US5180671A (en) * 1986-04-16 1993-01-19 Sumitomo Chemical Company, Limited Method for producing optically active cyclopropane carboxylic acid
US4879421A (en) * 1988-08-15 1989-11-07 General Electric Company Method for preparing optically active binaphthol and spiroibiindanol
DE59205454D1 (de) * 1991-08-22 1996-04-04 Lonza Ag Verfahren zur Herstellung von optisch aktiven 4-Amino-3-hydroxycarbonsäuren

Also Published As

Publication number Publication date
EP0437555B1 (de) 1995-08-30
DE59009580D1 (de) 1995-10-05
DE3921593A1 (de) 1991-01-10
WO1991000362A1 (de) 1991-01-10
ES2076369T3 (es) 1995-11-01
ATE127159T1 (de) 1995-09-15
GR900100368A (el) 1991-11-15
IE902338A1 (en) 1991-01-16
US5539111A (en) 1996-07-23
DK0437555T3 (da) 1995-12-27
CA2026862A1 (en) 1990-12-29
EP0437555A1 (de) 1991-07-24
IE902338L (en) 1990-12-30

Similar Documents

Publication Publication Date Title
DE3051097C2 (el)
DE3687599T2 (de) Optisch aktive pyridobenzoxazinderivate.
DE2227739A1 (de) Neue antibakteriell wirksame substanzen und verfahren zu ihrer herstellung
DE3876039T2 (de) Verfahren zur herstellung von optisch aktiven verbindungen mit pyridin-kernen.
EP0562583B1 (de) Neue Alkylendiammonium-diclavulanat-Derivate, Verfahren zu deren Herstellung sowie deren Verwendung
DE3424440A1 (de) Verfahren zur herstellung optisch aktiver carbonsaeuren und deren ester in form der optischen antipoden
EP0032659A1 (de) Optisch aktive Phenylpropan-Derivate, ihre Herstellung und Verwendung zur Herstellung von Fungiziden
DD295358A5 (de) Verfahren zur racemattrennung von 4-aryl-2-oxo-pyrrolidin-3-carbonsaeure-estern
DE69732772T2 (de) Enzymatisches verfahren zur stereoselektiven herstellung von therapeutischen amiden
EP0492497A2 (de) Verfahren zur Acylierung von Alkoholen mit einem immobilisierten Pseudomonas-Lipase
EP1071807A1 (de) Verfarhen zur enzymatischen enantiomeren-trennung von 3(r)- und 3(s)-hydroxy-1- methyl-4-(2,4, 6-trimethoxyphenyl)-1, 2,3,6- tetrahydro-pyridin bzw. der carbonsäureester
DE69205851T2 (de) Verfahren zur Herstellung von (-)-(2R,3S)-2,3-Epoxy-3-(4-Methoxyphenyl)propionat-methylester.
DE4115697A1 (de) Verfahren zur herstellung von zwischenverbindungen, die bei der synthese von benzothiazepinen verwendbar sind
DE3114242A1 (de) Carbonsaeurederivate, verfahren zu ihrer herstellung und diese derivate enthaltende arzneimittel
AT398579B (de) Enzymatisches verfahren zur trennung racemischer gemische von delta-valerolactonen
EP0511526A1 (de) Verfahren zur enzymatischen Hydrolyse eines Carbonsäurederivates
JPH11228310A (ja) 青枯れ病菌拮抗剤
EP0505514B1 (de) VERFAHREN ZUR HERSTELLUNG VON $g(b)-CARBOLIN-DERIVATEN
DE69006801T2 (de) Optisch aktive Cyclopentenole und Verfahren zu deren Herstellung.
DD272870A5 (de) Verfahren zur racematspaltung von aktiven phosphorhaltigen funktionellen essigsaeurederivate
EP0816343B1 (de) Verfahren zur Herstellung chiraler, nicht racemischer (4-Aryl-2,5-dioxoimidazolidin-1-yl)-essigsäuren
DE69123402T2 (de) Verfahren zur Herstellung optisch aktiver Alpha-Hydroxyalkenderivate
EP0496854B1 (de) Verfahren zur Herstellung von 20-METHYL-5,7-PREGNADIEN-3$g(b),21-DIOL-DERIVATIVEN
EP0019162B1 (de) 12-alpha-Hydroxysteroide und deren Herstellung
DE68904418T2 (de) (+-)- oder (+)-1-(2-n-substituiertes aminoaethyl)-1-methyl-7-methoxy-1,2,3,4-tetrahydronaphthalen und verfahren zu dessen herstellung.

Legal Events

Date Code Title Description
ENJ Ceased due to non-payment of renewal fee