DD294944A5 - Verfahren zur herstellung von 1,2,4-triazolo[4,3-a]pyrazinen - Google Patents

Verfahren zur herstellung von 1,2,4-triazolo[4,3-a]pyrazinen Download PDF

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Publication number
DD294944A5
DD294944A5 DD90341316A DD34131690A DD294944A5 DD 294944 A5 DD294944 A5 DD 294944A5 DD 90341316 A DD90341316 A DD 90341316A DD 34131690 A DD34131690 A DD 34131690A DD 294944 A5 DD294944 A5 DD 294944A5
Authority
DD
German Democratic Republic
Prior art keywords
triazolo
pyrazine
methylamino
fluorobenzyl
group
Prior art date
Application number
DD90341316A
Other languages
German (de)
English (en)
Inventor
James L Kelley
Original Assignee
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Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ��������@��������@����������@���k�� filed Critical ��������@��������@����������@���k��
Publication of DD294944A5 publication Critical patent/DD294944A5/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pain & Pain Management (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DD90341316A 1989-06-06 1990-06-05 Verfahren zur herstellung von 1,2,4-triazolo[4,3-a]pyrazinen DD294944A5 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB898913011A GB8913011D0 (en) 1989-06-06 1989-06-06 Anticonvulsant pyrazines

Publications (1)

Publication Number Publication Date
DD294944A5 true DD294944A5 (de) 1991-10-17

Family

ID=10657983

Family Applications (1)

Application Number Title Priority Date Filing Date
DD90341316A DD294944A5 (de) 1989-06-06 1990-06-05 Verfahren zur herstellung von 1,2,4-triazolo[4,3-a]pyrazinen

Country Status (11)

Country Link
US (1) US5095018A (fr)
EP (1) EP0402096B1 (fr)
JP (1) JP3027762B2 (fr)
AT (1) ATE141604T1 (fr)
AU (1) AU628581B2 (fr)
CA (1) CA2018308C (fr)
DD (1) DD294944A5 (fr)
DE (1) DE69028147T2 (fr)
ES (1) ES2091796T3 (fr)
GB (1) GB8913011D0 (fr)
NZ (1) NZ233928A (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3173792B2 (ja) * 1993-02-22 2001-06-04 メルク エンド カンパニー インコーポレーテッド フィブリノーゲンレセプターアンタゴニスト
US5821241A (en) * 1994-02-22 1998-10-13 Merck & Co., Inc. Fibrinogen receptor antagonists
US5981584A (en) * 1997-02-06 1999-11-09 Merck & Co., Inc. Fibrinogen receptor antagonist prodrugs
AU9651198A (en) * 1997-11-11 1999-05-31 Ono Pharmaceutical Co. Ltd. Fused pyrazine compounds
WO2011082267A2 (fr) * 2009-12-30 2011-07-07 Arqule, Inc. Composés triazolo-pyrazine substitués

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1146770A (en) * 1967-02-03 1969-03-26 Ici Ltd S-triazolo[4,3-a]pyrazine derivatives
JPS5129766B2 (fr) * 1971-10-04 1976-08-27
US4056632A (en) * 1975-07-21 1977-11-01 Burroughs Wellcome Co. 2-Hydroxymethyl-2'-aminomethyl-diphenylsulfides and method of use
US3997540A (en) * 1975-07-21 1976-12-14 Burroughs Wellcome Co. O [(O-piperazinocarbonyl-phenyl)-thio]-benzoates
US4438266A (en) * 1982-05-17 1984-03-20 Merck & Co., Inc. Triazolopyrazinamines useful as adjuncts to radiation therapy
GB8408615D0 (en) * 1984-04-04 1984-05-16 Wellcome Found Heterocyclic compounds
MC1673A1 (fr) * 1984-06-27 1986-06-03 Wellcome Found Derives aryliques de composes imidazoliques,leur preparation et leur emploi pour la preparation des medicaments

Also Published As

Publication number Publication date
DE69028147D1 (de) 1996-09-26
EP0402096A3 (fr) 1991-09-18
DE69028147T2 (de) 1997-01-02
US5095018A (en) 1992-03-10
JP3027762B2 (ja) 2000-04-04
EP0402096B1 (fr) 1996-08-21
GB8913011D0 (en) 1989-07-26
EP0402096A2 (fr) 1990-12-12
AU628581B2 (en) 1992-09-17
NZ233928A (en) 1992-10-28
JPH0320276A (ja) 1991-01-29
CA2018308C (fr) 2000-08-01
AU5684290A (en) 1990-12-13
ES2091796T3 (es) 1996-11-16
ATE141604T1 (de) 1996-09-15
CA2018308A1 (fr) 1990-12-06

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Legal Events

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ENJ Ceased due to non-payment of renewal fee