DD220310A5 - Verfahren zur herstellung von triazol (2,3-c)(1,3) benzodiazepinen) - Google Patents

Verfahren zur herstellung von triazol (2,3-c)(1,3) benzodiazepinen) Download PDF

Info

Publication number
DD220310A5
DD220310A5 DD84263805A DD26380584A DD220310A5 DD 220310 A5 DD220310 A5 DD 220310A5 DD 84263805 A DD84263805 A DD 84263805A DD 26380584 A DD26380584 A DD 26380584A DD 220310 A5 DD220310 A5 DD 220310A5
Authority
DD
German Democratic Republic
Prior art keywords
alkyl
hydrogen
formula
lower alkyl
hydroxy
Prior art date
Application number
DD84263805A
Other languages
German (de)
English (en)
Inventor
Isidoros Vlattas
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of DD220310A5 publication Critical patent/DD220310A5/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D249/00Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/081,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D231/00Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D249/00Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/081,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C07D249/101,2,4-Triazoles; Hydrogenated 1,2,4-triazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D249/00Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/081,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C07D249/101,2,4-Triazoles; Hydrogenated 1,2,4-triazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D249/12Oxygen or sulfur atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Psychiatry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Steroid Compounds (AREA)
DD84263805A 1983-06-06 1984-06-05 Verfahren zur herstellung von triazol (2,3-c)(1,3) benzodiazepinen) DD220310A5 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US50132883A 1983-06-06 1983-06-06

Publications (1)

Publication Number Publication Date
DD220310A5 true DD220310A5 (de) 1985-03-27

Family

ID=23993078

Family Applications (1)

Application Number Title Priority Date Filing Date
DD84263805A DD220310A5 (de) 1983-06-06 1984-06-05 Verfahren zur herstellung von triazol (2,3-c)(1,3) benzodiazepinen)

Country Status (17)

Country Link
EP (1) EP0129509B1 (pt)
JP (1) JPS606689A (pt)
AT (1) ATE45740T1 (pt)
AU (1) AU574075B2 (pt)
CA (1) CA1215044A (pt)
DD (1) DD220310A5 (pt)
DE (1) DE3479499D1 (pt)
DK (1) DK276484A (pt)
ES (1) ES8506713A1 (pt)
FI (1) FI78098C (pt)
GR (1) GR82058B (pt)
HU (1) HU190930B (pt)
IL (1) IL72015A (pt)
NO (1) NO162070C (pt)
NZ (1) NZ208373A (pt)
PT (1) PT78687A (pt)
ZA (1) ZA844186B (pt)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL84093A (en) * 1986-10-09 1992-09-06 Ciba Geigy Ag Aralkyl-4h-1,2,4-triazole derivatives,their preparation and pharmaceutical compositions containing them
DE19824673A1 (de) * 1998-05-26 1999-12-02 Schering Ag Neue 2,3-Benzodiazepinderivate, deren Herstellung und Verwendung als Arzneimittel

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3539573A (en) * 1967-03-22 1970-11-10 Jean Schmutz 11-basic substituted dibenzodiazepines and dibenzothiazepines
US4076823A (en) * 1977-08-18 1978-02-28 E. R. Squibb & Sons, Inc. Triazolo-2,4-benzodiazepines
US4192803A (en) * 1978-09-15 1980-03-11 American Cyanamid Company 5H-Pyrrolo[2,1-c][1,4]benzodiazepine derivatives
FI824170L (fi) * 1981-12-07 1983-06-08 Ciba Geigy Ag Imidazobensodiazepiner, foerfarande foer deras framstaellning, dessa foereningar innehaollande farmaceutiska preparat och deras anvaendning

Also Published As

Publication number Publication date
EP0129509A3 (en) 1985-09-11
NO842254L (no) 1984-12-07
ATE45740T1 (de) 1989-09-15
ES533135A0 (es) 1985-08-01
JPH0354669B2 (pt) 1991-08-20
NO162070C (no) 1989-11-01
EP0129509A2 (de) 1984-12-27
FI78098B (fi) 1989-02-28
GR82058B (pt) 1984-12-13
AU574075B2 (en) 1988-06-30
DK276484A (da) 1984-12-07
CA1215044A (en) 1986-12-09
HUT34488A (en) 1985-03-28
NO162070B (no) 1989-07-24
IL72015A (en) 1987-12-31
IL72015A0 (en) 1984-10-31
HU190930B (en) 1986-12-28
JPS606689A (ja) 1985-01-14
PT78687A (en) 1984-07-01
FI842228A0 (fi) 1984-06-04
EP0129509B1 (de) 1989-08-23
AU2910684A (en) 1984-12-13
DE3479499D1 (en) 1989-09-28
DK276484D0 (da) 1984-06-04
ZA844186B (en) 1985-02-27
FI78098C (fi) 1989-06-12
ES8506713A1 (es) 1985-08-01
NZ208373A (en) 1987-02-20
FI842228A (fi) 1984-12-07

Similar Documents

Publication Publication Date Title
DE69407176T2 (de) Antipsychotische benzimidazolderivate
DE2940483C2 (pt)
DE3502508C2 (pt)
DE3423898A1 (de) Piperazinyl-alkyl-1,2,4-triazol-3-on-derivate, verfahren zu deren herstellung und diese verbindungen enthaltende pharmazeutische mittel
CH649539A5 (de) Antidepressiv wirksame piperazinylalkyl-1,2,4-triazol-3-one.
DE1795062A1 (de) 1H-Imidazo[4,5-b]pyrazin-2-one und Verfahren zu ihrer Herstellung
DD207716A5 (de) Verfahren zur herstellung von 1,2,4-triazinen und von pyrazinen
DD213920A5 (de) Verfahren zur herstellung von dihydropyridinen
DE2628189A1 (de) 3-phenylindoline, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE60111568T2 (de) Tetrahydro-(benzo- oder thieno-)azepin-pyrazin und triazinderivative als mglur 1 antagonisten
DE3343922A1 (de) Gewisse substituierte pyrazolochinoline, verfahren zu ihrer herstellung, pharmazeutische praeparate enthaltend diese verbindungen und ihre therapeutische anwendung
DE10036818A1 (de) Neue N-Triazolylmethyl-Piperazinderivate als Neurokininrezeptor-Antagonisten
DE1695132A1 (de) Verfahren zur Herstellung von heterocyclischen Verbindungen
DE2804519C2 (pt)
EP0445073A1 (de) Benzofurane
DD282457A5 (de) Verfahren zur herstellung neuer heterocyclischer derivate
DD220310A5 (de) Verfahren zur herstellung von triazol (2,3-c)(1,3) benzodiazepinen)
EP0042354B1 (de) Imidazobenzothiadiazepine, Verfahren zu ihrer Herstellung sowie pharmazeutische Präparate die diese Verbindungen enthalten
EP0233483A2 (de) Pyrrolo[1,2-a][4,1]benzoxazepine, Verfahren zur ihrer Herstellung, pharmazeutische Präparate enthaltend diese Verbindungen, sowie therapeutische Verwendung
DE60002395T2 (de) Metalloproteaseinhibitoren, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Zubereitungen
CH644380A5 (de) Benzodiazepinderivate.
EP0081461A2 (de) Imidazobenzodiazepine, Verfahren zu ihrer Herstellung, pharmazeutische Präparate enthaltend diese Verbindungen, sowie ihre therapeutische Verwendung
DE3404193A1 (de) 5-fluor-pyrimidin-2-yl-piperazin-verbindung, verfahren zu ihrer herstellung und pharmazeutische mittel
DE69324794T2 (de) Phenyl imidazolinon-derivate, verfahren zu ihrer herstellung und ihre verwendung als 5-ht3-rezeptor-antagonisten
DE1695211A1 (de) Verfahren zur Herstellung von Benzodiazepin-Derivaten

Legal Events

Date Code Title Description
ENJ Ceased due to non-payment of renewal fee