DD210258A5 - Verfahren zur herstellung von a-21978c-cyclopeptidderivaten - Google Patents

Verfahren zur herstellung von a-21978c-cyclopeptidderivaten Download PDF

Info

Publication number
DD210258A5
DD210258A5 DD83251130A DD25113083A DD210258A5 DD 210258 A5 DD210258 A5 DD 210258A5 DD 83251130 A DD83251130 A DD 83251130A DD 25113083 A DD25113083 A DD 25113083A DD 210258 A5 DD210258 A5 DD 210258A5
Authority
DD
German Democratic Republic
Prior art keywords
formula
amino
group
alkyl
aminoacyl
Prior art date
Application number
DD83251130A
Other languages
German (de)
English (en)
Inventor
Manuel Debono
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of DD210258A5 publication Critical patent/DD210258A5/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/045—Actinoplanes
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/19—Antibiotic
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/27—Cyclic peptide or cyclic protein

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DD83251130A 1982-05-21 1983-05-20 Verfahren zur herstellung von a-21978c-cyclopeptidderivaten DD210258A5 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/380,499 US4396543A (en) 1982-05-21 1982-05-21 Derivatives of A-21978C cyclic peptides

Publications (1)

Publication Number Publication Date
DD210258A5 true DD210258A5 (de) 1984-06-06

Family

ID=23501405

Family Applications (1)

Application Number Title Priority Date Filing Date
DD83251130A DD210258A5 (de) 1982-05-21 1983-05-20 Verfahren zur herstellung von a-21978c-cyclopeptidderivaten

Country Status (14)

Country Link
US (1) US4396543A (pm)
KR (1) KR860002193B1 (pm)
AT (1) AT381104B (pm)
CA (1) CA1216580A (pm)
DD (1) DD210258A5 (pm)
DK (1) DK221283A (pm)
ES (1) ES522559A0 (pm)
FI (1) FI831747L (pm)
GR (1) GR78850B (pm)
HU (1) HU193528B (pm)
PH (1) PH23417A (pm)
PL (1) PL242097A1 (pm)
PT (1) PT76702B (pm)
RO (1) RO86723B (pm)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4977083A (en) * 1988-04-11 1990-12-11 Eli Lilly And Company Processes for preparing A54145 compounds
ES2379107T3 (es) * 1996-03-08 2012-04-20 Astellas Pharma Inc. Procedimiento para la desacilación de lipopéptidos cíclicos
IL150223A0 (en) * 1999-12-15 2002-12-01 Cubist Pharm Inc Lipopeptides and pharmaceutical compositions containing the same
MXPA02006030A (es) * 1999-12-15 2004-08-23 Cubist Pharm Inc Lipopeptidos como agentes antibacterianos.
US6794490B2 (en) * 1999-12-15 2004-09-21 Cubist Pharmaceuticals, Inc. Lipopeptides as antibacterial agents
ATE459368T1 (de) * 2001-04-25 2010-03-15 Wyeth Corp Glycopeptid-antibiotika
CN102325787B (zh) * 2008-12-22 2014-05-28 丘比斯特药物股份有限公司 治疗革兰氏阳性感染的新的抗菌剂
US11174288B2 (en) 2016-12-06 2021-11-16 Northeastern University Heparin-binding cationic peptide self-assembling peptide amphiphiles useful against drug-resistant bacteria

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3150059A (en) * 1962-12-26 1964-09-22 Lilly Co Eli Penicillin deacylation via actinoplanaceae fermentation
US4050989A (en) * 1974-12-05 1977-09-27 Eisai Co., Ltd. Process of preparing desacyl-pepsidine with bacillus pumilus
US4208403A (en) * 1978-10-16 1980-06-17 Eli Lilly And Company A-21978 Antibiotics and process for their production
US4293488A (en) * 1979-12-13 1981-10-06 Eli Lilly And Company Derivatives of A-30912B nucleus
US4293482A (en) * 1979-12-13 1981-10-06 Eli Lilly And Company A-30912A Nucleus
US4293487A (en) * 1979-12-13 1981-10-06 Eli Lilly And Company Derivatives of A-30912D nucleus
US4293485A (en) * 1979-12-13 1981-10-06 Eli Lilly And Company Derivatives of S31794/F-1 nucleus
US4293483A (en) * 1979-12-13 1981-10-06 Eli Lilly And Company Derivatives of A-30912A nucleus
US4293491A (en) * 1979-12-13 1981-10-06 Eli Lilly And Company Derivatives of A-30912H nucleus

Also Published As

Publication number Publication date
GR78850B (pm) 1984-10-02
US4396543A (en) 1983-08-02
PT76702A (en) 1983-06-01
PL242097A1 (en) 1984-07-02
PH23417A (en) 1989-08-07
DK221283A (da) 1983-11-22
FI831747A0 (fi) 1983-05-18
ES8407011A1 (es) 1984-09-01
RO86723A (ro) 1985-04-17
PT76702B (en) 1986-03-27
FI831747A7 (fi) 1983-11-22
AT381104B (de) 1986-08-25
CA1216580A (en) 1987-01-13
RO86723B (ro) 1985-05-01
DK221283D0 (da) 1983-05-18
FI831747L (fi) 1983-11-22
ATA178483A (de) 1986-01-15
HU193528B (en) 1987-10-28
KR840005077A (ko) 1984-11-03
ES522559A0 (es) 1984-09-01
KR860002193B1 (ko) 1986-12-30

Similar Documents

Publication Publication Date Title
DE69122432T2 (de) Zyklisches Polypeptid mit antibiotischer Aktivität, dessen Herstellung und Reinkultur eines Coelomycetes Stammes
DE3782720T2 (de) Glykopeptid-antibiotika.
DE68905119T2 (de) Methode zur kontrolle von pneumocystis carinii.
EP0629636A1 (de) Lipopeptide aus Actinoplanes sp. mit pharmakologischer Wirkung, Verfahren zu ihrer Herstellung und Verwendung derselben
DE3780644T2 (de) Glykopeptid-antibiotika.
DD146618A5 (de) Verfahren zur herstellung des antibiotikums
DD209810A5 (de) Verfahren zur herstellung von a-21978c-cyclopeptidderivaten
EP0362520B1 (de) Ein neues Antibiotikum, Mersacidin, ein Verfahren zur seiner Herstellung und seine Verwendung als Arzneimittel
DE68914021T2 (de) Antibiotika TAN-1057.
EP0916680B1 (de) Lantibiotikum verwandt mit Actagardine, Verfahren zur Herstellung und Verwendung desselben
DE68925806T2 (de) C63-Amidderivate von 34-de(acetylglucosaminyl)-34-deoxy-teicoplaninen
DD210258A5 (de) Verfahren zur herstellung von a-21978c-cyclopeptidderivaten
DE69108972T2 (de) Antibiotika GE 2270 Faktoren B1, B2, C1, D1, D2, E und T.
DE68920898T2 (de) Aglykone von A/16686-Antibiotika.
NZ204249A (en) A-21978c cyclic peptide derivatives and antimicrobial compositions
DE3885394T2 (de) Teicoplaninähnliche Derivate.
EP0521408B1 (de) Balhimycin-abgeleitete glykopeptidische Antibiotika
DE3586344T2 (de) Esterderivate vom antibiotikum l 17046.
DE68925540T2 (de) Peptid-Antibiotika
DE69224497T2 (de) Faktor C2a des Antibiotikums CE 2270
DE60110908T2 (de) Antibiotische tripropeptine und verfahren ihrer herstellung
EP0005956A1 (en) A-38533 antibiotics, their preparation, formulations containing them, and micro-organism employed in their production
DE69709802T2 (de) Amythiamicin Amid-Derivate
DE69317058T2 (de) Die antibiotika ge 37468 a, b und c
DE3887292T2 (de) Antibiotische Verbindungen, genannt A/16686-Faktoren A'1,A'2 und A'3.