DD202161A5 - Verfahren zur herstellung von in stellung 6 substituierten hexahydroindazoloisochinolinen oder hexahydroisoindoloisochinolinen - Google Patents

Verfahren zur herstellung von in stellung 6 substituierten hexahydroindazoloisochinolinen oder hexahydroisoindoloisochinolinen Download PDF

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Publication number
DD202161A5
DD202161A5 DD82238403A DD23840382A DD202161A5 DD 202161 A5 DD202161 A5 DD 202161A5 DD 82238403 A DD82238403 A DD 82238403A DD 23840382 A DD23840382 A DD 23840382A DD 202161 A5 DD202161 A5 DD 202161A5
Authority
DD
German Democratic Republic
Prior art keywords
dimethoxy
hexahydroindazolo
methyl
propyl
general formula
Prior art date
Application number
DD82238403A
Other languages
German (de)
English (en)
Inventor
Edmund C Kornfeld
Nicholas J Bach
Robert D Titus
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of DD202161A5 publication Critical patent/DD202161A5/de

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D221/00Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/04Ortho- or peri-condensed ring systems
    • C07D221/06Ring systems of three rings
    • C07D221/14Aza-phenalenes, e.g. 1,8-naphthalimide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/08Antiepileptics; Anticonvulsants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D217/00Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
    • C07D217/14Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D217/00Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
    • C07D217/14Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals
    • C07D217/16Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals substituted by oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/06Peri-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Psychology (AREA)
  • Pain & Pain Management (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Indole Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Crystals, And After-Treatments Of Crystals (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DD82238403A 1981-03-24 1982-03-24 Verfahren zur herstellung von in stellung 6 substituierten hexahydroindazoloisochinolinen oder hexahydroisoindoloisochinolinen DD202161A5 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US24704781A 1981-03-24 1981-03-24

Publications (1)

Publication Number Publication Date
DD202161A5 true DD202161A5 (de) 1983-08-31

Family

ID=22933334

Family Applications (1)

Application Number Title Priority Date Filing Date
DD82238403A DD202161A5 (de) 1981-03-24 1982-03-24 Verfahren zur herstellung von in stellung 6 substituierten hexahydroindazoloisochinolinen oder hexahydroisoindoloisochinolinen

Country Status (21)

Country Link
EP (2) EP0061341B1 (xx)
JP (1) JPS57171993A (xx)
KR (1) KR830009098A (xx)
AT (2) ATE33641T1 (xx)
AU (1) AU8181482A (xx)
CA (3) CA1182457A (xx)
DD (1) DD202161A5 (xx)
DE (2) DE3278359D1 (xx)
DK (1) DK130282A (xx)
ES (2) ES8305762A1 (xx)
FI (1) FI820938L (xx)
GB (2) GB2095255B (xx)
GR (1) GR75926B (xx)
HU (1) HU189572B (xx)
IL (3) IL65269A0 (xx)
PH (2) PH18370A (xx)
PL (2) PL235582A1 (xx)
PT (1) PT74612B (xx)
RO (2) RO86517B (xx)
SU (1) SU1189349A3 (xx)
ZA (1) ZA821805B (xx)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3624607A1 (de) * 1986-07-21 1988-01-28 Boehringer Ingelheim Kg Neue tetrahydrobenzothiazolo-chinoline ihre herstellung und verwendung
CN107434781A (zh) * 2016-05-27 2017-12-05 河南工业大学 一种1-烯基-异喹啉衍生物的制备方法及其应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4198415A (en) * 1979-01-22 1980-04-15 Eli Lilly And Company Prolactin inhibiting octahydro pyrazolo[3,4-g]quinolines
DK268979A (da) * 1979-01-22 1980-07-23 Lilly Co Eli Fremgangsmaade til fremstilling af octahydro-2h-pyrrolo (3,4-g)quinoliner
US4201862A (en) * 1979-03-16 1980-05-06 Eli Lilly And Company 2-Azaergolines and 2-aza-8(or 9)-ergolenes

Also Published As

Publication number Publication date
ATE33641T1 (de) 1988-05-15
ES519056A0 (es) 1984-03-16
FI820938L (fi) 1982-09-25
SU1189349A3 (ru) 1985-10-30
EP0151319B1 (en) 1988-04-20
CA1182457A (en) 1985-02-12
EP0061341A2 (en) 1982-09-29
IL74836A0 (en) 1985-07-31
IL74837A0 (en) 1985-07-31
GB2095255A (en) 1982-09-29
EP0151319A1 (en) 1985-08-14
RO82502B (ro) 1983-08-30
ES510695A0 (es) 1983-04-16
AU8181482A (en) 1982-09-30
DE3270838D1 (en) 1986-06-05
EP0061341B1 (en) 1986-04-30
GB8425095D0 (en) 1984-11-07
DE3278359D1 (en) 1988-05-26
EP0061341A3 (en) 1982-12-08
RO86517A (ro) 1985-03-15
CA1187883A (en) 1985-05-28
GB2095255B (en) 1985-07-17
ES8403459A1 (es) 1984-03-16
ZA821805B (en) 1983-10-26
JPS57171993A (en) 1982-10-22
IL65269A0 (en) 1982-05-31
DK130282A (da) 1982-09-25
RO82502A (ro) 1983-09-26
PL235582A1 (en) 1983-08-15
KR830009098A (ko) 1983-12-17
ES8305762A1 (es) 1983-04-16
PH18370A (en) 1985-06-13
ATE19517T1 (de) 1986-05-15
CA1187884A (en) 1985-05-28
HU189572B (en) 1986-07-28
PT74612B (en) 1984-11-27
PH18719A (en) 1985-09-11
RO86517B (ro) 1985-03-30
PT74612A (en) 1982-04-01
GR75926B (xx) 1984-08-02
PL240285A1 (en) 1983-09-12

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