RO86517B - Procedeu pentru prepararea hexahidroizoindolizochinolinelor 6-substituite - Google Patents
Procedeu pentru prepararea hexahidroizoindolizochinolinelor 6-substituiteInfo
- Publication number
- RO86517B RO86517B RO111501A RO11150182A RO86517B RO 86517 B RO86517 B RO 86517B RO 111501 A RO111501 A RO 111501A RO 11150182 A RO11150182 A RO 11150182A RO 86517 B RO86517 B RO 86517B
- Authority
- RO
- Romania
- Prior art keywords
- alkoxy
- substituted
- hexahydroisoindolisoquinoleine
- preparing
- chem
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/04—Ortho- or peri-condensed ring systems
- C07D221/06—Ring systems of three rings
- C07D221/14—Aza-phenalenes, e.g. 1,8-naphthalimide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
- C07D217/14—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
- C07D217/14—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals
- C07D217/16—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals substituted by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/06—Peri-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Neurology (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Neurosurgery (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biomedical Technology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pain & Pain Management (AREA)
- Psychology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Indole Compounds (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Crystals, And After-Treatments Of Crystals (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Abstract
Inventia se refera la o celuiloza microcristalina caracterizata prin aceea ca, prezinta la un grad de polimerizare între 324 si 420 un indice de cristalitate de 77,5...79,0 un indice de filtrare de 1,02.10 la minus 3...1,525.10 la minus 3, suprafata specifica si densitatea în gramada fiind de 10..18,4 m patrat/g, respectiv 0,135...0,160 g/cm cub, suma fractiilor sub 72,36 si 77,80. Procedeul de obtinere a celulozei conform revendicarii 1, prin hidroliza cu o solutie concentrata de H2SO4 a celulozei de fag, la un hidromodul de 1:20, urmata de filtrare, spalare cu apa demineralizata la un pH neutru al produsului hidrolizat, uscare si macinare, se caracterizeaza prin aceea ca, se utilizeaza H2SO4 de concentratie 54%, hidroliza avînd loc la temperaturi de 55 degree C...65 degree C, timp de 4 sau 5h.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US24704781A | 1981-03-24 | 1981-03-24 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| RO86517A RO86517A (ro) | 1985-03-15 |
| RO86517B true RO86517B (ro) | 1985-03-30 |
Family
ID=22933334
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RO82106957A RO82502A (ro) | 1981-03-24 | 1982-03-18 | Procedeu pentru prepararea hexahidroindazol-izochinolinelor-6-substitprocedeu pentru prepararea hexahidroindazol-izochinolinelor-6-substituite |
| RO111501A RO86517B (ro) | 1981-03-24 | 1982-03-18 | Procedeu pentru prepararea hexahidroizoindolizochinolinelor 6-substituite |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RO82106957A RO82502A (ro) | 1981-03-24 | 1982-03-18 | Procedeu pentru prepararea hexahidroindazol-izochinolinelor-6-substitprocedeu pentru prepararea hexahidroindazol-izochinolinelor-6-substituite |
Country Status (21)
| Country | Link |
|---|---|
| EP (2) | EP0151319B1 (ro) |
| JP (1) | JPS57171993A (ro) |
| KR (1) | KR830009098A (ro) |
| AT (2) | ATE19517T1 (ro) |
| AU (1) | AU8181482A (ro) |
| CA (3) | CA1182457A (ro) |
| DD (1) | DD202161A5 (ro) |
| DE (2) | DE3278359D1 (ro) |
| DK (1) | DK130282A (ro) |
| ES (2) | ES510695A0 (ro) |
| FI (1) | FI820938L (ro) |
| GB (2) | GB2095255B (ro) |
| GR (1) | GR75926B (ro) |
| HU (1) | HU189572B (ro) |
| IL (3) | IL65269A0 (ro) |
| PH (2) | PH18370A (ro) |
| PL (2) | PL235582A1 (ro) |
| PT (1) | PT74612B (ro) |
| RO (2) | RO82502A (ro) |
| SU (1) | SU1189349A3 (ro) |
| ZA (1) | ZA821805B (ro) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3624607A1 (de) * | 1986-07-21 | 1988-01-28 | Boehringer Ingelheim Kg | Neue tetrahydrobenzothiazolo-chinoline ihre herstellung und verwendung |
| CN107434781A (zh) * | 2016-05-27 | 2017-12-05 | 河南工业大学 | 一种1-烯基-异喹啉衍生物的制备方法及其应用 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ190834A (en) * | 1979-01-22 | 1984-07-06 | Lilly Co Eli | Trans-dl-5-(alkyl or allyl)-4,4a,5,6,7,8,8a,9-octahydro-21 + pyrrolo(3,4-g)quinolines, |
| US4198415A (en) * | 1979-01-22 | 1980-04-15 | Eli Lilly And Company | Prolactin inhibiting octahydro pyrazolo[3,4-g]quinolines |
| US4201862A (en) * | 1979-03-16 | 1980-05-06 | Eli Lilly And Company | 2-Azaergolines and 2-aza-8(or 9)-ergolenes |
-
1982
- 1982-03-16 IL IL65269A patent/IL65269A0/xx unknown
- 1982-03-17 CA CA000398593A patent/CA1182457A/en not_active Expired
- 1982-03-17 ZA ZA821805A patent/ZA821805B/xx unknown
- 1982-03-18 FI FI820938A patent/FI820938L/fi not_active Application Discontinuation
- 1982-03-18 RO RO82106957A patent/RO82502A/ro unknown
- 1982-03-18 RO RO111501A patent/RO86517B/ro unknown
- 1982-03-19 PH PH27025A patent/PH18370A/en unknown
- 1982-03-19 PT PT74612A patent/PT74612B/pt unknown
- 1982-03-23 DE DE8484201377T patent/DE3278359D1/de not_active Expired
- 1982-03-23 GR GR67692A patent/GR75926B/el unknown
- 1982-03-23 GB GB8208503A patent/GB2095255B/en not_active Expired
- 1982-03-23 DK DK130282A patent/DK130282A/da not_active Application Discontinuation
- 1982-03-23 HU HU82878A patent/HU189572B/hu unknown
- 1982-03-23 PL PL23558282A patent/PL235582A1/xx unknown
- 1982-03-23 ES ES510695A patent/ES510695A0/es active Granted
- 1982-03-23 AT AT82301483T patent/ATE19517T1/de not_active IP Right Cessation
- 1982-03-23 EP EP84201377A patent/EP0151319B1/en not_active Expired
- 1982-03-23 EP EP82301483A patent/EP0061341B1/en not_active Expired
- 1982-03-23 AT AT84201377T patent/ATE33641T1/de not_active IP Right Cessation
- 1982-03-23 PL PL24028582A patent/PL240285A1/xx unknown
- 1982-03-23 DE DE8282301483T patent/DE3270838D1/de not_active Expired
- 1982-03-23 SU SU823408197A patent/SU1189349A3/ru active
- 1982-03-23 AU AU81814/82A patent/AU8181482A/en not_active Abandoned
- 1982-03-24 DD DD82238403A patent/DD202161A5/de unknown
- 1982-03-24 JP JP57048077A patent/JPS57171993A/ja active Pending
- 1982-03-24 KR KR1019820001256A patent/KR830009098A/ko unknown
-
1983
- 1983-01-17 ES ES519056A patent/ES8403459A1/es not_active Expired
- 1983-06-30 PH PH29152A patent/PH18719A/en unknown
-
1984
- 1984-06-27 CA CA000457636A patent/CA1187884A/en not_active Expired
- 1984-06-27 CA CA000457635A patent/CA1187883A/en not_active Expired
- 1984-10-04 GB GB848425095A patent/GB8425095D0/en active Pending
-
1985
- 1985-04-08 IL IL74836A patent/IL74836A0/xx unknown
- 1985-04-08 IL IL74837A patent/IL74837A0/xx unknown
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