DD134227A5 - Verfahren zur herstellung von dimeren indoldihydroindoldionen - Google Patents

Verfahren zur herstellung von dimeren indoldihydroindoldionen

Info

Publication number
DD134227A5
DD134227A5 DD77202423A DD20242377A DD134227A5 DD 134227 A5 DD134227 A5 DD 134227A5 DD 77202423 A DD77202423 A DD 77202423A DD 20242377 A DD20242377 A DD 20242377A DD 134227 A5 DD134227 A5 DD 134227A5
Authority
DD
German Democratic Republic
Prior art keywords
indoldiydroindoledoes
dimeric
production
dimeric indoldiydroindoledoes
Prior art date
Application number
DD77202423A
Other languages
German (de)
English (en)
Inventor
Jean C Miller
Gerald E Gutowski
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of DD134227A5 publication Critical patent/DD134227A5/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D519/00Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • C07D519/04Dimeric indole alkaloids, e.g. vincaleucoblastine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Indole Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
DD77202423A 1976-12-06 1977-12-06 Verfahren zur herstellung von dimeren indoldihydroindoldionen DD134227A5 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/747,575 US4096148A (en) 1976-12-06 1976-12-06 Oxazolidinedione derivatives of Vinca alkaloids

Publications (1)

Publication Number Publication Date
DD134227A5 true DD134227A5 (de) 1979-02-14

Family

ID=25005690

Family Applications (2)

Application Number Title Priority Date Filing Date
DD77202423A DD134227A5 (de) 1976-12-06 1977-12-06 Verfahren zur herstellung von dimeren indoldihydroindoldionen
DD77202424A DD134228A5 (de) 1976-12-06 1977-12-06 Verfahren zur herstellung von spirooxazolidindionen

Family Applications After (1)

Application Number Title Priority Date Filing Date
DD77202424A DD134228A5 (de) 1976-12-06 1977-12-06 Verfahren zur herstellung von spirooxazolidindionen

Country Status (31)

Country Link
US (1) US4096148A (hu)
JP (1) JPS5371100A (hu)
AR (1) AR218467A1 (hu)
AT (2) AT353987B (hu)
AU (1) AU513936B2 (hu)
BE (1) BE861417A (hu)
BG (2) BG33437A3 (hu)
CA (2) CA1103664A (hu)
CH (2) CH634076A5 (hu)
CS (2) CS195343B2 (hu)
DD (2) DD134227A5 (hu)
DE (1) DE2753791A1 (hu)
DK (2) DK144916C (hu)
ES (2) ES464765A1 (hu)
FR (1) FR2372839A1 (hu)
GB (1) GB1590649A (hu)
GR (2) GR67244B (hu)
HK (1) HK57281A (hu)
HU (2) HU180724B (hu)
IE (1) IE46105B1 (hu)
IL (1) IL53506A (hu)
MX (1) MX4326E (hu)
MY (1) MY8200176A (hu)
NL (1) NL7713336A (hu)
NZ (1) NZ185818A (hu)
PL (2) PL110671B1 (hu)
PT (2) PT67343B (hu)
RO (2) RO74137A (hu)
SE (2) SE436036B (hu)
SU (2) SU865127A3 (hu)
ZA (1) ZA777237B (hu)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU181874B (en) * 1977-08-08 1983-11-28 Lilly Co Eli Process for preparing amides of deacetyl-leurosine and deacetyl-leuroformine
US4357334A (en) * 1980-03-20 1982-11-02 Eli Lilly And Company Use of VLB 3-(2-chloroethyl) carboxamide in treating neoplasms
US4362664A (en) * 1980-12-29 1982-12-07 Eli Lilly And Company Vinblastine oxazolidinedione disulfides and related compounds
ATE64396T1 (de) * 1983-04-29 1991-06-15 Omnichem Sa Konjugierte vinblastin-verbindungen und ihre derivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zusammensetzungen.
HUT76925A (hu) * 1995-04-04 1998-01-28 MTA Enzimológiai Intézet Bisz-indol-származékok, eljárás előállításukra és az azokat tartalmazó gyógyszerkészítmények
EP1229934B1 (en) 1999-10-01 2014-03-05 Immunogen, Inc. Compositions and methods for treating cancer using immunoconjugates and chemotherapeutic agents

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL265085A (hu) * 1960-05-24
HU165986B (hu) * 1973-02-16 1974-12-28
AR204004A1 (es) * 1973-04-02 1975-11-12 Lilly Co Eli Procedimientos para preparar derivados de vinblastina leurosidina y leurocristina
US4012390A (en) * 1974-10-16 1977-03-15 Eli Lilly And Company Vinblastinoic acid

Also Published As

Publication number Publication date
DK144916C (da) 1982-12-06
SU843753A3 (ru) 1981-06-30
PL202660A1 (pl) 1978-08-28
MX4326E (es) 1982-03-24
CA1082180A (en) 1980-07-22
PL202659A1 (pl) 1978-12-04
PL110671B1 (en) 1980-07-31
DK541077A (da) 1978-06-07
AT353987B (de) 1979-12-10
DE2753791C2 (hu) 1990-08-02
AU513936B2 (en) 1981-01-15
CH632516A5 (de) 1982-10-15
DE2753791A1 (de) 1978-06-08
HU180724B (en) 1983-04-29
ES464765A1 (es) 1979-01-01
HK57281A (en) 1981-11-27
CS195343B2 (en) 1980-01-31
PT67343B (en) 1979-04-26
SE7713587L (sv) 1978-06-07
RO75391A (ro) 1980-11-30
IE46105L (en) 1978-06-06
FR2372839B1 (hu) 1981-11-06
GR67243B (hu) 1981-06-25
PL106522B1 (pl) 1979-12-31
ATA868777A (de) 1980-08-15
RO74137A (ro) 1981-08-30
SU865127A3 (ru) 1981-09-15
IL53506A (en) 1981-09-13
DK144916B (da) 1982-07-05
SE435930B (sv) 1984-10-29
DK541177A (da) 1978-06-07
AU3123077A (en) 1979-06-14
CS195344B2 (en) 1980-01-31
PT67342B (en) 1979-04-26
BG33436A3 (en) 1983-02-15
JPS625160B2 (hu) 1987-02-03
NZ185818A (en) 1979-12-11
CA1103664A (en) 1981-06-23
DD134228A5 (de) 1979-02-14
AT361638B (de) 1981-03-25
FR2372839A1 (fr) 1978-06-30
ZA777237B (en) 1979-07-25
AR218467A1 (es) 1980-06-13
US4096148A (en) 1978-06-20
ATA868877A (de) 1979-05-15
GR67244B (hu) 1981-06-25
ES464764A1 (es) 1979-01-01
PT67343A (en) 1977-12-01
MY8200176A (en) 1982-12-31
NL7713336A (nl) 1978-06-08
GB1590649A (en) 1981-06-03
HU180725B (en) 1983-04-29
IE46105B1 (en) 1983-02-23
SE436036B (sv) 1984-11-05
SE7713586L (sv) 1978-06-07
IL53506A0 (en) 1978-03-10
JPS5371100A (en) 1978-06-24
DK145001C (da) 1982-12-27
BE861417A (fr) 1978-06-02
CH634076A5 (de) 1983-01-14
DK145001B (da) 1982-07-26
BG33437A3 (bg) 1983-02-15
PT67342A (en) 1977-12-01

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