AR218467A1 - Un procedimiento para preparar derivados de 3-espiro-5-"-oxazolidin-2",4"-diona de vincaleucoblastina de 3-espiro-5"-oxazolidin-2",4-diona de 4-desacetilvincaleucoblastina - Google Patents
Un procedimiento para preparar derivados de 3-espiro-5-"-oxazolidin-2",4"-diona de vincaleucoblastina de 3-espiro-5"-oxazolidin-2",4-diona de 4-desacetilvincaleucoblastinaInfo
- Publication number
- AR218467A1 AR218467A1 AR270267A AR27026777A AR218467A1 AR 218467 A1 AR218467 A1 AR 218467A1 AR 270267 A AR270267 A AR 270267A AR 27026777 A AR27026777 A AR 27026777A AR 218467 A1 AR218467 A1 AR 218467A1
- Authority
- AR
- Argentina
- Prior art keywords
- espiro
- diona
- oxazolidin
- vincaleucoblastina
- desacetilvincaleucoblastina
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
- C07D519/04—Dimeric indole alkaloids, e.g. vincaleucoblastine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Indole Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US05/747,575 US4096148A (en) | 1976-12-06 | 1976-12-06 | Oxazolidinedione derivatives of Vinca alkaloids |
Publications (1)
Publication Number | Publication Date |
---|---|
AR218467A1 true AR218467A1 (es) | 1980-06-13 |
Family
ID=25005690
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AR270267A AR218467A1 (es) | 1976-12-06 | 1977-12-06 | Un procedimiento para preparar derivados de 3-espiro-5-"-oxazolidin-2",4"-diona de vincaleucoblastina de 3-espiro-5"-oxazolidin-2",4-diona de 4-desacetilvincaleucoblastina |
Country Status (31)
Country | Link |
---|---|
US (1) | US4096148A (hu) |
JP (1) | JPS5371100A (hu) |
AR (1) | AR218467A1 (hu) |
AT (2) | AT361638B (hu) |
AU (1) | AU513936B2 (hu) |
BE (1) | BE861417A (hu) |
BG (2) | BG33437A3 (hu) |
CA (2) | CA1103664A (hu) |
CH (2) | CH634076A5 (hu) |
CS (2) | CS195344B2 (hu) |
DD (2) | DD134227A5 (hu) |
DE (1) | DE2753791A1 (hu) |
DK (2) | DK144916C (hu) |
ES (2) | ES464764A1 (hu) |
FR (1) | FR2372839A1 (hu) |
GB (1) | GB1590649A (hu) |
GR (2) | GR67243B (hu) |
HK (1) | HK57281A (hu) |
HU (2) | HU180724B (hu) |
IE (1) | IE46105B1 (hu) |
IL (1) | IL53506A (hu) |
MX (1) | MX4326E (hu) |
MY (1) | MY8200176A (hu) |
NL (1) | NL7713336A (hu) |
NZ (1) | NZ185818A (hu) |
PL (2) | PL106522B1 (hu) |
PT (2) | PT67343B (hu) |
RO (2) | RO75391A (hu) |
SE (2) | SE435930B (hu) |
SU (2) | SU865127A3 (hu) |
ZA (1) | ZA777237B (hu) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
HU181874B (en) * | 1977-08-08 | 1983-11-28 | Lilly Co Eli | Process for preparing amides of deacetyl-leurosine and deacetyl-leuroformine |
US4357334A (en) * | 1980-03-20 | 1982-11-02 | Eli Lilly And Company | Use of VLB 3-(2-chloroethyl) carboxamide in treating neoplasms |
US4362664A (en) * | 1980-12-29 | 1982-12-07 | Eli Lilly And Company | Vinblastine oxazolidinedione disulfides and related compounds |
HUT34212A (en) * | 1983-04-29 | 1985-02-28 | Omnichem Sa | Process for the production of new vindblastin conjugates |
HUT76925A (hu) * | 1995-04-04 | 1998-01-28 | MTA Enzimológiai Intézet | Bisz-indol-származékok, eljárás előállításukra és az azokat tartalmazó gyógyszerkészítmények |
EP2289549A3 (en) | 1999-10-01 | 2011-06-15 | Immunogen, Inc. | Immunoconjugates for treating cancer |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NL265085A (hu) * | 1960-05-24 | |||
HU165986B (hu) * | 1973-02-16 | 1974-12-28 | ||
AR204004A1 (es) * | 1973-04-02 | 1975-11-12 | Lilly Co Eli | Procedimientos para preparar derivados de vinblastina leurosidina y leurocristina |
US4012390A (en) * | 1974-10-16 | 1977-03-15 | Eli Lilly And Company | Vinblastinoic acid |
-
1976
- 1976-12-06 US US05/747,575 patent/US4096148A/en not_active Expired - Lifetime
-
1977
- 1977-11-30 SE SE7713587A patent/SE435930B/sv not_active IP Right Cessation
- 1977-11-30 NZ NZ185818A patent/NZ185818A/xx unknown
- 1977-11-30 PT PT67343A patent/PT67343B/pt unknown
- 1977-11-30 CA CA292,072A patent/CA1103664A/en not_active Expired
- 1977-11-30 PT PT67342A patent/PT67342B/pt unknown
- 1977-11-30 RO RO7792261A patent/RO75391A/ro unknown
- 1977-11-30 SE SE7713586A patent/SE436036B/sv not_active IP Right Cessation
- 1977-11-30 CS CS777940A patent/CS195344B2/cs unknown
- 1977-11-30 CA CA292,101A patent/CA1082180A/en not_active Expired
- 1977-11-30 GR GR54897A patent/GR67243B/el unknown
- 1977-11-30 CS CS777939A patent/CS195343B2/cs unknown
- 1977-11-30 RO RO7792262A patent/RO74137A/ro unknown
- 1977-11-30 GB GB49906/77A patent/GB1590649A/en not_active Expired
- 1977-11-30 GR GR54898A patent/GR67244B/el unknown
- 1977-12-01 NL NL7713336A patent/NL7713336A/xx not_active Application Discontinuation
- 1977-12-01 IL IL53506A patent/IL53506A/xx unknown
- 1977-12-02 BG BG037937A patent/BG33437A3/bg unknown
- 1977-12-02 BG BG037936A patent/BG33436A3/xx unknown
- 1977-12-02 FR FR7736437A patent/FR2372839A1/fr active Granted
- 1977-12-02 BE BE1008557A patent/BE861417A/xx not_active IP Right Cessation
- 1977-12-02 DE DE19772753791 patent/DE2753791A1/de active Granted
- 1977-12-02 JP JP14561377A patent/JPS5371100A/ja active Granted
- 1977-12-05 HU HU77EI771A patent/HU180724B/hu not_active IP Right Cessation
- 1977-12-05 ZA ZA00777237A patent/ZA777237B/xx unknown
- 1977-12-05 AT AT868777A patent/AT361638B/de not_active IP Right Cessation
- 1977-12-05 SU SU772549000A patent/SU865127A3/ru active
- 1977-12-05 AT AT868877A patent/AT353987B/de not_active IP Right Cessation
- 1977-12-05 CH CH1486177A patent/CH634076A5/de not_active IP Right Cessation
- 1977-12-05 HU HU77EI7723A patent/HU180725B/hu not_active IP Right Cessation
- 1977-12-05 ES ES464764A patent/ES464764A1/es not_active Expired
- 1977-12-05 MX MX776608U patent/MX4326E/es unknown
- 1977-12-05 PL PL1977202660A patent/PL106522B1/pl unknown
- 1977-12-05 PL PL1977202659A patent/PL110671B1/pl unknown
- 1977-12-05 DK DK541177A patent/DK144916C/da not_active IP Right Cessation
- 1977-12-05 AU AU31230/77A patent/AU513936B2/en not_active Expired
- 1977-12-05 SU SU772549952A patent/SU843753A3/ru active
- 1977-12-05 CH CH1486277A patent/CH632516A5/de not_active IP Right Cessation
- 1977-12-05 DK DK541077A patent/DK145001C/da not_active IP Right Cessation
- 1977-12-05 ES ES464765A patent/ES464765A1/es not_active Expired
- 1977-12-05 IE IE2469/77A patent/IE46105B1/en unknown
- 1977-12-06 DD DD77202423A patent/DD134227A5/xx unknown
- 1977-12-06 DD DD77202424A patent/DD134228A5/xx unknown
- 1977-12-06 AR AR270267A patent/AR218467A1/es active
-
1981
- 1981-11-19 HK HK572/81A patent/HK57281A/xx unknown
-
1982
- 1982-12-30 MY MY176/82A patent/MY8200176A/xx unknown
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