RO75391A - Procedeu de preparare a unor derivati dimeriol al indoldihidroindoldionei - Google Patents

Procedeu de preparare a unor derivati dimeriol al indoldihidroindoldionei

Info

Publication number
RO75391A
RO75391A RO7792261A RO9226177A RO75391A RO 75391 A RO75391 A RO 75391A RO 7792261 A RO7792261 A RO 7792261A RO 9226177 A RO9226177 A RO 9226177A RO 75391 A RO75391 A RO 75391A
Authority
RO
Romania
Prior art keywords
indoldihydroindold
dimeriol
derivatives
preparation
dimeriol derivatives
Prior art date
Application number
RO7792261A
Other languages
English (en)
French (fr)
Inventor
Jean C Miller
Gerald E Gutowski
Original Assignee
Eli Lilly And Co,Us
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly And Co,Us filed Critical Eli Lilly And Co,Us
Publication of RO75391A publication Critical patent/RO75391A/ro

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • C07D519/04—Dimeric indole alkaloids, e.g. vincaleucoblastine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
RO7792261A 1976-12-06 1977-11-30 Procedeu de preparare a unor derivati dimeriol al indoldihidroindoldionei RO75391A (ro)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/747,575 US4096148A (en) 1976-12-06 1976-12-06 Oxazolidinedione derivatives of Vinca alkaloids

Publications (1)

Publication Number Publication Date
RO75391A true RO75391A (ro) 1980-11-30

Family

ID=25005690

Family Applications (2)

Application Number Title Priority Date Filing Date
RO7792262A RO74137A (ro) 1976-12-06 1977-11-30 Procedeu pentru prepararea unor derivati spirooxazolidin dionici
RO7792261A RO75391A (ro) 1976-12-06 1977-11-30 Procedeu de preparare a unor derivati dimeriol al indoldihidroindoldionei

Family Applications Before (1)

Application Number Title Priority Date Filing Date
RO7792262A RO74137A (ro) 1976-12-06 1977-11-30 Procedeu pentru prepararea unor derivati spirooxazolidin dionici

Country Status (31)

Country Link
US (1) US4096148A (ro)
JP (1) JPS5371100A (ro)
AR (1) AR218467A1 (ro)
AT (2) AT353987B (ro)
AU (1) AU513936B2 (ro)
BE (1) BE861417A (ro)
BG (1) BG33436A3 (ro)
CA (2) CA1082180A (ro)
CH (2) CH634076A5 (ro)
CS (2) CS195344B2 (ro)
DD (2) DD134227A5 (ro)
DE (1) DE2753791A1 (ro)
DK (2) DK144916C (ro)
ES (2) ES464765A1 (ro)
FR (1) FR2372839A1 (ro)
GB (1) GB1590649A (ro)
GR (2) GR67243B (ro)
HK (1) HK57281A (ro)
HU (2) HU180725B (ro)
IE (1) IE46105B1 (ro)
IL (1) IL53506A (ro)
MX (1) MX4326E (ro)
MY (1) MY8200176A (ro)
NL (1) NL7713336A (ro)
NZ (1) NZ185818A (ro)
PL (2) PL106522B1 (ro)
PT (2) PT67343B (ro)
RO (2) RO74137A (ro)
SE (2) SE435930B (ro)
SU (2) SU843753A3 (ro)
ZA (1) ZA777237B (ro)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU181874B (en) * 1977-08-08 1983-11-28 Lilly Co Eli Process for preparing amides of deacetyl-leurosine and deacetyl-leuroformine
US4357334A (en) * 1980-03-20 1982-11-02 Eli Lilly And Company Use of VLB 3-(2-chloroethyl) carboxamide in treating neoplasms
US4362664A (en) * 1980-12-29 1982-12-07 Eli Lilly And Company Vinblastine oxazolidinedione disulfides and related compounds
DE3484691D1 (de) * 1983-04-29 1991-07-18 Omnichem Sa Konjugierte vinblastin-verbindungen und ihre derivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zusammensetzungen.
HUT76925A (hu) * 1995-04-04 1998-01-28 MTA Enzimológiai Intézet Bisz-indol-származékok, eljárás előállításukra és az azokat tartalmazó gyógyszerkészítmények
EP2266607A3 (en) 1999-10-01 2011-04-20 Immunogen, Inc. Immunoconjugates for treating cancer

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL125835C (ro) * 1960-05-24
HU165986B (ro) * 1973-02-16 1974-12-28
AR204004A1 (es) * 1973-04-02 1975-11-12 Lilly Co Eli Procedimientos para preparar derivados de vinblastina leurosidina y leurocristina
US4012390A (en) * 1974-10-16 1977-03-15 Eli Lilly And Company Vinblastinoic acid

Also Published As

Publication number Publication date
SE436036B (sv) 1984-11-05
NZ185818A (en) 1979-12-11
DD134227A5 (de) 1979-02-14
DK541077A (da) 1978-06-07
PT67343B (en) 1979-04-26
CH634076A5 (de) 1983-01-14
DK145001B (da) 1982-07-26
ATA868877A (de) 1979-05-15
RO74137A (ro) 1981-08-30
DE2753791A1 (de) 1978-06-08
SU843753A3 (ru) 1981-06-30
US4096148A (en) 1978-06-20
SE7713587L (sv) 1978-06-07
SE7713586L (sv) 1978-06-07
DK145001C (da) 1982-12-27
PL106522B1 (pl) 1979-12-31
HU180724B (en) 1983-04-29
DK144916C (da) 1982-12-06
MX4326E (es) 1982-03-24
JPS5371100A (en) 1978-06-24
ZA777237B (en) 1979-07-25
IE46105B1 (en) 1983-02-23
IL53506A (en) 1981-09-13
DK541177A (da) 1978-06-07
GR67243B (ro) 1981-06-25
AU513936B2 (en) 1981-01-15
AR218467A1 (es) 1980-06-13
AT353987B (de) 1979-12-10
CS195344B2 (en) 1980-01-31
ATA868777A (de) 1980-08-15
ES464764A1 (es) 1979-01-01
PT67343A (en) 1977-12-01
NL7713336A (nl) 1978-06-08
CS195343B2 (en) 1980-01-31
SE435930B (sv) 1984-10-29
FR2372839A1 (fr) 1978-06-30
CH632516A5 (de) 1982-10-15
HU180725B (en) 1983-04-29
BG33436A3 (en) 1983-02-15
ES464765A1 (es) 1979-01-01
JPS625160B2 (ro) 1987-02-03
AT361638B (de) 1981-03-25
PL202659A1 (pl) 1978-12-04
HK57281A (en) 1981-11-27
FR2372839B1 (ro) 1981-11-06
CA1103664A (en) 1981-06-23
SU865127A3 (ru) 1981-09-15
IL53506A0 (en) 1978-03-10
GR67244B (ro) 1981-06-25
PL110671B1 (en) 1980-07-31
AU3123077A (en) 1979-06-14
CA1082180A (en) 1980-07-22
DK144916B (da) 1982-07-05
MY8200176A (en) 1982-12-31
DD134228A5 (de) 1979-02-14
GB1590649A (en) 1981-06-03
PT67342B (en) 1979-04-26
DE2753791C2 (ro) 1990-08-02
IE46105L (en) 1978-06-06
PL202660A1 (pl) 1978-08-28
PT67342A (en) 1977-12-01
BE861417A (fr) 1978-06-02

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