BE861417A - Derives d'oxazolidinedione des alcaloides de vinca, a activite anti-tumorale - Google Patents

Derives d'oxazolidinedione des alcaloides de vinca, a activite anti-tumorale

Info

Publication number
BE861417A
BE861417A BE1008557A BE1008557A BE861417A BE 861417 A BE861417 A BE 861417A BE 1008557 A BE1008557 A BE 1008557A BE 1008557 A BE1008557 A BE 1008557A BE 861417 A BE861417 A BE 861417A
Authority
BE
Belgium
Prior art keywords
tumor activity
vinca alkaloids
oxazolidinedione derivatives
oxazolidinedione
derivatives
Prior art date
Application number
BE1008557A
Other languages
English (en)
French (fr)
Inventor
Jean Corinne Millet
Gerald Edward Gutowski
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of BE861417A publication Critical patent/BE861417A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • C07D519/04—Dimeric indole alkaloids, e.g. vincaleucoblastine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
BE1008557A 1976-12-06 1977-12-02 Derives d'oxazolidinedione des alcaloides de vinca, a activite anti-tumorale BE861417A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/747,575 US4096148A (en) 1976-12-06 1976-12-06 Oxazolidinedione derivatives of Vinca alkaloids

Publications (1)

Publication Number Publication Date
BE861417A true BE861417A (fr) 1978-06-02

Family

ID=25005690

Family Applications (1)

Application Number Title Priority Date Filing Date
BE1008557A BE861417A (fr) 1976-12-06 1977-12-02 Derives d'oxazolidinedione des alcaloides de vinca, a activite anti-tumorale

Country Status (31)

Country Link
US (1) US4096148A (ro)
JP (1) JPS5371100A (ro)
AR (1) AR218467A1 (ro)
AT (2) AT361638B (ro)
AU (1) AU513936B2 (ro)
BE (1) BE861417A (ro)
BG (1) BG33436A3 (ro)
CA (2) CA1082180A (ro)
CH (2) CH632516A5 (ro)
CS (2) CS195344B2 (ro)
DD (2) DD134228A5 (ro)
DE (1) DE2753791A1 (ro)
DK (2) DK144916C (ro)
ES (2) ES464765A1 (ro)
FR (1) FR2372839A1 (ro)
GB (1) GB1590649A (ro)
GR (2) GR67244B (ro)
HK (1) HK57281A (ro)
HU (2) HU180724B (ro)
IE (1) IE46105B1 (ro)
IL (1) IL53506A (ro)
MX (1) MX4326E (ro)
MY (1) MY8200176A (ro)
NL (1) NL7713336A (ro)
NZ (1) NZ185818A (ro)
PL (2) PL110671B1 (ro)
PT (2) PT67343B (ro)
RO (2) RO75391A (ro)
SE (2) SE436036B (ro)
SU (2) SU865127A3 (ro)
ZA (1) ZA777237B (ro)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU181874B (en) * 1977-08-08 1983-11-28 Lilly Co Eli Process for preparing amides of deacetyl-leurosine and deacetyl-leuroformine
US4357334A (en) * 1980-03-20 1982-11-02 Eli Lilly And Company Use of VLB 3-(2-chloroethyl) carboxamide in treating neoplasms
US4362664A (en) * 1980-12-29 1982-12-07 Eli Lilly And Company Vinblastine oxazolidinedione disulfides and related compounds
GR81790B (ro) * 1983-04-29 1984-12-12 Omnichem Sa
HUT76925A (hu) * 1995-04-04 1998-01-28 MTA Enzimológiai Intézet Bisz-indol-származékok, eljárás előállításukra és az azokat tartalmazó gyógyszerkészítmények
AU775373B2 (en) 1999-10-01 2004-07-29 Immunogen, Inc. Compositions and methods for treating cancer using immunoconjugates and chemotherapeutic agents

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL265085A (ro) * 1960-05-24
HU165986B (ro) * 1973-02-16 1974-12-28
AR204004A1 (es) * 1973-04-02 1975-11-12 Lilly Co Eli Procedimientos para preparar derivados de vinblastina leurosidina y leurocristina
US4012390A (en) * 1974-10-16 1977-03-15 Eli Lilly And Company Vinblastinoic acid

Also Published As

Publication number Publication date
HU180724B (en) 1983-04-29
AU3123077A (en) 1979-06-14
NZ185818A (en) 1979-12-11
PL202659A1 (pl) 1978-12-04
SU865127A3 (ru) 1981-09-15
PT67343B (en) 1979-04-26
NL7713336A (nl) 1978-06-08
JPS625160B2 (ro) 1987-02-03
DK541177A (da) 1978-06-07
GB1590649A (en) 1981-06-03
DK144916C (da) 1982-12-06
PL106522B1 (pl) 1979-12-31
PT67342B (en) 1979-04-26
BG33436A3 (en) 1983-02-15
ZA777237B (en) 1979-07-25
GR67243B (ro) 1981-06-25
IE46105L (en) 1978-06-06
SE436036B (sv) 1984-11-05
DE2753791C2 (ro) 1990-08-02
JPS5371100A (en) 1978-06-24
CA1082180A (en) 1980-07-22
AR218467A1 (es) 1980-06-13
FR2372839B1 (ro) 1981-11-06
CS195343B2 (en) 1980-01-31
CH632516A5 (de) 1982-10-15
RO75391A (ro) 1980-11-30
DK145001C (da) 1982-12-27
PL110671B1 (en) 1980-07-31
GR67244B (ro) 1981-06-25
DK145001B (da) 1982-07-26
DE2753791A1 (de) 1978-06-08
ES464765A1 (es) 1979-01-01
MX4326E (es) 1982-03-24
CS195344B2 (en) 1980-01-31
DD134227A5 (de) 1979-02-14
DK144916B (da) 1982-07-05
AT361638B (de) 1981-03-25
SE7713586L (sv) 1978-06-07
CH634076A5 (de) 1983-01-14
ES464764A1 (es) 1979-01-01
CA1103664A (en) 1981-06-23
RO74137A (ro) 1981-08-30
FR2372839A1 (fr) 1978-06-30
MY8200176A (en) 1982-12-31
AU513936B2 (en) 1981-01-15
ATA868777A (de) 1980-08-15
AT353987B (de) 1979-12-10
PL202660A1 (pl) 1978-08-28
SE435930B (sv) 1984-10-29
IE46105B1 (en) 1983-02-23
ATA868877A (de) 1979-05-15
IL53506A (en) 1981-09-13
PT67342A (en) 1977-12-01
DD134228A5 (de) 1979-02-14
US4096148A (en) 1978-06-20
SE7713587L (sv) 1978-06-07
HK57281A (en) 1981-11-27
IL53506A0 (en) 1978-03-10
SU843753A3 (ru) 1981-06-30
HU180725B (en) 1983-04-29
PT67343A (en) 1977-12-01
DK541077A (da) 1978-06-07

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Legal Events

Date Code Title Description
RE20 Patent expired

Owner name: ELI LILLY AND CY

Effective date: 19971202