HK57281A - Derivatives of vinblastine and related vinca alkaloids and their use in pharmaceutical compositions - Google Patents

Derivatives of vinblastine and related vinca alkaloids and their use in pharmaceutical compositions

Info

Publication number
HK57281A
HK57281A HK572/81A HK57281A HK57281A HK 57281 A HK57281 A HK 57281A HK 572/81 A HK572/81 A HK 572/81A HK 57281 A HK57281 A HK 57281A HK 57281 A HK57281 A HK 57281A
Authority
HK
Hong Kong
Prior art keywords
vinblastine
derivatives
pharmaceutical compositions
vinca alkaloids
related vinca
Prior art date
Application number
HK572/81A
Other languages
English (en)
Inventor
J C Miller
G E Gutowski
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of HK57281A publication Critical patent/HK57281A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D519/00Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • C07D519/04Dimeric indole alkaloids, e.g. vincaleucoblastine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Indole Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
HK572/81A 1976-12-06 1981-11-19 Derivatives of vinblastine and related vinca alkaloids and their use in pharmaceutical compositions HK57281A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/747,575 US4096148A (en) 1976-12-06 1976-12-06 Oxazolidinedione derivatives of Vinca alkaloids

Publications (1)

Publication Number Publication Date
HK57281A true HK57281A (en) 1981-11-27

Family

ID=25005690

Family Applications (1)

Application Number Title Priority Date Filing Date
HK572/81A HK57281A (en) 1976-12-06 1981-11-19 Derivatives of vinblastine and related vinca alkaloids and their use in pharmaceutical compositions

Country Status (31)

Country Link
US (1) US4096148A (hu)
JP (1) JPS5371100A (hu)
AR (1) AR218467A1 (hu)
AT (2) AT353987B (hu)
AU (1) AU513936B2 (hu)
BE (1) BE861417A (hu)
BG (2) BG33436A3 (hu)
CA (2) CA1103664A (hu)
CH (2) CH632516A5 (hu)
CS (2) CS195343B2 (hu)
DD (2) DD134228A5 (hu)
DE (1) DE2753791A1 (hu)
DK (2) DK144916C (hu)
ES (2) ES464765A1 (hu)
FR (1) FR2372839A1 (hu)
GB (1) GB1590649A (hu)
GR (2) GR67244B (hu)
HK (1) HK57281A (hu)
HU (2) HU180724B (hu)
IE (1) IE46105B1 (hu)
IL (1) IL53506A (hu)
MX (1) MX4326E (hu)
MY (1) MY8200176A (hu)
NL (1) NL7713336A (hu)
NZ (1) NZ185818A (hu)
PL (2) PL110671B1 (hu)
PT (2) PT67343B (hu)
RO (2) RO75391A (hu)
SE (2) SE435930B (hu)
SU (2) SU865127A3 (hu)
ZA (1) ZA777237B (hu)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU181874B (en) * 1977-08-08 1983-11-28 Lilly Co Eli Process for preparing amides of deacetyl-leurosine and deacetyl-leuroformine
US4357334A (en) * 1980-03-20 1982-11-02 Eli Lilly And Company Use of VLB 3-(2-chloroethyl) carboxamide in treating neoplasms
US4362664A (en) * 1980-12-29 1982-12-07 Eli Lilly And Company Vinblastine oxazolidinedione disulfides and related compounds
EP0124502B1 (fr) * 1983-04-29 1991-06-12 OMNICHEM Société anonyme Nouveaux conjugués de la vinblastine et de ses dérivés, procédé pour leur préparation et compositions pharmaceutiques contenant ces conjugués
HUT76925A (hu) * 1995-04-04 1998-01-28 MTA Enzimológiai Intézet Bisz-indol-származékok, eljárás előállításukra és az azokat tartalmazó gyógyszerkészítmények
WO2001024763A2 (en) 1999-10-01 2001-04-12 Immunogen, Inc. Compositions and methods for treating cancer using immunoconjugates and chemotherapeutic agents

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT649883A (hu) * 1960-05-24
HU165986B (hu) * 1973-02-16 1974-12-28
AR204004A1 (es) * 1973-04-02 1975-11-12 Lilly Co Eli Procedimientos para preparar derivados de vinblastina leurosidina y leurocristina
US4012390A (en) * 1974-10-16 1977-03-15 Eli Lilly And Company Vinblastinoic acid

Also Published As

Publication number Publication date
GR67244B (hu) 1981-06-25
JPS625160B2 (hu) 1987-02-03
BG33437A3 (bg) 1983-02-15
IL53506A0 (en) 1978-03-10
PT67343B (en) 1979-04-26
GR67243B (hu) 1981-06-25
US4096148A (en) 1978-06-20
CA1103664A (en) 1981-06-23
DK145001C (da) 1982-12-27
DK144916B (da) 1982-07-05
HU180725B (en) 1983-04-29
PT67342A (en) 1977-12-01
DK144916C (da) 1982-12-06
BE861417A (fr) 1978-06-02
MX4326E (es) 1982-03-24
SU843753A3 (ru) 1981-06-30
RO74137A (ro) 1981-08-30
CS195343B2 (en) 1980-01-31
CH632516A5 (de) 1982-10-15
SE7713587L (sv) 1978-06-07
AT361638B (de) 1981-03-25
PT67342B (en) 1979-04-26
SE435930B (sv) 1984-10-29
SE436036B (sv) 1984-11-05
ATA868877A (de) 1979-05-15
ES464765A1 (es) 1979-01-01
JPS5371100A (en) 1978-06-24
IL53506A (en) 1981-09-13
HU180724B (en) 1983-04-29
DD134228A5 (de) 1979-02-14
IE46105L (en) 1978-06-06
AU3123077A (en) 1979-06-14
BG33436A3 (en) 1983-02-15
DD134227A5 (de) 1979-02-14
GB1590649A (en) 1981-06-03
AR218467A1 (es) 1980-06-13
ZA777237B (en) 1979-07-25
DE2753791C2 (hu) 1990-08-02
DK145001B (da) 1982-07-26
FR2372839B1 (hu) 1981-11-06
SU865127A3 (ru) 1981-09-15
PL110671B1 (en) 1980-07-31
SE7713586L (sv) 1978-06-07
PT67343A (en) 1977-12-01
AT353987B (de) 1979-12-10
MY8200176A (en) 1982-12-31
PL202660A1 (pl) 1978-08-28
NL7713336A (nl) 1978-06-08
DK541077A (da) 1978-06-07
PL202659A1 (pl) 1978-12-04
DE2753791A1 (de) 1978-06-08
CS195344B2 (en) 1980-01-31
CH634076A5 (de) 1983-01-14
PL106522B1 (pl) 1979-12-31
FR2372839A1 (fr) 1978-06-30
RO75391A (ro) 1980-11-30
IE46105B1 (en) 1983-02-23
DK541177A (da) 1978-06-07
AU513936B2 (en) 1981-01-15
CA1082180A (en) 1980-07-22
NZ185818A (en) 1979-12-11
ATA868777A (de) 1980-08-15
ES464764A1 (es) 1979-01-01

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