CZ420598A3 - Indolinový derivát k použití jako antagonista 5-HT-2C receptoru - Google Patents
Indolinový derivát k použití jako antagonista 5-HT-2C receptoru Download PDFInfo
- Publication number
- CZ420598A3 CZ420598A3 CZ984205A CZ420598A CZ420598A3 CZ 420598 A3 CZ420598 A3 CZ 420598A3 CZ 984205 A CZ984205 A CZ 984205A CZ 420598 A CZ420598 A CZ 420598A CZ 420598 A3 CZ420598 A3 CZ 420598A3
- Authority
- CZ
- Czechia
- Prior art keywords
- compound
- methyl
- compound according
- yloxy
- formula
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9612883.0A GB9612883D0 (en) | 1996-06-20 | 1996-06-20 | Novel compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CZ420598A3 true CZ420598A3 (cs) | 1999-06-16 |
Family
ID=10795575
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CZ984205A CZ420598A3 (cs) | 1996-06-20 | 1997-06-16 | Indolinový derivát k použití jako antagonista 5-HT-2C receptoru |
Country Status (33)
| Country | Link |
|---|---|
| US (1) | US6369060B1 (https=) |
| EP (1) | EP0912554B1 (https=) |
| JP (1) | JP2000512306A (https=) |
| KR (1) | KR20000022045A (https=) |
| CN (1) | CN1229408A (https=) |
| AP (2) | AP9801410A0 (https=) |
| AR (1) | AR008243A1 (https=) |
| AT (1) | ATE228514T1 (https=) |
| AU (1) | AU718597B2 (https=) |
| BG (1) | BG103089A (https=) |
| BR (1) | BR9709911A (https=) |
| CA (1) | CA2258240A1 (https=) |
| CO (1) | CO4890847A1 (https=) |
| CZ (1) | CZ420598A3 (https=) |
| DE (1) | DE69717449T2 (https=) |
| DZ (1) | DZ2250A1 (https=) |
| EA (1) | EA001780B1 (https=) |
| ES (1) | ES2187783T3 (https=) |
| GB (1) | GB9612883D0 (https=) |
| HU (1) | HUP9903439A3 (https=) |
| ID (1) | ID19433A (https=) |
| IL (1) | IL127417A0 (https=) |
| MA (1) | MA24214A1 (https=) |
| NO (1) | NO985972D0 (https=) |
| NZ (1) | NZ333229A (https=) |
| OA (1) | OA10944A (https=) |
| PE (1) | PE86698A1 (https=) |
| PL (1) | PL330796A1 (https=) |
| SK (1) | SK282706B6 (https=) |
| TR (1) | TR199802661T2 (https=) |
| TW (1) | TW382015B (https=) |
| WO (1) | WO1997048699A1 (https=) |
| ZA (1) | ZA975415B (https=) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1999043650A2 (en) * | 1998-02-25 | 1999-09-02 | Smithkline Beecham Plc | Process(es) for the preparation of 6-trifluoromethyl-indoline derivatives |
| GB0019950D0 (en) * | 2000-08-12 | 2000-09-27 | Smithkline Beecham Plc | Compounds |
| EP1451176A2 (en) * | 2001-11-28 | 2004-09-01 | PHARMACIA & UPJOHN COMPANY | Benzazepine derivatives and their use as 5-ht ligands |
| US7291738B2 (en) * | 2002-03-04 | 2007-11-06 | Pharmacia & Upjohn Company | Therapeutic compounds |
| KR101062376B1 (ko) * | 2008-04-10 | 2011-09-06 | 한국화학연구원 | 신규 인돌 카르복실산 비스피리딜 카르복사마이드 유도체,이의 제조방법 및 이를 유효성분으로 함유하는 조성물 |
| EP2387611A4 (en) | 2009-01-16 | 2012-08-15 | Massachusetts Inst Technology | DIAGNOSIS AND TREATMENT OF AUTISM SPECTRUM DISORDERS |
| ES2847883T3 (es) | 2010-12-17 | 2021-08-04 | Glaxo Group Ltd | Uso de inhibidores de LP-PLA2 en el tratamiento y prevención de enfermedades oculares |
| WO2014046544A1 (en) | 2012-09-21 | 2014-03-27 | Aapa B.V. | Substituted 3-heteroaryloxy-3-(hetero)aryl-propylamines as serotonin transporter and serotonin ht2c receptor modulators |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1989001333A1 (en) | 1987-08-07 | 1989-02-23 | The Australian National University | IMIDAZO[1,2-b]PYRIDAZINES |
| EP0656003A1 (en) | 1992-08-20 | 1995-06-07 | Smithkline Beecham Plc | Condensed indole derivatives as 5ht2c and 5ht2b antagonists |
| GB9313913D0 (en) * | 1993-07-06 | 1993-08-18 | Smithkline Beecham Plc | Novel compounds |
| DK0808312T3 (da) * | 1995-02-02 | 2001-02-12 | Smithkline Beecham Plc | Indolderivater som 5-HT-receptorantagonist |
| GB9607219D0 (en) * | 1996-04-04 | 1996-06-12 | Smithkline Beecham Plc | Novel compounds |
| GB9615767D0 (en) * | 1996-07-26 | 1996-09-04 | Smithkline Beecham Plc | Novel treatment |
-
1996
- 1996-06-20 GB GBGB9612883.0A patent/GB9612883D0/en active Pending
-
1997
- 1997-06-16 CA CA002258240A patent/CA2258240A1/en not_active Abandoned
- 1997-06-16 DE DE69717449T patent/DE69717449T2/de not_active Expired - Fee Related
- 1997-06-16 NZ NZ333229A patent/NZ333229A/xx unknown
- 1997-06-16 PL PL97330796A patent/PL330796A1/xx unknown
- 1997-06-16 CN CN97197311A patent/CN1229408A/zh active Pending
- 1997-06-16 CZ CZ984205A patent/CZ420598A3/cs unknown
- 1997-06-16 US US09/202,780 patent/US6369060B1/en not_active Expired - Fee Related
- 1997-06-16 ES ES97928224T patent/ES2187783T3/es not_active Expired - Lifetime
- 1997-06-16 HU HU9903439A patent/HUP9903439A3/hu unknown
- 1997-06-16 AU AU32602/97A patent/AU718597B2/en not_active Ceased
- 1997-06-16 EA EA199900043A patent/EA001780B1/ru not_active IP Right Cessation
- 1997-06-16 KR KR1019980710443A patent/KR20000022045A/ko not_active Ceased
- 1997-06-16 AP APAP/P/1998/001410A patent/AP9801410A0/en unknown
- 1997-06-16 WO PCT/EP1997/003156 patent/WO1997048699A1/en not_active Ceased
- 1997-06-16 IL IL12741797A patent/IL127417A0/xx unknown
- 1997-06-16 EP EP97928224A patent/EP0912554B1/en not_active Expired - Lifetime
- 1997-06-16 TR TR1998/02661T patent/TR199802661T2/xx unknown
- 1997-06-16 AT AT97928224T patent/ATE228514T1/de not_active IP Right Cessation
- 1997-06-16 JP JP10502259A patent/JP2000512306A/ja active Pending
- 1997-06-16 BR BR9709911A patent/BR9709911A/pt unknown
- 1997-06-16 SK SK1752-98A patent/SK282706B6/sk unknown
- 1997-06-18 DZ DZ970100A patent/DZ2250A1/fr active
- 1997-06-18 PE PE1997000510A patent/PE86698A1/es not_active Application Discontinuation
- 1997-06-18 MA MA24666A patent/MA24214A1/fr unknown
- 1997-06-18 AP APAP/P/1997/001037A patent/AP745A/en active
- 1997-06-18 AR ARP970102673A patent/AR008243A1/es unknown
- 1997-06-19 TW TW086108551A patent/TW382015B/zh not_active IP Right Cessation
- 1997-06-19 ZA ZA975415A patent/ZA975415B/xx unknown
- 1997-06-20 ID IDP972126A patent/ID19433A/id unknown
- 1997-06-20 CO CO97034431A patent/CO4890847A1/es unknown
-
1998
- 1998-12-18 NO NO985972A patent/NO985972D0/no unknown
- 1998-12-18 OA OA9800245A patent/OA10944A/en unknown
-
1999
- 1999-01-15 BG BG103089A patent/BG103089A/xx unknown
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PD00 | Pending as of 2000-06-30 in czech republic |