CZ308398A3 - Způsob přípravy flukonazolu - Google Patents

Způsob přípravy flukonazolu Download PDF

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Publication number
CZ308398A3
CZ308398A3 CZ983083A CZ308398A CZ308398A3 CZ 308398 A3 CZ308398 A3 CZ 308398A3 CZ 983083 A CZ983083 A CZ 983083A CZ 308398 A CZ308398 A CZ 308398A CZ 308398 A3 CZ308398 A3 CZ 308398A3
Authority
CZ
Czechia
Prior art keywords
formula
reaction
fluconazole
compound
preparation
Prior art date
Application number
CZ983083A
Other languages
Czech (cs)
English (en)
Inventor
Yong Fan Kim
Geal Jung Yoon
Myung Hwan Park
Original Assignee
Dae Woong Pharmaceutical Co., Ltd.
Dae Woong Chemical Co. Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dae Woong Pharmaceutical Co., Ltd., Dae Woong Chemical Co. Ltd. filed Critical Dae Woong Pharmaceutical Co., Ltd.
Publication of CZ308398A3 publication Critical patent/CZ308398A3/cs

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CZ983083A 1997-01-29 1998-01-24 Způsob přípravy flukonazolu CZ308398A3 (cs)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
KR1019970002700A KR100194945B1 (ko) 1997-01-29 1997-01-29 플루코나졸의 제조방법

Publications (1)

Publication Number Publication Date
CZ308398A3 true CZ308398A3 (cs) 1999-03-17

Family

ID=19495904

Family Applications (1)

Application Number Title Priority Date Filing Date
CZ983083A CZ308398A3 (cs) 1997-01-29 1998-01-24 Způsob přípravy flukonazolu

Country Status (8)

Country Link
EP (1) EP1001947A1 (fr)
KR (1) KR100194945B1 (fr)
AU (1) AU5882398A (fr)
CZ (1) CZ308398A3 (fr)
HU (1) HUP0000726A3 (fr)
PL (1) PL329117A1 (fr)
SK (1) SK133298A3 (fr)
WO (1) WO1998032744A1 (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100341688B1 (ko) * 1999-04-16 2002-06-24 윤재승 플루코나졸의 제조방법
CA2439310C (fr) 2001-03-23 2009-09-29 Richter Gedeon Vegyeszeti Gyar Rt. Methode de preparation de fluconazole et de ses modifications cristallines
BR102013027313B1 (pt) * 2013-10-23 2019-06-18 Iharabras S.A. Indústrias Químicas Processo para a preparação seletiva de (1h-1,2,4-triazol-1-il) alcanóis, composto hidrazinil alcanol obtido por tal processo e seu uso
BR112018009915A2 (pt) * 2015-11-17 2018-11-13 Dow Agrosciences Llc 4-((6-(2-(2,4-difluorfenil)-1,1-diflúor-2-hidróxi-3-(1h-1,2,4-triazol-1-il)propil)piridin-3-il)óxi)benzonitrila e processos de preparação
EP3377475A4 (fr) * 2015-11-17 2019-04-10 Dow Agrosciences Llc 4-((6-2-(2,4-difluorophényl)-1,1-difluoro-2-hydroxy-3-(1h-1,2,4-triazol-1-yl)propyl)pyridin-3-yl)oxy)benzonitrile et procédés de préparation
CN106749055A (zh) * 2016-12-19 2017-05-31 苏州天马精细化学品股份有限公司 一种氟康唑的制备方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3262386D1 (en) * 1981-06-06 1985-03-28 Pfizer Ltd Antifungal agents, processes for their preparation, and pharmaceutical compositions containing them
CA2106032C (fr) * 1993-09-13 1995-11-07 Gamini Weeratunga Methodes pour la fabrication de la fluoconazole et de ses derives, composes intermediaires utiles pour leur fabrication, et combinaisons comportant de la fluoconazole
CA2139079C (fr) * 1994-12-23 1996-05-28 K.S. Keshava Murthy Procede commercial pour la fabrication de fluconazole et intermediaires utiles a cette fin

Also Published As

Publication number Publication date
HUP0000726A3 (en) 2002-02-28
EP1001947A1 (fr) 2000-05-24
WO1998032744A1 (fr) 1998-07-30
SK133298A3 (en) 1999-04-13
HUP0000726A2 (hu) 2000-11-28
KR19980066917A (ko) 1998-10-15
AU5882398A (en) 1998-08-18
KR100194945B1 (ko) 1999-06-15
PL329117A1 (en) 1999-03-15

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Legal Events

Date Code Title Description
PD00 Pending as of 2000-06-30 in czech republic