HUP0000726A3 - Process for manufacturing fluconazole - Google Patents
Process for manufacturing fluconazoleInfo
- Publication number
- HUP0000726A3 HUP0000726A3 HU0000726A HUP0000726A HUP0000726A3 HU P0000726 A3 HUP0000726 A3 HU P0000726A3 HU 0000726 A HU0000726 A HU 0000726A HU P0000726 A HUP0000726 A HU P0000726A HU P0000726 A3 HUP0000726 A3 HU P0000726A3
- Authority
- HU
- Hungary
- Prior art keywords
- fluconazole
- manufacturing
- manufacturing fluconazole
- Prior art date
Links
- RFHAOTPXVQNOHP-UHFFFAOYSA-N fluconazole Chemical compound C1=NC=NN1CC(C=1C(=CC(F)=CC=1)F)(O)CN1C=NC=N1 RFHAOTPXVQNOHP-UHFFFAOYSA-N 0.000 title 1
- 229960004884 fluconazole Drugs 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 238000000034 method Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR1019970002700A KR100194945B1 (ko) | 1997-01-29 | 1997-01-29 | 플루코나졸의 제조방법 |
| PCT/KR1998/000018 WO1998032744A1 (en) | 1997-01-29 | 1998-01-24 | Process for manufacturing fluconazole |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| HUP0000726A2 HUP0000726A2 (hu) | 2000-11-28 |
| HUP0000726A3 true HUP0000726A3 (en) | 2002-02-28 |
Family
ID=19495904
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HU0000726A HUP0000726A3 (en) | 1997-01-29 | 1998-01-24 | Process for manufacturing fluconazole |
Country Status (8)
| Country | Link |
|---|---|
| EP (1) | EP1001947A1 (hu) |
| KR (1) | KR100194945B1 (hu) |
| AU (1) | AU5882398A (hu) |
| CZ (1) | CZ308398A3 (hu) |
| HU (1) | HUP0000726A3 (hu) |
| PL (1) | PL329117A1 (hu) |
| SK (1) | SK133298A3 (hu) |
| WO (1) | WO1998032744A1 (hu) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR100341688B1 (ko) * | 1999-04-16 | 2002-06-24 | 윤재승 | 플루코나졸의 제조방법 |
| CA2439310C (en) | 2001-03-23 | 2009-09-29 | Richter Gedeon Vegyeszeti Gyar Rt. | Process for preparing fluconazole and its crystal modifications |
| BR102013027313B1 (pt) * | 2013-10-23 | 2019-06-18 | Iharabras S.A. Indústrias Químicas | Processo para a preparação seletiva de (1h-1,2,4-triazol-1-il) alcanóis, composto hidrazinil alcanol obtido por tal processo e seu uso |
| BR112018009915A2 (pt) * | 2015-11-17 | 2018-11-13 | Dow Agrosciences Llc | 4-((6-(2-(2,4-difluorfenil)-1,1-diflúor-2-hidróxi-3-(1h-1,2,4-triazol-1-il)propil)piridin-3-il)óxi)benzonitrila e processos de preparação |
| EP3377475A4 (en) * | 2015-11-17 | 2019-04-10 | Dow Agrosciences Llc | 4 - ((6-2- (2,4-difluorophenyl) -1,1-DIFLUORO-2-HYDROXY-3- (1H-1,2,4-TRIAZOL-1-YL) PROPYL) PYRIDIN-3-YL ) OXY) BENZONITRILE AND METHODS OF PREPARATION |
| CN106749055A (zh) * | 2016-12-19 | 2017-05-31 | 苏州天马精细化学品股份有限公司 | 一种氟康唑的制备方法 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3262386D1 (en) * | 1981-06-06 | 1985-03-28 | Pfizer Ltd | Antifungal agents, processes for their preparation, and pharmaceutical compositions containing them |
| CA2106032C (en) * | 1993-09-13 | 1995-11-07 | Gamini Weeratunga | Methods for the manufacture of fluconazole and forms thereof, intermediates useful in the manufacture thereof, and combinations comprising fluconazole |
| CA2139079C (en) * | 1994-12-23 | 1996-05-28 | K.S. Keshava Murthy | Commercial process for the manufacture of fluconazole and intermediates useful in the manufacture thereof |
-
1997
- 1997-01-29 KR KR1019970002700A patent/KR100194945B1/ko not_active IP Right Cessation
-
1998
- 1998-01-24 AU AU58823/98A patent/AU5882398A/en not_active Abandoned
- 1998-01-24 HU HU0000726A patent/HUP0000726A3/hu unknown
- 1998-01-24 SK SK1332-98A patent/SK133298A3/sk unknown
- 1998-01-24 CZ CZ983083A patent/CZ308398A3/cs unknown
- 1998-01-24 EP EP98902274A patent/EP1001947A1/en not_active Withdrawn
- 1998-01-24 WO PCT/KR1998/000018 patent/WO1998032744A1/en not_active Application Discontinuation
- 1998-01-24 PL PL98329117A patent/PL329117A1/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP1001947A1 (en) | 2000-05-24 |
| WO1998032744A1 (en) | 1998-07-30 |
| SK133298A3 (en) | 1999-04-13 |
| HUP0000726A2 (hu) | 2000-11-28 |
| KR19980066917A (ko) | 1998-10-15 |
| CZ308398A3 (cs) | 1999-03-17 |
| AU5882398A (en) | 1998-08-18 |
| KR100194945B1 (ko) | 1999-06-15 |
| PL329117A1 (en) | 1999-03-15 |
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