CZ291349B6 - Léčivo pro prevenci nebo léčbu závislosti na benzodiazepinech - Google Patents

Léčivo pro prevenci nebo léčbu závislosti na benzodiazepinech Download PDF

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Publication number
CZ291349B6
CZ291349B6 CZ19972405A CZ240597A CZ291349B6 CZ 291349 B6 CZ291349 B6 CZ 291349B6 CZ 19972405 A CZ19972405 A CZ 19972405A CZ 240597 A CZ240597 A CZ 240597A CZ 291349 B6 CZ291349 B6 CZ 291349B6
Authority
CZ
Czechia
Prior art keywords
melatonin
medicament
benzodiazepine
treatment
preparation
Prior art date
Application number
CZ19972405A
Other languages
Czech (cs)
English (en)
Other versions
CZ240597A3 (cs
Inventor
Nava Zisapel
Original Assignee
Neurim Pharmaceuticals Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/381,535 external-priority patent/US6469044B1/en
Application filed by Neurim Pharmaceuticals Ltd. filed Critical Neurim Pharmaceuticals Ltd.
Publication of CZ240597A3 publication Critical patent/CZ240597A3/cs
Publication of CZ291349B6 publication Critical patent/CZ291349B6/cs

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
    • A61K31/4045—Indole-alkylamines; Amides thereof, e.g. serotonin, melatonin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/02—Antidotes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Epidemiology (AREA)
  • Psychiatry (AREA)
  • Addiction (AREA)
  • Anesthesiology (AREA)
  • Toxicology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
CZ19972405A 1995-02-01 1996-01-29 Léčivo pro prevenci nebo léčbu závislosti na benzodiazepinech CZ291349B6 (cs)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/381,535 US6469044B1 (en) 1995-02-01 1995-02-01 Method for treating patients suffering from drug dependencies which lead to plasma melationin deficiencies
EP95303853A EP0724878B1 (en) 1995-02-01 1995-06-06 Use of melatonin for treating patients suffering from drug dependencies

Publications (2)

Publication Number Publication Date
CZ240597A3 CZ240597A3 (cs) 1998-01-14
CZ291349B6 true CZ291349B6 (cs) 2003-02-12

Family

ID=26140195

Family Applications (1)

Application Number Title Priority Date Filing Date
CZ19972405A CZ291349B6 (cs) 1995-02-01 1996-01-29 Léčivo pro prevenci nebo léčbu závislosti na benzodiazepinech

Country Status (22)

Country Link
JP (1) JP4516159B2 (da)
CN (1) CN1083263C (da)
AT (1) AT408188B (da)
AU (1) AU695366B2 (da)
BG (1) BG62876B1 (da)
BR (1) BR9607169A (da)
CZ (1) CZ291349B6 (da)
DK (1) DK176081B1 (da)
EE (1) EE03384B1 (da)
FI (1) FI119586B (da)
IS (1) IS1980B (da)
LU (1) LU90118B1 (da)
LV (1) LV11940B (da)
MD (1) MD1716C2 (da)
NO (1) NO312814B1 (da)
NZ (1) NZ298878A (da)
PL (1) PL183148B1 (da)
SI (1) SI9620022A (da)
SK (1) SK284521B6 (da)
TR (1) TR199700723T1 (da)
TW (1) TW483757B (da)
WO (1) WO1996023496A1 (da)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK1272177T3 (da) 2000-01-05 2007-08-06 Neurim Pharma 1991 Fremgangsmåde og formulering til behandling af resistens over for antihypertensiva og forbundne tilstande
IL149377A (en) * 2002-04-28 2012-10-31 Neurim Pharma 1991 Pharmaceutical formulation comprising melatonin for the potentiation of the effect of hypnotic compounds
IL155666A (en) 2003-04-29 2013-12-31 Neurim Pharma 1991 Insomnia treatment
US9119846B2 (en) 2003-04-29 2015-09-01 Neurim Pharmaceuticals (1991) Ltd. Method and composition for enhancing cognition in alzheimer's patients
EP3620794A1 (en) * 2012-01-26 2020-03-11 Vanda Pharmaceuticals Inc. Determining a circadian rhythm
US11918557B2 (en) 2012-01-26 2024-03-05 Vanda Pharmaceuticals Inc. Treatment of circadian rhythm disorders
MX2015007909A (es) 2012-12-18 2016-04-25 Vanda Pharmaceuticals Inc Tratamiento de trastornos del ritmo circadiano.
US10376487B2 (en) 2013-11-12 2019-08-13 Vanda Pharmaceuticals Inc. Method of treatment
US11090285B2 (en) 2013-11-12 2021-08-17 Vanda Pharmaceuticals Inc Treatment of circadian rhythm disorders
ES2828034T3 (es) * 2016-10-31 2021-05-25 Neurim Pharma 1991 Minicomprimidos de melatonina y método de fabricación de los mismos

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK0518468T3 (da) * 1991-05-09 2000-01-31 Neurim Pharma 1991 Melatoninholdige sammensætninger
IT1251544B (it) * 1991-05-13 1995-05-17 Gabriele Biella Composizioni farmaceutiche attive nella terapia dei disturbi del sonno comprendenti melatonina o un suo derivato in associazione con un derivato benzodiazepinico

Also Published As

Publication number Publication date
BG62876B1 (bg) 2000-10-31
CN1172431A (zh) 1998-02-04
JPH10513177A (ja) 1998-12-15
PL321630A1 (en) 1997-12-08
LV11940B (en) 1998-05-20
SK103097A3 (en) 1998-01-14
AT408188B (de) 2001-09-25
CN1083263C (zh) 2002-04-24
IS4532A (is) 1997-07-25
MD1716B2 (en) 2001-08-31
EE03384B1 (et) 2001-04-16
BR9607169A (pt) 1997-11-11
TR199700723T1 (xx) 1998-02-21
MX9705856A (es) 1998-07-31
FI973185A0 (fi) 1997-07-31
CZ240597A3 (cs) 1998-01-14
SK284521B6 (sk) 2005-05-05
NO312814B1 (no) 2002-07-08
AU695366B2 (en) 1998-08-13
ATA901396A (de) 2001-02-15
NO973531D0 (no) 1997-07-31
WO1996023496A1 (en) 1996-08-08
MD1716C2 (ro) 2002-02-28
JP4516159B2 (ja) 2010-08-04
FI973185A (fi) 1997-09-30
AU4457496A (en) 1996-08-21
IS1980B (is) 2005-01-14
NZ298878A (en) 1999-05-28
DK176081B1 (da) 2006-04-18
NO973531L (no) 1997-09-30
LU90118B1 (fr) 1997-11-13
DK89697A (da) 1997-07-30
PL183148B1 (pl) 2002-05-31
TW483757B (en) 2002-04-21
FI119586B (fi) 2009-01-15
EE9700166A (et) 1998-02-16
BG101803A (en) 1998-04-30
MD970254A (en) 1999-05-31
SI9620022A (sl) 1998-10-31
LV11940A (lv) 1998-01-20

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Legal Events

Date Code Title Description
PD00 Pending as of 2000-06-30 in czech republic
MK4A Patent expired

Effective date: 20160129