CZ204499A3 - Přípravek obsahující polymorfní formy desferrioxaminu a způsob jeho přípravy - Google Patents
Přípravek obsahující polymorfní formy desferrioxaminu a způsob jeho přípravy Download PDFInfo
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- CZ204499A3 CZ204499A3 CZ992044A CZ204499A CZ204499A3 CZ 204499 A3 CZ204499 A3 CZ 204499A3 CZ 992044 A CZ992044 A CZ 992044A CZ 204499 A CZ204499 A CZ 204499A CZ 204499 A3 CZ204499 A3 CZ 204499A3
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- CZ
- Czechia
- Prior art keywords
- desferrioxamine
- decanesulfonate
- salt
- crystal
- oil
- Prior art date
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- UBQYURCVBFRUQT-UHFFFAOYSA-N N-benzoyl-Ferrioxamine B Chemical compound CC(=O)N(O)CCCCCNC(=O)CCC(=O)N(O)CCCCCNC(=O)CCC(=O)N(O)CCCCCN UBQYURCVBFRUQT-UHFFFAOYSA-N 0.000 title claims abstract description 62
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- 244000098338 Triticum aestivum Species 0.000 description 1
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- WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 description 1
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- TWXDDNPPQUTEOV-UHFFFAOYSA-N hydron;n-methyl-1-phenylpropan-2-amine;chloride Chemical compound Cl.CNC(C)CC1=CC=CC=C1 TWXDDNPPQUTEOV-UHFFFAOYSA-N 0.000 description 1
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- 101150003180 metB gene Proteins 0.000 description 1
- 230000009401 metastasis Effects 0.000 description 1
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- 150000002825 nitriles Chemical class 0.000 description 1
- 239000002736 nonionic surfactant Substances 0.000 description 1
- LHQXHHDBJMMPCQ-UHFFFAOYSA-N octane-2-sulfonic acid Chemical compound CCCCCCC(C)S(O)(=O)=O LHQXHHDBJMMPCQ-UHFFFAOYSA-N 0.000 description 1
- 229940049964 oleate Drugs 0.000 description 1
- ZQPPMHVWECSIRJ-KTKRTIGZSA-M oleate Chemical compound CCCCCCCC\C=C/CCCCCCCC([O-])=O ZQPPMHVWECSIRJ-KTKRTIGZSA-M 0.000 description 1
- 239000005416 organic matter Substances 0.000 description 1
- 229910052760 oxygen Inorganic materials 0.000 description 1
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- 238000011170 pharmaceutical development Methods 0.000 description 1
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- WVDDGKGOMKODPV-ZQBYOMGUSA-N phenyl(114C)methanol Chemical compound O[14CH2]C1=CC=CC=C1 WVDDGKGOMKODPV-ZQBYOMGUSA-N 0.000 description 1
- 150000003904 phospholipids Chemical class 0.000 description 1
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- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 description 1
- 125000001436 propyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])[H] 0.000 description 1
- 235000018102 proteins Nutrition 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
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- 239000011780 sodium chloride Substances 0.000 description 1
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- 239000011877 solvent mixture Substances 0.000 description 1
- 229940035044 sorbitan monolaurate Drugs 0.000 description 1
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- 239000008174 sterile solution Substances 0.000 description 1
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- 150000008054 sulfonate salts Chemical class 0.000 description 1
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- 239000011593 sulfur Substances 0.000 description 1
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- YBRBMKDOPFTVDT-UHFFFAOYSA-N tert-butylamine Chemical compound CC(C)(C)N YBRBMKDOPFTVDT-UHFFFAOYSA-N 0.000 description 1
- YLQBMQCUIZJEEH-UHFFFAOYSA-N tetrahydrofuran Natural products C=1C=COC=1 YLQBMQCUIZJEEH-UHFFFAOYSA-N 0.000 description 1
- 229930003799 tocopherol Natural products 0.000 description 1
- 239000011732 tocopherol Substances 0.000 description 1
- 235000019149 tocopherols Nutrition 0.000 description 1
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- UFTFJSFQGQCHQW-UHFFFAOYSA-N triformin Chemical compound O=COCC(OC=O)COC=O UFTFJSFQGQCHQW-UHFFFAOYSA-N 0.000 description 1
- 239000000080 wetting agent Substances 0.000 description 1
- QUEDXNHFTDJVIY-UHFFFAOYSA-N γ-tocopherol Chemical class OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1 QUEDXNHFTDJVIY-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C259/00—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C259/00—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups
- C07C259/04—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids
- C07C259/06—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids having carbon atoms of hydroxamic groups bound to hydrogen atoms or to acyclic carbon atoms
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH302496 | 1996-12-10 | ||
| GBGB9625878.5A GB9625878D0 (en) | 1996-12-12 | 1996-12-12 | Compositions |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CZ204499A3 true CZ204499A3 (cs) | 1999-09-15 |
Family
ID=25691970
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CZ992044A CZ204499A3 (cs) | 1996-12-10 | 1997-12-08 | Přípravek obsahující polymorfní formy desferrioxaminu a způsob jeho přípravy |
Country Status (15)
| Country | Link |
|---|---|
| EP (1) | EP0944586A2 (es) |
| KR (1) | KR20000069376A (es) |
| CN (1) | CN1239946A (es) |
| AR (1) | AR009655A1 (es) |
| AU (1) | AU5983998A (es) |
| BR (1) | BR9713570A (es) |
| CA (1) | CA2274761A1 (es) |
| CO (1) | CO4910160A1 (es) |
| CZ (1) | CZ204499A3 (es) |
| ID (1) | ID22388A (es) |
| IL (1) | IL130203A0 (es) |
| PE (1) | PE27799A1 (es) |
| PL (1) | PL334316A1 (es) |
| TR (1) | TR199901260T2 (es) |
| WO (1) | WO1998025887A2 (es) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1251837A2 (en) * | 1999-12-23 | 2002-10-30 | Neurochem, Inc. | Compounds and methods for modulating cerebral amyloid angiopathy |
| GB0117645D0 (en) * | 2001-07-19 | 2001-09-12 | Isis Innovation | Therapeutic stratergies for prevention and treatment of alzheimers disease |
| DE10223913A1 (de) * | 2002-05-29 | 2003-12-11 | Bayer Cropscience Ag | Verfahren zur Herstellung spezifischer Kristallmodifikationen polymorpher Substanzen |
| WO2017068090A1 (en) | 2015-10-23 | 2017-04-27 | Vifor (International) Ag | Novel ferroportin inhibitors |
| JOP20180036A1 (ar) | 2017-04-18 | 2019-01-30 | Vifor Int Ag | أملاح لمثبطات فروبورتين جديدة |
| TW202102478A (zh) | 2019-04-01 | 2021-01-16 | 瑞士商威佛（國際）股份有限公司 | 新穎的鐵螯合物 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH438351A (de) * | 1959-09-25 | 1967-06-30 | Ciba Geigy | Verfahren zur Herstellung neuer Wuchsstoffe |
| FR1898M (fr) * | 1961-04-07 | 1963-07-08 | Ciba Geigy | Nouvelle substance utilisable en thérapeutique. |
| GB9211779D0 (en) * | 1992-06-03 | 1992-07-15 | Ciba Geigy Ag | Amine salts |
-
1997
- 1997-12-05 PE PE1997001097A patent/PE27799A1/es not_active Application Discontinuation
- 1997-12-05 AR ARP970105722A patent/AR009655A1/es unknown
- 1997-12-08 EP EP97954727A patent/EP0944586A2/en not_active Withdrawn
- 1997-12-08 CN CN97180523A patent/CN1239946A/zh active Pending
- 1997-12-08 AU AU59839/98A patent/AU5983998A/en not_active Abandoned
- 1997-12-08 TR TR1999/01260T patent/TR199901260T2/xx unknown
- 1997-12-08 CZ CZ992044A patent/CZ204499A3/cs unknown
- 1997-12-08 WO PCT/EP1997/006849 patent/WO1998025887A2/en not_active Application Discontinuation
- 1997-12-08 IL IL13020397A patent/IL130203A0/xx unknown
- 1997-12-08 KR KR1019997005104A patent/KR20000069376A/ko not_active Application Discontinuation
- 1997-12-08 PL PL97334316A patent/PL334316A1/xx unknown
- 1997-12-08 ID IDW990473A patent/ID22388A/id unknown
- 1997-12-08 CA CA002274761A patent/CA2274761A1/en not_active Abandoned
- 1997-12-08 BR BR9713570-4A patent/BR9713570A/pt not_active Application Discontinuation
- 1997-12-10 CO CO97072069A patent/CO4910160A1/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP0944586A2 (en) | 1999-09-29 |
| TR199901260T2 (xx) | 1999-10-21 |
| ID22388A (id) | 1999-10-07 |
| CO4910160A1 (es) | 2000-04-24 |
| IL130203A0 (en) | 2000-06-01 |
| PE27799A1 (es) | 1999-03-18 |
| BR9713570A (pt) | 2000-03-14 |
| AR009655A1 (es) | 2000-04-26 |
| CA2274761A1 (en) | 1998-06-18 |
| WO1998025887A3 (en) | 1998-08-13 |
| CN1239946A (zh) | 1999-12-29 |
| KR20000069376A (ko) | 2000-11-25 |
| PL334316A1 (en) | 2000-02-14 |
| AU5983998A (en) | 1998-07-03 |
| WO1998025887A2 (en) | 1998-06-18 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PD00 | Pending as of 2000-06-30 in czech republic |