CZ20031596A3 - Deriváty substituovaného 2-fenylaminoimidazolinfenylketonu jako IP antagonistická činidla - Google Patents

Info

Publication number

CZ20031596A3

CZ20031596A3 CZ20031596A CZ20031596A CZ20031596A3 CZ 20031596 A3 CZ20031596 A3 CZ 20031596A3 CZ 20031596 A CZ20031596 A CZ 20031596A CZ 20031596 A CZ20031596 A CZ 20031596A CZ 20031596 A3 CZ20031596 A3 CZ 20031596A3

Authority

CZ

Czechia

Prior art keywords

phenyl

dihydro

ylamino

imidazol

compound

Prior art date

2000-11-14

Links

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• Global Dossier
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• 230000003042 antagnostic effect Effects 0.000 title 1
• XSDRNCZRJVKAFM-UHFFFAOYSA-N diphenylmethanone;n-phenyl-4,5-dihydro-1h-imidazol-2-amine Chemical class N1CCN=C1NC1=CC=CC=C1.C=1C=CC=CC=1C(=O)C1=CC=CC=C1 XSDRNCZRJVKAFM-UHFFFAOYSA-N 0.000 title 1
• 150000001875 compounds Chemical class 0.000 claims abstract description 167
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• 150000003839 salts Chemical class 0.000 claims abstract description 21
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• 229940044551 receptor antagonist Drugs 0.000 claims abstract description 13
• 239000012453 solvate Substances 0.000 claims abstract description 13
• 238000002360 preparation method Methods 0.000 claims abstract description 12
• SYSQUGFVNFXIIT-UHFFFAOYSA-N n-[4-(1,3-benzoxazol-2-yl)phenyl]-4-nitrobenzenesulfonamide Chemical class C1=CC([N+](=O)[O-])=CC=C1S(=O)(=O)NC1=CC=C(C=2OC3=CC=CC=C3N=2)C=C1 SYSQUGFVNFXIIT-UHFFFAOYSA-N 0.000 claims abstract description 10
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• -1 methylenedioxy, ethylenedioxy Chemical group 0.000 claims description 134
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• 125000002102 aryl alkyloxo group Chemical group 0.000 claims description 11
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• 125000005843 halogen group Chemical group 0.000 claims description 11
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• 125000002924 primary amino group Chemical group [H]N([H])* 0.000 claims description 9
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• 125000003854 p-chlorophenyl group Chemical group [H]C1=C([H])C(*)=C([H])C([H])=C1Cl 0.000 claims description 3
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