CZ20012973A3 - Agonisté dopamin D1 receptoru - Google Patents

Agonisté dopamin D1 receptoru Download PDF

Info

Publication number
CZ20012973A3
CZ20012973A3 CZ20012973A CZ20012973A CZ20012973A3 CZ 20012973 A3 CZ20012973 A3 CZ 20012973A3 CZ 20012973 A CZ20012973 A CZ 20012973A CZ 20012973 A CZ20012973 A CZ 20012973A CZ 20012973 A3 CZ20012973 A3 CZ 20012973A3
Authority
CZ
Czechia
Prior art keywords
hydrogen
chloro
tetrahydro
mmol
halogen
Prior art date
Application number
CZ20012973A
Other languages
Czech (cs)
English (en)
Inventor
Gary Tilbrook
Original Assignee
Cenes Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cenes Limited filed Critical Cenes Limited
Publication of CZ20012973A3 publication Critical patent/CZ20012973A3/cs

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/16—Benzazepines; Hydrogenated benzazepines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Psychology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
CZ20012973A 1999-02-17 2000-02-17 Agonisté dopamin D1 receptoru CZ20012973A3 (cs)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB9903671.7A GB9903671D0 (en) 1999-02-17 1999-02-17 Dopamine D-1 receptor agonist compounds

Publications (1)

Publication Number Publication Date
CZ20012973A3 true CZ20012973A3 (cs) 2002-01-16

Family

ID=10847990

Family Applications (1)

Application Number Title Priority Date Filing Date
CZ20012973A CZ20012973A3 (cs) 1999-02-17 2000-02-17 Agonisté dopamin D1 receptoru

Country Status (17)

Country Link
EP (1) EP1157009A1 (xx)
JP (1) JP2002537288A (xx)
KR (1) KR20010108228A (xx)
CN (1) CN1142916C (xx)
AU (1) AU767332B2 (xx)
BR (1) BR0008329A (xx)
CA (1) CA2363695A1 (xx)
CZ (1) CZ20012973A3 (xx)
EA (1) EA004745B1 (xx)
GB (1) GB9903671D0 (xx)
HU (1) HUP0200057A3 (xx)
IL (1) IL144810A0 (xx)
MX (1) MXPA01008294A (xx)
NO (1) NO20013978D0 (xx)
PL (1) PL349838A1 (xx)
WO (1) WO2000049000A1 (xx)
ZA (1) ZA200106478B (xx)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0130576D0 (en) * 2001-12-20 2002-02-06 Cenes Ltd Dopamine D1 receptor agonist pro-drug compounds & derivatives
KR101594898B1 (ko) 2005-07-15 2016-02-18 알바니 몰레큘라 리써치, 인크. 아릴- 및 헤테로아릴-치환된 테트라히드로벤자제핀, 및 노르에피네프린, 도파민 및 세로토닌의 재흡수를 차단하기 위한 용도
AU2006278514A1 (en) * 2005-08-03 2007-02-15 Mia Levite Killing human lymphoma and leukemia cancer cells and TCR-activated normal human cells by dopamine D1R agonists
CN101684096A (zh) * 2008-09-23 2010-03-31 中国科学院上海药物研究所 一类新型苯并氮杂卓类化合物及其制备方法和用途
CN102276531A (zh) * 2011-05-30 2011-12-14 扬子江药业集团广州海瑞药业有限公司 一种甲磺酸非诺多泮的制备方法
RS59018B1 (sr) 2013-06-27 2019-08-30 Pfizer Heteroaromatična jedinjenja i njihova upotreba kao dopamin d1 liganada

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1561305A (en) * 1975-07-02 1980-02-20 Smithkline Corp Benzazepine derivatives and pharmeceutical compositions containing them
US4111957A (en) * 1977-02-02 1978-09-05 Smithkline Corporation Substituted 1-thienyl and furyl-2,3,4,5-tetrahydro-1H-3-benzazepine compounds
US4265889A (en) * 1978-05-05 1981-05-05 Smithkline Corporation 6-Lower alkyl-7,8-dihydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepines
US4707483A (en) * 1985-12-20 1987-11-17 Smithkline Beckman Corporation 1-phenyl-3-benzazepines and their use for treating gastrointestinal motility disorders
US4861771A (en) * 1989-01-27 1989-08-29 Smithkline Beckman Corporation Carbamates of 6-chloro-7,8-dihydroxy-1-(4'-hydroxyphenyl)-2,3,4,5-tetrahydro-1H-3-benzazepine as prodrugs

Also Published As

Publication number Publication date
KR20010108228A (ko) 2001-12-07
EA004745B1 (ru) 2004-08-26
AU767332B2 (en) 2003-11-06
ZA200106478B (en) 2002-02-07
IL144810A0 (en) 2002-06-30
GB9903671D0 (en) 1999-04-14
HUP0200057A2 (en) 2002-08-28
EP1157009A1 (en) 2001-11-28
AU2563200A (en) 2000-09-04
MXPA01008294A (es) 2002-07-02
WO2000049000A1 (en) 2000-08-24
CN1142916C (zh) 2004-03-24
PL349838A1 (en) 2002-09-23
NO20013978L (no) 2001-08-15
BR0008329A (pt) 2002-01-29
CA2363695A1 (en) 2000-08-24
EA200100783A1 (ru) 2002-02-28
CN1341102A (zh) 2002-03-20
NO20013978D0 (no) 2001-08-15
JP2002537288A (ja) 2002-11-05
HUP0200057A3 (en) 2004-03-29

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