CY365A - 6-Methylene-tetracyclines and method of preparing same - Google Patents

6-Methylene-tetracyclines and method of preparing same

Info

Publication number
CY365A
CY365A CY36567A CY36567A CY365A CY 365 A CY365 A CY 365A CY 36567 A CY36567 A CY 36567A CY 36567 A CY36567 A CY 36567A CY 365 A CY365 A CY 365A
Authority
CY
Cyprus
Prior art keywords
tetracyclines
methylene
preparing same
preparing
same
Prior art date
Application number
CY36567A
Other languages
English (en)
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27567787&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CY365(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from US76441A external-priority patent/US2984686A/en
Application filed by Pfizer filed Critical Pfizer
Publication of CY365A publication Critical patent/CY365A/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/65—Tetracyclines
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29D—PRODUCING PARTICULAR ARTICLES FROM PLASTICS OR FROM SUBSTANCES IN A PLASTIC STATE
    • B29D23/00—Producing tubular articles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D33/00—Details of, or accessories for, sacks or bags
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
    • F16L—PIPES; JOINTS OR FITTINGS FOR PIPES; SUPPORTS FOR PIPES, CABLES OR PROTECTIVE TUBING; MEANS FOR THERMAL INSULATION IN GENERAL
    • F16L11/00—Hoses, i.e. flexible pipes
    • F16L11/04—Hoses, i.e. flexible pipes made of rubber or flexible plastics
CY36567A 1960-05-23 1967-02-02 6-Methylene-tetracyclines and method of preparing same CY365A (en)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US3123660A 1960-05-23 1960-05-23
US3841460A 1960-06-29 1960-06-29
US7285760A 1960-12-01 1960-12-01
US7287560A 1960-12-01 1960-12-01
US76441A US2984686A (en) 1960-12-19 1960-12-19 6-deoxy-6-demethyl-6-methylene-5-oxytetracyclines
US8705961A 1961-02-06 1961-02-06
US106146A US3200149A (en) 1960-05-23 1961-05-05 alpha-6-deoxytetracycline derivatives and process

Publications (1)

Publication Number Publication Date
CY365A true CY365A (en) 1967-02-02

Family

ID=27567787

Family Applications (4)

Application Number Title Priority Date Filing Date
CY36567A CY365A (en) 1960-05-23 1967-02-02 6-Methylene-tetracyclines and method of preparing same
CY36667A CY366A (en) 1960-05-23 1967-02-02 11a-Halo-6-methylenetetracyclines and method of preparing same
CY38167A CY381A (en) 1960-05-23 1967-03-08 Tetracycline derivatives
CY48069A CY480A (en) 1960-05-23 1969-04-10 11beta-Halo-tetracycline-6,12 hemiketals

Family Applications After (3)

Application Number Title Priority Date Filing Date
CY36667A CY366A (en) 1960-05-23 1967-02-02 11a-Halo-6-methylenetetracyclines and method of preparing same
CY38167A CY381A (en) 1960-05-23 1967-03-08 Tetracycline derivatives
CY48069A CY480A (en) 1960-05-23 1969-04-10 11beta-Halo-tetracycline-6,12 hemiketals

Country Status (10)

Country Link
US (1) US3200149A (de)
CH (3) CH434238A (de)
CY (4) CY365A (de)
DE (3) DE1283834B (de)
FI (1) FI40534B (de)
FR (1) FR1430859A (de)
GB (4) GB998294A (de)
MY (4) MY6700047A (de)
OA (1) OA00136A (de)
SE (1) SE302119B (de)

Families Citing this family (54)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3444198A (en) * 1967-02-13 1969-05-13 Pfizer & Co C Process for producing alpha-6-deoxytetracyclines
US4089900A (en) * 1967-09-13 1978-05-16 Pfizer Inc. Antimicrobial agents
DE1767891C3 (de) * 1968-06-28 1980-10-30 Pfizer Verfahren zur Herstellung von wäßrigen arzneilichen Lösungen für die parenterale, perorale und lokale Anwendung mit einem Gehalt an einem Tetracyclinderivat
BR6915425D0 (pt) * 1969-06-27 1973-01-16 Farmaceutici Italia Preparacao de cloro-metileno-tetraciclina
BE754596A (fr) * 1969-08-08 1971-02-08 Farmaceutici Italia Esters de la methylenetetracycline et procede de leur fabrication
BE755678R (fr) * 1969-09-04 1971-03-03 Farmaceutici Italia Esters de la methylenetetracycline et procede de leur fabrication
DK153393C (da) * 1970-07-03 1988-11-28 Ivan Villax Fremgangsmaade til fremstilling af metacyklin ved dehalogenering af et syreadditionssalt af 11a-klor-6-desoxy-6-demetyl-6-metylen-5-hydroxytetracyklin
US3795707A (en) * 1970-12-28 1974-03-05 Rachelle Labor Italia Spa Manufacture of alpha-6-deoxytetracyclines
GB1418137A (en) * 1972-02-24 1975-12-17 Ankerfarm Spa Process for the preparation of alpha-6-deoxytetracyclines
US3954862A (en) * 1973-04-20 1976-05-04 Pfizer Inc. Process for producing α-6-deoxytetracyclines
GB1459861A (en) * 1973-06-21 1976-12-31 Pfizer Process for 11a-dehalogenation of 11a-halotetracyclines
US3907890A (en) * 1974-05-28 1975-09-23 Pfizer Preparation of alpha-6-deoxy-5-hydroxytetracycline
US4001321A (en) * 1975-06-26 1977-01-04 Pfizer Inc. Preparation of α-6-deoxytetracyclines
YU41480B (en) * 1979-03-12 1987-08-31 Pliva Pharm & Chem Works Process for obtaining alpha-6-deoxy-5-hydroxytetracycline
DK386784A (da) * 1983-08-17 1985-02-18 Hovione Int Ltd Fremgangsmaade til fremstilling af alfa-6-desoxy-tetracykliner
HU188367B (en) * 1983-09-02 1986-04-28 Chinoin Gyogyszer Es Vegyeszeti Termekek Gyara Rt,Hu Process for preparing 6-demethy-6-deoxy-6-methylene-5-exytetracycline and 11a-chloro-derivative thereof
US4987242A (en) * 1988-10-28 1991-01-22 Jagmohan Khanna Hydrogenation catalyst useful in the production of alpha-6-deoxytetracyclines
US4973719A (en) * 1988-10-28 1990-11-27 Ranbaxy Laboratories Limited Process for the production of alpha-6-deoxytetracyclines
US5049683A (en) * 1989-01-04 1991-09-17 Houba, Inc. Process for the production of alpha-6-deoxytetracyclines
DE68900339D1 (de) * 1989-04-03 1991-11-21 Ranbaxy Lab Ltd Verfahren zur herstellung von alpha-6-deoxytetracyclinen.
US5281628A (en) * 1991-10-04 1994-01-25 American Cyanamid Company 9-amino-7-(substituted)-6-demethyl-6-deoxytetracyclines
USRE40183E1 (en) 1991-10-04 2008-03-25 Wyeth Holdings Corporation 7-Substituted-9-substituted amino-6-demethyl-6-deoxytetracyclines
US5494903A (en) * 1991-10-04 1996-02-27 American Cyanamid Company 7-substituted-9-substituted amino-6-demethyl-6-deoxytetracyclines
US5328902A (en) * 1992-08-13 1994-07-12 American Cyanamid Co. 7-(substituted)-9-[(substituted glycyl)amido]-6-demethyl-6-deoxytetracyclines
US5284963A (en) * 1992-08-13 1994-02-08 American Cyanamid Company Method of producing 7-(substituted)-9-[(substituted glycyl)-amidol]-6-demethyl-6-deoxytetra-cyclines
SG47520A1 (en) * 1992-08-13 1998-04-17 American Cyanamid Co New method for the production of 9-amino-6-demethyl-6-deoxytetracycline
US5442059A (en) * 1992-08-13 1995-08-15 American Cyanamid Company 9-[(substituted glycyl)amido)]-6-demethyl-6-deoxytetracyclines
US5420272A (en) * 1992-08-13 1995-05-30 American Cyanamid Company 7-(substituted)-8-(substituted)-9-](substituted glycyl)amido]-6-demethyl-6-deoxytetracyclines
US5371076A (en) * 1993-04-02 1994-12-06 American Cyanamid Company 9-[(substituted glycyl)amido]-6-(substituted)-5-hydroxy-6-deoxytetracyclines
US5538954A (en) * 1994-06-24 1996-07-23 A/S Dumex (Dumex Ltd.) Salts of tetracyclines
US20020123637A1 (en) * 1998-01-23 2002-09-05 Stuart B. Levy Pharmaceutically active compounds and methods of use thereof
ATE323671T1 (de) * 1999-09-14 2006-05-15 Tufts College Verfahren zur herstellung von substituierten tetracyclinen mit hilfe von auf übergangsmetalle basierten chemien
US8106225B2 (en) * 1999-09-14 2012-01-31 Trustees Of Tufts College Methods of preparing substituted tetracyclines with transition metal-based chemistries
US20020132798A1 (en) * 2000-06-16 2002-09-19 Nelson Mark L. 7-phenyl-substituted tetracycline compounds
US7056902B2 (en) * 2002-01-08 2006-06-06 Paratek Pharmaceuticals, Inc. 4-dedimethylamino tetracycline compounds
EP1503981A4 (de) * 2002-03-21 2007-08-15 Paratek Pharm Innc Substituierte tetracyclinverbindungen
KR20040094833A (ko) * 2002-03-29 2004-11-10 더 리서치 파운데이션 오브 스테이트 유니버시티 오브 뉴욕 비-항균성 테트라사이클린 동족체의 용도 및 박테리아외독소의 치료를 위한 이의 제형
EP2295404A3 (de) * 2003-07-09 2011-05-11 Paratek Pharmaceuticals, Inc. Substituierte Tetracyclin-Verbindungen
US20060287283A1 (en) * 2003-07-09 2006-12-21 Paratek Pharmaceuticals, Inc. Prodrugs of 9-aminomethyl tetracycline compounds
UA83266C2 (en) 2003-12-08 2008-06-25 Уайет Oxazole derivatives of tetracyclines
MX2007009863A (es) 2005-02-15 2007-09-04 Wyeth Corp Tetraciclinas 9-sustituidas.
AR057033A1 (es) * 2005-05-27 2007-11-14 Wyeth Corp Tigeciclina y metodos para preparar 9-nitrominociclina
AR057032A1 (es) * 2005-05-27 2007-11-14 Wyeth Corp Tigeciclina y metodos de preparacion
AR057324A1 (es) * 2005-05-27 2007-11-28 Wyeth Corp Tigeciclina y metodos para preparar 9-aminominociclina
CN101291916A (zh) * 2005-08-31 2008-10-22 惠氏公司 甘氨酰环素的9-氨基羰基取代衍生物
CN101678108A (zh) * 2007-03-23 2010-03-24 分子研究中心公司 包含四环素类的抗炎组合物及其用途
PT2271348T (pt) * 2008-03-28 2018-04-16 Paratek Pharm Innc Formulação de comprimido oral de composto de tetraciclina
TW202216656A (zh) * 2008-05-23 2022-05-01 美商Ｐｒｔｋ Ｓｐｖ２公司 四環素化合物之甲苯磺酸鹽及同素異形體
RU2647972C2 (ru) 2010-05-12 2018-03-21 Ремпекс Фармацеутикалс, Инк. Тетрациклиновая композиция
CN101967108B (zh) * 2010-09-13 2013-06-19 苏春华 一种美他环素的衍生物
CN102086165B (zh) * 2010-12-29 2013-06-19 开封制药(集团)有限公司 Pd催化剂在生产强力霉素氢化工艺中的应用
PT108978B (pt) 2015-11-24 2020-03-09 Hovione Farm S A Sais de tetraciclinas
CN111732522B (zh) * 2020-07-21 2022-10-18 山东国邦药业有限公司 一种脱氧土霉素的制备方法
WO2023205787A1 (en) * 2022-04-22 2023-10-26 Mork Benjamin V Compositions and methods for remediation using dithionite and activated carbons

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE566456A (de) *
DE1073482B (de) * 1960-01-21 American Cyanamid Company New York N Y (V St A) \ertr Dr F Zumstem Dipl Chem Dr rer nat E Assmann und Dipl Chem Dr R Koe nigsberger Pat Anwalte München 2 Verfahren zur Herstellung von Tetracyclmen und ihren 5a Epimeren
BE572236A (de) *
BE565025A (de) *
BE572584A (de) *
DE932670C (de) * 1952-10-23 1955-09-05 Pfizer & Co C Verfahren zur Herstellung von Tetracyclin und seinen Salzen
DE1011417B (de) * 1954-01-15 1957-07-04 Pfizer & Co C Verfahren zur Herstellung von Anhydrodesdimethylaminochlortetracyclin bzw. Anhydrodesdimethylaminotetracyclin
US2731497A (en) * 1954-05-14 1956-01-17 American Cyanamid Co Production of tetracycline
DE1007775B (de) * 1955-02-12 1957-05-09 Pfizer & Co C Verfahren zur Herstellung von Tetracyclin und seinen Salzen
CH365484A (fr) * 1956-05-28 1962-11-15 American Cyanamid Co Procédé de préparation d'une substance antibiotique
GB855170A (en) * 1957-03-01 1960-11-30 American Cyanamid Co 6-demethyl-6-deoxytetracycline and the 4-epimers thereof
US3005023A (en) * 1957-04-05 1961-10-17 American Cyanamid Co Production of tetracycline
US3036129A (en) * 1959-10-09 1962-05-22 American Cyanamid Co Preparation of 7-halo-6-deoxy-tetracyclines
US3019260A (en) * 1959-05-13 1962-01-30 American Cyanamid Co Process for the catalytic reduction of 6-hydroxy hydronaphthacenes
US2976318A (en) * 1959-05-18 1961-03-21 Pfizer & Co C Tetracycline derivatives and process of producing the same

Also Published As

Publication number Publication date
FR1430859A (de) 1966-05-25
MY6900209A (en) 1969-12-31
GB995031A (en)
DE1300934B (de) 1969-08-14
GB995032A (en) 1965-06-10
CY366A (en) 1967-02-02
US3200149A (en) 1965-08-10
DE1298522B (de) 1969-07-03
FI40534B (de) 1968-11-30
GB995033A (en) 1965-06-10
CH459189A (de) 1968-07-15
CY480A (en) 1969-04-10
CY381A (en) 1967-03-08
MY6700048A (en) 1967-12-31
MY6700047A (en) 1967-12-31
DE1283834B (de) 1968-11-28
CH444853A (de) 1967-10-15
GB998294A (en) 1965-07-14
SE302119B (de) 1968-07-08
CH434238A (de) 1967-04-30
OA00136A (fr) 1966-03-15
MY7400226A (en) 1974-12-31

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